Research Topics
| Brett A SponsellerSummaryAffiliation: Iowa State University Country: USA Publications
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Detail Information
Publications
Mechanisms of equine infectious anemia virus escape from neutralizing antibody responses define epitope specificityBrett A Sponseller
Department of Veterinary Microbiology and Preventive Medicine, Iowa State University, Ames, Iowa 50011, USA
Viral Immunol 25:324-8. 2012....
Activation of peripheral blood monocytes results in more robust production of IL-10 in neonatal foals compared to adult horsesB A Sponseller
Department of Veterinary Microbiology and Preventive Medicine, College of Veterinary Medicine, Iowa State University, Ames, IA 50011, USA
Vet Immunol Immunopathol 127:167-73. 2009....
Influenza A pandemic (H1N1) 2009 virus infection in domestic catBrett A Sponseller
College of Veterinary Medicine, Iowa State University, Ames, Iowa 50011 1248, USA
Emerg Infect Dis 16:534-7. 2010..In 2009, pandemic (H1N1) 2009 infection in a domestic cat from Iowa was diagnosed by a novel PCR assay that distinguishes between Eurasian and North American pandemic (H1N1) 2009 virus matrix genes. Human-to-cat transmission is presumed...
Syringohydromyelia in horses: 3 casesBrett A Sponseller
Department of Veterinary Clinical Sciences, College of Veterinary Medicine, Iowa State University, Ames, Iowa 50011, USA
Can Vet J 52:147-52. 2011..These lesions are not frequently reported in large animal species. The presenting complaints, clinical, gross pathological, and histopathologic findings of 2 cases of syringomyelia and 1 case of hydromyelia in horses are described...
Baseline plasma cortisol and ACTH concentrations and response to low-dose ACTH stimulation testing in ill foalsDavid M Wong
Department of Veterinary Clinical Sciences, Iowa State University, Ames, IA 50011, USA
J Am Vet Med Assoc 234:126-32. 2009..To evaluate baseline plasma cortisol and ACTH concentrations and responses to low-dose ACTH stimulation testing in ill foals...
Alloimmune neonatal neutropenia and neonatal isoerythrolysis in a Thoroughbred coltDavid M Wong
Lloyd Veterinary Medical Center, Department of Veterinary Clinical Sciences, College of Veterinary Medicine, Iowa State University, Ames, IA 50011, USA
J Vet Diagn Invest 24:219-26. 2012..Alloimmune neonatal neutropenia can be treated with prophylactic antimicrobials combined with rhG-CSF with a favorable outcome...
Agreement between arterial partial pressure of carbon dioxide and saturation of hemoglobin with oxygen values obtained by direct arterial blood measurements versus noninvasive methods in conscious healthy and ill foalsDavid M Wong
Lloyd Veterinary Medical Center, Department of Veterinary Clinical Sciences, College of Veterinary Medicine, Iowa State University, Ames, IA 50011, USA
J Am Vet Med Assoc 239:1341-7. 2011....
Immune selection of equine infectious anemia virus env variants during the long-term inapparent stage of diseaseBrett A Sponseller
Department of Veterinary Microbiology and Preventive Medicine, College of Veterinary Medicine, Iowa State University, Ames, IA 50011, USA
Virology 363:156-65. 2007..These findings indicate that neutralizing antibody exerts selective pressure throughout infection and suggest that viral strategies of immune evasion and persistence change in the face of an evolving and maturing host immune response...
Adrenocorticotropic hormone stimulation tests in healthy foals from birth to 12 weeks of ageDavid M Wong
Department of Veterinary Clinical Sciences, College of Veterinary Medicine, Iowa State University, Ames, Iowa 50011, USA
Can J Vet Res 73:65-72. 2009..These data should serve as a reference for the ACTH stimulation test in foals and should be useful in subsequent studies to evaluate the hypothalamic-pituitary-adrenal axis in healthy and critically ill foals...
Cell-mediated immunity evaluation in foals infected with virulent equine herpesvirus-1 by multi-parameter flow cytometryRatree Platt
Department of Veterinary Microbiology and Preventive Medicine, Iowa State University, Ames, IA 50011, United States
Vet Immunol Immunopathol 135:275-81. 2010..This system can be applied to measure CMI responses to other equine vaccines and pathogens...
What is your diagnosis? Chronic juvenile ossifying fibromaBrett A Sponseller
Department of Veterinary Clinical Sciences, College of Veterinary Medicine, Iowa State University, Ames, IA 50011 1250, USA
J Am Vet Med Assoc 229:1727-8. 2006
Genetic and biological variation in equine infectious anemia virus Rev correlates with variable stages of clinical disease in an experimentally infected ponyM Belshan
Department of Veterinary Microbiology and Preventive Medicine, Iowa State University, Ames, Iowa, 50011, USA
Virology 279:185-200. 2001..Statistical correlation was found between Rev activity and different stages of clinical disease. Together, these results suggest that genetic and biological variation in rev may be a contributing factor in EIAV disease progression...
