Xiquan Liang

Summary

Affiliation: Invitrogen Corporation
Country: USA

Publications

  1. ncbi request reprint Quantification of change in phosphorylation of BCR-ABL kinase and its substrates in response to Imatinib treatment in human chronic myelogenous leukemia cells
    Xiquan Liang
    Proteomics, R and D Department, Invitrogen Life Science, Carlsbad, CA 92008, USA
    Proteomics 6:4554-64. 2006
  2. ncbi request reprint Quantitative comparison of IMAC and TiO2 surfaces used in the study of regulated, dynamic protein phosphorylation
    Xiquan Liang
    Invitrogen Corporation, Carlsbad, California, USA
    J Am Soc Mass Spectrom 18:1932-44. 2007
  3. doi request reprint Identification and quantification of proteins differentially secreted by a pair of normal and malignant breast-cancer cell lines
    Xiquan Liang
    Invitrogen Corporation, Carlsbad, CA 92008, USA
    Proteomics 9:182-93. 2009
  4. ncbi request reprint Quantification of membrane and membrane-bound proteins in normal and malignant breast cancer cells isolated from the same patient with primary breast carcinoma
    Xiquan Liang
    Life Sciences R and D, Protein Analysis, Invitrogen, Carlsbad, California 92008, USA
    J Proteome Res 5:2632-41. 2006
  5. ncbi request reprint Phosphatidylinositol 3-kinase and Src family kinases are required for phosphorylation and membrane recruitment of Dok-1 in c-Kit signaling
    Xiquan Liang
    Cell Biology Program and the Molecular Pharmacology and Therapeutics Program, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA
    J Biol Chem 277:13732-8. 2002
  6. ncbi request reprint Glucocorticoids alter the lipid and protein composition of membrane rafts of a murine T cell hybridoma
    Francois Van Laethem
    Laboratoire de Physiologie Animale, Institut de Biologie et de Médecine Moléculaires, Universite Libre de Bruxelles, Gosselies, Belgium
    J Immunol 170:2932-9. 2003

Collaborators

  • Jarkko Huuskonen
  • MARILYN RESH
  • Francois Van Laethem
  • Fabienne Andris
  • Jean Marie Ruysschaert
  • Thomas M Stulnig
  • Jacques Urbain
  • Oberdan Leo
  • Michel Vandenbranden

Detail Information

Publications6

  1. ncbi request reprint Quantification of change in phosphorylation of BCR-ABL kinase and its substrates in response to Imatinib treatment in human chronic myelogenous leukemia cells
    Xiquan Liang
    Proteomics, R and D Department, Invitrogen Life Science, Carlsbad, CA 92008, USA
    Proteomics 6:4554-64. 2006
    ..These results demonstrate the simplicity and utility of SILAC as a method to quantify dynamic changes in phosphorylation at specific sites in response to stimuli or drug treatment in cell culture...
  2. ncbi request reprint Quantitative comparison of IMAC and TiO2 surfaces used in the study of regulated, dynamic protein phosphorylation
    Xiquan Liang
    Invitrogen Corporation, Carlsbad, California, USA
    J Am Soc Mass Spectrom 18:1932-44. 2007
    ....
  3. doi request reprint Identification and quantification of proteins differentially secreted by a pair of normal and malignant breast-cancer cell lines
    Xiquan Liang
    Invitrogen Corporation, Carlsbad, CA 92008, USA
    Proteomics 9:182-93. 2009
    ..These results corroborate models of invasive tumors sustained by elaborate coordination of stromal cells via chemokines and growth factors, while protease inhibitors remodel the ECM to stimulate angiogenesis...
  4. ncbi request reprint Quantification of membrane and membrane-bound proteins in normal and malignant breast cancer cells isolated from the same patient with primary breast carcinoma
    Xiquan Liang
    Life Sciences R and D, Protein Analysis, Invitrogen, Carlsbad, California 92008, USA
    J Proteome Res 5:2632-41. 2006
    ..These results indicate that SILAC is a powerful technique that can be extended to the discovery of membrane-bound antigens that may be used to phenotype diseased cells...
  5. ncbi request reprint Phosphatidylinositol 3-kinase and Src family kinases are required for phosphorylation and membrane recruitment of Dok-1 in c-Kit signaling
    Xiquan Liang
    Cell Biology Program and the Molecular Pharmacology and Therapeutics Program, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA
    J Biol Chem 277:13732-8. 2002
    ..Taken together, these data indicate that activation of PI 3-kinase by KL promotes binding of the Dok pleckstrin homology domain and Dok-1 recruitment to the plasma membrane where Dok-1 is phosphorylated by Src and/or Tec family kinases...
  6. ncbi request reprint Glucocorticoids alter the lipid and protein composition of membrane rafts of a murine T cell hybridoma
    Francois Van Laethem
    Laboratoire de Physiologie Animale, Institut de Biologie et de Médecine Moléculaires, Universite Libre de Bruxelles, Gosselies, Belgium
    J Immunol 170:2932-9. 2003
    ....