Research Topics
| Dennis T ManganoSummaryAffiliation: Ischemia Research and Education Foundation Country: USA Publications
| Collaborators
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Detail Information
Publications
Post-reperfusion myocardial infarction: long-term survival improvement using adenosine regulation with acadesineDennis T Mangano
Ischemia Research and Education Foundation IREF, San Bruno, California 94066, USA
J Am Coll Cardiol 48:206-14. 2006..The purpose of this study was to assess the safety and efficacy of the adenosine regulating agent (ARA) acadesine for reducing long-term mortality among patients with post-reperfusion myocardial infarction (MI)...- The risk associated with aprotinin in cardiac surgeryDennis T Mangano
Ischemia Research and Education Foundation, San Bruno, Calif 94066, USA
N Engl J Med 354:353-65. 2006..This approach appears counterintuitive to the accepted medical treatment of the same condition--namely, fibrinolysis to limit thrombosis. Despite this concern, no independent, large-scale safety assessment has been undertaken... - Aspirin and mortality from coronary bypass surgeryDennis T Mangano
Ischemia Research and Education Foundation, San Francisco, CA 94134, USA
N Engl J Med 347:1309-17. 2002..Because platelet activation constitutes a pivotal mechanism for injury in patients with atherosclerosis, we assessed whether early treatment with aspirin could improve survival after coronary bypass surgery... - Mortality associated with aprotinin during 5 years following coronary artery bypass graft surgeryDennis T Mangano
Ischemia Research and Education Foundation, San Bruno, Calif 94066, USA
JAMA 297:471-9. 2007..Acute safety concerns have been raised recently regarding certain hemorrhage-sparing medications commonly used in cardiac surgery. However, no comprehensive data exist regarding their associations with long-term mortality... - Prevalence of risk factors, and not gender per se, determines short- and long-term survival after coronary artery bypass surgeryColleen Gorman Koch
Cleveland Clinic Foundation, OH, USA
J Cardiothorac Vasc Anesth 17:585-93. 2003..Studies that have compared postoperative survival in women and men beyond hospital discharge report disparate results with regard to the independent effect of gender per se on ultimate survival... - Perioperative medicine: NHLBI working group deliberations and recommendationsDennis T Mangano
Ischemia Research and Education Foundation, San Francisco, CA 94134, USA
J Cardiothorac Vasc Anesth 18:1-6. 2004 - Adverse gastrointestinal complications after cardiopulmonary bypass: can outcome be predicted from preoperative risk factors?Mary E McSweeney
Multicenter Study of Perioperative Ischemia Research Group and University of Wisconsin Medical School, Madison, WI, USA
Anesth Analg 98:1610-7, table of contents. 2004.... 
Pulse pressure and risk of adverse outcome in coronary bypass surgeryManuel L Fontes
Weill Medical College of Cornell University, Ischemia Research and Education Foundation 1111 Bayhill Dr, Suite 480, San Bruno, CA 94066, USA
Anesth Analg 107:1122-9. 2008..The relationship of PP and acute perioperative vascular outcome among patients having coronary artery bypass graft (CABG) surgery is less well known...
Hormone replacement therapy is safe in women undergoing coronary artery bypass graftingNancy A Nussmeier
Ischemia Research and Education Foundation, 1111 Bayhill Drive, Suite 480, San Bruno, CA 94066, USA
Tex Heart Inst J 32:507-14. 2005..01). We conclude that HRT administration before coronary artery bypass grafting does not increase women's risk of any adverse outcome...- Coronary artery bypass graft surgery--care globalization: the impact of national care on fatal and nonfatal outcomeElisabeth Ott
Multicenter Study of Perioperative Ischemia Research Group, San Bruno, Calif, USA
J Thorac Cardiovasc Surg 133:1242-51. 2007..In an international, prospective, observational study, we contrasted adverse vascular outcomes among four countries and then assessed practice pattern differences that may have contributed to these outcomes... - Efficacy and safety of the cyclooxygenase 2 inhibitors parecoxib and valdecoxib in patients undergoing coronary artery bypass surgeryElisabeth Ott
Ischemia Research and Education Foundation, San Francisco, CA 94143, USA
J Thorac Cardiovasc Surg 125:1481-92. 2003..We prospectively evaluated the safety and efficacy of a newly introduced cyclooxygenase 2 inhibitor in patients undergoing coronary artery bypass grafting surgery through a median sternotomy in a randomized clinical trial... - Risk index for perioperative renal dysfunction/failure: critical dependence on pulse pressure hypertensionSolomon Aronson
Duke University Medical Center, Durham, NC, USA
Circulation 115:733-42. 2007..An acute renal event after coronary bypass graft surgery is associated with high mortality and substantial additive cost... - The ongoing variability in blood transfusion practices in cardiac surgeryStephanie A Snyder-Ramos
Department of Anesthesiology, University of Heidelberg, Heidelberg, Germany
Transfusion 48:1284-99. 2008..Therefore, the objective of this evaluation was to compare the perioperative transfusion of blood components in cardiac surgery in multiple centers in different countries... - Preoperative statin therapy is associated with reduced cardiac mortality after coronary artery bypass graft surgeryCharles D Collard
Baylor College of Medicine, Division of Cardiovascular Anesthesiology, Texas Heart Institute, St Luke s Episcopal Hospital, Houston, Tex, USA
J Thorac Cardiovasc Surg 132:392-400. 2006.... - Impact of preoperative anemia on outcome in patients undergoing coronary artery bypass graft surgeryAlexander Kulier
Department of Anesthesiology and Intensive Care Medicine, Medical University of Graz, Graz, Austri
Circulation 116:471-9. 2007..Thus, we determined the effects of low preoperative hemoglobin and comorbidities on postoperative adverse outcomes in patients with coronary artery bypass graft in a large comprehensive multicenter study... - A multicenter risk index for atrial fibrillation after cardiac surgeryJoseph P Mathew
Multicenter Study of Perioperative Ischemia Research Group and Department of Anesthesiology, Duke University Medical Center, Durham, NC, USA
JAMA 291:1720-9. 2004..Atrial fibrillation is a common, but potentially preventable, complication following coronary artery bypass graft (CABG) surgery... - Judging the safety of aprotininDennis T Mangano
N Engl J Med 355:2261-2. 2006 - Impact of pexelizumab, an anti-C5 complement antibody, on total mortality and adverse cardiovascular outcomes in cardiac surgical patients undergoing cardiopulmonary bypassStanton K Shernan
Division of Cardiothoracic Surgery, University of Hawaii School of Medicine, Honolulu, Hawaii, USA
Ann Thorac Surg 77:942-9; discussion 949-50. 2004..We examined the safety and efficacy of a C5 complement inhibitor for attenuating inflammation-mediated cardiovascular dysfunction in cardiac surgical patients undergoing cardiopulmonary bypass... - Practice pattern variability for myocardial revascularization: impact on resource use across 24 centersJoseph S Savino
University of Pennsylvania Medical Center, Philadelphia, PA 19104 4283, USA
J Cardiothorac Vasc Anesth 16:149-56. 2002..To determine the predictors of hospital length of stay (LOS) after elective uncomplicated coronary artery bypass graft surgery... - Pulmonary-artery catheters in high-risk surgical patientsNanette M Schwann
N Engl J Med 348:2035-7; author reply 2035-7. 2003