Research Topics
| Shibu YoosephSummaryAffiliation: J. Craig Venter Institute Country: USA Publications
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Detail Information
Publications
The Sorcerer II Global Ocean Sampling expedition: expanding the universe of protein familiesShibu Yooseph
J Craig Venter Institute, Rockville, Maryland, United States of America
PLoS Biol 5:e16. 2007..Our analysis indicates that new families are being discovered at a rate that is linear or almost linear with the addition of new sequences, implying that we are still far from discovering all protein families in nature...
The Sorcerer II Global Ocean Sampling Expedition: metagenomic characterization of viruses within aquatic microbial samplesShannon J Williamson
J Craig Venter Institute, Rockville, Maryland, USA
PLoS ONE 3:e1456. 2008....
The Sorcerer II Global Ocean Sampling expedition: northwest Atlantic through eastern tropical PacificDouglas B Rusch
J Craig Venter Institute, Rockville, Maryland, United States of America
PLoS Biol 5:e77. 2007..Specific functional adaptations can be identified both within individual ribotypes and across the entire community, including proteorhodopsin spectral tuning and the presence or absence of the phosphate-binding gene PstS...
Genomic and functional adaptation in surface ocean planktonic prokaryotesShibu Yooseph
J Craig Venter Institute, Rockville, Maryland 20850, USA
Nature 468:60-6. 2010..Their genomic features also lead us to propose that one method used to avoid predation by viruses and/or bacterivores is by means of slow growth and the maintenance of low biomass...
Gene identification and protein classification in microbial metagenomic sequence data via incremental clusteringShibu Yooseph
J, Craig Venter Institute, 9704 Medical Center Drive, Rockville, MD 20850, USA
BMC Bioinformatics 9:182. 2008..and consequently gene identification is challenging. The vast amount of sequence data also requires faster protein family classification tools...
Metagenomic exploration of viruses throughout the Indian OceanShannon J Williamson
Microbial and Environmental Genomics, J Craig Venter Institute, San Diego, California, USA
PLoS ONE 7:e42047. 2012..This is the first study to holistically explore virioplankton dynamics across multiple size classes and provides unprecedented insight into virus diversity, metabolic potential and virus-host interactions...
Analyses of the microbial diversity across the human microbiomeKelvin Li
J Craig Venter Institute, Rockville, Maryland, United States of America
PLoS ONE 7:e32118. 2012....
Discovery of [NiFe] hydrogenase genes in metagenomic DNA: cloning and heterologous expression in Thiocapsa roseopersicinaGergely Maroti
J Craig Venter Institute, 9704 Medical Center Drive, Rockville, MD 20850, USA
Appl Environ Microbiol 75:5821-30. 2009..It also provides a model for functionally analyzing novel enzymes from environmental microbes in a culture-independent manner...
Zinc finger gene clusters and tandem gene duplicationMengxiang Tang
ACLARA BioSciences, 1288 Pear Street, Mountain View, CA 94043, USA
J Comput Biol 9:429-46. 2002..We provide algorithms to reconstruct a duplication model for a given data set. We use our method to hypothesize the series of duplication events that may have produced the ZNF45 family that appears on human chromosome 19...
ThurGood: evaluating assembly-to-assembly mappingHagit Shatkay
School of Computing, Queen s University, Kingston, Ontario, Canada
J Comput Biol 11:800-11. 2004..These tools have already proved useful in the evaluation and ranking of several methods for assembly-to-assembly mapping, which were recently used to map multiple versions of the human genome to each other (Istrail et aL, 2004)...
A comparison of whole-genome shotgun-derived mouse chromosome 16 and the human genomeRichard J Mural
Celera Genomics, 45 West Gude Drive, Rockville, MD 20850, USA
Science 296:1661-71. 2002....
Evolution of allostery in the cyclic nucleotide binding moduleNatarajan Kannan
Department of Chemistry and Biochemistry, University of California, Gilman Drive, La Jolla, California 92093 0654, USA
Genome Biol 8:R264. 2007..In this study, we analyze the evolutionary information embedded in genomic sequences to explore the diversity of signaling through the CNB domain and also how the CNB domain elicits a cellular response upon binding to cAMP...
A note on efficient computation of haplotypes via perfect phylogenyVineet Bafna
Department of Computer Science and Engineering, University of California at San Diego, La Jolla, CA 92093, USA
J Comput Biol 11:858-66. 2004..For the second problem of computing a PPH solution that minimizes the number of distinct haplotypes, we show that the problem is NP-hard using a reduction from Vertex Cover (Garey and Johnson, 1979)...
Whole-genome shotgun assembly and comparison of human genome assembliesSorin Istrail
Applied Biosystems, 45 West Gude Drive, Rockville, MD 20850, USA
Proc Natl Acad Sci U S A 101:1916-21. 2004..The Celera results provide more order and orientation, and the consortium sequence provides better coverage of exact and nearly exact repeats...
Haplotyping as perfect phylogeny: a direct approachVineet Bafna
The Center for Advancement of Genomics, 1901 Research Blvd, 6th Floor, Rockville, MD 20850, USA
J Comput Biol 10:323-40. 2003....
Viral photosynthetic reaction center genes and transcripts in the marine environmentItai Sharon
Faculty of Biology, Technion Israel Institute of Technology, Haifa, Israel
ISME J 1:492-501. 2007..Furthermore, we show that different viral psbA genes are expressed in the environment...
