Christopher L Dupont

Summary

Affiliation: J. Craig Venter Institute
Country: USA

Publications

  1. ncbi History of biological metal utilization inferred through phylogenomic analysis of protein structures
    Christopher L Dupont
    Microbial and Environmental Genomics Group, J Craig Venter Institute, La Jolla, CA 92121, USA
    Proc Natl Acad Sci U S A 107:10567-72. 2010
  2. ncbi Genomes of uncultured eukaryotes: sorting FACS from fiction
    Alexandra Z Worden
    Monterey Bay Aquarium Research Institute, 7700 Sandholdt Road, Moss Landing, CA 95039, USA
    Genome Biol 12:117. 2011
  3. ncbi Genomic insights to SAR86, an abundant and uncultivated marine bacterial lineage
    Chris L Dupont
    Microbial and Environmental Genomics, J Craig Venter Institute, San Diego, CA 92121, USA
    ISME J 6:1186-99. 2012
  4. ncbi Genomic and functional adaptation in surface ocean planktonic prokaryotes
    Shibu Yooseph
    J Craig Venter Institute, Rockville, Maryland 20850, USA
    Nature 468:60-6. 2010
  5. ncbi Modern proteomes contain putative imprints of ancient shifts in trace metal geochemistry
    Christopher L Dupont
    Department of Chemistry and Biochemistry, The Scripps Institution of Oceanography, University of California at San Diego, La Jolla, CA 92093, USA
    Proc Natl Acad Sci U S A 103:17822-7. 2006
  6. ncbi Characterization of Prochlorococcus clades from iron-depleted oceanic regions
    Douglas B Rusch
    J Craig Venter Institute, Rockville, MD 20855, USA
    Proc Natl Acad Sci U S A 107:16184-9. 2010
  7. ncbi Evolution and metabolic significance of the urea cycle in photosynthetic diatoms
    Andrew E Allen
    J Craig Venter Institute, San Diego, California 92121, USA
    Nature 473:203-7. 2011
  8. ncbi Transcriptomic analysis of metabolic function in the giant kelp, Macrocystis pyrifera, across depth and season
    Talina Konotchick
    J Craig Venter Institute, 10355 Science Center Drive, San Diego, CA, USA
    New Phytol 198:398-407. 2013
  9. ncbi Efficient de novo assembly of single-cell bacterial genomes from short-read data sets
    Hamidreza Chitsaz
    Department of Computer Science, University of California, La Jolla, CA, USA
    Nat Biotechnol 29:915-21. 2011
  10. ncbi Ni uptake and limitation in marine Synechococcus strains
    Christopher L Dupont
    Scripps Institution of Oceanography, University of California, San Diego, La Jolla, California 92093, USA
    Appl Environ Microbiol 74:23-31. 2008

Collaborators

Detail Information

Publications12

  1. ncbi History of biological metal utilization inferred through phylogenomic analysis of protein structures
    Christopher L Dupont
    Microbial and Environmental Genomics Group, J Craig Venter Institute, La Jolla, CA 92121, USA
    Proc Natl Acad Sci U S A 107:10567-72. 2010
    ..The results presented here provide an evolutionary timeline based on genomic characteristics, and key hypotheses can be tested by alternative geochemical methods...
  2. ncbi Genomes of uncultured eukaryotes: sorting FACS from fiction
    Alexandra Z Worden
    Monterey Bay Aquarium Research Institute, 7700 Sandholdt Road, Moss Landing, CA 95039, USA
    Genome Biol 12:117. 2011
    ..A recent study explores the genome content of uncultured unicellular marine eukaryotes and provides insights about interactions between uncultured eukaryotes and other biological entities...
  3. ncbi Genomic insights to SAR86, an abundant and uncultivated marine bacterial lineage
    Chris L Dupont
    Microbial and Environmental Genomics, J Craig Venter Institute, San Diego, CA 92121, USA
    ISME J 6:1186-99. 2012
    ..Like the abundant planktonic marine bacterial clade SAR11, SAR86 exhibits metabolic streamlining, but also a distinct carbon compound specialization, possibly avoiding competition...
  4. ncbi Genomic and functional adaptation in surface ocean planktonic prokaryotes
    Shibu Yooseph
    J Craig Venter Institute, Rockville, Maryland 20850, USA
    Nature 468:60-6. 2010
    ..Their genomic features also lead us to propose that one method used to avoid predation by viruses and/or bacterivores is by means of slow growth and the maintenance of low biomass...
  5. ncbi Modern proteomes contain putative imprints of ancient shifts in trace metal geochemistry
    Christopher L Dupont
    Department of Chemistry and Biochemistry, The Scripps Institution of Oceanography, University of California at San Diego, La Jolla, CA 92093, USA
    Proc Natl Acad Sci U S A 103:17822-7. 2006
    ..We hypothesize that these conserved trends are proteomic imprints of changes in trace metal bioavailability in the ancient ocean that highlight a major evolutionary shift in biological trace metal usage...
  6. ncbi Characterization of Prochlorococcus clades from iron-depleted oceanic regions
    Douglas B Rusch
    J Craig Venter Institute, Rockville, MD 20855, USA
    Proc Natl Acad Sci U S A 107:16184-9. 2010
    ....
  7. ncbi Evolution and metabolic significance of the urea cycle in photosynthetic diatoms
    Andrew E Allen
    J Craig Venter Institute, San Diego, California 92121, USA
    Nature 473:203-7. 2011
    ..The diatom ornithine-urea cycle therefore represents a key pathway for anaplerotic carbon fixation into nitrogenous compounds that are essential for diatom growth and for the contribution of diatoms to marine productivity...
  8. ncbi Transcriptomic analysis of metabolic function in the giant kelp, Macrocystis pyrifera, across depth and season
    Talina Konotchick
    J Craig Venter Institute, 10355 Science Center Drive, San Diego, CA, USA
    New Phytol 198:398-407. 2013
    ..g. nitrite reductase) were upregulated at depth compared with the surface, supporting a conceptual biological model of depth-dependent physiology...
  9. ncbi Efficient de novo assembly of single-cell bacterial genomes from short-read data sets
    Hamidreza Chitsaz
    Department of Computer Science, University of California, La Jolla, CA, USA
    Nat Biotechnol 29:915-21. 2011
    ..Our approach enables acquisition of genome assemblies for individual uncultivated bacteria using only short reads, providing cell-specific genetic information absent from metagenomic studies...
  10. ncbi Ni uptake and limitation in marine Synechococcus strains
    Christopher L Dupont
    Scripps Institution of Oceanography, University of California, San Diego, La Jolla, California 92093, USA
    Appl Environ Microbiol 74:23-31. 2008
    ..These results, combined with an analysis of fully sequenced marine cyanobacterial genomes, suggest that the growth of many marine Synechococcus and all Prochlorococcus strains is dependent upon Ni...
  11. ncbi Sequence analysis of a complete 1.66 Mb Prochlorococcus marinus MED4 genome cloned in yeast
    Christian Tagwerker
    Department of Synthetic Biology and Bioenergy, J Craig Venter Institute, 10355 Science Center Drive, San Diego, CA 92121, USA
    Nucleic Acids Res 40:10375-83. 2012
    ..We thus provide evidence of transformation, replication and maintenance of this 1.66 Mb intact bacterial genome in S. cerevisiae...
  12. ncbi Copper toxicity and the origin of bacterial resistance--new insights and applications
    Christopher L Dupont
    Microbial and Environmental Genomics, J Craig Venter Institute, San Diego, CA, USA
    Metallomics 3:1109-18. 2011
    ..In an "arms race," some pathogenic bacteria have evolved new mechanisms for copper resistance, which is relevant given renewed interest in the use of copper surfaces due to their antimicrobial properties...