I A Lea

Summary

Affiliation: Integrated Laboratory Systems
Country: USA

Publications

  1. ncbi Genetic pathways and mutation profiles of human cancers: site- and exposure-specific patterns
    I A Lea
    Integrated Laboratory Systems, Inc, Research Triangle Park, NC 27709, USA
    Carcinogenesis 28:1851-8. 2007
  2. ncbi Genetic pathways to colorectal cancer
    Isabel A Lea
    Integrated Laboratory Systems Inc, Research Triangle Park, NC 27709, USA
    Mutat Res 670:96-8. 2009

Detail Information

Publications2

  1. ncbi Genetic pathways and mutation profiles of human cancers: site- and exposure-specific patterns
    I A Lea
    Integrated Laboratory Systems, Inc, Research Triangle Park, NC 27709, USA
    Carcinogenesis 28:1851-8. 2007
    ..05). Furthermore, the TP53 mutational hot spots for lung and laryngeal cancers from smokers included codons 157, 245 and 273, whereas for oral tumors included codons 280 and 281...
  2. ncbi Genetic pathways to colorectal cancer
    Isabel A Lea
    Integrated Laboratory Systems Inc, Research Triangle Park, NC 27709, USA
    Mutat Res 670:96-8. 2009
    ..It is proposed that the higher incidence of mutation at codon 248 is a later event in colorectal tumorigenesis that occurs as the tumors become malignant...