Research Topics
| L L AndersonSummaryAffiliation: Iowa State University Country: USA Publications
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Detail Information
Publications
Nanobiology and physiology of growth hormone secretionLloyd L Anderson
Department of Animal Science, Iowa State University, Ames, IA 50011, USA
Exp Biol Med (Maywood) 237:126-42. 2012..Other peptides/proteins can influence GH secretion, particularly in species of non-mammalian vertebrates...
Growth hormone secretion: molecular and cellular mechanisms and in vivo approachesLloyd L Anderson
Department of Animal Science, Iowa State University, Ames, Iowa 50011, USA
Exp Biol Med (Maywood) 229:291-302. 2004..The GH-containing secretory granules are moved close to the cell surface. There is then transient fusion of the secretory granules with the fusion pores in the multiple secretory pits in the somatotrope cell surface...
Discovery of a new cellular structure--the porosome: elucidation of the molecular mechanism of secretionLloyd L Anderson
Department of Animal Science, College of Agriculture, Iowa State University, Ames, IA 50011-3150, USA
Cell Biol Int 28:3-5. 2004
Discovery of the 'porosome'; the universal secretory machinery in cellsL L Anderson
Section of Physiology, Department of Animal Science, College of Agriculture and Department of Biomedical Sciences, College of Veterinary Medicine, Iowa State University, 2356 Kildee Hall, Ames, IA 50011 3150, USA
J Cell Mol Med 10:126-31. 2006..In this minireview, the monumental discovery of the porosome, a new cellular structure at the cell plasma membrane, is briefly discussed...
Physiology of ghrelin and related peptidesL L Anderson
Department of Animal Science, College of Agriculture, Iowa State University, Ames, IA 50011 3150, USA
Domest Anim Endocrinol 29:111-44. 2005..This process for GH release from porcine somatotrophs was revealed by atomic force microscopy (AFM), transmission electron microscopy (TEM) and immunohistochemical distribution of the cells in pituitary during stages of development...
Long-term growth after hypophyseal stalk transection and hypophysectomy of beef calvesL L Anderson
Department of Animal Science, Iowa State University, Ames 50011 3150, USA
Endocrinology 140:2405-14. 1999..Growth was abolished after hypophysectomy of immature calves in which circulating GH and TSH was undetectable...
Pregnancy, parturition, and lactation in hypophyseal stalk-transected beef heifersL L Anderson
Neuroscience Program, Department of Animal Science, Iowa State University, Ames, Iowa 50011, U S A
J Endocrinol 163:463-75. 1999..The results suggest that PRL, GH and possibly placental lactogen are luteotropic during pregnancy in cattle...
Mechanism of action of the growth hormone secretagogue, L-692,585, on isolated porcine somatotropesA Glavaski-Joksimovic
Neuroscience Program, Department of Biomedical Sciences, College of Veterinary Medicine, Iowa State University, 1098 Veterinary Medicine Building, Ames, Iowa 50011, USA
J Endocrinol 175:625-36. 2002....
Lack of estrogenic or antiestrogenic actions of soy isoflavones in an avian model: the Japanese quailK W Wilhelms
Interdepartmental Toxicology Program, Iowa State University, Ames 50011, USA
Poult Sci 85:1885-9. 2006..The present results suggest that isoflavones may exert modest endocrine disruptor-like effects on reproduction in male, but not female, quail...
Intracerebroventricular and intravenous administration of growth hormone secretagogue L-692,585, somatostatin, neuropeptide Y and galanin in pig: dose-dependent effects on growth hormone secretionS J Cho
Department of Animal Science, Iowa State University, Ames, IA 50011, USA
Comp Biochem Physiol C Toxicol Pharmacol 151:412-9. 2010..The pharmacological actions by icv administration indicate that the GH secretagogue and neuropeptides act at the level of both porcine pituitary and hypothalamus...
Mifepristone (RU 486) induces parturition in primiparous beef heifers and reduces incidence of dystociaB J Dlamini
Department of Animal Science, Iowa State University, Ames 50011 3150, USA
J Anim Sci 73:3421-6. 1995..Hormone treatment promotes calving ease with a markedly reduced incidence of the detrimental effects of dystocia, which may be a serious problem in first-calf heifers...
Evaluation of corn furan fatty acid putative endocrine disruptors on reproductive performance in adult female chickensK W Wilhelms
Interdepartmental Toxicology Program, Department of Animal Science, Iowa State University, Ames 50011, USA
Poult Sci 85:1795-7. 2006..The present data do not suggest that furan fatty acids are a cause of concern to the poultry industry...
Lack of effects of atrazine on estrogen-responsive organs and circulating hormone concentrations in sexually immature female Japanese quail (Coturnix coturnix japonica)K W Wilhelms
Interdepartmental Toxicology Program, Iowa State University, Ames, IA 50011, United States
Chemosphere 65:674-81. 2006..001 to 1000 ppm) and systemically administered atrazine had no effect on circulating concentrations of luteinizing hormone (LH). The present studies provide evidence for a lack of general or reproductive toxicity of atrazine in birds...
Effects of growth hormone-releasing factor and somatostatin on growth hormone secretion in hypophysial stalk-transected beef calvesC A Plouzek
Department of Animal Science, Iowa State University, Ames 50011
Proc Soc Exp Biol Med 189:158-67. 1988..These results indicate that HST calves responded to exogenous GHRF with an abrupt increase in plasma GH, but GH response to GHRF during SRIH infusion was greatly inhibited...
Functional and phylogenetic analyses of a melanocortin-4 receptor mutation in domestic pigsK-S Kim
Department of Animal Science and Center for Integrated Animal Genomics, Iowa State University, Ames, IA 50011, USA
Domest Anim Endocrinol 26:75-86. 2004....
Relaxin-induced expression of Fos in the forebrain of the late pregnant ratP A Heine
Department of Veterinary Anatomy, Iowa State University, Ames 50011, USA
Neuroendocrinology 66:38-46. 1997....
Exogenous glucagon effects on health and reproductive performance of lactating dairy cows with mild fatty liverG Bobe
Nutritional Physiology Group, Department of Animal Science, Iowa State University, 313 Kildee Hall, Ames, IA 50011 3150, USA
Anim Reprod Sci 102:194-207. 2007..From these results, we suggest that mild fatty liver is detrimental to health and reproduction of dairy cows and, furthermore, that exogenous glucagon decreases some of these detrimental effects...
Stimulatory effect of ghrelin on isolated porcine somatotropesAleksandra Glavaski-Joksimovic
Neuroscience Program, Department of Biomedical Sciences, College of Veterinary Medicine, Iowa State University, Ames, Iowa 50011, USA
Neuroendocrinology 77:367-79. 2003..Our results suggest that the actions of ghrelin and synthetic GHS closely parallel each other, in a manner that is consistent with an increase of hormone secretion...
In ovo exposure to a triazine herbicide: effects of atrazine on circulating reproductive hormones and gonadal histology in young Japanese quailK W Wilhelms
Interdepartmental Toxicology Program, Iowa State University, Ames, Iowa 50011, USA
Arch Environ Contam Toxicol 51:117-22. 2006..However, no evidence is presented that atrazine induces feminization of the testis in male quail...
Neonatal Meishan pigs show POU1F1 genotype effects on plasma GH and PRL concentrationH S Sun
Department of Animal Science, Iowa State University, Ames, IA 50011-3150, USA
Anim Reprod Sci 69:223-37. 2002..Results from this study add to our understanding of the role of POU1F1 in controlling pig development and reproduction...
Number of secretory vesicles in growth hormone cells of the pituitary remains unchanged after secretionJin-Sook Lee
Iowa State University, 2356 Kildee Hall, Ames, IA 50011-3150, USA
Exp Biol Med (Maywood) 229:632-9. 2004..These results are consistent with a mechanism that, after stimulation of secretion, vesicles transiently dock and fuse at the fusion pore to release vesicular contents...
Subpopulations of somatotropes with differing intracellular calcium concentration responses to secretagoguesColin G Scanes
Department of Animal Science, Iowa State University, Ames, Iowa, USA
Neuroendocrinology 85:221-31. 2007..It is concluded that there are subsets of the somatotrope population in the anterior pituitary gland with differences in their ability to respond to various secretagogues...
Immunocytochemical distribution of somatotrophs in porcine anterior pituitaryJin-Sook Lee
Department of Animal Science, College of Agriculture, Iowa State University, 2356 Kildee Hall, Ames, IA 50011-3150, USA
Histochem Cell Biol 122:571-7. 2004..From these results, we suggest that there may be regional specificity of cellular differentiation and transformation to facilitate GH secretion to meet the need for endocrine regulation as the animal ages...
Structure and dynamics of the fusion pores in live GH-secreting cells revealed using atomic force microscopySang-Joon Cho
Department of Physiology, Wayne State University, School of Medicine, Detroit, Michigan 48201, USA
Endocrinology 143:1144-8. 2002..This study documents for the first time the presence of these structures and their involvement in secretions in a neuroendocrine cell...
