Jeffrey J Essner

Summary

Affiliation: Iowa State University
Country: USA

Publications

  1. pmc Use of RecA fusion proteins to induce genomic modifications in zebrafish
    Hsin Kai Liao
    Department of Genetics, Iowa State University, Ames, IA 50011, USA
    Nucleic Acids Res 39:4166-79. 2011
  2. pmc Transient axonal glycoprotein-1 (TAG-1) and laminin-alpha1 regulate dynamic growth cone behaviors and initial axon direction in vivo
    Marc A Wolman
    Department of Zoology, and Neuroscience Training Program, University of Wisconsin, Madison, Wisconsin 53706, USA
    Neural Dev 3:6. 2008
  3. ncbi request reprint Syndecan-2
    Jeffrey J Essner
    Discovery Genomics Inc, 614 McKinley Place N E, Minneapolis, MN 55413, USA
    Int J Biochem Cell Biol 38:152-6. 2006
  4. pmc Moesin1 and Ve-cadherin are required in endothelial cells during in vivo tubulogenesis
    Ying Wang
    Department of Genetics, Development and Cell Biology, Iowa State University, Ames, IA 50011, USA
    Development 137:3119-28. 2010
  5. pmc Tol2 gene trap integrations in the zebrafish amyloid precursor protein genes appa and aplp2 reveal accumulation of secreted APP at the embryonic veins
    Hsin Kai Liao
    Department of Genetics, Development and Cell Biology, Iowa State University, Ames, Iowa 50011, USA
    Dev Dyn 241:415-25. 2012
  6. pmc Somatic mutagenesis with a Sleeping Beauty transposon system leads to solid tumor formation in zebrafish
    Maura McGrail
    Department of Genetics, Development and Cell Biology, Iowa State University, Ames, Iowa, United States of America
    PLoS ONE 6:e18826. 2011
  7. ncbi request reprint Expression of the zebrafish CD133/prominin1 genes in cellular proliferation zones in the embryonic central nervous system and sensory organs
    Maura McGrail
    Department of Genetics, Development and Cell Biology, Iowa State University, Ames, Iowa 50011, USA
    Dev Dyn 239:1849-57. 2010
  8. pmc SCORE imaging: specimen in a corrected optical rotational enclosure
    Andrew M Petzold
    Comparative and Molecular Biology, University of Minnesota, Minneapolis, Minnesota, USA
    Zebrafish 7:149-54. 2010
  9. doi request reprint A gap junction connexin is required in the vertebrate left-right organizer
    Julia M Hatler
    Department of Genetics, Cell Biology and Development, University of Minnesota, 420 Washington Ave SE, MCB 6 150, Minneapolis, MN 55455, USA
    Dev Biol 336:183-91. 2009
  10. ncbi request reprint Expression of VE-cadherin in zebrafish embryos: a new tool to evaluate vascular development
    Jon D Larson
    Discovery Genomics, Incorporated, Minneapolis, Minnesota, USA
    Dev Dyn 231:204-13. 2004

Research Grants

  1. ANGIOGENESIS TARGETS FOR THERAPEUTIC DEVELOPMENT
    JEFFREY ESSNER; Fiscal Year: 2004

Collaborators

Detail Information

Publications11

  1. pmc Use of RecA fusion proteins to induce genomic modifications in zebrafish
    Hsin Kai Liao
    Department of Genetics, Iowa State University, Ames, IA 50011, USA
    Nucleic Acids Res 39:4166-79. 2011
    ..Our data support a model whereby NLS-RecA-Gal4 DNA filaments bind to complementary target sites on chromatin and stall DNA replication forks, resulting in a DNA DSB...
  2. pmc Transient axonal glycoprotein-1 (TAG-1) and laminin-alpha1 regulate dynamic growth cone behaviors and initial axon direction in vivo
    Marc A Wolman
    Department of Zoology, and Neuroscience Training Program, University of Wisconsin, Madison, Wisconsin 53706, USA
    Neural Dev 3:6. 2008
    ..We have taken advantage of the unique features of the zebrafish embryo to visualize dynamic growth cone behaviors and analyze guidance mechanisms of axons emerging from a central brain nucleus in vivo...
  3. ncbi request reprint Syndecan-2
    Jeffrey J Essner
    Discovery Genomics Inc, 614 McKinley Place N E, Minneapolis, MN 55413, USA
    Int J Biochem Cell Biol 38:152-6. 2006
    ..This unique combination of activities suggests that syndecan-2 can function as a potential drug target for the development of multi-functional, anti-cancer therapeutics...
  4. pmc Moesin1 and Ve-cadherin are required in endothelial cells during in vivo tubulogenesis
    Ying Wang
    Department of Genetics, Development and Cell Biology, Iowa State University, Ames, IA 50011, USA
    Development 137:3119-28. 2010
    ..We suggest that Ve-cadherin and Moesin1 function to establish and maintain apical/basal polarity during multicellular lumen formation in the ISVs...
  5. pmc Tol2 gene trap integrations in the zebrafish amyloid precursor protein genes appa and aplp2 reveal accumulation of secreted APP at the embryonic veins
    Hsin Kai Liao
    Department of Genetics, Development and Cell Biology, Iowa State University, Ames, Iowa 50011, USA
    Dev Dyn 241:415-25. 2012
    ..The transposon integrations are predicted to disrupt the appa and aplp2 genes to primarily produce secreted ectodomains of the corresponding proteins that are fused to RFP...
  6. pmc Somatic mutagenesis with a Sleeping Beauty transposon system leads to solid tumor formation in zebrafish
    Maura McGrail
    Department of Genetics, Development and Cell Biology, Iowa State University, Ames, Iowa, United States of America
    PLoS ONE 6:e18826. 2011
    ..The zebrafish T2/OncZ cancer model will be useful for identifying novel and conserved genetic drivers of human cancers...
  7. ncbi request reprint Expression of the zebrafish CD133/prominin1 genes in cellular proliferation zones in the embryonic central nervous system and sensory organs
    Maura McGrail
    Department of Genetics, Development and Cell Biology, Iowa State University, Ames, Iowa 50011, USA
    Dev Dyn 239:1849-57. 2010
    ..Based on these analyses, the zebrafish prominin1 genes will be useful markers for examining proliferating cell populations in adult organs, tissues, and tumors...
  8. pmc SCORE imaging: specimen in a corrected optical rotational enclosure
    Andrew M Petzold
    Comparative and Molecular Biology, University of Minnesota, Minneapolis, Minnesota, USA
    Zebrafish 7:149-54. 2010
    ..The method described here could be applied to chemical genetic screening and other related high-throughput methods within the fish community and among other scientific fields...
  9. doi request reprint A gap junction connexin is required in the vertebrate left-right organizer
    Julia M Hatler
    Department of Genetics, Cell Biology and Development, University of Minnesota, 420 Washington Ave SE, MCB 6 150, Minneapolis, MN 55455, USA
    Dev Biol 336:183-91. 2009
    ..4 during L-R patterning. This is the first report linking connexin function in the ciliated, node-like cells of KV with normal L-R axis development...
  10. ncbi request reprint Expression of VE-cadherin in zebrafish embryos: a new tool to evaluate vascular development
    Jon D Larson
    Discovery Genomics, Incorporated, Minneapolis, Minnesota, USA
    Dev Dyn 231:204-13. 2004
    ..This loss can be restored in embryos supplemented with either zebrafish or human VEGF-A, the latter indicating that genes crucial to angiogenesis have highly conserved functional activities in vertebrates...
  11. pmc Zebrafish RNase T2 genes and the evolution of secretory ribonucleases in animals
    Melissa S Hillwig
    Interdepartmental Genetics Graduate Program, Iowa State University, Ames, IA 50011, USA
    BMC Evol Biol 9:170. 2009
    ..Interestingly, in vertebrates most of the biological roles of plant RNase T2 proteins are carried out by members of a different family, RNase A. Still, RNase T2 proteins are conserved in these animals..

Research Grants1

  1. ANGIOGENESIS TARGETS FOR THERAPEUTIC DEVELOPMENT
    JEFFREY ESSNER; Fiscal Year: 2004
    ..Based on these tests, the highest priority gene(s) will be used for future testing in mammalian tissue culture and mouse tumor models for development as therapeutics for cancer treatment. ..