Paul Flakoll

Summary

Affiliation: Iowa State University
Country: USA

Publications

  1. ncbi Effect of beta-hydroxy-beta-methylbutyrate, arginine, and lysine supplementation on strength, functionality, body composition, and protein metabolism in elderly women
    Paul Flakoll
    Department of Health and Human Performance, Vanderbuilt University Medical Center, Nashville, Tennessee, USA
    Nutrition 20:445-51. 2004
  2. ncbi Postexercise protein supplementation improves health and muscle soreness during basic military training in Marine recruits
    Paul J Flakoll
    Center for Designing Food to Improve Nutrition, Dept of Food Science and Human Nutrition, Iowa State University, Ames 50011, USA
    J Appl Physiol 96:951-6. 2004
  3. ncbi Year-long changes in protein metabolism in elderly men and women supplemented with a nutrition cocktail of beta-hydroxy-beta-methylbutyrate (HMB), L-arginine, and L-lysine
    Shawn Baier
    Department of Food Science and Human Nutrition, Iowa State University, Ames, IA 50011, USA
    JPEN J Parenter Enteral Nutr 33:71-82. 2009
  4. ncbi Bioelectrical impedance vs air displacement plethysmography and dual-energy X-ray absorptiometry to determine body composition in patients with end-stage renal disease
    Paul J Flakoll
    Department of Surgery, Vanderbilt University Medical Center, Nashville, TN, USA
    JPEN J Parenter Enteral Nutr 28:13-21. 2004
  5. ncbi Exercise augments the acute anabolic effects of intradialytic parenteral nutrition in chronic hemodialysis patients
    Lara B Pupim
    Division of Nephrology, S-3223 MCN, Vanderbilt University Medical Center, 1161 21st Avenue South and Garland, Nashville, TN 37232-2372, USA
    Am J Physiol Endocrinol Metab 286:E589-97. 2004
  6. ncbi Glutamine supplementation increases postprandial energy expenditure and fat oxidation in humans
    Soh Iwashita
    Center for Designing Foods to Improve Nutrition, Department of Food Science and Human Nutrition, Iowa State University, Ames, IA 50011, USA
    JPEN J Parenter Enteral Nutr 30:76-80. 2006
  7. ncbi Recombinant human growth hormone improves muscle amino acid uptake and whole-body protein metabolism in chronic hemodialysis patients
    Lara B Pupim
    Department of Medicine, Division of Nephrology, Vanderbilt University Medical Center, Nashville, TN 37232-2372, USA
    Am J Clin Nutr 82:1235-43. 2005
  8. ncbi Increased muscle protein breakdown in chronic hemodialysis patients with type 2 diabetes mellitus
    Lara B Pupim
    Division of Nephrology and Division of Pediatric Endocrinology, Vanderbilt University School of Medicine, Nashville, Tennessee 37232, USA
    Kidney Int 68:1857-65. 2005
  9. ncbi Resistance exercise augments the acute anabolic effects of intradialytic oral nutritional supplementation
    Karen M Majchrzak
    Division of Nephrology, Vanderbilt University Medical Center, 1161 21st Ave South and Garland, S 3223 MCN, Nashville, TN 37232 2372, USA
    Nephrol Dial Transplant 23:1362-9. 2008
  10. ncbi Nutritional supplementation acutely increases albumin fractional synthetic rate in chronic hemodialysis patients
    Lara B Pupim
    Department of Medicine, Division of Nephrology, Vanderbilt University School of Medicine, Nashville, Tennessee, USA
    J Am Soc Nephrol 15:1920-6. 2004

Collaborators

  • T A Ikizler
  • Peter Stenvinkel
  • J Himmelfarb
  • Stephen N Davis
  • Greg J Welk
  • Rick L Sharp
  • Lara B Pupim
  • Shawn Baier
  • Karen M Majchrzak
  • Soh Iwashita
  • Deanna K Levenhagen
  • Darcy L Johannsen
  • Deanna Aftab Guy
  • Stephanie M Gustavson
  • E Patrick Donahue
  • Pengxiang She
  • Kayser Caglar
  • Raymond M Hakim
  • Naji Abumrad
  • Darcy Johannsen
  • Steven Nissen
  • John A Rathmacher
  • Catherine Mikus
  • Darleen Sandoval
  • Deanna L Aftab Guy
  • Takeo Ueda
  • M A Richardson
  • Kareem Jabbour
  • Hisamine Kobayashi
  • Phillip Williams
  • Chang Yu
  • Donna Tate
  • Alan D Cherrington
  • Ben Farmer
  • Makoto Nishizawa
  • Doss Neal
  • Chang An Chu
  • Ying Yang
  • Craig R Malloy
  • A Dean Sherry
  • Mark A Magnuson
  • Masakazu Shiota
  • Shawn C Burgess
  • Christopher Carr
  • Deanna Levenhagen
  • John R Brouillette
  • David J Maron
  • Myfanwy J Borel
  • Youming Peng
  • Michael G Carlson

Detail Information

Publications22

  1. ncbi Effect of beta-hydroxy-beta-methylbutyrate, arginine, and lysine supplementation on strength, functionality, body composition, and protein metabolism in elderly women
    Paul Flakoll
    Department of Health and Human Performance, Vanderbuilt University Medical Center, Nashville, Tennessee, USA
    Nutrition 20:445-51. 2004
    ....
  2. ncbi Postexercise protein supplementation improves health and muscle soreness during basic military training in Marine recruits
    Paul J Flakoll
    Center for Designing Food to Improve Nutrition, Dept of Food Science and Human Nutrition, Iowa State University, Ames 50011, USA
    J Appl Physiol 96:951-6. 2004
    ....
  3. ncbi Year-long changes in protein metabolism in elderly men and women supplemented with a nutrition cocktail of beta-hydroxy-beta-methylbutyrate (HMB), L-arginine, and L-lysine
    Shawn Baier
    Department of Food Science and Human Nutrition, Iowa State University, Ames, IA 50011, USA
    JPEN J Parenter Enteral Nutr 33:71-82. 2009
    ..Objectives: To determine whether supplementation of an amino acid cocktail daily for 1 year could improve the age-associated changes in protein turnover and lean body mass in elderly people...
  4. ncbi Bioelectrical impedance vs air displacement plethysmography and dual-energy X-ray absorptiometry to determine body composition in patients with end-stage renal disease
    Paul J Flakoll
    Department of Surgery, Vanderbilt University Medical Center, Nashville, TN, USA
    JPEN J Parenter Enteral Nutr 28:13-21. 2004
    ..Estimates of body water are fundamental for bioelectrical impedance analysis (BIA), which measures electrical resistance to estimate total body water and body composition...
  5. ncbi Exercise augments the acute anabolic effects of intradialytic parenteral nutrition in chronic hemodialysis patients
    Lara B Pupim
    Division of Nephrology, S-3223 MCN, Vanderbilt University Medical Center, 1161 21st Avenue South and Garland, Nashville, TN 37232-2372, USA
    Am J Physiol Endocrinol Metab 286:E589-97. 2004
    ..In conclusion, exercise in the presence of adequate nutritional supplementation has potential as a therapeutic intervention to blunt the loss of muscle mass in CHD patients...
  6. ncbi Glutamine supplementation increases postprandial energy expenditure and fat oxidation in humans
    Soh Iwashita
    Center for Designing Foods to Improve Nutrition, Department of Food Science and Human Nutrition, Iowa State University, Ames, IA 50011, USA
    JPEN J Parenter Enteral Nutr 30:76-80. 2006
    ..Consideration must be given to the potential that these postprandial changes in EE are related to glutamine-mediated changes in insulin action and consequently glucose disposal...
  7. ncbi Recombinant human growth hormone improves muscle amino acid uptake and whole-body protein metabolism in chronic hemodialysis patients
    Lara B Pupim
    Department of Medicine, Division of Nephrology, Vanderbilt University Medical Center, Nashville, TN 37232-2372, USA
    Am J Clin Nutr 82:1235-43. 2005
    ..CONCLUSION: rhGH improves whole-body protein homeostasis in chronic hemodialysis patients...
  8. ncbi Increased muscle protein breakdown in chronic hemodialysis patients with type 2 diabetes mellitus
    Lara B Pupim
    Division of Nephrology and Division of Pediatric Endocrinology, Vanderbilt University School of Medicine, Nashville, Tennessee 37232, USA
    Kidney Int 68:1857-65. 2005
    ..CONCLUSION: The results of this study demonstrate that CHD patients with T2DM under a suboptimal metabolic control display accelerated muscle protein loss compared with a matched group of non-DM CHD patients...
  9. ncbi Resistance exercise augments the acute anabolic effects of intradialytic oral nutritional supplementation
    Karen M Majchrzak
    Division of Nephrology, Vanderbilt University Medical Center, 1161 21st Ave South and Garland, S 3223 MCN, Nashville, TN 37232 2372, USA
    Nephrol Dial Transplant 23:1362-9. 2008
    ....
  10. ncbi Nutritional supplementation acutely increases albumin fractional synthetic rate in chronic hemodialysis patients
    Lara B Pupim
    Department of Medicine, Division of Nephrology, Vanderbilt University School of Medicine, Nashville, Tennessee, USA
    J Am Soc Nephrol 15:1920-6. 2004
    ..3 mg/kg fat-free mass/min; P < 0.05). IDPN is protein anabolic in the acute setting in CHD patients, as evidenced by significant concomitant increases in the fractional synthetic rate of albumin and whole-body protein synthesis...
  11. ncbi Urea space and total body water measurements by stable isotopes in patients with acute renal failure
    T Alp Ikizler
    Vanderbilt University Medical Center, Division of Nephrology, Nashville, Tennessee 37232 2372, USA
    Kidney Int 65:725-32. 2004
    ..However, these estimates of Vurea and TBW have not been validated by isotopic methods, considered as reference measurement standards...
  12. ncbi Effects of hyperglycemia, glucagon, and epinephrine on renal glucose release in the conscious dog
    Stephanie M Gustavson
    Department of Molecular Physiology and Biophysics and Diabetes Research and Training Center, Vanderbilt University, Nashville, TN, USA
    Metabolism 53:933-41. 2004
    ..Therefore, after an overnight fast in the conscious dog, the kidneys do not significantly contribute to overall glucose production or respond to glucagon or epinephrine...
  13. ncbi Mechanisms by which liver-specific PEPCK knockout mice preserve euglycemia during starvation
    Pengxiang She
    Department of Molecular Physiology and Biophysics, Vanderbilt University School of Medicine, Nashville, Tennessee 37232 0615, USA
    Diabetes 52:1649-54. 2003
    ....
  14. ncbi Protein homeostasis in chronic hemodialysis patients
    Lara B Pupim
    Department of Medicine, Division of Nephrology, Vanderbilt University Medical Center, Nashville, Tennessee 37232-2372, USA
    Curr Opin Clin Nutr Metab Care 7:89-95. 2004
    ..Despite this, chronic hemodialysis patients can still achieve anabolism when given adequate protein supplementation to meet the metabolic requirements of hemodialysis, and when adequate insulin is present...
  15. ncbi Postexercise protein intake enhances whole-body and leg protein accretion in humans
    Deanna K Levenhagen
    Department of Surgery, Vanderbilt University Medical Center, Nashville, TN 37232, USA
    Med Sci Sports Exerc 34:828-37. 2002
    ..CONCLUSIONS: These findings suggest that the availability of amino acids is more important than the availability of energy for postexercise repair and synthesis of muscle proteins...
  16. ncbi Intradialytic oral nutrition improves protein homeostasis in chronic hemodialysis patients with deranged nutritional status
    Lara B Pupim
    Department of Medicine, Division of Nephrology, Vanderbilt University Medical Center, Nashville, Tennessee 37232-2372, USA
    J Am Soc Nephrol 17:3149-57. 2006
    ..039 versus control], and -53 +/- 24 microg/100 ml per min for IDPN [P = 1.000 versus control and 0.039 versus PO]). Long-term studies using intradialytic oral supplementation are needed for CHD patients with deranged nutritional status...
  17. ncbi Intradialytic parenteral nutrition improves protein and energy homeostasis in chronic hemodialysis patients
    Lara B Pupim
    Department of Medicine, Division of Nephrology, Department of Surgery, and. Department of Biochemistry, Vanderbilt University Medical Center, Nashville, Tennessee 37232-2372, USA
    J Clin Invest 110:483-92. 2002
    ....
  18. ncbi Differences in daily energy expenditure in lean and obese women: the role of posture allocation
    Darcy L Johannsen
    Department of Food Science and Human Nutrition at Iowa State University, Ames, Iowa, USA
    Obesity (Silver Spring) 16:34-9. 2008
    ..The purposes of this study were to determine the RMR in lean and obese women controlling for FFM and investigate activity energy expenditure (AEE) and daily activity patterns in the two groups...
  19. ncbi Inflammatory signals associated with hemodialysis
    Kayser Caglar
    Department of Medicine, Division of Nephrology, Vanderbilt University Medical Center, 1161 21st Avenue South and Garland, S-3223 MCN Nashville, TN 37232-2372, USA
    Kidney Int 62:1408-16. 2002
    ..CONCLUSIONS: The results provide clear evidence of hemodialysis-induced inflammatory response. The process is most notable during the 2-hour post-hemodialysis period...
  20. ncbi Impact of glutamine supplementation on glucose homeostasis during and after exercise
    Soh Iwashita
    Center for Designing Foods to Improve Nutrition, Department of Food Science and Human Nutrition, Iowa State University, Ames, Iowa 50011, USA
    J Appl Physiol 99:1858-65. 2005
    ..05). In conclusion, glutamine availability modulates glucose homeostasis during and after exercise, which may have implications for postexercise recovery...
  21. ncbi Differing physiological effects of epinephrine in type 1 diabetes and nondiabetic humans
    Deanna Aftab Guy
    Division of Pediatric Endocrinology, Department of Pediatrics, Vanderbilt University School of Medicine, Nashville, TN 37232-6303, USA
    Am J Physiol Endocrinol Metab 288:E178-86. 2005
    ..Thus we conclude that there is a spectrum of significant in vivo physiological differences of epinephrine action at the liver, muscle, adipose tissue, pancreas, and cardiovascular system between T1DM and healthy subjects...
  22. ncbi Hemodialysis stimulates muscle and whole body protein loss and alters substrate oxidation
    T Alp Ikizler
    Division of Nephrology, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee 37232, USA
    Am J Physiol Endocrinol Metab 282:E107-16. 2002
    ....