Albert Jergens

Summary

Affiliation: Iowa State University
Country: USA

Publications

  1. ncbi request reprint Interobserver variation among histopathologic evaluations of intestinal tissues from dogs and cats
    Michael D Willard
    Department of Small Animal Medicine and Surgery, College of Veterinary Medicine, Texas AM University, College Station 77843 44744, USA
    J Am Vet Med Assoc 220:1177-82. 2002
  2. doi request reprint Bcl-2/Caspase 3 mucosal imbalance favors T cell resistance to apoptosis in dogs with inflammatory bowel disease
    A Jergens
    Department of Veterinary Clinical Sciences, Iowa State University, Ames, IA 50010, USA Electronic address
    Vet Immunol Immunopathol 158:167-74. 2014
  3. doi request reprint Feline idiopathic inflammatory bowel disease: what we know and what remains to be unraveled
    Albert E Jergens
    Department of Veterinary Clinical Sciences, College of Veterinary Medicine, Iowa State University, Ames, IA 50011, USA
    J Feline Med Surg 14:445-58. 2012
  4. ncbi request reprint Inflammatory bowel disease in veterinary medicine
    Albert E Jergens
    Department of Veterinary Clinical Sciences, Iowa State University, Ames, Iowa 50010, USA
    Front Biosci (Elite Ed) 4:1404-19. 2012
  5. doi request reprint A clinical index for disease activity in cats with chronic enteropathy
    A E Jergens
    Department of Veterinary Clinical Sciences, College of Veterinary Medicine, Iowa State University, Ames, IA, USA
    J Vet Intern Med 24:1027-33. 2010
  6. doi request reprint Comparison of oral prednisone and prednisone combined with metronidazole for induction therapy of canine inflammatory bowel disease: a randomized-controlled trial
    A E Jergens
    Department of Veterinary Clinical Sciences, College of Veterinary Medicine, Iowa State University, Ames, IA 50010, USA
    J Vet Intern Med 24:269-77. 2010
  7. pmc Intestinal cytokine mRNA expression in canine inflammatory bowel disease: a meta-analysis with critical appraisal
    Albert E Jergens
    Department of Veterinary Clinical Sciences, Iowa State University, Ames, Iowa, USA
    Comp Med 59:153-62. 2009
  8. doi request reprint Fluorescence in situ hybridization confirms clearance of visible Helicobacter spp. associated with gastritis in dogs and cats
    A E Jergens
    Department of Veterinary Clinical Sciences, College of Veterinary Medicine, Iowa State University, Ames, IA, USA
    J Vet Intern Med 23:16-23. 2009
  9. ncbi request reprint Percutaneous endoscopic gastrojejunostomy tube placement in healthy dogs and cats
    Albert E Jergens
    Department of Veterinary Clinical Sciences, College of Veterinary Medicine, Iowa State University, Ames 50010, USA
    J Vet Intern Med 21:18-24. 2007
  10. pmc Helicobacter bilis triggers persistent immune reactivity to antigens derived from the commensal bacteria in gnotobiotic C3H/HeN mice
    Albert E Jergens
    Department of Veterinary Clinical Sciences, College of Veterinary Medicine, Iowa State University, Ames, IA 50011, USA
    Gut 56:934-40. 2007

Research Grants

Detail Information

Publications18

  1. ncbi request reprint Interobserver variation among histopathologic evaluations of intestinal tissues from dogs and cats
    Michael D Willard
    Department of Small Animal Medicine and Surgery, College of Veterinary Medicine, Texas AM University, College Station 77843 44744, USA
    J Am Vet Med Assoc 220:1177-82. 2002
    ....
  2. doi request reprint Bcl-2/Caspase 3 mucosal imbalance favors T cell resistance to apoptosis in dogs with inflammatory bowel disease
    A Jergens
    Department of Veterinary Clinical Sciences, Iowa State University, Ames, IA 50010, USA Electronic address
    Vet Immunol Immunopathol 158:167-74. 2014
    ..Mucosal imbalance of Bcl-2/caspase 3 expression favors T cell resistance to apoptosis which may contribute to T cell accumulation and chronic intestinal inflammation, similar to human IBD. ..
  3. doi request reprint Feline idiopathic inflammatory bowel disease: what we know and what remains to be unraveled
    Albert E Jergens
    Department of Veterinary Clinical Sciences, College of Veterinary Medicine, Iowa State University, Ames, IA 50011, USA
    J Feline Med Surg 14:445-58. 2012
    ..Affected cats may also have concurrent inflammation in other organs, such as the pancreas and liver, which may impact clinical disease severity...
  4. ncbi request reprint Inflammatory bowel disease in veterinary medicine
    Albert E Jergens
    Department of Veterinary Clinical Sciences, Iowa State University, Ames, Iowa 50010, USA
    Front Biosci (Elite Ed) 4:1404-19. 2012
    ..We also offer scientific comparison between human and canine IBD...
  5. doi request reprint A clinical index for disease activity in cats with chronic enteropathy
    A E Jergens
    Department of Veterinary Clinical Sciences, College of Veterinary Medicine, Iowa State University, Ames, IA, USA
    J Vet Intern Med 24:1027-33. 2010
    ..There is a need for a clinically useful, quantitative index for measurement of disease activity in cats with chronic enteropathy (CE)...
  6. doi request reprint Comparison of oral prednisone and prednisone combined with metronidazole for induction therapy of canine inflammatory bowel disease: a randomized-controlled trial
    A E Jergens
    Department of Veterinary Clinical Sciences, College of Veterinary Medicine, Iowa State University, Ames, IA 50010, USA
    J Vet Intern Med 24:269-77. 2010
    ..Although prednisone and metronidazole are commonly used to treat canine inflammatory bowel disease (IBD), no randomized-controlled trials have been performed...
  7. pmc Intestinal cytokine mRNA expression in canine inflammatory bowel disease: a meta-analysis with critical appraisal
    Albert E Jergens
    Department of Veterinary Clinical Sciences, Iowa State University, Ames, Iowa, USA
    Comp Med 59:153-62. 2009
    ..Heterogeneity of results among these studies might be explained by numerous factors including the method of mRNA quantification, stage of disease, and demographic differences in study populations...
  8. doi request reprint Fluorescence in situ hybridization confirms clearance of visible Helicobacter spp. associated with gastritis in dogs and cats
    A E Jergens
    Department of Veterinary Clinical Sciences, College of Veterinary Medicine, Iowa State University, Ames, IA, USA
    J Vet Intern Med 23:16-23. 2009
    ..in the pathogenesis of canine and feline gastritis are inconclusive. Furthermore, data evaluating the effectiveness of medical therapy for eradication of Helicobacter infection are limited...
  9. ncbi request reprint Percutaneous endoscopic gastrojejunostomy tube placement in healthy dogs and cats
    Albert E Jergens
    Department of Veterinary Clinical Sciences, College of Veterinary Medicine, Iowa State University, Ames 50010, USA
    J Vet Intern Med 21:18-24. 2007
    ..A thorough description of the percutaneous endoscopic gastrojejunostomy (PEG-J) technique and practical guidelines for its use in small animals have not been reported...
  10. pmc Helicobacter bilis triggers persistent immune reactivity to antigens derived from the commensal bacteria in gnotobiotic C3H/HeN mice
    Albert E Jergens
    Department of Veterinary Clinical Sciences, College of Veterinary Medicine, Iowa State University, Ames, IA 50011, USA
    Gut 56:934-40. 2007
    ..However, consensus regarding the role of Helicobacter as a model organism to study microbial-induced IBD is confounded by the presence of a complex colonic microbiota...
  11. ncbi request reprint Induction of differential immune reactivity to members of the flora of gnotobiotic mice following colonization with Helicobacter bilis or Brachyspira hyodysenteriae
    Albert E Jergens
    Department of Veterinary Microbiology and Preventive Medicine, College of Veterinary Medicine, Iowa State University, Ames, IA 50011, USA
    Microbes Infect 8:1602-10. 2006
    ..These results indicate that microbial perturbation may induce differential immune responses to nonpathogenic resident bacteria that can lead to intestinal inflammation...
  12. ncbi request reprint A scoring index for disease activity in canine inflammatory bowel disease
    Albert E Jergens
    Department of Veterinary Clinical Sciences, College of Veterinary Medicine, Iowa State University, Ames, IA 50011, USA
    J Vet Intern Med 17:291-7. 2003
    ..We conclude that the CIBDAI is a reliable measure of inflammatory activity in canine IBD and that CRP is suitable for laboratory evaluation of the effect of therapy in these patients...
  13. doi request reprint Prophylactic treatment with Hypoxis hemerocallidea corm (African potato) methanolic extract ameliorates Brachyspira hyodysenteriae-induced murine typhlocolitis
    Zhiping Liu
    Department of Veterinary Microbiology and Preventive Medicine, College of Veterinary Medicine, Iowa State University, Ames, IA 50010 3020, USA
    Exp Biol Med (Maywood) 235:222-30. 2010
    ..hyodysenteriae-induced typhlocolitis, suggesting H. hemerocallidea corm methanolic extract may have potential for ameliorating enteropathies that are mediated by overactive host inflammatory processes...
  14. ncbi request reprint Clinical assessment of disease activity for canine inflammatory bowel disease
    Albert E Jergens
    Department of Veterinary Clinical Sciences, College of Veterinary Medicine, Iowa State University, Ames, Iowa 50011, USA
    J Am Anim Hosp Assoc 40:437-45. 2004
    ..The clinical application of a simple scoring index (e.g., canine IBD activity index [CIBDAI]) for measurement of canine IBD activity is also reviewed...
  15. doi request reprint Mucosal gene expression profiles following the colonization of immunocompetent defined-flora C3H mice with Helicobacter bilis: a prelude to typhlocolitis
    Zhiping Liu
    Department of Veterinary Microbiology and Preventive Medicine, Iowa State University, Ames, IA, USA
    Microbes Infect 11:374-83. 2009
    ..This study provides preliminary evidence as to the types of factors or changes in the intestinal mucosa that potentially predispose the host to the development of typhlocolitis...
  16. pmc Influenza A pandemic (H1N1) 2009 virus infection in domestic cat
    Brett A Sponseller
    College of Veterinary Medicine, Iowa State University, Ames, Iowa 50011 1248, USA
    Emerg Infect Dis 16:534-7. 2010
    ..In 2009, pandemic (H1N1) 2009 infection in a domestic cat from Iowa was diagnosed by a novel PCR assay that distinguishes between Eurasian and North American pandemic (H1N1) 2009 virus matrix genes. Human-to-cat transmission is presumed...
  17. ncbi request reprint [The role of antibiotics in lesions of the digestive tract in dogs and cats]
    Albert E Jergens
    Tijdschr Diergeneeskd 127:262-4. 2002
  18. ncbi request reprint [Inflammatory bowel disease (IBD): development in the area of diagnosis and treatment]
    Albert E Jergens
    Tijdschr Diergeneeskd 127:300-1. 2002

Research Grants4

  1. Enteric flora modulates the development of colitis
    Albert Jergens; Fiscal Year: 2007
    ..g., graduate students and postdoctoral fellow). There are ample opportunities to attend seminars, journal clubs and work-in-progress research meetings during which the applicant can become engaged in scientific discussions. ..