Research Topics
| D AlekelSummaryAffiliation: Iowa State University Country: USA Publications
Research Grants
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Detail Information
Publications
Lifestyle and biologic contributors to proximal femur bone mineral density and hip axis length in two distinct ethnic groups of premenopausal womenD L Alekel
Department of Food Science and Human Nutrition, Iowa State University, Ames, Iowa, USA
Osteoporos Int 9:327-38. 1999..These results suggest that a clinical trial to increase BMD and reduce osteoporotic risk is warranted in this ethnic group of premenopausal women...
The soy isoflavones for reducing bone loss (SIRBL) study: a 3-y randomized controlled trial in postmenopausal womenD Lee Alekel
Nutrition and Wellness Research Center, Department of Food Science and Human Nutrition, Iowa State University, Ames, IA 50010 8281, USA
Am J Clin Nutr 91:218-30. 2010..Our previous study indicated that soy protein with isoflavones lessened lumbar spine bone loss in midlife women...- Frame size, ethnicity, lifestyle, and biologic contributors to areal and volumetric lumbar spine bone mineral density in Indian/Pakistani and American Caucasian premenopausal womenD Lee Alekel
Department of Food Science and Human Nutrition, Iowa State University, Ames, Iowa 50011, USA
J Clin Densitom 5:175-86. 2002..Upon accounting for frame size using regression, much variability in BMD, aBMD, and vBMD was explained by lifestyle and biologic factors, not by ethnicity... - Isoflavone-rich soy protein isolate attenuates bone loss in the lumbar spine of perimenopausal womenD L Alekel
Department of Food Science and Human Nutrition, Human Metabolic Unit, Center for Designing Foods to Improve Nutrition, the Department of Statistics, Iowa State University, Ames 50011 1120, USA
Am J Clin Nutr 72:844-52. 2000..No published studies have directly examined the effect of soy protein with isoflavones on bone or bone turnover in perimenopausal women... - Serum 25-hydroxyvitamin D is related to indicators of overall physical fitness in healthy postmenopausal womenJeanne W Stewart
Department of Food Science and Human Nutrition, Iowa State University, Ames, IA 50010 8281, USA
Menopause 16:1093-101. 2009..We hypothesized that serum 25-hydroxyvitamin D [25(OH)D] is related to physical fitness indices (androidal fat, whole body lean mass, balance, strength) in healthy postmenopausal women... - Isoflavone-rich soy protein prevents loss of hip lean mass but does not prevent the shift in regional fat distribution in perimenopausal womenLaura E Moeller
Roy J. and Lucille A. Carver College of Medicine, University of Iowa, Iowa City, Iowa, USA
Menopause 10:322-31. 2003..047) contributed to the gain in hip lean mass. CONCLUSIONS: Gain in hip lean mass was greater (P = 0.014) in SPI+ than other groups, but SPI+ did not reduce the disease-promoting menopausal shift in regional fat mass... - Effects of soy isoflavones and phytate on homocysteine, C-reactive protein, and iron status in postmenopausal womenLaura N Hanson
Department of Food Science and Human Nutrition, Iowa State University, Ames, IA 50011, USA
Am J Clin Nutr 84:774-80. 2006..9%, P = 0.003) to the overall variance in tHcy. CONCLUSION: Consuming phytate-rich foods and maintaining a healthy weight may reduce atherosclerotic CVD risk factors in postmenopausal women... - Rapid gut transit time and slow fecal isoflavone disappearance phenotype are associated with greater genistein bioavailability in womenYan Zheng
Department of Food Science and Human Nutrition, Iowa State University, Ames, IA 50011, USA
J Nutr 133:3110-6. 2003..Relatively rapid GTT coupled with a low fecal isoflavone disappearance phenotype as occurred in Asian but not Caucasian subjects produced greater genistein bioavailability, as reflected in urinary genistein excretion... - Centrally located body fat is related to appetitive hormones in healthy postmenopausal womenLaura M Ritland
Human Metabolic Unit, Department of Food Science and Human Nutrition, Iowa State University, 1115 Human Nutritional Sciences Building, Ames, Iowa 50011, USA
Eur J Endocrinol 158:889-97. 2008..This study examined whether centrally located fat and/or overall adiposity were related to these appetitive hormones in healthy postmenopausal women... - Relationship of circulating total homocysteine and C-reactive protein to trabecular bone in postmenopausal womenShilpa N Bhupathiraju
Department of Food Science and Human Nutrition, Human Metabolic Unit, Center for Designing Foods to Improve Nutrition, Iowa State University, Ames, IA 50011, USA
J Clin Densitom 10:395-403. 2007..Further investigation is needed to examine the relationship of Hcy as an endogenous bioactive molecule to trabecular bone loss in early postmenopausal women and the response of trabecular bone to dietary intervention... - Association of oxidative stress, iron, and centralized fat mass in healthy postmenopausal womenBetsy L Crist
Department of Food Science and Human Nutrition, Iowa State University, Ames, Iowa 50011, USA
J Womens Health (Larchmt) 18:795-801. 2009..The objective of this study was to determine the relationship among excess iron, oxidative stress, and centralized fat mass in healthy postmenopausal women... - Iron indexes and total antioxidant status in response to soy protein intake in perimenopausal womenJames H Swain
Department of Food Science and Human Nutrition, Iowa State University, Ames, 50011, USA
Am J Clin Nutr 76:165-71. 2002..CONCLUSIONS: SPI intake had no significant effect on iron status, but our results suggest that dietary soy protein and low iron stores may protect perimenopausal women from oxidative stress... - Body composition, dietary intake, and iron status of female collegiate swimmers and diversHeidi L Petersen
Iowa State University, Ames 50011, USA
Int J Sport Nutr Exerc Metab 16:281-95. 2006..046) and hematocrit (P = 0.014) and decreases in serum transferrin receptor (P < or = 0.0001). Studies are needed to further evaluate body composition and iron status in relation to dietary intake in female swimmers... - Blood lipid and oxidative stress responses to soy protein with isoflavones and phytic acid in postmenopausal womenHeather M Engelman
Department of Food Science and Human Nutrition, Center for Designing Foods to Improve Nutrition, Iowa State University, Ames, IA 50011, USA
Am J Clin Nutr 81:590-6. 2005..CONCLUSION: In postmenopausal women, neither phytate nor isoflavones in SPI have a significant effect of reducing oxidative damage or favorably altering blood lipids... - Centrally located body fat is related to inflammatory markers in healthy postmenopausal womenCourtney D Perry
Department of Food Science and Human Nutrition, Human Metabolic Unit, Center for Designing Foods to Improve Nutrition, Iowa State University, Ames, IA 50011, USA
Menopause 15:619-27. 2008..The purpose of this multicenter study was to identify whether centrally located fat and/or overall adiposity were related to these inflammatory markers in healthy postmenopausal women... - A single daily dose of soybean phytosterols in ground beef decreases serum total cholesterol and LDL cholesterol in young, mildly hypercholesterolemic menOksana A Matvienko
Department of Food Science and Human Nutrition, Human Metabolic Unit, Iowa State University, Ames, USA
Am J Clin Nutr 76:57-64. 2002..CONCLUSION: Phytosterol-supplemented ground beef effectively lowers plasma TC and LDL cholesterol and has the potential to become a functional food to help reduce the risk of cardiovascular disease... - Quantifying leisure physical activity and its relation to bone density and strengthKristine M Shedd
Nutrition Department, University of California, Davis, CA 95616, USA
Med Sci Sports Exerc 39:2189-98. 2007.... - Isoflavones and postmenopausal womenD Lee Alekel
JAMA 292:2336; author reply 2337. 2004 - Skeletal benefits of soy isoflavones: a review of the clinical trial and epidemiologic dataMark Messina
Department of Nutrition, School of Public Health, Loma Linda University, Loma Linda, California, USA
Curr Opin Clin Nutr Metab Care 7:649-58. 2004..The purpose of this review is to evaluate the clinical and epidemiologic studies relevant to the hypothesis that isoflavones promote bone health...
Research Grants
- Bone Response to Soy Isoflavones in WomenD Lee Alekel; Fiscal Year: 2007....