Ruedi H Aebersold

Summary

Affiliation: Institute for Systems Biology
Country: USA

Publications

  1. pmc Identification of androgen-coregulated protein networks from the microsomes of human prostate cancer cells
    Michael E Wright
    Institute for Systems Biology, Seattle, WA 98103, USA
    Genome Biol 5:R4. 2003
  2. pmc A mouse plasma peptide atlas as a resource for disease proteomics
    Qing Zhang
    Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA
    Genome Biol 9:R93. 2008
  3. ncbi request reprint Mass spectrometry-based proteomics
    Ruedi Aebersold
    Institute for Systems Biology, 1441 North 34th Street, Seattle, Washington 98103 8904, USA
    Nature 422:198-207. 2003
  4. ncbi request reprint Quantitative proteome analysis: methods and applications
    Ruedi Aebersold
    Institute for Systems Biology, Seattle, Washington 98103, USA
    J Infect Dis 187:S315-20. 2003
  5. ncbi request reprint A mass spectrometric journey into protein and proteome research
    Ruedi Aebersold
    Institute for Systems Biology, Seattle, Washington 98103, USA
    J Am Soc Mass Spectrom 14:685-95. 2003
  6. ncbi request reprint The need for national centers for proteomics
    Ruedi Aebersold
    Institute for Systems Biology, 1441 North 34th Street, Seattle, WA 98103, USA
    Nat Biotechnol 20:651. 2002
  7. ncbi request reprint Quantitative proteomics of cerebrospinal fluid from patients with Alzheimer disease
    Jing Zhang
    Department of Pathology, University of Washington School of Medicine, Seattle, WA 98104, USA
    J Alzheimers Dis 7:125-33; discussion 173-80. 2005
  8. ncbi request reprint Quantitative proteomic analysis of age-related changes in human cerebrospinal fluid
    Jing Zhang
    Division of Neuropathology, University of Washington School of Medicine, Box 359635, Harborview Medical Center, Seattle, WA 98104, USA
    Neurobiol Aging 26:207-27. 2005
  9. ncbi request reprint Analysis of alpha-synuclein-associated proteins by quantitative proteomics
    Yong Zhou
    Department of Pathology and Medicinal Chemistry, University of Washington School of Medicine, Seattle, Washington 98104, USA
    J Biol Chem 279:39155-64. 2004
  10. ncbi request reprint Proteomics: the first decade and beyond
    Scott D Patterson
    Celera Genomics Corporation, 45 West Gude Drive, Rockville, Maryland 20850, USA
    Nat Genet 33:311-23. 2003

Research Grants

Collaborators

Detail Information

Publications10

  1. pmc Identification of androgen-coregulated protein networks from the microsomes of human prostate cancer cells
    Michael E Wright
    Institute for Systems Biology, Seattle, WA 98103, USA
    Genome Biol 5:R4. 2003
    ..To this end, we have applied a large-scale proteomic approach to define cellular processes that are responsive to androgen treatment in LNCaP prostate cancer cells...
  2. pmc A mouse plasma peptide atlas as a resource for disease proteomics
    Qing Zhang
    Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA
    Genome Biol 9:R93. 2008
    ..A major finding from this study is the identification of novel isoforms and transcript variants not previously predicted from genome analysis...
  3. ncbi request reprint Mass spectrometry-based proteomics
    Ruedi Aebersold
    Institute for Systems Biology, 1441 North 34th Street, Seattle, Washington 98103 8904, USA
    Nature 422:198-207. 2003
    ..The ability of mass spectrometry to identify and, increasingly, to precisely quantify thousands of proteins from complex samples can be expected to impact broadly on biology and medicine...
  4. ncbi request reprint Quantitative proteome analysis: methods and applications
    Ruedi Aebersold
    Institute for Systems Biology, Seattle, Washington 98103, USA
    J Infect Dis 187:S315-20. 2003
    ..The rationale for quantitative proteome analysis is described, along with a new technology for high throughput quantitative profiling of proteins in complex mixtures and its current status with selected applications...
  5. ncbi request reprint A mass spectrometric journey into protein and proteome research
    Ruedi Aebersold
    Institute for Systems Biology, Seattle, Washington 98103, USA
    J Am Soc Mass Spectrom 14:685-95. 2003
    ..Some conclusions from this case study relating to technological research and the environment in which it is carried out are also discussed...
  6. ncbi request reprint The need for national centers for proteomics
    Ruedi Aebersold
    Institute for Systems Biology, 1441 North 34th Street, Seattle, WA 98103, USA
    Nat Biotechnol 20:651. 2002
  7. ncbi request reprint Quantitative proteomics of cerebrospinal fluid from patients with Alzheimer disease
    Jing Zhang
    Department of Pathology, University of Washington School of Medicine, Seattle, WA 98104, USA
    J Alzheimers Dis 7:125-33; discussion 173-80. 2005
    ....
  8. ncbi request reprint Quantitative proteomic analysis of age-related changes in human cerebrospinal fluid
    Jing Zhang
    Division of Neuropathology, University of Washington School of Medicine, Box 359635, Harborview Medical Center, Seattle, WA 98104, USA
    Neurobiol Aging 26:207-27. 2005
    ..These data not only expand substantially our current knowledge regarding human CSF proteins, but also supply the necessary information to appropriately interpret protein biomarkers of age-related neurodegenerative diseases...
  9. ncbi request reprint Analysis of alpha-synuclein-associated proteins by quantitative proteomics
    Yong Zhou
    Department of Pathology and Medicinal Chemistry, University of Washington School of Medicine, Seattle, Washington 98104, USA
    J Biol Chem 279:39155-64. 2004
    ..Furthermore, the protection afforded by hsp70 transfection appeared to be related to suppression of rotenone-induced oxidative stress as well as mitochondrial and proteasomal dysfunction...
  10. ncbi request reprint Proteomics: the first decade and beyond
    Scott D Patterson
    Celera Genomics Corporation, 45 West Gude Drive, Rockville, Maryland 20850, USA
    Nat Genet 33:311-23. 2003
    ....

Research Grants5

  1. CONTROL OF CELL FATE--ROLE OF PROTEIN PHOSPHORYLATION
    Ruedi Aebersold; Fiscal Year: 2000
    ....
  2. CONTROL OF CELL FATE--ROLE OF PROTEIN PHOSPHORYLATION
    Ruedi Aebersold; Fiscal Year: 2001
    ....
  3. ISOTOPE CODED AFFINITY TAGS FOR QUANTITATIVE PROTEOMICS
    Ruedi Aebersold; Fiscal Year: 2002
    ..The technology will thus significantly contribute to the molecular diagnosis, the assessment of the cancer risk and prognosis, and the understanding of the molecular basis of cancer. ..
  4. Proteomics: Technologies and Applications
    Ruedi Aebersold; Fiscal Year: 2003
    ..The goal of the meeting is to bring together the leading experts from the different areas of proteomics research to discuss emerging technologies and their applications to biological and clinical research. ..
  5. Novel Quantitative, Comprehensive Proteomic Technology
    Ruedi Aebersold; Fiscal Year: 2003
    ..We anticipate the proposed pro ram will contribute significant towards fulfilling expectations for cancer research raised by the genomics revolution. ..