Tanja Opriessnig

Summary

Affiliation: Iowa State University
Country: USA

Publications

  1. ncbi Porcine circovirus type 2 associated disease: update on current terminology, clinical manifestations, pathogenesis, diagnosis, and intervention strategies
    Tanja Opriessnig
    Department of Veterinary Diagnostic and Production Animal Medicine, College of Veterinary Medicine, Iowa State University, Ames, IA 50011, USA
    J Vet Diagn Invest 19:591-615. 2007
  2. ncbi Erysipelothrix rhusiopathiae Isolates Recovered from Fish, a Harbour Seal (Phoca vitulina) and the Marine Environment are Capable of Inducing Characteristic Cutaneous Lesions in Pigs
    T Opriessnig
    Department of Veterinary Diagnostic and Production Animal Medicine, College of Veterinary Medicine, Iowa State University, Ames, IA 50011, USA Electronic address
    J Comp Pathol 148:365-72. 2013
  3. ncbi Emergence of a novel mutant PCV2b variant associated with clinical PCVAD in two vaccinated pig farms in the U.S. concurrently infected with PPV2
    Tanja Opriessnig
    Department of Veterinary Diagnostic and Production Animal Medicine, College of Veterinary Medicine, Iowa State University, Ames, IA, USA
    Vet Microbiol 163:177-83. 2013
  4. ncbi Evaluation of diagnostic assays for the serological detection of Actinobacillus pleuropneumoniae on samples of known or unknown exposure
    Tanja Opriessnig
    Department of Veterinary Diagnostic and Production Animal Medicine, College of Veterinary Medicine, Iowa State University, Ames, IA, USA
    J Vet Diagn Invest 25:61-71. 2013
  5. ncbi Current state of knowledge on porcine circovirus type 2-associated lesions
    T Opriessnig
    Department of Veterinary Diagnostic and Production Animal Medicine, College of Veterinary Medicine, Iowa State University, Ames, Iowa 50011, USA
    Vet Pathol 50:23-38. 2013
  6. ncbi Effect of porcine circovirus type 2a or 2b on infection kinetics and pathogenicity of two genetically divergent strains of porcine reproductive and respiratory syndrome virus in the conventional pig model
    Tanja Opriessnig
    Department of Veterinary Diagnostic and Production Animal Medicine, College of Veterinary Medicine, Iowa State University, Ames, IA 50011, USA
    Vet Microbiol 158:69-81. 2012
  7. ncbi A PCV2 vaccine based on genotype 2b is more effective than a 2a-based vaccine to protect against PCV2b or combined PCV2a/2b viremia in pigs with concurrent PCV2, PRRSV and PPV infection
    Tanja Opriessnig
    Department of Veterinary Diagnostic and Production Animal Medicine, College of Veterinary Medicine, Iowa State University, Ames, IA, USA
    Vaccine 31:487-94. 2013
  8. ncbi Concurrent infections are important for expression of porcine circovirus associated disease
    Tanja Opriessnig
    Department of Veterinary Diagnostic and Production Animal Medicine, College of Veterinary Medicine, Iowa State University, Ames, IA 50010, USA
    Virus Res 164:20-32. 2012
  9. ncbi An experimental live chimeric porcine circovirus 1-2a vaccine decreases porcine circovirus 2b viremia when administered intramuscularly or orally in a porcine circovirus 2b and porcine reproductive and respiratory syndrome virus dual-challenge model
    Tanja Opriessnig
    Department of Veterinary Diagnostic and Production Animal Medicine, College of Veterinary Medicine, Iowa State University, Ames, Iowa 50011, USA
    Microbiol Immunol 55:863-73. 2011
  10. ncbi Polymicrobial respiratory disease in pigs
    T Opriessnig
    Department of Veterinary Diagnostic and Production Animal Medicine, College of Veterinary Medicine, Iowa State University, Ames, USA
    Anim Health Res Rev 12:133-48. 2011

Collaborators

Detail Information

Publications57

  1. ncbi Porcine circovirus type 2 associated disease: update on current terminology, clinical manifestations, pathogenesis, diagnosis, and intervention strategies
    Tanja Opriessnig
    Department of Veterinary Diagnostic and Production Animal Medicine, College of Veterinary Medicine, Iowa State University, Ames, IA 50011, USA
    J Vet Diagn Invest 19:591-615. 2007
    ..This article is intended to discuss the most common disease manifestations, pathogenesis, diagnostic approaches, and intervention strategies associated with PCVAD in North America...
  2. ncbi Erysipelothrix rhusiopathiae Isolates Recovered from Fish, a Harbour Seal (Phoca vitulina) and the Marine Environment are Capable of Inducing Characteristic Cutaneous Lesions in Pigs
    T Opriessnig
    Department of Veterinary Diagnostic and Production Animal Medicine, College of Veterinary Medicine, Iowa State University, Ames, IA 50011, USA Electronic address
    J Comp Pathol 148:365-72. 2013
    ..infection. The results of this study indicate that the marine E. rhusiopathiae isolates have greater genetic and antigenic diversity than pig isolates and are capable of inducing classical skin lesions in pigs...
  3. ncbi Emergence of a novel mutant PCV2b variant associated with clinical PCVAD in two vaccinated pig farms in the U.S. concurrently infected with PPV2
    Tanja Opriessnig
    Department of Veterinary Diagnostic and Production Animal Medicine, College of Veterinary Medicine, Iowa State University, Ames, IA, USA
    Vet Microbiol 163:177-83. 2013
    ..In addition, emerging porcine parvovirus type 2 (PPV2) was detected in 55% of the serum samples (73/132), perhaps implying that PPV2 could be a cofactor in cases of PCVAD...
  4. ncbi Evaluation of diagnostic assays for the serological detection of Actinobacillus pleuropneumoniae on samples of known or unknown exposure
    Tanja Opriessnig
    Department of Veterinary Diagnostic and Production Animal Medicine, College of Veterinary Medicine, Iowa State University, Ames, IA, USA
    J Vet Diagn Invest 25:61-71. 2013
    ..pleuropneumoniae exposure, differences in assay targets complicate test choices. Decisions on which assay or combination of assays to use depend on the specific reasons for running the assays...
  5. ncbi Current state of knowledge on porcine circovirus type 2-associated lesions
    T Opriessnig
    Department of Veterinary Diagnostic and Production Animal Medicine, College of Veterinary Medicine, Iowa State University, Ames, Iowa 50011, USA
    Vet Pathol 50:23-38. 2013
    ..It is now widely accepted that PCV2 can be further subdivided into different types, of which PCV2a and PCV2b are present worldwide and of greatest importance. This review will focus on PCV2-associated lesions in different organ systems...
  6. ncbi Effect of porcine circovirus type 2a or 2b on infection kinetics and pathogenicity of two genetically divergent strains of porcine reproductive and respiratory syndrome virus in the conventional pig model
    Tanja Opriessnig
    Department of Veterinary Diagnostic and Production Animal Medicine, College of Veterinary Medicine, Iowa State University, Ames, IA 50011, USA
    Vet Microbiol 158:69-81. 2012
    ..This work further emphasizes in vivo replication differences among PRRSV strains and the importance of coinfecting pathogens...
  7. ncbi A PCV2 vaccine based on genotype 2b is more effective than a 2a-based vaccine to protect against PCV2b or combined PCV2a/2b viremia in pigs with concurrent PCV2, PRRSV and PPV infection
    Tanja Opriessnig
    Department of Veterinary Diagnostic and Production Animal Medicine, College of Veterinary Medicine, Iowa State University, Ames, IA, USA
    Vaccine 31:487-94. 2013
    ....
  8. ncbi Concurrent infections are important for expression of porcine circovirus associated disease
    Tanja Opriessnig
    Department of Veterinary Diagnostic and Production Animal Medicine, College of Veterinary Medicine, Iowa State University, Ames, IA 50010, USA
    Virus Res 164:20-32. 2012
    ....
  9. ncbi An experimental live chimeric porcine circovirus 1-2a vaccine decreases porcine circovirus 2b viremia when administered intramuscularly or orally in a porcine circovirus 2b and porcine reproductive and respiratory syndrome virus dual-challenge model
    Tanja Opriessnig
    Department of Veterinary Diagnostic and Production Animal Medicine, College of Veterinary Medicine, Iowa State University, Ames, Iowa 50011, USA
    Microbiol Immunol 55:863-73. 2011
    ..Under the conditions of this study, the live attenuated PCV1-2a vaccine was safe and provided immune protection resulting in reduction of viremia. The IM route provided the most effective protection...
  10. ncbi Polymicrobial respiratory disease in pigs
    T Opriessnig
    Department of Veterinary Diagnostic and Production Animal Medicine, College of Veterinary Medicine, Iowa State University, Ames, USA
    Anim Health Res Rev 12:133-48. 2011
    ..This review discusses the latest findings on polymicrobial respiratory disease in pigs...
  11. ncbi Comparison of the effectiveness of passive (dam) versus active (piglet) immunization against porcine circovirus type 2 (PCV2) and impact of passively derived PCV2 vaccine-induced immunity on vaccination
    Tanja Opriessnig
    Department of Veterinary Diagnostic and Production Animal Medicine, College of Veterinary Medicine, Iowa State University, Ames, IA 50011, USA
    Vet Microbiol 142:177-83. 2010
    ....
  12. ncbi Development and validation of an immunohistochemical method for rapid diagnosis of swine erysipelas in formalin-fixed, paraffin-embedded tissue samples
    Tanja Opriessnig
    Veterinary Diagnostic and Production Animal Medicine, College of Veterinary Medicine, Iowa State University, Ames, IA 50011, USA
    J Vet Diagn Invest 22:86-90. 2010
    ..In addition, the IHC was found to be useful for detection of E. rhusiopathiae antigen in skin lesions, which are often culture negative...
  13. ncbi Porcine circovirus type 2 (PCV2)-infection and re-inoculation with homologous or heterologous strains: virological, serological, pathological and clinical effects in growing pigs
    Tanja Opriessnig
    Department of Veterinary Diagnostic and Production Animal Medicine, College of Veterinary Medicine, Iowa State University, Ames, Iowa 50011, USA
    Vet Res 41:31. 2010
    ..In the current study, pigs had extended viremia combined with detectable tissue PCV2 antigen levels despite the presence of high levels of anti-PCV2 antibody; however, no clinical disease was observed...
  14. ncbi Experimental reproduction of porcine circovirus type 2 (PCV2)-associated enteritis in pigs infected with PCV2 alone or concurrently with Lawsonia intracellularis or Salmonella typhimurium
    T Opriessnig
    Department of Veterinary Diagnostic and Production Animal Medicine, College of Veterinary Medicine, Iowa State University, Ames, Iowa, USA
    J Comp Pathol 145:261-70. 2011
    ....
  15. ncbi Porcine circovirus type 2 (PCV2) vaccination is effective in reducing disease and PCV2 shedding in semen of boars concurrently infected with PCV2 and Mycoplasma hyopneumoniae
    T Opriessnig
    Department of Veterinary Diagnostic and Production Animal Medicine, Iowa State University, Ames, Iowa, USA
    Theriogenology 76:351-60. 2011
    ..In summary, although concurrent MHYO infection did not influence PCV2 shedding patterns, coinfection of boars with PCV2 and MHYO resulted in severe clinical disease and viral shedding was significantly decreased by PCV2 vaccination...
  16. ncbi A live-attenuated chimeric porcine circovirus type 2 (PCV2) vaccine is transmitted to contact pigs but is not upregulated by concurrent infection with porcine parvovirus (PPV) and porcine reproductive and respiratory syndrome virus (PRRSV) and is efficaci
    T Opriessnig
    Department of Veterinary Diagnostic and Production Animal Medicine, College of Veterinary Medicine, Iowa State University, Ames, IA 50011, USA
    Clin Vaccine Immunol 18:1261-8. 2011
    ....
  17. ncbi Influence of maternal antibodies on efficacy of porcine circovirus type 2 (PCV2) vaccination to protect pigs from experimental infection with PCV2
    T Opriessnig
    Department of Veterinary Diagnostic and Production Animal Medicine, College of Veterinary Medicine, Iowa State University, Ames, IA 50011, USA
    Clin Vaccine Immunol 15:397-401. 2008
    ..These results indicate that vaccination with Suvaxyn PCV2 One Dose reduces viremia and prevents microscopic lesions associated with PCV2 in the presence of maternal antibodies...
  18. ncbi Limited susceptibility of three different mouse (Mus musculus) lines to Porcine circovirus-2 infection and associated lesions
    Tanja Opriessnig
    Department of Veterinary Diagnostic and Production Animal Medicine, College of Veterinary Medicine, Iowa State University, Ames, Iowa 50011, USA
    Can J Vet Res 73:81-6. 2009
    ..The results indicate the mouse model likely has limited utility to advance understanding of the pathogenesis of PCV-2 associated lesions, but mice could potentially be important in the epidemiology of PCV-2...
  19. ncbi Difference in severity of porcine circovirus type two-induced pathological lesions between Landrace and Pietrain pigs
    T Opriessnig
    Department of Veterinary Diagnostic and Production Animal Medicine, College of Veterinary Medicine, Iowa State University, Ames 50011, USA
    J Anim Sci 87:1582-90. 2009
    ..The results from this study indicate that a genetic difference exists between these 2 breeds of pigs in susceptibility to PCV2-associated lesions...
  20. ncbi Porcine circovirus type 2 infection decreases the efficacy of a modified live porcine reproductive and respiratory syndrome virus vaccine
    T Opriessnig
    Department of Veterinary Diagnostic and Production Animal Medicine, College of Veterinary Medicine, Iowa State University, Ames, IA 50011, USA
    Clin Vaccine Immunol 13:923-9. 2006
    ..001) lower average daily weight gain than did the control and the vaccinated groups. This work suggests that PCV2 infection has an adverse effect on the development of protective immunity induced by PRRSV vaccine...
  21. ncbi Genetic and experimental comparison of porcine circovirus type 2 (PCV2) isolates from cases with and without PCV2-associated lesions provides evidence for differences in virulence
    T Opriessnig
    Department of Veterinary Diagnostic and Production Animal Medicine, College of Veterinary Medicine, Iowa State University, Ames, IA 50011 1250, USA
    J Gen Virol 87:2923-32. 2006
    ..05) in pigs inoculated with PCV2-4838. The results of this study suggest that PCV2 isolates from the USA differ in virulence in an SPF pig model...
  22. ncbi Use of an experimental model to test the efficacy of planned exposure to live porcine reproductive and respiratory syndrome virus
    Tanja Opriessnig
    Department of Veterinary Diagnostic and Production Animal Medicine, College of Veterinary Medicine, Iowa State University, Ames, IA 50011, USA
    Clin Vaccine Immunol 14:1572-7. 2007
    ..Planned exposure to live PRRSV can be used as an inexpensive and effective way to decrease the severity of PRRSV-induced disease following subsequent challenge...
  23. ncbi Effect of porcine circovirus type 2 (PCV2) vaccination on porcine reproductive and respiratory syndrome virus (PRRSV) and PCV2 coinfection
    T Opriessnig
    Department of Veterinary Diagnostic and Production Animal Medicine, College of Veterinary Medicine, Iowa State University, Ames, IA 50011, USA
    Vet Microbiol 131:103-14. 2008
    ..Differences between intradermal and intramuscular routes of vaccine administration were not observed...
  24. ncbi Porcine circovirus type 2 in muscle and bone marrow is infectious and transmissible to naïve pigs by oral consumption
    Tanja Opriessnig
    Department of Veterinary Diagnostic and Production Animal Medicine, College of Veterinary Medicine, Iowa State University, 1600 South 16th Street, Ames, IA 50011, USA
    Vet Microbiol 133:54-64. 2009
    ..Results from this study indicate that uncooked PCV2 DNA positive lymphoid tissues, bone marrow, and skeletal muscle from PCV2 viremic pigs contain sufficient amount of infectious PCV2 to infect naïve pigs by the oral route...
  25. ncbi Differences in virulence among porcine circovirus type 2 isolates are unrelated to cluster type 2a or 2b and prior infection provides heterologous protection
    T Opriessnig
    Department of Veterinary Diagnostic and Production Animal Medicine, College of Veterinary Medicine, Iowa State University, Ames, IA 50011, USA
    J Gen Virol 89:2482-91. 2008
    ..Increased virulence as reported to be associated with PCV2b isolates in the field was not observed under the conditions of this study. Moreover, cross-protection between PCV2a and PCV2b exists...
  26. ncbi Comparison of efficacy of commercial one dose and two dose PCV2 vaccines using a mixed PRRSV-PCV2-SIV clinical infection model 2-3-months post vaccination
    T Opriessnig
    Department of Veterinary Diagnostic and Production Animal Medicine, College of Veterinary Medicine, Iowa State University, Ames, IA 50011, United States
    Vaccine 27:1002-7. 2009
    ..Viremia was reduced by 78.5% in pigs vaccinated with one dose and by 97.1% in pigs vaccinated with two dose products and overall microscopic lymphoid lesions were reduced by 78.7% and 81.8%, respectively...
  27. ncbi Studies on porcine circovirus type 2 vaccination of 5-day-old piglets
    K C O'Neill
    Department of Veterinary Diagnostic and Production Animal Medicine, College of Veterinary Medicine, Iowa State University, 1600 S 16th Street, Ames, IA 50011, USA
    Clin Vaccine Immunol 18:1865-71. 2011
    ....
  28. ncbi Identification and characterization of novel porcine astroviruses (PAstVs) with high prevalence and frequent co-infection of individual pigs with multiple PAstV types
    Chao Ting Xiao
    Department of Veterinary Diagnostic and Production Animal Medicine, College of Veterinary Medicine, Iowa State University, Ames, IA, USA
    J Gen Virol 94:570-82. 2013
    ..Phylogenetic analysis revealed that PAstV1, PAstV2 and PAstV3 were more closely related to AstVs from humans and other animals than to each other, indicating past cross-species transmission and the zoonotic potential of these PAstVs...
  29. ncbi Infectivity of porcine circovirus type 2 DNA in semen from experimentally-infected boars
    Darin M Madson
    Department of Veterinary Diagnostic and Production Animal Medicine, College of Veterinary Medicine, Iowa State University, Ames, Iowa, USA
    Vet Res 40:10. 2009
    ....
  30. ncbi ORF1 but not ORF2 dependent differences are important for in vitro replication of PCV2 in porcine alveolar macrophages singularly or coinfected with PRRSV
    Avanti Sinha
    Veterinary Diagnostic and Production Animal Medicine, College of Veterinary Medicine, Iowa State University, Ames, IA 50011 1250, USA
    Vet Microbiol 158:95-103. 2012
    ....
  31. ncbi Characterization of shedding patterns of Porcine circovirus types 2a and 2b in experimentally inoculated mature boars
    Darin M Madson
    Department of Veterinary Diagnostic and Production Animal Medicine, College of Veterinary Medicine, Iowa State University, Ames, IA 50011, USA
    J Vet Diagn Invest 20:725-34. 2008
    ..Differences in shedding patterns between PCV-2a and -2b were not observed under the study conditions...
  32. ncbi Expression of human CD46 has no effect on porcine circovirus type 2 infection and shedding in the experimental pig model
    Michelle Hemann
    Department of Veterinary Diagnostic and Production Animal Medicine, College of Veterinary Medicine, Iowa State University, 1600 S 16th Street, Ames, IA, 50011, USA
    Vet Res Commun 36:187-93. 2012
    ..Under the study conditions, the presence of human CD46 in transgenic pigs had no effect on PCV2 infection in otherwise healthy pigs capable of a normal immune response...
  33. ncbi Prevalence and phylogenetic analysis of the current porcine circovirus 2 genotypes after implementation of widespread vaccination programmes in the USA
    Hui Gang Shen
    Department of Veterinary Diagnostic and Production Animal Medicine, College of Veterinary Medicine, Iowa State University, Ames, Iowa, USA
    J Gen Virol 93:1345-55. 2012
    ..The data generated in this study provide novel information on the distribution of PCV2 genotypes in vaccinated pig populations...
  34. ncbi Comparison of three enzyme-linked immunosorbent assays to detect Porcine circovirus-2 (PCV-2)-specific antibodies after vaccination or inoculation of pigs with distinct PCV-1 or PCV-2 isolates
    Abby R Patterson
    Department of Veterinary Diagnostic and Production Animal Medicine, College of Veterinary Medicine, Iowa State University, Ames, IA 50011 1250, USA
    J Vet Diagn Invest 20:744-51. 2008
    ..One of the ELISAs was able to distinguish pigs vaccinated with vaccine B from pigs inoculated with either PCV-2a or PCV-2b...
  35. ncbi Novel chimeric porcine circovirus (PCV) with the capsid gene of the emerging PCV2b subtype cloned in the genomic backbone of the non-pathogenic PCV1 is attenuated in vivo and induces protective and cross-protective immunity against PCV2b and PCV2a subtype
    Nathan M Beach
    Department of Biomedical Sciences and Pathobiology, College of Veterinary Medicine, Virginia Polytechnic Institute and State University, Blacksburg, VA, United States
    Vaccine 29:221-32. 2010
    ..The results indicate the chimeric PCV1-2b virus is a good candidate for a live-attenuated vaccine against both PCV2b and PCV2a subtypes...
  36. ncbi Serological profile of torque teno sus virus species 1 (TTSuV1) in pigs and antigenic relationships between two TTSuV1 genotypes (1a and 1b), between two species (TTSuV1 and -2), and between porcine and human anelloviruses
    Yao Wei Huang
    Center for Molecular Medicine and Infectious Diseases, Department of Biomedical Sciences and Pathobiology, College of Veterinary Medicine, Virginia Polytechnic Institute and State University, Blacksburg, Virginia, USA
    J Virol 86:10628-39. 2012
    ..These results have important implications for an understanding of the diversity of anelloviruses as well as for the classification and vaccine development of TTSuVs...
  37. ncbi High prevalence of porcine circovirus viremia in newborn piglets in five clinically normal swine breeding herds in North America
    Huigang Shen
    Department of Veterinary Diagnostic and Production Animal Medicine, College of Veterinary Medicine, Iowa State University, Ames, IA 50011, USA
    Prev Vet Med 97:228-36. 2010
    ..This information adds to the knowledge of PCV2 infection in breeding herds...
  38. ncbi Cytokine and chemokine mRNA expression profiles in tracheobronchial lymph nodes from pigs singularly infected or coinfected with porcine circovirus type 2 (PCV2) and Mycoplasma hyopneumoniae (MHYO)
    Huanrong Zhang
    Department of Veterinary Diagnostic and Production Animal Medicine, College of Veterinary Medicine, Iowa State University, 1600 S 16th Street, Ames, IA 50011, USA
    Vet Immunol Immunopathol 140:152-8. 2011
    ..In summary, this work provided evidence that the increased severity of lesions in PCV2 and MHYO coinfected pigs was associated mainly with the presence of PCV2 antigen and alterations of cytokine mRNA expression profiles...
  39. ncbi The prevalence of Torque teno sus virus (TTSuV) is common and increases with the age of growing pigs in the United States
    Chao Ting Xiao
    Department of Veterinary Diagnostic and Production Animal Medicine, College of Veterinary Medicine, Iowa State University, Ames, IA, USA
    J Virol Methods 183:40-4. 2012
    ..8% and 100% in growing pigs. The results of this study indicate that vertical transmission may not be a main route of TTSuV transmission in pigs in the USA...
  40. ncbi Comparison of conventional direct and enrichment culture methods for Erysipelothrix spp. from experimentally and naturally infected swine
    Joseph S Bender
    Veterinary Diagnostic and Production Animal Medicine, College of Veterinary Medicine, Iowa State University, Ames, IA 50011, USA
    J Vet Diagn Invest 21:863-8. 2009
    ..from clinical samples with a history suggestive of erysipelas and that Vagococcus spp. is potentially an important differential diagnosis...
  41. ncbi Interlaboratory comparison of Porcine circovirus-2 indirect immunofluorescent antibody test and enzyme-linked immunosorbent assay results on experimentally infected pigs
    Abby R Patterson
    Department of Veterinary Diagnostic and Production Animal Medicine, College of Veterinary Medicine, Iowa State University, Ames, IA 50011, USA
    J Vet Diagn Invest 23:206-12. 2011
    ..94 to 1.00, 0.72 to 1.00, and 0.95 to 1.00, respectively. However, test sensitivities varied based on laboratory-specific cutoffs that were used to dichotomize test results...
  42. ncbi Genetic and phenotypic characterization of a 2006 United States porcine reproductive and respiratory virus isolate associated with high morbidity and mortality in the field
    Phillip C Gauger
    Department of Veterinary Diagnostic and Production Animal Medicine, College of Veterinary Medicine, Iowa State University, Ames, IA 50011, USA
    Virus Res 163:98-107. 2012
    ....
  43. ncbi Erysipelothrix spp. genotypes, serotypes, and surface protective antigen types associated with abattoir condemnations
    Joseph S Bender
    Veterinary Diagnostic and Production Animal Medicine, College of Veterinary Medicine, Iowa State University, Ames, IA 50011, USA
    J Vet Diagn Invest 23:139-42. 2011
    ..tonsillarum, thought to be avirulent for swine, was isolated from systemic sites from 3.4% of the carcasses that were negative for E. rhusiopathiae, indicating the potential importance of this genotype in erysipelas pathogenesis...
  44. ncbi Inhibition of porcine reproductive and respiratory syndrome virus infection in piglets by a peptide-conjugated morpholino oligomer
    Tanja Opriessnig
    Department of Veterinary Diagnostic and Production Animal Medicine, College of Veterinary Medicine, Iowa State University, Ames, USA
    Antiviral Res 91:36-42. 2011
    ..This study provides further data indicating that the 5UP2 PPMO can be considered a candidate component for a novel PRRS control strategy...
  45. ncbi Comparison of commercial real-time reverse transcription-PCR assays for reliable, early, and rapid detection of heterologous strains of porcine reproductive and respiratory syndrome virus in experimentally infected or noninfected boars by use of different
    Priscilla F Gerber
    Department of Veterinary Diagnostic and Production Animal Medicine, Iowa State University, Ames, Iowa, USA
    J Clin Microbiol 51:547-56. 2013
    ..The AB assay had a 1.6-times-shorter PCR time. In summary, serum and blood swabs had the best performance with highest detection rates and agreement between assays and the shortest turnaround times...
  46. ncbi Complete genome sequence of a newly identified porcine astrovirus genotype 3 strain US-MO123
    Chao Ting Xiao
    Department of Veterinary Diagnostic and Production Animal Medicine, College of Veterinary Medicine, Iowa State University, Ames, Iowa, USA
    J Virol 86:13126. 2012
    ..Sequence comparison and phylogenetic analysis showed that PAstV3 has the closest relationship with mink AstV and the human AstV strains VA1, VA2, and SG, indicating the same ancestral origin and zoonotic potential of the virus...
  47. ncbi Complete genome sequence of a novel porcine circovirus type 2b variant present in cases of vaccine failures in the United States
    Chao Ting Xiao
    Department of Veterinary Diagnostic and Production Animal Medicine, College of Veterinary Medicine, Iowa State University, Ames, Iowa, USA
    J Virol 86:12469. 2012
    ..The genomic knowledge of this mutant PCV2b will improve understanding of the epidemiology of PCV and potentially inform the development of new and more effective vaccines for PCV2...
  48. ncbi Establishment of a DNA-launched infectious clone for a highly pneumovirulent strain of type 2 porcine reproductive and respiratory syndrome virus: identification and in vitro and in vivo characterization of a large spontaneous deletion in the nsp2 region
    Yan Yan Ni
    Center for Molecular Medicine and Infectious Diseases, Department of Biomedical Sciences and Pathobiology, College of Veterinary Medicine, Virginia Tech, Blacksburg, VA 24061 0913, USA
    Virus Res 160:264-73. 2011
    ..The results from this study indicates that the spontaneous nsp2 deletion plays a role for enhanced PRRSV replication in vitro but has no effect on the pathogenicity of the virus...
  49. ncbi Comparison of experimental models for Streptococcus suis infection of conventional pigs
    Francisco J Pallares
    Veterinary Diagnostic Laboratory, Department of Veterinary Microbiology and Preventive Medicine, College of Veterinary Medicine, Iowa State University, Ames, Iowa 50011, USA
    Can J Vet Res 67:225-8. 2003
    ..The IN-AA model should serve as a good model for S. suis-induced disease, because the natural route of exposure is intranasal and the IN-AA model was effective in inducing disease that mimics what is observed in the field...
  50. ncbi Singular PCV2a or PCV2b infection results in apoptosis of hepatocytes in clinically affected gnotobiotic pigs
    Avanti Sinha
    Department of Veterinary Diagnostic and Production Animal Medicine, Iowa State University, Ames, IA 50011, USA
    Res Vet Sci 92:151-6. 2012
    ..This suggests that PCV2-induced apoptosis of hepatocytes is important in the pathogenesis of PCV2-associated lesions and disease...
  51. ncbi Characterization of porcine parvovirus type 2 (PPV2) which is highly prevalent in the USA
    Chao Ting Xiao
    Department of Veterinary Diagnostic and Production Animal Medicine, College of Veterinary Medicine, Iowa State University, Ames, IA, United States
    Vet Microbiol 161:325-30. 2013
    ..Phylogenetic and sequence homology analyses demonstrated a close relationship of PPV2 with members of the proposed genus PARV4-like virus, and the classification of PPV2 into this proposed genus is suggested...
  52. ncbi Rescue of a porcine anellovirus (torque teno sus virus 2) from cloned genomic DNA in pigs
    Yao Wei Huang
    Department of Biomedical Sciences and Pathobiology, College of Veterinary Medicine, Virginia Polytechnic Institute and State University Virginia Tech, Blacksburg, Virginia, USA
    J Virol 86:6042-54. 2012
    ..The availability of an infectious DNA clone of TTSuV2 will facilitate future study of porcine anellovirus pathogenesis and biology...
  53. ncbi Increasing porcine PARV4 prevalence with pig age in the U.S. pig population
    Chao Ting Xiao
    Department of Veterinary Diagnostic and Production Animal Medicine, College of Veterinary Medicine, Iowa State University, Ames, Iowa, USA
    Vet Microbiol 160:290-6. 2012
    ..To the authors' knowledge, this is the first description of porcine PARV4 in the U.S. pig population...
  54. ncbi Development of a reverse transcription-PCR assay to detect porcine circovirus type 2 transcription as a measure of replication
    Shan Yu
    Department of Veterinary Microbiology and Preventive Medicine, Veterinary Medicine, Iowa State University, Ames, IA 50011, USA
    J Virol Methods 123:109-12. 2005
    ..This assay will be useful in assessing cell populations that support PCV2 replication in vivo or in vitro and advance the understanding of PCV2 replication and pathogenesis...
  55. ncbi Systemic Conidiobolus incongruus infection and hypertrophic osteopathy in a white-tailed deer (Odocoileus virginianus)
    Darin M Madson
    Department of Veterinary Diagnostic and Production Animal Medicine, College of Veterinary Medicine, Iowa State University, Ames, IA 50011, USA
    J Vet Diagn Invest 21:167-70. 2009
    ..Furthermore, the proliferative lesions of the metatarsal bones along with the intrathoracic mass were compatible with hypertrophic osteopathy...
  56. ncbi Porcine reproductive and respiratory syndrome virus infection at the time of porcine circovirus type 2 vaccination has no impact on vaccine efficacy
    A Sinha
    Department of Veterinary Diagnostic and Production Animal Medicine, College of Veterinary Medicine, Iowa State University, Ames, IA 50011, USA
    Clin Vaccine Immunol 17:1940-5. 2010
    ..The results indicate that acute PRRSV infection at the time of PCV2 vaccination has no adverse effect on PCV2 vaccine efficacy...
  57. ncbi Peptide-conjugated morpholino oligomers inhibit porcine reproductive and respiratory syndrome virus replication
    Deendayal Patel
    Molecular Virology Laboratory, VA MD Regional College of Veterinary Medicine, University of Maryland, College Park, MD 20742, USA
    Antiviral Res 77:95-107. 2008
    ..5UP2 and 5HP inhibited virus replication of 10 other strains of PRRSV. Results from this study suggest potential applications of PPMO for PRRS control...