Kelvin Li

Summary

Affiliation: J. Craig Venter Institute
Country: USA

Publications

  1. pmc Novel computational methods for increasing PCR primer design effectiveness in directed sequencing
    Kelvin Li
    The J, Craig Venter Institute, 9704 Medical Center Drive, Rockville, MD 20850, USA
    BMC Bioinformatics 9:191. 2008
  2. doi request reprint Primer design for RT-PCR
    Kelvin Li
    J Craig Venter Institute, Rockville, MD, USA
    Methods Mol Biol 630:271-99. 2010
  3. pmc Automated degenerate PCR primer design for high-throughput sequencing improves efficiency of viral sequencing
    Kelvin Li
    The J, Craig Venter Institute, Rockville, MD 20850, USA
    Virol J 9:261. 2012
  4. pmc VariantClassifier: A hierarchical variant classifier for annotated genomes
    Kelvin Li
    The J, Craig Venter Institute, 9704 Medical Center Drive, Rockville, MD 20850, USA
    BMC Res Notes 3:191. 2010
  5. pmc ANDES: Statistical tools for the ANalyses of DEep Sequencing
    Kelvin Li
    The J, Craig Venter Institute, 9704 Medical Center Drive, Rockville, MD 20850, USA
    BMC Res Notes 3:199. 2010
  6. pmc Genetic variation in an individual human exome
    Pauline C Ng
    J Craig Venter Institute, Rockville, Maryland, United States of America
    PLoS Genet 4:e1000160. 2008
  7. pmc Aggressive assembly of pyrosequencing reads with mates
    Jason R Miller
    The J Craig Venter Institute, 9712 Medical Center Drive, Rockville MD 20850, USA
    Bioinformatics 24:2818-24. 2008
  8. pmc The Sorcerer II Global Ocean Sampling expedition: northwest Atlantic through eastern tropical Pacific
    Douglas B Rusch
    J Craig Venter Institute, Rockville, Maryland, United States of America
    PLoS Biol 5:e77. 2007
  9. pmc METAREP: JCVI metagenomics reports--an open source tool for high-performance comparative metagenomics
    Johannes Goll
    The J Craig Venter Institute, Rockville, MD 20850, USA
    Bioinformatics 26:2631-2. 2010
  10. pmc Analyses of the stability and core taxonomic memberships of the human microbiome
    Kelvin Li
    J Craig Venter Institute, Rockville, Maryland, United States of America
    PLoS ONE 8:e63139. 2013

Collaborators

Detail Information

Publications13

  1. pmc Novel computational methods for increasing PCR primer design effectiveness in directed sequencing
    Kelvin Li
    The J, Craig Venter Institute, 9704 Medical Center Drive, Rockville, MD 20850, USA
    BMC Bioinformatics 9:191. 2008
    ..This inefficient approach to primer design is further intensified in a high-throughput laboratory, where hundreds of genes may be targeted in one experiment...
  2. doi request reprint Primer design for RT-PCR
    Kelvin Li
    J Craig Venter Institute, Rockville, MD, USA
    Methods Mol Biol 630:271-99. 2010
    ....
  3. pmc Automated degenerate PCR primer design for high-throughput sequencing improves efficiency of viral sequencing
    Kelvin Li
    The J, Craig Venter Institute, Rockville, MD 20850, USA
    Virol J 9:261. 2012
    ..To successfully select a large set of degenerate PCR primers necessary to tile across an entire viral genome and maximize their success, this process is best performed computationally...
  4. pmc VariantClassifier: A hierarchical variant classifier for annotated genomes
    Kelvin Li
    The J, Craig Venter Institute, 9704 Medical Center Drive, Rockville, MD 20850, USA
    BMC Res Notes 3:191. 2010
    ..An easy-to-use tool for quickly assessing the potential importance of these discovered variants becomes ever important...
  5. pmc ANDES: Statistical tools for the ANalyses of DEep Sequencing
    Kelvin Li
    The J, Craig Venter Institute, 9704 Medical Center Drive, Rockville, MD 20850, USA
    BMC Res Notes 3:199. 2010
    ..While this visual format is intuitive for a small set of aligned sequences, the representation quickly becomes cumbersome as sequencing depths cover loci hundreds or thousands of reads deep...
  6. pmc Genetic variation in an individual human exome
    Pauline C Ng
    J Craig Venter Institute, Rockville, Maryland, United States of America
    PLoS Genet 4:e1000160. 2008
    ..We present an approach to analyze the coding variation in humans by proposing multiple bioinformatic methods to hone in on possible functional variation...
  7. pmc Aggressive assembly of pyrosequencing reads with mates
    Jason R Miller
    The J Craig Venter Institute, 9712 Medical Center Drive, Rockville MD 20850, USA
    Bioinformatics 24:2818-24. 2008
    ..This is true even of pyrosequencing mated and unmated read combinations. Without special modifications, assemblers tuned for homogeneous sequence data may perform poorly on hybrid data...
  8. pmc The Sorcerer II Global Ocean Sampling expedition: northwest Atlantic through eastern tropical Pacific
    Douglas B Rusch
    J Craig Venter Institute, Rockville, Maryland, United States of America
    PLoS Biol 5:e77. 2007
    ..Specific functional adaptations can be identified both within individual ribotypes and across the entire community, including proteorhodopsin spectral tuning and the presence or absence of the phosphate-binding gene PstS...
  9. pmc METAREP: JCVI metagenomics reports--an open source tool for high-performance comparative metagenomics
    Johannes Goll
    The J Craig Venter Institute, Rockville, MD 20850, USA
    Bioinformatics 26:2631-2. 2010
    ..Summaries can be exported as tab-delimited files, publication quality plots in PDF format. A data management layer allows collaborative data analysis and result sharing...
  10. pmc Analyses of the stability and core taxonomic memberships of the human microbiome
    Kelvin Li
    J Craig Venter Institute, Rockville, Maryland, United States of America
    PLoS ONE 8:e63139. 2013
    ....
  11. pmc Analyses of the microbial diversity across the human microbiome
    Kelvin Li
    J Craig Venter Institute, Rockville, Maryland, United States of America
    PLoS ONE 7:e32118. 2012
    ....
  12. ncbi request reprint A comparison of whole-genome shotgun-derived mouse chromosome 16 and the human genome
    Richard J Mural
    Celera Genomics, 45 West Gude Drive, Rockville, MD 20850, USA
    Science 296:1661-71. 2002
    ....
  13. pmc A Sanger/pyrosequencing hybrid approach for the generation of high-quality draft assemblies of marine microbial genomes
    Susanne M D Goldberg
    J Craig Venter Institute, 9704 Medical Center Drive, Rockville, MD 20850, USA
    Proc Natl Acad Sci U S A 103:11240-5. 2006
    ....