Research Topics
| Annette M O'ConnorSummaryAffiliation: Iowa State University Country: USA Publications
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Detail Information
Publications
Robust Bayesian prediction of subject disease status and population prevalence using several similar diagnostic testsRichard B Evans
Production Animal Medicine, College of Veterinary Medicine, Iowa State University, Ames, Iowa, USA
Stat Med 23:2227-36. 2004..The amount of downweighting depends on the degree of conflict among the test results for the subject...
Chlorine: state of the artRichard B Evans
Cayuga Medical Center, Ithaca, NY 14850, USA
Lung 183:151-67. 2005....
Statistics and evidence-based veterinary medicine: answers to 21 common statistical questions that arise from reading scientific manuscriptsRichard B Evans
Veterinary Diagnostic and Production Animal Medicine, Iowa State University College of Veterinary Medicine, Ames, IA 50011, USA
Vet Clin North Am Small Anim Pract 37:477-86. 2007..This article is designed to assist veterinarians with the interpretation and understanding of statistics presented in papers...
Critically appraising studies reporting assessing diagnostic testsAnnette O'Connor
Veterinary Diagnostic and Production Animal Medicine, Iowa State University College of Veterinary Medicine, Ames, IA 50011, USA
Vet Clin North Am Small Anim Pract 37:487-97. 2007..The article also contains a glossary of terms that are useful in discussions about diagnostic tests...
A mixed treatment comparison meta-analysis of antibiotic treatments for bovine respiratory diseaseAnnette M O'Connor
Department of Veterinary Diagnostics and Production Animal Medicine, Iowa State University College of Veterinary Medicine, 1600 South 16th Street, Ames, IA 50011, United States Electronic address
Prev Vet Med 110:77-87. 2013..The output also included a relative ranking of the treatments and estimates of the probability that an antibiotic protocol was the worst treatment option...
An evaluation of the prevalence of Bovine herpesvirus 1 abortions based on diagnostic submissions to five U.S.-based veterinary diagnostic laboratoriesStacie Gould
College of Veterinary Medicine, Iowa State University, Ames, IA 50010, USA
J Vet Diagn Invest 25:243-7. 2013..It was found that using a χ(2) test, a P value of 0.068 for nonmatched data (i.e., a history of vaccination against BoHV-1 in the herd) was associated with reduced detection of BoHV-1-positive abortion submissions...
Process mapping the prevalence of Salmonella contamination on pork carcass from slaughter to chilling: a systematic review approachAnnette M O'Connor
Department of Veterinary Diagnostics and Production Animal Medicine, College of Veterinary Medicine, Iowa State University, Ames, IA 50011, USA
Foodborne Pathog Dis 9:386-95. 2012..These findings suggest that the processing procedures in place generally result in decreased prevalence of Salmonella spp. as the carcasses move toward the cooler...
A randomized clinical trial evaluating a farm-of-origin autogenous Moraxella bovis vaccine to control infectious bovine keratoconjunctivis (pinkeye) in beef cattleA M O'Connor
Department of Veterinary Diagnostics and Production Animal Medicine, Iowa State University College of Veterinary Medicine, Ames, IA 50011, USA
J Vet Intern Med 25:1447-53. 2011..A randomized, masked, 2-arm parallel trial was conducted to assess the efficacy of a Moraxella bovis (M. bovis) autogenous vaccine to prevent naturally occurring infectious bovine keratoconjunctivis (IBK) in beef calves...
Descriptive epidemiology of Moraxella bovis, Moraxella bovoculi and Moraxella ovis in beef calves with naturally occurring infectious bovine keratoconjunctivitis (Pinkeye)A M O'Connor
Department of Veterinary Diagnostics and Production Animal Medicine, Iowa State University College of Veterinary Medicine, 1600 S 16th St, Ames, IA 50011, USA
Vet Microbiol 155:374-80. 2012..Infectious bovine keratoconjunctivitis (IBK) is an ocular disease that causes substantial weight loss in beef calves...
A review of randomized clinical trials reporting antibiotic treatment of infectious bovine keratoconjunctivitis in cattleAnnette M O'Connor
Veterinary Diagnostic and Production Animal Medicine, College of Veterinary Medicine, Iowa State University, Ames, IA 50010, USA
Anim Health Res Rev 7:119-27. 2006..This review demonstrates the need for further randomized controlled trials that evaluate the efficacy of antibiotic treatment for IBK, including direct comparisons of two or more antibiotics...
Feeding management practices and feed characteristics associated with Salmonella prevalence in live and slaughtered market-weight finisher swine: a systematic review and summation of evidence from 1950 to 2005A M O'Connor
Department of Veterinary Diagnostic and Production Animal Medicine, College of Veterinary Medicine, Iowa State University, South 16th Street, Ames, IA 50010, USA
Prev Vet Med 87:213-28. 2008..There is no strong evidence regarding associations between presence of Salmonella and the other feed characteristics examined...
The REFLECT statement: methods and processes of creating reporting guidelines for randomized controlled trials for livestock and food safetyA M O'Connor
Vet Diagnostic and Production Animal Medicine, Veterinary Medicine Research Institute Building 4, Iowa State University, Ames, IA 50011, USA
Prev Vet Med 93:11-8. 2010..The use of the REFLECT statement, which addresses issues unique to livestock trials, should improve the quality of reporting and design for trials reporting production, health, and food-safety outcomes...
The REFLECT statement: methods and processes of creating reporting guidelines for randomized controlled trials for livestock and food safetyA M O'Connor
Vet Diagnostic and Production Animal Medicine, Veterinary Medicine Research Institute Building 4, Iowa State University, Ames, IA 50011, USA
J Vet Intern Med 24:57-64. 2010..The use of the REFLECT statement, which addresses issues unique to livestock trials, should improve the quality of reporting and design for trials reporting production, health, and food-safety outcomes...
Quantity and distribution of Salmonella recovered from three swine lairage pensA M O'Connor
Department of Veterinary Diagnostic and Production Animal Medicine, College of Veterinary Medicine, Iowa State University, Ames, Iowa 50010, USA
J Food Prot 69:1717-9. 2006..However, this variation suggests that numeroussamples are required to adequately describe the concentration of Salmonella in a lairage pen...
The REFLECT statement: methods and processes of creating reporting guidelines for randomized controlled trials for livestock and food safetyA M O'Connor
Vet Diagnostic and Production Animal Med, Veterinary Medicine Research Institute Building 4, Iowa State University, Ames, IA 50011, USA
J Food Prot 73:132-9. 2010..The use of the REFLECT statement, which addresses issues unique to livestock trials, should improve the quality of reporting and design for trials reporting production, health, and food-safety outcomes...
The REFLECT statement: methods and processes of creating reporting guidelines for randomized controlled trials for livestock and food safety by modifying the CONSORT statementA M O'Connor
Veterinary Diagnostic and Production Animal Med, Veterinary Medicine Research Institute Building 4, Iowa State University, Ames, IA 50011, USA
Zoonoses Public Health 57:95-104. 2010..The use of the REFLECT statement, which addresses issues unique to livestock trials, should improve the quality of reporting and design for trials reporting production, health and food-safety outcomes...
The association between proximity to animal feeding operations and community health: a systematic reviewAnnette M O'Connor
Department of Veterinary Diagnostic and Production Animal Medicine, College of Veterinary Medicine, Iowa State University, Ames, Iowa, United States of America
PLoS ONE 5:e9530. 2010..A systematic review was conducted for the association between animal feeding operations (AFOs) and the health of individuals living near AFOs...
The relationship between the occurrence of undifferentiated bovine respiratory disease and titer changes to bovine coronavirus and bovine viral diarrhea virus in 3 Ontario feedlotsA O'Connor
Department of Population Medicine, University of Guelph, Ontario
Can J Vet Res 65:137-42. 2001..Based on our findings we infer that BCV was not causally related to UBRD occurrence, however consistent with other literature, BVDV may be causally related to UBRD occurrence...
Characteristics of clinical trials assessing antimicrobial treatment of bovine respiratory disease, 1970-2005Annette M O'Connor
Department of Veterinary Diagnostic and Production Animal Medicine, College of Veterinary Medicine, Iowa State University, Ames, IA 50010, USA
J Am Vet Med Assoc 237:701-5. 2010..To evaluate reporting of key study design features and study outcomes in trials of antimicrobial treatment of bovine respiratory disease (BRD) in North American feedlots...
Reporting guidelines for primary research: Saying what you didAnnette O'Connor
Department of Veterinary Diagnostic and Production Animal Medicine, College of Veterinary Medicine, Iowa State University, USA
Prev Vet Med 97:144-9. 2010..Guidelines can be used by authors, reviewers and editors to provide readers with a full and accurate description of the work conducted...
The relationship between the occurrence of undifferentiated bovine respiratory disease and titer changes to Haemophilus somnus and Mannheimia haemolytica at 3 Ontario feedlotsA O'Connor
Department of Population Medicine, University of Guelph, Ontario
Can J Vet Res 65:143-50. 2001..somnus exposure in the unvaccinated group. The association between titer change to H. somnus and UBRD occurrence seen in this study may be a consequence of prolonged exposure to antibiotics, rather than a causal association...
Changes in the prevalence of resistant Escherichia coil in cattle receiving subcutaneously injectable oxytetracycline in addition to in-feed chlortetracycline compared with cattle receiving only in-feed chlortetracyclineA M O'Connor
Can J Vet Res 66:145-50. 2002..The use of injectable oxytetracycline in addition to in-feed chlortetracycline was significantly associated (P < 0.05) with an increase in the prevalence of resistance only to chloramphenicol and sulfisoxazole...
Sub-iliac lymph nodes at slaughter lack ability to predict Salmonella enterica prevalence for swine farmsBing Wang
Department of Veterinary Diagnostic and Production Animal Medicine, College of Veterinary Medicine, Iowa State University, Ames, Iowa 50011, USA
Foodborne Pathog Dis 7:795-800. 2010..The low detection rate of Salmonella in sub-iliac lymph nodes (0.06%) limits its usefulness as a dependable predictor of Salmonella contamination originating on farm (3.4%)...
Salmonella enterica in swine production: assessing the association between amplified fragment length polymorphism and epidemiological units of concernBing Wang
Department of Veterinary Diagnostic and Production Animal Medicine, College of Veterinary Medicine, Iowa State University, Ames, IA 50011, USA
Appl Environ Microbiol 77:8080-7. 2011..Therefore, among the three subtyping methods, serotyping, MLST, and AFLP, AFLP was the method that was able to differentiate among Salmonella isolates from different farms and link contamination at the abattoir to the farm of origin...
Efficacy of vaccination to reduce Salmonella prevalence in live and slaughtered swine: a systematic review of literature from 1979 to 2007Thomas N Denagamage
Department of Veterinary Diagnostic and Production Animal Medicine, College of Veterinary Medicine, Iowa State University, Ames, Iowa 50011 1250, USA
Foodborne Pathog Dis 4:539-49. 2007....
Seroprevalence of Anaplasma marginale in 2 Iowa feedlots and its association with morbidity, mortality, production parameters, and carcass traitsJohann F Coetzee
Department of Veterinary Diagnostic and Production Animal Medicine, College of Veterinary Medicine, Iowa State University, Ames, Iowa 50011, USA
Can Vet J 51:862-8. 2010..17). Although prevalence of anaplasmosis in Iowa feedlots is higher than reported in Montana-sourced calves arriving in Canadian feedlots, this was not associated with increased production costs...
The association between cleaning and disinfection of lairage pens and the prevalence of Salmonella enterica in swine at harvestPeggy L Schmidt
College of Veterinary Medicine, Iowa State University, Ames, Iowa 50011, USA
J Food Prot 67:1384-8. 2004..enterica in lairage pens, but the ability of cleaned and disinfected pens to reduce the prevalence of S. enterica in market-weight pigs remains inconclusive...
Identifying questions in the American Association of Swine Veterinarian's PRRS risk assessment survey that are important for retrospectively classifying swine herds according to whether they reported clinical PRRS outbreaks in the previous 3 yearsDerald J Holtkamp
Department of Veterinary Diagnostic and Production Animal Medicine, College of Veterinary Medicine, Iowa State University, Ames, IA 50011, USA
Prev Vet Med 106:42-52. 2012..Sections with a high percentage of questions identified as unimportant included (1) characteristics of the site, (2) disposal of dead animals and waste management and (3) employee and visitors...
Reporting of methodological features in observational studies of pre-harvest food safetyJan M Sargeant
Centre for Public Health and Zoonoses, University of Guelph, Guelph, Ontario, Canada
Prev Vet Med 98:88-98. 2011..Improvement in reporting of observational studies of pre-harvest food safety will aid research readers and reviewers in interpreting and evaluating the results of such studies...
Assessing the effect of sample handling on the performance of a commercial bovine viral diarrhea virus antigen-capture enzyme-linked immunosorbent assayMatthew C Reed
College of Veterinary Medicine, Iowa State University, Ames, IA 50010, USA
J Vet Diagn Invest 20:124-6. 2008..No difference in test results was found between the 3 ear-notcher treatment groups. The sample handling practices evaluated appeared to have little impact on test sensitivity or specificity of ACE for BVDV...
Differential expression of sheep beta-defensin-1 and -2 and interleukin 8 during acute Mannheimia haemolytica pneumoniaMark R Ackermann
Department of Veterinary Pathology, College of Veterinary Medicine, 2738 Veterinary Medicine, Iowa State University, Ames, IA 50011 1250, USA
Microb Pathog 37:21-7. 2004..This study suggests that SDB-1 expression occurs in epithelia and decreases during severe bacterial pneumonia, which is in contrast to the increase that occurs with PI-3 infection...
Developmental expression and distribution of sheep beta-defensin-2David K Meyerholz
Department of Veterinary Pathology, 2740 Veterinary Medicine, Iowa State University, Ames, IA 50011 1250, USA
Dev Comp Immunol 28:171-8. 2004..Interestingly, ileal follicle-associated epithelium lacked detectable SBD-2 immunoreactivity. SBD-2 mRNA and peptide expression are greatest in the intestinal tract and tissue distribution progressively decreases with maturity...
Enhanced surfactant protein and defensin mRNA levels and reduced viral replication during parainfluenza virus type 3 pneumonia in neonatal lambsBranka Grubor
Department of Veterinary Pathology, 2740 Veterinary Medicine, Iowa State University, Ames, IA 50011 1250, USA
Clin Diagn Lab Immunol 11:599-607. 2004....
Induction of differential immune reactivity to members of the flora of gnotobiotic mice following colonization with Helicobacter bilis or Brachyspira hyodysenteriaeAlbert E Jergens
Department of Veterinary Microbiology and Preventive Medicine, College of Veterinary Medicine, Iowa State University, Ames, IA 50011, USA
Microbes Infect 8:1602-10. 2006..These results indicate that microbial perturbation may induce differential immune responses to nonpathogenic resident bacteria that can lead to intestinal inflammation...
Helicobacter bilis triggers persistent immune reactivity to antigens derived from the commensal bacteria in gnotobiotic C3H/HeN miceAlbert E Jergens
Department of Veterinary Clinical Sciences, College of Veterinary Medicine, Iowa State University, Ames, IA 50011, USA
Gut 56:934-40. 2007..However, consensus regarding the role of Helicobacter as a model organism to study microbial-induced IBD is confounded by the presence of a complex colonic microbiota...
The quality of reporting and publication status of vaccines trials presented at veterinary conferences from 1988 to 2003Samantha Brace
Department of Veterinary Diagnostic and Production Animal Medicine, College of Veterinary Medicine, Iowa State University, Ames, IA 50010, USA
Vaccine 28:5306-14. 2010..For many conference proceedings it would be difficult to assess the internal and external validity of the trial based on the information reported...
Detection of Porcine reproductive and respiratory syndrome virus infection in porcine oral fluid samples: a longitudinal study under experimental conditionsJohn Prickett
Department of Veterinary Diagnostic and Production Animal Medicine, College of Veterinary Medicine, Iowa State University, Ames, IA 50011 1250, USA
J Vet Diagn Invest 20:156-63. 2008..Although the approach remains to be validated in the field, the results of this experiment suggest that pen-based oral fluid sampling could be an efficient, cost-effective approach to PRRSV surveillance in swine populations...
Characterization of the carrier state in porcine reproductive and respiratory syndrome virus infectionDennis C Horter
Department of Veterinary Microbiology and Preventive Medicine, College of Veterinary Medicine, Iowa State University, Ames, IA 50011, USA
Vet Microbiol 86:213-28. 2002..RT-nPCR is a useful tool for detection of carriers, but diagnostic sample selection is critical if false negative results are to be avoided...
The economics of pain managementHeather P Newton
Department of Veterinary Diagnositic and Production Animal Medicine, Iowa State University College of Veterinary Medicine, Ames, IA 50010, USA
Vet Clin North Am Food Anim Pract 29:229-50. 2013..This is a concern because survey data suggest producers are partly motivated based on economic factors. The unanswered question is whether economic incentive programs would be greater motivators than increased production...
Where are the food animal veterinarian shortage areas anyway?Tong Wang
Department of Economics, 260 Heady Hall, Iowa State University, Ames, IA 50011 1070, United States
Prev Vet Med 104:198-206. 2012..Comparative shortage is generally more severe in states that have no VMLRP designated private practice shortage counties than in states that do...
Monoclonal antibody analysis of porcine reproductive and respiratory syndrome virus epitopes associated with antibody-dependent enhancement and neutralization of virus infectionSol M Cancel-Tirado
Departments of Veterinary Microbiology and Preventive Medicine, College of Veterinary Medicine, Iowa State University, Ames, IA 50011, USA
Vet Immunol Immunopathol 102:249-62. 2004....
The myth of informed consent in rectal cancer surgery: what do patients retain?Adena S Scheer
Department of Surgery, The Ottawa Hospital, Ottawa, Ontario, Canada
Dis Colon Rectum 55:970-5. 2012..Previous research in colorectal cancer has focused on survival, recurrence, and functional outcomes. Few have assessed the decisional needs of patients or the information patients are retaining from the informed consent process...
Intestinal cytokine mRNA expression in canine inflammatory bowel disease: a meta-analysis with critical appraisalAlbert E Jergens
Department of Veterinary Clinical Sciences, Iowa State University, Ames, Iowa, USA
Comp Med 59:153-62. 2009..Heterogeneity of results among these studies might be explained by numerous factors including the method of mRNA quantification, stage of disease, and demographic differences in study populations...
Comparison of tibial plateau angle between clinically normal Greyhounds and Labrador Retrievers with and without rupture of the cranial cruciate ligamentVicki L Wilke
Department of Veterinary Clinical Sciences, College of Veterinary Medicine, Iowa State University, Ames, IA 50011-1250, USA
J Am Vet Med Assoc 221:1426-9. 2002..Because Greyhounds and unaffected Labrador Retrievers had similar standing TPAs, we conclude that although TPA may be associated with damage to the cruciate ligaments, many dogs with a steep TPA do not develop cruciate ligament disease...
Single-case experimental designs in veterinary researchRichard B Evans
Orthopaedic Research Laboratory, College of Veterinary Medicine, Iowa State University, Ames, IA 50011, USA
Am J Vet Res 67:189-95. 2006
Serum cortisol concentration and force plate analysis in the assessment of pain associated with sodium urate-induced acute synovitis in dogsJudith D Feldsein
Department of Veterinary Clinical Sciences, College of Veterinary Medicine, University of Minnesota, Saint Paul, MN 55108, USA
Am J Vet Res 71:940-5. 2010..To determine the relationship between serum cortisol concentration and pain severity as measured by force platform gait analysis in dogs with experimentally induced synovitis of the stifle joint...
Evaluation of analgesia resulting from extracorporeal shock wave therapy and radial pressure wave therapy in the limbs of horses and sheepScott R McClure
Department of Veterinary Clinical Sciences, College of Veterinary Medicine, Iowa State University, Ames, IA 50011, USA
Am J Vet Res 66:1702-8. 2005..CONCLUSIONS AND CLINICAL RELEVANCE: A small cutaneous analgesic effect may exist at the treatment site for approximately 3 days after ESWT or RPWT in horses...
Characterization of spatiotemporal gait characteristics in clinically normal dogs and dogs with spinal cord diseaseWanda J Gordon-Evans
Department of Veterinary Clinical Medicine, College of Veterinary Medicine, University of Illinois, Urbana, IL 61802, USA
Am J Vet Res 70:1444-9. 2009..CONCLUSIONS AND CLINICAL RELEVANCE-Use of spatiotemporal gait characteristics appears to have potential for use as an outcome measure for dogs with neurologic disease...
Effects of extracorporeal shock wave therapy on wounds of the distal portion of the limbs in horsesDean D Morgan
Department of Veterinary Clinical Sciences, College of Veterinary Medicine, Iowa State University, Ames, IA 50011, USA
J Am Vet Med Assoc 234:1154-61. 2009..To evaluate the effects of focused, extracorporeal shock wave therapy (ESWT) on the healing of wounds of the distal portion of the limbs in horses...
Identification of chromosomal regions associated with cranial cruciate ligament rupture in a population of NewfoundlandsVicki L Wilke
Department of Veterinary Clinical Sciences, College of Veterinary Medicine, Iowa State University, Ames, IA 50011, USA
Am J Vet Res 70:1013-7. 2009..To identify chromosomal regions associated with cranial cruciate ligament rupture (CCLR) in a population of Newfoundlands...
In vitro antibacterial properties of magnesium metal against Escherichia coli, Pseudomonas aeruginosa and Staphylococcus aureusDuane A Robinson
Veterinary Clinical Sciences Department, College of Veterinary Medicine, Iowa State University, Ames, IA 50011, USA
Acta Biomater 6:1869-77. 2010..The results demonstrate an antibacterial effect of Mg on three common aerobic bacterial organisms, the mechanism of which appears to be an alkaline pH...
Immunohistochemical evaluation of substance P and calcitonin gene-related peptide in skin and periosteum after extracorporeal shock wave therapy and radial pressure wave therapy in sheepJanan M Abed
Department of Veterinary Clinical Sciences, College of Veterinary Medicine, Iowa State University, Ames, IA 50011, USA
Am J Vet Res 68:323-8. 2007....
Susceptibility of Ochlerotatus trivittatus (Coq.), Aedes albopictus (Skuse), and Culex pipiens (L.) to West Nile virus infectionSonthaya Tiawsirisup
Department of Entomology, College of Agriculture, Iowa State University, Ames, Iowa 50014, USA
Vector Borne Zoonotic Dis 4:190-7. 2004..2 (3.4-4.6)) CID50s/mL, the predicted ID10+/-95% CI of Oc. trivittatus. Consequently this mosquito, which also feeds on humans and birds has the potential to serve as a bridge vector and as a maintenance vector among mammals...
Relationship between objective and subjective assessment of limb function in normal dogs with an experimentally induced lamenessAndrew S Waxman
College of Veterinary Medicine, Iowa State University, Ames, IA, USA
Vet Surg 37:241-6. 2008..To evaluate the relationship between previously used subjective and objective measures of limb function in normal dogs that had an induced lameness...
Evaluation of a ceftiofur-washed whole cell Streptococcus suis bacterin in pigsFrancisco J Pallares
Department of Veterinary Diagnostic and Production Animal Medicine, College of Veterinary Medicine, Iowa State University, Ames, Iowa 50011, USA
Can J Vet Res 68:236-40. 2004..suis bacterin with Montanide ISA 50 adjuvant significantly (P < 0.05) reduced bacteremia, meningitis, pneumonia, and mortality associated with S. suis challenge. Further work on this novel approach to bacterin production is warranted...
Distribution of vertical forces in the pads of Greyhounds and Labrador Retrievers during walkingM Faulkner Besancon
Department of Veterinary Clinical Sciences, College of Veterinary Medicine, Iowa State University, Ames, IA 50011, USA
Am J Vet Res 65:1497-501. 2004..However, loads were fairly evenly distributed, and DP-5 and the McP or MtP bear a substantial amount of load in both breeds...
Effect of surgical technique on limb function after surgery for rupture of the cranial cruciate ligament in dogsMichael G Conzemius
Orthopaedic Research Laboratory, Department of Veterinary Clinical Sciences, College of Veterinary Medicine, Iowa State University, Ames, IA 50010, USA
J Am Vet Med Assoc 226:232-6. 2005..Results of LSS and TPLO are similar and superior to ICS...
