Paul Flakoll

Summary

Affiliation: Iowa State University
Country: USA

Publications

  1. ncbi request reprint Effect of beta-hydroxy-beta-methylbutyrate, arginine, and lysine supplementation on strength, functionality, body composition, and protein metabolism in elderly women
    Paul Flakoll
    Department of Health and Human Performance, Vanderbuilt University Medical Center, Nashville, Tennessee, USA
    Nutrition 20:445-51. 2004
  2. ncbi request reprint Postexercise protein supplementation improves health and muscle soreness during basic military training in Marine recruits
    Paul J Flakoll
    Center for Designing Food to Improve Nutrition, Dept of Food Science and Human Nutrition, Iowa State University, Ames 50011, USA
    J Appl Physiol 96:951-6. 2004
  3. doi request reprint Year-long changes in protein metabolism in elderly men and women supplemented with a nutrition cocktail of beta-hydroxy-beta-methylbutyrate (HMB), L-arginine, and L-lysine
    Shawn Baier
    Department of Food Science and Human Nutrition, Iowa State University, Ames, IA 50011, USA
    JPEN J Parenter Enteral Nutr 33:71-82. 2009
  4. ncbi request reprint Bioelectrical impedance vs air displacement plethysmography and dual-energy X-ray absorptiometry to determine body composition in patients with end-stage renal disease
    Paul J Flakoll
    Department of Surgery, Vanderbilt University Medical Center, Nashville, TN, USA
    JPEN J Parenter Enteral Nutr 28:13-21. 2004
  5. ncbi request reprint Exercise augments the acute anabolic effects of intradialytic parenteral nutrition in chronic hemodialysis patients
    Lara B Pupim
    Division of Nephrology, S 3223 MCN, Vanderbilt University Medical Center, 1161 21st Avenue South and Garland, Nashville, TN 37232 2372, USA
    Am J Physiol Endocrinol Metab 286:E589-97. 2004
  6. ncbi request reprint Glutamine supplementation increases postprandial energy expenditure and fat oxidation in humans
    Soh Iwashita
    Center for Designing Foods to Improve Nutrition, Department of Food Science and Human Nutrition, Iowa State University, Ames, IA 50011, USA
    JPEN J Parenter Enteral Nutr 30:76-80. 2006
  7. ncbi request reprint Recombinant human growth hormone improves muscle amino acid uptake and whole-body protein metabolism in chronic hemodialysis patients
    Lara B Pupim
    Department of Medicine, Division of Nephrology, Vanderbilt University Medical Center, Nashville, TN 37232 2372, USA
    Am J Clin Nutr 82:1235-43. 2005
  8. ncbi request reprint Increased muscle protein breakdown in chronic hemodialysis patients with type 2 diabetes mellitus
    Lara B Pupim
    Division of Nephrology and Division of Pediatric Endocrinology, Vanderbilt University School of Medicine, Nashville, Tennessee 37232, USA
    Kidney Int 68:1857-65. 2005
  9. ncbi request reprint Resistance exercise augments the acute anabolic effects of intradialytic oral nutritional supplementation
    Karen M Majchrzak
    Division of Nephrology, Vanderbilt University Medical Center, 1161 21st Ave South and Garland, S 3223 MCN, Nashville, TN 37232 2372, USA
    Nephrol Dial Transplant 23:1362-9. 2008
  10. ncbi request reprint Nutritional supplementation acutely increases albumin fractional synthetic rate in chronic hemodialysis patients
    Lara B Pupim
    Department of Medicine, Division of Nephrology, Vanderbilt University School of Medicine, Nashville, Tennessee, USA
    J Am Soc Nephrol 15:1920-6. 2004

Collaborators

  • T A Ikizler
  • Peter Stenvinkel
  • J Himmelfarb
  • Stephen N Davis
  • Greg J Welk
  • Rick L Sharp
  • Lara B Pupim
  • Shawn Baier
  • Karen M Majchrzak
  • Soh Iwashita
  • Deanna K Levenhagen
  • Darcy L Johannsen
  • Deanna Aftab Guy
  • Stephanie M Gustavson
  • E Patrick Donahue
  • Pengxiang She
  • Raymond M Hakim
  • Kayser Caglar
  • Darcy Johannsen
  • Naji Abumrad
  • Steven Nissen
  • John A Rathmacher
  • Catherine Mikus
  • Darleen Sandoval
  • M A Richardson
  • Chang Yu
  • Deanna L Aftab Guy
  • Phillip Williams
  • Kareem Jabbour
  • Hisamine Kobayashi
  • Takeo Ueda
  • Donna Tate
  • Ying Yang
  • Makoto Nishizawa
  • Doss Neal
  • Chang An Chu
  • Ben Farmer
  • Alan D Cherrington
  • Shawn C Burgess
  • Craig R Malloy
  • Mark A Magnuson
  • A Dean Sherry
  • Masakazu Shiota
  • Deanna Levenhagen
  • Youming Peng
  • Christopher Carr
  • David J Maron
  • John R Brouillette
  • Myfanwy J Borel
  • Michael G Carlson

Detail Information

Publications22

  1. ncbi request reprint Effect of beta-hydroxy-beta-methylbutyrate, arginine, and lysine supplementation on strength, functionality, body composition, and protein metabolism in elderly women
    Paul Flakoll
    Department of Health and Human Performance, Vanderbuilt University Medical Center, Nashville, Tennessee, USA
    Nutrition 20:445-51. 2004
    ....
  2. ncbi request reprint Postexercise protein supplementation improves health and muscle soreness during basic military training in Marine recruits
    Paul J Flakoll
    Center for Designing Food to Improve Nutrition, Dept of Food Science and Human Nutrition, Iowa State University, Ames 50011, USA
    J Appl Physiol 96:951-6. 2004
    ....
  3. doi request reprint Year-long changes in protein metabolism in elderly men and women supplemented with a nutrition cocktail of beta-hydroxy-beta-methylbutyrate (HMB), L-arginine, and L-lysine
    Shawn Baier
    Department of Food Science and Human Nutrition, Iowa State University, Ames, IA 50011, USA
    JPEN J Parenter Enteral Nutr 33:71-82. 2009
    ..Objectives: To determine whether supplementation of an amino acid cocktail daily for 1 year could improve the age-associated changes in protein turnover and lean body mass in elderly people...
  4. ncbi request reprint Bioelectrical impedance vs air displacement plethysmography and dual-energy X-ray absorptiometry to determine body composition in patients with end-stage renal disease
    Paul J Flakoll
    Department of Surgery, Vanderbilt University Medical Center, Nashville, TN, USA
    JPEN J Parenter Enteral Nutr 28:13-21. 2004
    ..Estimates of body water are fundamental for bioelectrical impedance analysis (BIA), which measures electrical resistance to estimate total body water and body composition...
  5. ncbi request reprint Exercise augments the acute anabolic effects of intradialytic parenteral nutrition in chronic hemodialysis patients
    Lara B Pupim
    Division of Nephrology, S 3223 MCN, Vanderbilt University Medical Center, 1161 21st Avenue South and Garland, Nashville, TN 37232 2372, USA
    Am J Physiol Endocrinol Metab 286:E589-97. 2004
    ..In conclusion, exercise in the presence of adequate nutritional supplementation has potential as a therapeutic intervention to blunt the loss of muscle mass in CHD patients...
  6. ncbi request reprint Glutamine supplementation increases postprandial energy expenditure and fat oxidation in humans
    Soh Iwashita
    Center for Designing Foods to Improve Nutrition, Department of Food Science and Human Nutrition, Iowa State University, Ames, IA 50011, USA
    JPEN J Parenter Enteral Nutr 30:76-80. 2006
    ..Glutamine interacts with insulin-mediated glucose disposal, which is a component of the increase in energy expenditure (EE) after a meal. The study aim was to examine if glutamine supplementation alters postmeal nutrient oxidation...
  7. ncbi request reprint Recombinant human growth hormone improves muscle amino acid uptake and whole-body protein metabolism in chronic hemodialysis patients
    Lara B Pupim
    Department of Medicine, Division of Nephrology, Vanderbilt University Medical Center, Nashville, TN 37232 2372, USA
    Am J Clin Nutr 82:1235-43. 2005
    ..Pharmacologic doses of recombinant human growth hormone (rhGH) constitute another potential anabolic therapy in chronic hemodialysis patients...
  8. ncbi request reprint Increased muscle protein breakdown in chronic hemodialysis patients with type 2 diabetes mellitus
    Lara B Pupim
    Division of Nephrology and Division of Pediatric Endocrinology, Vanderbilt University School of Medicine, Nashville, Tennessee 37232, USA
    Kidney Int 68:1857-65. 2005
    ..The presence of diabetes mellitus (DM) in chronic hemodialysis (CHD) patients has potential to increase body protein losses and muscle wasting...
  9. ncbi request reprint Resistance exercise augments the acute anabolic effects of intradialytic oral nutritional supplementation
    Karen M Majchrzak
    Division of Nephrology, Vanderbilt University Medical Center, 1161 21st Ave South and Garland, S 3223 MCN, Nashville, TN 37232 2372, USA
    Nephrol Dial Transplant 23:1362-9. 2008
    ....
  10. ncbi request reprint Nutritional supplementation acutely increases albumin fractional synthetic rate in chronic hemodialysis patients
    Lara B Pupim
    Department of Medicine, Division of Nephrology, Vanderbilt University School of Medicine, Nashville, Tennessee, USA
    J Am Soc Nephrol 15:1920-6. 2004
    ..3 mg/kg fat-free mass/min; P < 0.05). IDPN is protein anabolic in the acute setting in CHD patients, as evidenced by significant concomitant increases in the fractional synthetic rate of albumin and whole-body protein synthesis...
  11. ncbi request reprint Urea space and total body water measurements by stable isotopes in patients with acute renal failure
    T Alp Ikizler
    Vanderbilt University Medical Center, Division of Nephrology, Nashville, Tennessee 37232 2372, USA
    Kidney Int 65:725-32. 2004
    ..However, these estimates of Vurea and TBW have not been validated by isotopic methods, considered as reference measurement standards...
  12. ncbi request reprint Effects of hyperglycemia, glucagon, and epinephrine on renal glucose release in the conscious dog
    Stephanie M Gustavson
    Department of Molecular Physiology and Biophysics and Diabetes Research and Training Center, Vanderbilt University, Nashville, TN, USA
    Metabolism 53:933-41. 2004
    ..Therefore, after an overnight fast in the conscious dog, the kidneys do not significantly contribute to overall glucose production or respond to glucagon or epinephrine...
  13. ncbi request reprint Mechanisms by which liver-specific PEPCK knockout mice preserve euglycemia during starvation
    Pengxiang She
    Department of Molecular Physiology and Biophysics, Vanderbilt University School of Medicine, Nashville, Tennessee 37232 0615, USA
    Diabetes 52:1649-54. 2003
    ....
  14. ncbi request reprint Protein homeostasis in chronic hemodialysis patients
    Lara B Pupim
    Department of Medicine, Division of Nephrology, Vanderbilt University Medical Center, Nashville, Tennessee 37232 2372, USA
    Curr Opin Clin Nutr Metab Care 7:89-95. 2004
    ..The purpose of this review is to discuss recent advances in the understanding of abnormalities in protein homeostasis in chronic hemodialysis patients...
  15. ncbi request reprint Postexercise protein intake enhances whole-body and leg protein accretion in humans
    Deanna K Levenhagen
    Department of Surgery, Vanderbilt University Medical Center, Nashville, TN 37232, USA
    Med Sci Sports Exerc 34:828-37. 2002
    ..The purpose of this study was to determine the potential of postexercise nutrient intake to enhance the recovery of whole-body and skeletal muscle protein homeostasis in humans...
  16. ncbi request reprint Intradialytic oral nutrition improves protein homeostasis in chronic hemodialysis patients with deranged nutritional status
    Lara B Pupim
    Department of Medicine, Division of Nephrology, Vanderbilt University Medical Center, Nashville, Tennessee 37232 2372, USA
    J Am Soc Nephrol 17:3149-57. 2006
    ..039 versus control], and -53 +/- 24 microg/100 ml per min for IDPN [P = 1.000 versus control and 0.039 versus PO]). Long-term studies using intradialytic oral supplementation are needed for CHD patients with deranged nutritional status...
  17. pmc Intradialytic parenteral nutrition improves protein and energy homeostasis in chronic hemodialysis patients
    Lara B Pupim
    Department of Medicine, Division of Nephrology, Department of Surgery, and Department of Biochemistry, Vanderbilt University Medical Center, Nashville, Tennessee 37232 2372, USA
    J Clin Invest 110:483-92. 2002
    ....
  18. doi request reprint Differences in daily energy expenditure in lean and obese women: the role of posture allocation
    Darcy L Johannsen
    Department of Food Science and Human Nutrition at Iowa State University, Ames, Iowa, USA
    Obesity (Silver Spring) 16:34-9. 2008
    ..The purposes of this study were to determine the RMR in lean and obese women controlling for FFM and investigate activity energy expenditure (AEE) and daily activity patterns in the two groups...
  19. ncbi request reprint Inflammatory signals associated with hemodialysis
    Kayser Caglar
    Department of Medicine, Division of Nephrology, Vanderbilt University Medical Center, 1161 21st Avenue South and Garland, S 3223 MCN Nashville, TN 37232 2372, USA
    Kidney Int 62:1408-16. 2002
    ..Earlier studies did not provide clear-cut evidence of the potential contribution of the hemodialysis procedure to inflammation, as assessed by markers of inflammation such as cytokine levels and acute-phase protein production...
  20. ncbi request reprint Impact of glutamine supplementation on glucose homeostasis during and after exercise
    Soh Iwashita
    Center for Designing Foods to Improve Nutrition, Department of Food Science and Human Nutrition, Iowa State University, Ames, Iowa 50011, USA
    J Appl Physiol 99:1858-65. 2005
    ..05). In conclusion, glutamine availability modulates glucose homeostasis during and after exercise, which may have implications for postexercise recovery...
  21. ncbi request reprint Differing physiological effects of epinephrine in type 1 diabetes and nondiabetic humans
    Deanna Aftab Guy
    Division of Pediatric Endocrinology, Department of Pediatrics, Vanderbilt University School of Medicine, Nashville, TN 37232 6303, USA
    Am J Physiol Endocrinol Metab 288:E178-86. 2005
    ..Thus we conclude that there is a spectrum of significant in vivo physiological differences of epinephrine action at the liver, muscle, adipose tissue, pancreas, and cardiovascular system between T1DM and healthy subjects...
  22. ncbi request reprint Hemodialysis stimulates muscle and whole body protein loss and alters substrate oxidation
    T Alp Ikizler
    Division of Nephrology, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee 37232, USA
    Am J Physiol Endocrinol Metab 282:E107-16. 2002
    ....