Research Topics
| Xiquan LiangSummaryAffiliation: Invitrogen Corporation Country: USA Publications
| Collaborators
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Detail Information
Publications
Quantification of change in phosphorylation of BCR-ABL kinase and its substrates in response to Imatinib treatment in human chronic myelogenous leukemia cellsXiquan Liang
Proteomics, R and D Department, Invitrogen Life Science, Carlsbad, CA 92008, USA
Proteomics 6:4554-64. 2006..These results demonstrate the simplicity and utility of SILAC as a method to quantify dynamic changes in phosphorylation at specific sites in response to stimuli or drug treatment in cell culture...
Quantitative comparison of IMAC and TiO2 surfaces used in the study of regulated, dynamic protein phosphorylationXiquan Liang
Invitrogen Corporation, Carlsbad, California, USA
J Am Soc Mass Spectrom 18:1932-44. 2007....
Identification and quantification of proteins differentially secreted by a pair of normal and malignant breast-cancer cell linesXiquan Liang
Invitrogen Corporation, Carlsbad, CA 92008, USA
Proteomics 9:182-93. 2009..These results corroborate models of invasive tumors sustained by elaborate coordination of stromal cells via chemokines and growth factors, while protease inhibitors remodel the ECM to stimulate angiogenesis...
Quantification of membrane and membrane-bound proteins in normal and malignant breast cancer cells isolated from the same patient with primary breast carcinomaXiquan Liang
Life Sciences R and D, Protein Analysis, Invitrogen, Carlsbad, California 92008, USA
J Proteome Res 5:2632-41. 2006..These results indicate that SILAC is a powerful technique that can be extended to the discovery of membrane-bound antigens that may be used to phenotype diseased cells...
Phosphatidylinositol 3-kinase and Src family kinases are required for phosphorylation and membrane recruitment of Dok-1 in c-Kit signalingXiquan Liang
Cell Biology Program and the Molecular Pharmacology and Therapeutics Program, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA
J Biol Chem 277:13732-8. 2002..Taken together, these data indicate that activation of PI 3-kinase by KL promotes binding of the Dok pleckstrin homology domain and Dok-1 recruitment to the plasma membrane where Dok-1 is phosphorylated by Src and/or Tec family kinases...
Glucocorticoids alter the lipid and protein composition of membrane rafts of a murine T cell hybridomaFrancois Van Laethem
Laboratoire de Physiologie Animale, Institut de Biologie et de Médecine Moléculaires, Universite Libre de Bruxelles, Gosselies, Belgium
J Immunol 170:2932-9. 2003....
