Deepak Reyon

Summary

Affiliation: Iowa State University
Country: USA

Publications

  1. pmc Predicting success of oligomerized pool engineering (OPEN) for zinc finger target site sequences
    Jeffry D Sander
    Molecular Pathology Unit, Center for Cancer Research, and Center for Computational and Integrative Biology, Massachusetts General Hospital, Charlestown, MA 02129, USA
    BMC Bioinformatics 11:543. 2010
  2. pmc ZFNGenome: a comprehensive resource for locating zinc finger nuclease target sites in model organisms
    Deepak Reyon
    Department of Genetics, Iowa State University, Ames, IA 50011, USA
    BMC Genomics 12:83. 2011
  3. pmc High frequency targeted mutagenesis in Arabidopsis thaliana using zinc finger nucleases
    Feng Zhang
    Department of Genetics, Cell Biology, and Development and Center for Genome Engineering, University of Minnesota, Minneapolis, MN 55455, USA
    Proc Natl Acad Sci U S A 107:12028-33. 2010
  4. pmc In silico abstraction of zinc finger nuclease cleavage profiles reveals an expanded landscape of off-target sites
    Jeffry D Sander
    Molecular Pathology Unit, Center for Cancer Research, Massachusetts General Hospital, Charlestown, MA 02129, USA, Center for Computational and Integrative Biology, Massachusetts General Hospital, Charlestown, MA 02129, USA, Department of Pathology, Harvard Medical School, Boston, MA 02115, USA, Program in Biological and Biomedical Sciences, Harvard Medical School, Boston, MA 02115, USA, Department of Chemistry and Chemical Biology, Harvard University, Cambridge, MA 01238, USA, Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA and Howard Hughes Medical Institute, Chevy Chase, MD 02815, USA
    Nucleic Acids Res 41:e181. 2013

Detail Information

Publications4

  1. pmc Predicting success of oligomerized pool engineering (OPEN) for zinc finger target site sequences
    Jeffry D Sander
    Molecular Pathology Unit, Center for Cancer Research, and Center for Computational and Integrative Biology, Massachusetts General Hospital, Charlestown, MA 02129, USA
    BMC Bioinformatics 11:543. 2010
    ..Because generation of ZFPs using OPEN requires considerable effort, a computational method for identifying the sites in any given gene that are most likely to be successfully targeted by this method is desirable...
  2. pmc ZFNGenome: a comprehensive resource for locating zinc finger nuclease target sites in model organisms
    Deepak Reyon
    Department of Genetics, Iowa State University, Ames, IA 50011, USA
    BMC Genomics 12:83. 2011
    ....
  3. pmc High frequency targeted mutagenesis in Arabidopsis thaliana using zinc finger nucleases
    Feng Zhang
    Department of Genetics, Cell Biology, and Development and Center for Genome Engineering, University of Minnesota, Minneapolis, MN 55455, USA
    Proc Natl Acad Sci U S A 107:12028-33. 2010
    ..Taken together, our results suggest that it should now be possible to obtain mutations in any Arabidopsis target gene regardless of its mutant phenotype...
  4. pmc In silico abstraction of zinc finger nuclease cleavage profiles reveals an expanded landscape of off-target sites
    Jeffry D Sander
    Molecular Pathology Unit, Center for Cancer Research, Massachusetts General Hospital, Charlestown, MA 02129, USA, Center for Computational and Integrative Biology, Massachusetts General Hospital, Charlestown, MA 02129, USA, Department of Pathology, Harvard Medical School, Boston, MA 02115, USA, Program in Biological and Biomedical Sciences, Harvard Medical School, Boston, MA 02115, USA, Department of Chemistry and Chemical Biology, Harvard University, Cambridge, MA 01238, USA, Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA and Howard Hughes Medical Institute, Chevy Chase, MD 02815, USA
    Nucleic Acids Res 41:e181. 2013
    ..Our improved method should enable more comprehensive profiling of ZFN specificities. ..