F C Minion

Summary

Affiliation: Iowa State University
Country: USA

Publications

  1. pmc In vivo expression analysis of the P97 and P102 paralog families of Mycoplasma hyopneumoniae
    Cary Adams
    Department of Veterinary Microbiology and Preventive Medicine, Iowa State University, Ames, IA 50011, USA
    Infect Immun 73:7784-7. 2005
  2. pmc Enhanced murine antigen-specific gamma interferon and immunoglobulin G2a responses by using mycobacterial ESAT-6 sequences in DNA vaccines
    F Chris Minion
    Department of Veterinary Microbiology and Preventive Medicine, Iowa State University, Ames, IA 50011, USA
    Infect Immun 71:2239-43. 2003
  3. ncbi request reprint Molecular pathogenesis of mycoplasma animal respiratory pathogens
    F Chris Minion
    Dept Veterinary Microbiology and Preventive Medicine, Iowa State University, Ames, IA 50011, USA
    Front Biosci 7:d1410-22. 2002
  4. pmc R1 region of P97 mediates adherence of Mycoplasma hyopneumoniae to swine cilia
    F C Minion
    Department of Veterinary Microbiology and Preventive Medicine, Veterinary Medical Research Institute, Iowa State University, Ames, Iowa 50011, USA
    Infect Immun 68:3056-60. 2000
  5. pmc The genome sequence of Mycoplasma hyopneumoniae strain 232, the agent of swine mycoplasmosis
    F Chris Minion
    Department of Veterinary Microbiology and Preventive Medicine, Iowa State University, Ames, IA 50011, USA
    J Bacteriol 186:7123-33. 2004
  6. ncbi request reprint Molecular analysis of the P97 cilium adhesin operon of Mycoplasma hyopneumoniae
    T Hsu
    Department of Microbiology, Immunology and Preventive Medicine, Veterinary Medical Research Institute, Iowa State University, Ames, IA 50011, USA
    Gene 214:13-23. 1998
  7. ncbi request reprint Mycobacterial ESAT-6 protein enhances mouse IFN-gamma responses to Mycoplasma hyopneumoniae P71 protein
    Sreekumar A Menon
    Department of Veterinary Microbiology and Preventive Medicine, Veterinary Medical Research Institute, Iowa State University, Ames, IA 50011, USA
    J Interferon Cytokine Res 22:807-13. 2002
  8. pmc Immune responses to defined antigens of Mycobacterium bovis in cattle experimentally infected with Mycobacterium kansasii
    W R Waters
    United States Department of Agriculture, Agricultural Research Service, National Animal Disease Center, P O Box 70, Ames, IA 50010 0070, USA
    Clin Vaccine Immunol 13:611-9. 2006
  9. pmc Cloning and functional analysis of the P97 swine cilium adhesin gene of Mycoplasma hyopneumoniae
    T Hsu
    Department of Microbiology, Immunology, and Preventive Medicine, Veterinary Medical Research Institute, Iowa State University, Ames 50011, USA
    J Bacteriol 179:1317-23. 1997
  10. pmc Physical map of the genome of Acholeplasma oculi ISM1499 and construction of a Tn4001 derivative for macrorestriction chromosomal mapping
    E Tigges
    Veterinary Medical Research Institute, Iowa State University, Ames 50011
    J Bacteriol 176:1180-3. 1994

Collaborators

Detail Information

Publications36

  1. pmc In vivo expression analysis of the P97 and P102 paralog families of Mycoplasma hyopneumoniae
    Cary Adams
    Department of Veterinary Microbiology and Preventive Medicine, Iowa State University, Ames, IA 50011, USA
    Infect Immun 73:7784-7. 2005
    ..We tested whether these genes were expressed during infection. P102 is associated with the mycoplasma and with swine cilia. Further, most of the paralogs were transcribed in vivo in two gene transcriptional units...
  2. pmc Enhanced murine antigen-specific gamma interferon and immunoglobulin G2a responses by using mycobacterial ESAT-6 sequences in DNA vaccines
    F Chris Minion
    Department of Veterinary Microbiology and Preventive Medicine, Iowa State University, Ames, IA 50011, USA
    Infect Immun 71:2239-43. 2003
    ..In conclusion, ESAT-6 was shown to enhance antigen-specific type 1 immune responses in BALB/c mice when used in DNA vaccines...
  3. ncbi request reprint Molecular pathogenesis of mycoplasma animal respiratory pathogens
    F Chris Minion
    Dept Veterinary Microbiology and Preventive Medicine, Iowa State University, Ames, IA 50011, USA
    Front Biosci 7:d1410-22. 2002
    ..These advances give insight to an extraordinary group of organisms that interact with their hosts in unique and intriguing ways...
  4. pmc R1 region of P97 mediates adherence of Mycoplasma hyopneumoniae to swine cilia
    F C Minion
    Department of Veterinary Microbiology and Preventive Medicine, Veterinary Medical Research Institute, Iowa State University, Ames, Iowa 50011, USA
    Infect Immun 68:3056-60. 2000
    ..These results could lead to more effective therapeutic measures against this important swine pathogen...
  5. pmc The genome sequence of Mycoplasma hyopneumoniae strain 232, the agent of swine mycoplasmosis
    F Chris Minion
    Department of Veterinary Microbiology and Preventive Medicine, Iowa State University, Ames, IA 50011, USA
    J Bacteriol 186:7123-33. 2004
    ..hyopneumoniae contains few genes with tandem repeat sequences that could be involved in phase switching or antigenic variation. Thus, it is not clear how M. hyopneumoniae evades the immune response and establishes a chronic infection...
  6. ncbi request reprint Molecular analysis of the P97 cilium adhesin operon of Mycoplasma hyopneumoniae
    T Hsu
    Department of Microbiology, Immunology and Preventive Medicine, Veterinary Medical Research Institute, Iowa State University, Ames, IA 50011, USA
    Gene 214:13-23. 1998
    ..The function of P102 is also not known, but the translated sequence shows a prominent transmembrane domain, suggesting that it may be a surface protein...
  7. ncbi request reprint Mycobacterial ESAT-6 protein enhances mouse IFN-gamma responses to Mycoplasma hyopneumoniae P71 protein
    Sreekumar A Menon
    Department of Veterinary Microbiology and Preventive Medicine, Veterinary Medical Research Institute, Iowa State University, Ames, IA 50011, USA
    J Interferon Cytokine Res 22:807-13. 2002
    ..05) IgG2a antibody levels in comparison to immunizing with P71 alone. These results demonstrate that ESAT-6 can modify the profile of an immunologic response to an accompanying immunogen...
  8. pmc Immune responses to defined antigens of Mycobacterium bovis in cattle experimentally infected with Mycobacterium kansasii
    W R Waters
    United States Department of Agriculture, Agricultural Research Service, National Animal Disease Center, P O Box 70, Ames, IA 50010 0070, USA
    Clin Vaccine Immunol 13:611-9. 2006
    ..bovis infection. These findings indicate that M. kansasii infection of calves elicits specific responses that may confound the interpretation of bovine tuberculosis tests...
  9. pmc Cloning and functional analysis of the P97 swine cilium adhesin gene of Mycoplasma hyopneumoniae
    T Hsu
    Department of Microbiology, Immunology, and Preventive Medicine, Veterinary Medical Research Institute, Iowa State University, Ames 50011, USA
    J Bacteriol 179:1317-23. 1997
    ..hyopneumoniae bound specifically to swine cilia, and the binding was inhibited by heparin and fucoidan, thus supporting the hypothesis that P97 was actively involved in binding to swine cilia in vivo...
  10. pmc Physical map of the genome of Acholeplasma oculi ISM1499 and construction of a Tn4001 derivative for macrorestriction chromosomal mapping
    E Tigges
    Veterinary Medical Research Institute, Iowa State University, Ames 50011
    J Bacteriol 176:1180-3. 1994
    ..The total size of the A. oculi ISM1499 genome was estimated to be 1,633 kb. The restriction enzyme sites for ApaI, BssHII, EagI, and SmaI were positioned on the map along with several transposon insertion sites...
  11. ncbi request reprint Use of a Mycoplasma hyopneumoniae nested polymerase chain reaction test to determine the optimal sampling sites in swine
    Kathy T Kurth
    Department of Veterinary Microbiology and Preventive Medicine, Veterinary Medical Research Institute, Iowa State University, Ames 50011, USA
    J Vet Diagn Invest 14:463-9. 2002
    ..In conclusion, the nested PCR developed for this study was found to be a highly sensitive and specific diagnostic tool for M. hyopneumoniae, but the enhanced sensitivity may be unnecessary if the proper sites are sampled...
  12. pmc Transcriptome changes in Mycoplasma hyopneumoniae during infection
    Melissa L Madsen
    Department of Veterinary Microbiology and Preventive Medicine, Iowa State University, Ames, IA 50011, USA
    Infect Immun 76:658-63. 2008
    ..003), adenylate kinase (adk [mhp208]) (P = 0.001), prolyl aminoacyl tRNA synthetase (proS [mhp397]) (P = 0.009), and cysteinyl-tRNA synthetase (cysS [mhp661]) (P < 0.001) were down-regulated in vivo...
  13. pmc Real-time PCR assays to address genetic diversity among strains of Mycoplasma hyopneumoniae
    Erin L Strait
    Department of Veterinary Microbiology and Preventive Medicine, Iowa State University, Ames, IA 50011, USA
    J Clin Microbiol 46:2491-8. 2008
    ..hyopneumoniae. To increase the efficiency of PCR testing, two new real-time PCR assays that are specific and capable of detecting all of the M. hyopneumoniae isolates used in this study were developed...
  14. ncbi request reprint Phylogenetic analysis of mycoplasma strain ISM1499 and its assignment to the Acholeplasma oculi strain cluster
    S Artiushin
    Veterinary Medical Research Institute, Iowa State University, Ames 50011
    Int J Syst Bacteriol 45:104-9. 1995
    ..oculi 19L and ISM1499 and in the 16S ribosomal DNA sequences of A. laidlawii PG8 and JA1 may indicate that unusual dissimilarities occur in the 16S ribosomal DNA sequences of members of the genus Acholeplasma...
  15. ncbi request reprint Global transcriptional analysis of Mycoplasma hyopneumoniae following exposure to hydrogen peroxide
    Erin R Schafer
    Department of Veterinary Microbiology and Preventive Medicine, Iowa State University, Ames, IA 50011, USA
    Microbiology 153:3785-90. 2007
    ..This study has also revealed significantly differentially expressed genes common to other environmental stress responses, indicating that further investigation of universal stress response genes of M. hyopneumoniae is merited...
  16. doi request reprint Global transcriptional analysis of Mycoplasma hyopneumoniae following exposure to norepinephrine
    Michael J Oneal
    Department of Veterinary Microbiology and Preventive Medicine, Iowa State University, Ames, IA 50011, USA
    Microbiology 154:2581-8. 2008
    ..Approximately 51 % of the genes were hypothetical with no known function. Thus, in response to norepinephrine, M. hyopneumoniae appears to upregulate protein expression while downregulating general metabolism...
  17. ncbi request reprint Cloning and analysis of the gene for a major surface antigen of Mycoplasma gallisepticum
    Denise L Spencer
    Veterinary Medical Research Institute, Iowa State University, Ames, IA 50011, USA
    Avian Dis 46:816-25. 2002
    ..Recombinant P75 is not recognized in immunoblots by convalescent sera produced in chickens infected with Mycoplasma synoviae, Mycoplasma gallinarum, and Mycoplasma gallinaceum or in turkeys infected with Mycoplasma meleagridis...
  18. pmc Diagnostic implications of antigen-induced gamma interferon production by blood leukocytes from Mycobacterium bovis-infected reindeer (Rangifer tarandus)
    W R Waters
    National Animal Disease Center, 2300 Dayton Ave, P O Box 70, Ames, IA 50010, USA
    Clin Vaccine Immunol 13:37-44. 2006
    ..Together, these findings indicate that IFN-gamma-based tests may prove useful for TB surveillance of reindeer...
  19. doi request reprint Detection and quantification of intergenic transcription in Mycoplasma hyopneumoniae
    Stuart W Gardner
    Department of Veterinary Microbiology and Preventive Medicine, Interdepartmental Microbiology Program, Iowa State University, Ames, IA 50011, USA
    Microbiology 156:2305-15. 2010
    ..Rather, transcription continues past the end of the ORF, with RNA polymerase gradually releasing the template. Transcription can also be initiated within IG regions in the absence of accepted promoter-like sequences...
  20. ncbi request reprint Construction of mini-Tn4001tet and its use in Mycoplasma gallisepticum
    Ina Pour-El
    Veterinary Medical Research Institute, Ames, Iowa 50011, USA
    Plasmid 47:129-37. 2002
    ..Insertions of mini-Tn4001tet were random and only single insertions were observed. Several unique restriction sites between the inverted repeat sequences provide for further development of mini-Tn4001...
  21. pmc Array-based genomic comparative hybridization analysis of field strains of Mycoplasma hyopneumoniae
    Melissa L Madsen
    Department of Veterinary Microbiology and Preventive Medicine, Iowa State University, Ames, IA 50011, USA
    J Bacteriol 189:7977-82. 2007
    ..A permutation test identified a location in the M. hyopneumoniae genome where there is spatial clustering of variability between the field strains and strain 232...
  22. pmc Mycoplasma hyopneumoniae increases intracellular calcium release in porcine ciliated tracheal cells
    Seung Chun Park
    Department of Biomedical Sciences, Iowa State University, Ames, Iowa 50011, USA
    Infect Immun 70:2502-6. 2002
    ..Thus, an increase in Ca2+ may serve as a signal for the pathogenesis of M. hyopneumoniae...
  23. doi request reprint Transcriptome analysis of organisms with food safety relevance
    Supraja Puttamreddy
    Department of Veterinary Microbiology and Preventive Medicine, Iowa State University, Ames, Iowa 50011, USA
    Foodborne Pathog Dis 5:517-29. 2008
    ..This review should not be considered as a comprehensive review, and where appropriate, species-specific reviews are cited that are more complete...
  24. pmc Transcriptional profiling of Mycoplasma hyopneumoniae during heat shock using microarrays
    Melissa L Madsen
    Department of Veterinary Microbiology and Preventive Medicine, Iowa State University, Ames, IA 50011, USA
    Infect Immun 74:160-6. 2006
    ..5-fold or greater. Many of the heat shock proteins previously characterized in other bacteria were identified as significant in this study as well. A proportion of the identified genes (54 of 91) currently have no assigned function...
  25. ncbi request reprint Antigen-specific proliferation and activation of peripheral blood mononuclear cells from Mycobacterium bovis-infected reindeer
    W Ray Waters
    National Animal Disease Center, Agricultural Research Service, United States Department of Agriculture, P O Box 70, Ames, IA 50010, USA
    Vet Immunol Immunopathol 111:263-77. 2006
    ..Present in vitro findings, therefore, may be predictive of host responses by reindeer that limit progression to disseminated disease...
  26. ncbi request reprint Transcriptional profiling of Mycoplasma hyopneumoniae during iron depletion using microarrays
    Melissa L Madsen
    Department of Veterinary Microbiology and Preventive Medicine, Iowa State University, Ames, IA, USA
    Microbiology 152:937-44. 2006
    ..Ten of the 27 identified genes had no assigned function. These studies indicate that M. hyopneumoniae can respond to changes in environmental conditions, but the mechanism employed remains unknown...
  27. pmc Genome-wide transposon mutagenesis reveals a role for pO157 genes in biofilm development in Escherichia coli O157:H7 EDL933
    Supraja Puttamreddy
    Department of Veterinary Microbiology and Preventive Medicine, Iowa State University, Ames, IA 50011, USA
    Infect Immun 78:2377-84. 2010
    ..In addition, EhxD and EspP were also important for adherence to T84 intestinal epithelial cells, suggesting a role for these genes in tissue interactions in vivo...
  28. ncbi request reprint The pyruvate dehydrogenase complex of Mycoplasma hyopneumoniae contains a novel lipoyl domain arrangement
    Jake N Matic
    Microbiology and Immunology Section, Elizabeth Macarthur Agricultural Institute, Private Mail Bag 8, Camden, NSW, Australia
    Gene 319:99-106. 2003
    ..However, like other bacterial species, pdhC gene sequences from Mycoplasma capricolum, Mycoplasma genitalium and Mycoplasma pneumoniae contain a putative lipoyl domain...
  29. ncbi request reprint An ESAT-6:CFP10 DNA vaccine administered in conjunction with Mycobacterium bovis BCG confers protection to cattle challenged with virulent M. bovis
    Alexander C Maue
    Department of Molecular Microbiology and Immunology, University of Missouri, Columbia, MO 65211, USA
    Vaccine 25:4735-46. 2007
    ..These data suggest that a combined vaccine regimen of M. bovis BCG and a candidate ESAT-6:CFP10 DNA vaccine may offer greater protection against tuberculosis in cattle than vaccination with BCG alone...
  30. pmc Proteolytic processing of the Mycoplasma hyopneumoniae cilium adhesin
    Steven P Djordjevic
    New South Wales Agriculture, Elizabeth Macarthur Agricultural Institute, Camden, New South Wales 2570, Australian
    Infect Immun 72:2791-802. 2004
    ..The ability of M. hyopneumoniae to selectively cleave its secreted proteins provides this pathogen with a remarkable capacity to alter its surface architecture...
  31. ncbi request reprint P159 is a proteolytically processed, surface adhesin of Mycoplasma hyopneumoniae: defined domains of P159 bind heparin and promote adherence to eukaryote cells
    Tracey A Burnett
    NSW Department of Primary Industries, Elizabeth Macarthur Agricultural Institute, Camden, NSW 2570, Australia
    Mol Microbiol 60:669-86. 2006
    ..These findings indicate that P159 is a post-translationally cleaved, glycosaminoglycan-binding adhesin of M. hyopneumoniae...
  32. ncbi request reprint CD80 and CD86, but not CD154, augment DNA vaccine-induced protection in experimental bovine tuberculosis
    Alexander C Maue
    Department of Molecular Microbiology and Immunology, University of Missouri, Columbia, MO 65211, USA
    Vaccine 23:769-79. 2004
    ....
  33. pmc Analysis of immune responses directed toward a recombinant early secretory antigenic target six-kilodalton protein-culture filtrate protein 10 fusion protein in Mycobacterium bovis-infected cattle
    Alexander C Maue
    Department of Molecular Microbiology and Immunology, University of Missouri, Columbia, 65211, USA
    Infect Immun 73:6659-67. 2005
    ..Collectively, data indicate that recall immune responses directed toward the rESAT-6-CFP10 fusion protein or purified protein derivative are comparable and that recall to mycobacterial antigens correlates with a CD45RO(+) phenotype...
  34. doi request reprint Mycoplasmas regulate the expression of heat-shock protein genes through CIRCE-HrcA interactions
    Li Jen Chang
    Department of Life Science, Institute of Biotechnology, National Dong Hwa University, 1 University Street, Hualien, Taiwan 974, ROC
    Biochem Biophys Res Commun 367:213-8. 2008
    ..It is conceivable that mycoplasmas may have evolved a single HrcA repressor-based mechanism which might be the most simple and economical way of controlling HSP gene expression...
  35. pmc Two domains within the Mycoplasma hyopneumoniae cilium adhesin bind heparin
    Cheryl Jenkins
    Microbiology and Immunology, Elizabeth Macarthur Agricultural Institute, PMB 8, Camden, New South Wales 2570, Australia
    Infect Immun 74:481-7. 2006
    ..hyopneumoniae to host respiratory surfaces and therefore has important implications with respect to the pathogenesis of this organism...
  36. ncbi request reprint Characterization of In Vivo acquired resistance of Mycoplasma hyopneumoniae to macrolides and lincosamides
    Tim Stakenborg
    Veterinary and Agrochemical Research Centre, Brussels, Belgium
    Microb Drug Resist 11:290-4. 2005
    ..The present study showed that 23S rRNA mutations resulting in resistance to macrolides and lincosamides as described in other Mycoplasma spp. also occur under field conditions in M. hyopneumoniae...