Research Topics
Species | Suzanne HendrichSummaryAffiliation: Iowa State University Country: USA Publications
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Publications
Glycemic index, insulinemic index, and satiety index of kefirKai Ling Kong
Food Science and Human Nutrition, Iowa State University, Ames, IA 50011, USA
J Am Coll Nutr 31:280-7. 2012..To determine glycemic, insulinemic, and satiety indices of 3 types of kefir...
Bioavailability of isoflavonesSuzanne Hendrich
Food Science and Human Nutrition, Iowa State University, 2312 Food Science Building, Ames, IA 50011, USA
J Chromatogr B Analyt Technol Biomed Life Sci 777:203-10. 2002....
Artichoke extract lowered plasma cholesterol and increased fecal bile acids in Golden Syrian hamstersZhiyi Qiang
Department of Food Science and Human Nutrition, Iowa State University, Ames, IA, USA
Phytother Res 26:1048-52. 2012..4% and 25% in ALE fed females compared with controls. The ALE lowered hamster plasma cholesterol levels by a mechanism involving the greater excretion of fecal bile acids and neutral sterols after feeding for 42 days...
Isoflavone glycitein diminished plasma cholesterol in female golden Syrian hamstersSun Ok Lee
Food Science and Human Nutrition, Iowa State University, Ames 50011, USA
J Agric Food Chem 55:11063-7. 2007..These data suggest that glycitein's greater cholesterol-lowering effect was due to its greater bioavailability, as reflected in its urinary recovery compared with that of the other isoflavones...
High urinary isoflavone excretion phenotype decreases plasma cholesterol in golden Syrian hamsters fed soy proteinZhong Ye
Food Science and Human Nutrition, Iowa State University, Ames, IA 50011-1123, USA
J Nutr 136:2773-8. 2006..Isoflavone absorbability, probably due to gut microbial ecology, is an important controllable variable in studies of effects of soy protein on blood lipids...
Metabolism of glycitein (7,4'-dihydroxy-6-methoxy-isoflavone) by human gut microfloraAndrean L Simons
Department of Food Science and Human Nutrition, 2312 Food Sciences Building, Iowa State University, Ames, IA 50011, USA
J Agric Food Chem 53:8519-25. 2005..These results show that glycitein is metabolized by human gut microorganisms and may follow metabolic pathways similar to other soy isoflavones...
Permeability of rosmarinic acid in Prunella vulgaris and ursolic acid in Salvia officinalis extracts across Caco-2 cell monolayersZhiyi Qiang
Department of Food Science and Human Nutrition, Iowa State University, Ames, IA, USA
J Ethnopharmacol 137:1107-12. 2011....
Fumonisin B-glucose reaction products are less toxic when fed to swineGuillermo Fernández-Surumay
Interdepartmental Toxicology Program, Iowa State University, Ames, Iowa 50011, USA
J Agric Food Chem 53:4264-71. 2005..Tissues of controls were free of lesions. Results suggest that dietary FB-G products are less toxic to swine and may provide an detoxification approach in instances of widespread FB grain contamination (p < 0.05)...
The apparent absorptions of isoflavone glucosides and aglucons are similar in women and are increased by rapid gut transit time and low fecal isoflavone degradationYan Zheng
Food Science and Human Nutrition, Iowa State University, Ames, IA 50011, USA
J Nutr 134:2534-9. 2004..8 +/- 0.3 vs. 0.5 +/- 0.3%, P < 0.05). Urinary excretions of aglucons and glucosides did not differ. The study confirmed that rapid GTT and low fecal isoflavone degradation rate increased the apparent absorption of isoflavones...
Soyasaponins lowered plasma cholesterol and increased fecal bile acids in female golden Syrian hamstersSun-Ok Lee
Food Science and Human Nutrition, 124 MacKay Hall, Iowa State University, Ames, IA 50011, USA
Exp Biol Med (Maywood) 230:472-8. 2005....
Lesser in vitro anaerobic cecal isoflavone disappearance was associated with greater apparent absorption of daidzein and genistein in Golden Syrian hamstersMathieu Renouf
Food Science and Human Nutrition, Iowa State University, 220 MacKay, Ames, IA 50011, USA
Food Funct 2:273-8. 2011..The sex difference in isoflavone excretion in hamsters and the instability in glycitein excretion across studies coupled with the paucity of human data on this isoflavone deserve further investigation...
Greater apparent absorption of flavonoids is associated with lesser human fecal flavonoid disappearance ratesAndrean L Simons
Department of Food Science and Human Nutrition, Iowa State University, Ames, Iowa 50011, USA
J Agric Food Chem 58:141-7. 2010..2+/-4.6%), hesperetin (7.3+/-3.2%), and quercetin (5.6+/-3.7%) compared with daidzein (43.4+/-15.5%, p=0.02). These data affirmed the hypothesis that the 5,7,4'-OH of flavonoids limited apparent absorption of these compounds in humans...
Bacteroides uniformis is a putative bacterial species associated with the degradation of the isoflavone genistein in human fecesMathieu Renouf
Food Science and Human Nutrition, Iowa State University, Ames, IA 50011, USA
J Nutr 141:1120-6. 2011..These fecal microbes are candidate biomarkers for interindividual variation in isoflavone uptake and efficacy...
Efficacy of a mycotoxin binder against dietary fumonisin, deoxynivalenol, and zearalenone in ratsZhiyi Qiang
Department of Food Science and Human Nutrition, Iowa State University, Ames, IA 50011, USA
J Agric Food Chem 59:7527-33. 2011..Grainsure E prevented some effects of fumonisin B1 and deoxynivalenol in rats...
Soyasaponin I and sapongenol B have limited absorption by Caco-2 intestinal cells and limited bioavailability in womenJiang Hu
Department of Food Science and Human Nutrition, Iowa State University, Ames, IA 50011, USA
J Nutr 134:1867-73. 2004..Therefore, ingested soyasaponins have low absorbability in human intestinal cells and seem to be metabolized to soyasapogenol B by human intestinal microorganisms in vivo and excreted in the feces...
Deoxynivalenol suppresses circulating and splenic leukocyte subpopulations in BALB/c mice: dose response, time course and sex differencesXianai Wu
Department of Food Science and Human Nutrition, Iowa State University, Ames, 50011, USA
Food Addit Contam Part A Chem Anal Control Expo Risk Assess 26:1070-80. 2009..This suggests that female sex hormones potentiate one potential marker of DON immunotoxicity in BALB/c mice...
Human fecal metabolism of soyasaponin IJiang Hu
Department of Food Science and Human Nutrition, and College of Veterinary Medicine, Iowa State University, 2312 Food Science Building, Ames, Iowa 50011, USA
J Agric Food Chem 52:2689-96. 2004..These results indicate that dietary soyasaponins can be metabolized by human gut microorganisms. The sugar moieties of soyasaponins seem to be hydrolyzed sequentially to yield smaller and more hydrophobic metabolites...
Soy protein with or without isoflavones, soy germ and soy germ extract, and daidzein lessen plasma cholesterol levels in golden Syrian hamstersTongtong Song
Food Science and Human Nutrition, Iowa State University, Ames, Iowa 50011, USA
Exp Biol Med (Maywood) 228:1063-8. 2003....
Synthesis and characterization of deoxynivalenol glucuronide: its comparative immunotoxicity with deoxynivalenolXianai Wu
Department of Food Science and Human Nutrition, Iowa State University, 224D Mackay Hall, Ames, IA 50011, USA
Food Chem Toxicol 45:1846-55. 2007..DONGLU did not influence DON toxicity at 0.5 microM, 1.3 microM and 8.4 microM concentration combinations of each compound. These data verified that DONGLU is a detoxification product of DON...
Increased CYP4B1 mRNA is associated with the inhibition of dextran sulfate sodium-induced colitis by caffeic acid in miceZhong Ye
The Iowa State University, Department of Food Science and Human Nutrition, 224D MacKay, Ames, IA 50011, USA
Exp Biol Med (Maywood) 234:605-16. 2009..The inhibition of DSS-induced colitic pathology by caffeic acid was mediated by mechanisms in addition to anti-inflammatory effects that deserve further study...
Human gut microbial degradation of flavonoids: structure-function relationshipsAndrean L Simons
Department of Food Science and Human Nutrition, Iowa State University, 2312 Food Sciences Building, Ames, Iowa 50011, USA
J Agric Food Chem 53:4258-63. 2005..Extensive degradation of flavonoids by gut microflora may result in lower overall bioavailability than those flavonoids that are slowly degraded because rapidly degrading flavonoids are less likely to be absorbed intact...
Inhibition of azoxymethane-induced preneoplastic lesions in the rat colon by a cooked stearic acid complexed high-amylose cornstarchYinsheng Zhao
Department of Food Science and Human Nutrition, 220 MacKay Hall, Iowa State University, Ames, Iowa 50011 1123, United States
J Agric Food Chem 59:9700-8. 2011..This study revealed the effectiveness of a novel resistant starch in inhibiting colonic preneoplastic lesions and the importance of high-moisture cooking on the suppression of colon carcinogenesis by this resistant starch...
Glucose reaction with fumonisin B1 partially reduces its toxicity in swineGuillermo Fernández-Surumay
Interdepartmental Toxicology Program, Department of Veterinary Diagnostic and Production Animal Medicine, Iowa State University, Ames, IA 50011, USA
J Agric Food Chem 52:7732-9. 2004..The levels of sphinganine and sphinganine/sphingosine ratios in serum and liver as well as pathologic findings provided definitive evidence of protection against the FB(1) toxic effects by this detoxification procedure (p < 0.05)...
Rapid gut transit time and slow fecal isoflavone disappearance phenotype are associated with greater genistein bioavailability in womenYan Zheng
Department of Food Science and Human Nutrition, Iowa State University, Ames, IA 50011, USA
J Nutr 133:3110-6. 2003..Relatively rapid GTT coupled with a low fecal isoflavone disappearance phenotype as occurred in Asian but not Caucasian subjects produced greater genistein bioavailability, as reflected in urinary genistein excretion...
Glucuronides are the main isoflavone metabolites in womenYan Zhang
Department of Food Science and Human Nutrition, Iowa State University, Ames, IA 50011, USA
J Nutr 133:399-404. 2003..Because the glucuronide isoflavones predominate in vivo, these metabolites should not be overlooked as possible contributors to observed effects of isoflavones...
Quantification of the group B soyasaponins by high-performance liquid chromatographyJiang Hu
Department of Food Science and Human Nutrition, 2312 Food Science Building, Iowa State University, Ames, IA 50011, USA
J Agric Food Chem 50:2587-94. 2002..20 to 114.02 micromol/g. There was no apparent correlation between isoflavone and soyasaponin concentrations in the soy products examined...
Phytoestrogens in foodsPatricia A Murphy
Department of Food Science and Human Nutrition, Iowa State University, Ames, IA 50011, USA
Adv Food Nutr Res 44:195-246. 2002
A controlled 2-mo dietary fat reduction and soy food supplementation study in postmenopausal womenAnna H Wu
Department of Preventive Medicine, University of Southern California Norris Comprehensive Cancer Center, Keck School of Medicine, Los Angeles, CA 90089 9175, USA
Am J Clin Nutr 81:1133-41. 2005..Low intake of dietary fat and high intake of soy foods have been suggested to partly explain the lower breast cancer rates in Asia, perhaps because of lower endogenous estrogens...
