Paul F Predki

Summary

Affiliation: Invitrogen Corporation
Country: USA

Publications

  1. ncbi request reprint Functional protein microarrays: ripe for discovery
    Paul F Predki
    Protometrix Inc, 688 E Main St, Branford, CT 06405, USA
    Curr Opin Chem Biol 8:8-13. 2004
  2. ncbi request reprint Protein microarrays: a new tool for profiling antibody cross-reactivity
    Paul F Predki
    Invitrogen Protein Microarray Center, 688 E Main St, Branford, CT 06405, USA
    Hum Antibodies 14:7-15. 2005
  3. ncbi request reprint Protein microarray-based screening of antibody specificity
    Rhonda Bangham
    Research and Development, Protometrix Inc, Branford, CT, USA
    Methods Mol Med 114:173-82. 2005
  4. ncbi request reprint Identification of small molecule targets on functional protein microarrays
    Michael Salcius
    Invitrogen Corporation, Branford, CT, USA
    Methods Mol Biol 382:239-48. 2007
  5. ncbi request reprint Functional protein microarrays: just how functional are they?
    Janie S Merkel
    Invitrogen Corporation, Protein Microarray Center, 688 East Main Street, Branford, Connecticut 06405, USA
    Curr Opin Biotechnol 16:447-52. 2005
  6. ncbi request reprint Development of functional protein microarrays for drug discovery: progress and challenges
    Fang X Zhou
    Protometrix Division of Invitrogen Life Technologies, 688 E Main St, Branford, CT 06405, USA
    Comb Chem High Throughput Screen 7:539-46. 2004
  7. ncbi request reprint Analyzing antibody specificity with whole proteome microarrays
    Gregory A Michaud
    Protometrix, 688 East Main Street, Branford, Connecticut 06405, USA
    Nat Biotechnol 21:1509-12. 2003
  8. pmc A pooling-deconvolution strategy for biological network elucidation
    Fulai Jin
    Department of Molecular and Medical Pharmacology, David Geffen School of Medicine, and the Molecular Biology Institute, University of California, Los Angeles, California 90095, USA
    Nat Methods 3:183-9. 2006
  9. ncbi request reprint A critical role for cortactin phosphorylation by Abl-family kinases in PDGF-induced dorsal-wave formation
    Scott N Boyle
    Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT 06520, USA
    Curr Biol 17:445-51. 2007
  10. ncbi request reprint Global analysis of protein phosphorylation in yeast
    Jason Ptacek
    Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, Connecticut 06511, USA
    Nature 438:679-84. 2005

Research Grants

  1. Human Protein Kinase Microarrays
    Paul Predki; Fiscal Year: 2004

Collaborators

  • Lihao Meng
  • Barry Schweitzer
  • Michael Snyder
  • Dawn R Mattoon
  • Gregory A Michaud
  • Fang Zhou
  • Michael Salcius
  • Scott N Boyle
  • Fulai Jin
  • Janie S Merkel
  • Rhonda Bangham
  • Jason Ptacek
  • Anthony J Koleske
  • Jing Huang
  • Tony Hazbun
  • Stanley Fields
  • Brenda Andrews
  • Mike Tyers
  • David F Stern
  • Joseph Fasolo
  • Geeta Devgan
  • Angie S Mah
  • Mark Gerstein
  • Xiaowei Zhu
  • Claudio De Virgilio
  • Martin C Schmidt
  • Heng Zhu
  • Ghil Jona
  • Michael J R Stark
  • Najma Rachidi
  • Rhonda R McCartney
  • Richelle Sopko
  • Soo Jung Lee
  • Hong Guo
  • Ashton Breitkreutz

Detail Information

Publications10

  1. ncbi request reprint Functional protein microarrays: ripe for discovery
    Paul F Predki
    Protometrix Inc, 688 E Main St, Branford, CT 06405, USA
    Curr Opin Chem Biol 8:8-13. 2004
    ..The best, however, is yet to come...
  2. ncbi request reprint Protein microarrays: a new tool for profiling antibody cross-reactivity
    Paul F Predki
    Invitrogen Protein Microarray Center, 688 E Main St, Branford, CT 06405, USA
    Hum Antibodies 14:7-15. 2005
    ..This review will focus on reported examples of antibody cross-reactivity, methods used to characterize them, and the recent development and use of protein microarrays for assessing antibody specificity...
  3. ncbi request reprint Protein microarray-based screening of antibody specificity
    Rhonda Bangham
    Research and Development, Protometrix Inc, Branford, CT, USA
    Methods Mol Med 114:173-82. 2005
    ..In this chapter, we present a detailed description of the methods used to probe protein arrays with antibodies as well as the technical issues to consider when carrying out such experiments...
  4. ncbi request reprint Identification of small molecule targets on functional protein microarrays
    Michael Salcius
    Invitrogen Corporation, Branford, CT, USA
    Methods Mol Biol 382:239-48. 2007
    ..In this chapter, we review examples and methods for profiling small molecules on high-content functional protein arrays and discuss considerations for troubleshooting...
  5. ncbi request reprint Functional protein microarrays: just how functional are they?
    Janie S Merkel
    Invitrogen Corporation, Protein Microarray Center, 688 East Main Street, Branford, Connecticut 06405, USA
    Curr Opin Biotechnol 16:447-52. 2005
    ..These reports help to validate the functionality of so-called functional protein microarrays...
  6. ncbi request reprint Development of functional protein microarrays for drug discovery: progress and challenges
    Fang X Zhou
    Protometrix Division of Invitrogen Life Technologies, 688 E Main St, Branford, CT 06405, USA
    Comb Chem High Throughput Screen 7:539-46. 2004
    ..Successful development will empower multiple drug research applications, help fill future HTS pipelines and guide next generation combinatorial chemistry efforts...
  7. ncbi request reprint Analyzing antibody specificity with whole proteome microarrays
    Gregory A Michaud
    Protometrix, 688 East Main Street, Branford, Connecticut 06405, USA
    Nat Biotechnol 21:1509-12. 2003
    ..Our findings show that proteome array technology has potential to improve antibody design and selection for applications in both medicine and research...
  8. pmc A pooling-deconvolution strategy for biological network elucidation
    Fulai Jin
    Department of Molecular and Medical Pharmacology, David Geffen School of Medicine, and the Molecular Biology Institute, University of California, Los Angeles, California 90095, USA
    Nat Methods 3:183-9. 2006
    ..PI-deconvolution should be applicable to a wide range of library-against-library approaches and can also be used to optimize array designs...
  9. ncbi request reprint A critical role for cortactin phosphorylation by Abl-family kinases in PDGF-induced dorsal-wave formation
    Scott N Boyle
    Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT 06520, USA
    Curr Biol 17:445-51. 2007
    ..Our results reveal that Abl-family kinases target cortactin as an effector of cytoskeletal rearrangements in response to PDGF...
  10. ncbi request reprint Global analysis of protein phosphorylation in yeast
    Jason Ptacek
    Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, Connecticut 06511, USA
    Nature 438:679-84. 2005
    ..Because many yeast proteins and pathways are conserved, these results will provide insights into the mechanisms and roles of protein phosphorylation in many eukaryotes...

Research Grants1

  1. Human Protein Kinase Microarrays
    Paul Predki; Fiscal Year: 2004
    ..Comprehensive kinase inhibition profiling will significantly enhance the effectiveness and efficiency of kinase drug development. ..