John D Seeger

Summary

Affiliation: Ingenix Epidemiology
Country: USA

Publications

  1. ncbi request reprint Achilles tendon rupture and its association with fluoroquinolone antibiotics and other potential risk factors in a managed care population
    John D Seeger
    i3 Drug Safety, Auburndale, MA, USA
    Pharmacoepidemiol Drug Saf 15:784-92. 2006
  2. ncbi request reprint Risk of thromboembolism in women taking ethinylestradiol/drospirenone and other oral contraceptives
    John D Seeger
    i3 Drug Safety, Ingenix, Waltham, Massachusetts 02451, USA
    Obstet Gynecol 110:587-93. 2007
  3. ncbi request reprint An application of propensity score matching using claims data
    John D Seeger
    Ingenix Epidemiology, Auburndale, Massachusetts 02466, USA
    Pharmacoepidemiol Drug Saf 14:465-76. 2005
  4. ncbi request reprint Pregnancy and pregnancy outcome among women with inflammatory skin diseases
    John D Seeger
    Ingenix Epidemiology, Auburndale, MA, USA
    Dermatology 214:32-9. 2007
  5. ncbi request reprint A propensity score-matched cohort study of the effect of statins, mainly fluvastatin, on the occurrence of acute myocardial infarction
    John D Seeger
    Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts, USA
    Am J Cardiol 92:1447-51. 2003
  6. doi request reprint Risk of hyperkalemia in women taking ethinylestradiol/drospirenone and other oral contraceptives
    Jeanne Loughlin
    Ingenix i3 Drug Safety, Waltham, MA 02451, USA
    Contraception 78:377-83. 2008
  7. doi request reprint Supplementary data collection with case-cohort analysis to address potential confounding in a cohort study of thromboembolism in oral contraceptive initiators matched on claims-based propensity scores
    P Mona Eng
    Ingenix, i3 Drug Safety, Waltham, MA 02451, USA
    Pharmacoepidemiol Drug Saf 17:297-305. 2008
  8. doi request reprint Effectiveness of an incomplete RotaTeq (RV5) vaccination regimen in preventing rotavirus gastroenteritis in the United States
    Florence T Wang
    OptumInsight Epidemiology, Waltham, MA 02451, USA
    Pediatr Infect Dis J 32:278-83. 2013
  9. pmc Long-term effects of highly active antiretroviral therapy on CD4+ cell evolution among children and adolescents infected with HIV: 5 years and counting
    Kunjal Patel
    Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts 02115, USA
    Clin Infect Dis 46:1751-60. 2008
  10. doi request reprint Postmarketing evaluation of the short-term safety of the pentavalent rotavirus vaccine
    Jeanne Loughlin
    Epidemiology, OptumInsight, Waltham, MA 02451, USA
    Pediatr Infect Dis J 31:292-6. 2012

Detail Information

Publications46

  1. ncbi request reprint Achilles tendon rupture and its association with fluoroquinolone antibiotics and other potential risk factors in a managed care population
    John D Seeger
    i3 Drug Safety, Auburndale, MA, USA
    Pharmacoepidemiol Drug Saf 15:784-92. 2006
    ..We sought to quantify the strength of association between exposure to fluoroquinolone antibiotics and the occurrence of ATR, accounting for other risk factors...
  2. ncbi request reprint Risk of thromboembolism in women taking ethinylestradiol/drospirenone and other oral contraceptives
    John D Seeger
    i3 Drug Safety, Ingenix, Waltham, Massachusetts 02451, USA
    Obstet Gynecol 110:587-93. 2007
    ..We sought to estimate the association between ethinylestradiol/drospirenone and risk of thromboembolism relative to the association among other oral contraceptives...
  3. ncbi request reprint An application of propensity score matching using claims data
    John D Seeger
    Ingenix Epidemiology, Auburndale, Massachusetts 02466, USA
    Pharmacoepidemiol Drug Saf 14:465-76. 2005
    ..In such settings, there will typically be many more variables available for control as potential confounders than traditional epidemiologic techniques will allow...
  4. ncbi request reprint Pregnancy and pregnancy outcome among women with inflammatory skin diseases
    John D Seeger
    Ingenix Epidemiology, Auburndale, MA, USA
    Dermatology 214:32-9. 2007
    ..The effect of inflammatory skin diseases on pregnancy has been incompletely characterized. We sought to estimate the incidence of pregnancy and pregnancy outcomes among women with inflammatory skin diseases...
  5. ncbi request reprint A propensity score-matched cohort study of the effect of statins, mainly fluvastatin, on the occurrence of acute myocardial infarction
    John D Seeger
    Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts, USA
    Am J Cardiol 92:1447-51. 2003
    ..Serum low-density lipoprotein levels were reduced by statin therapy, and there were fewer incidents of AMI in statin initiators than in noninitiators...
  6. doi request reprint Risk of hyperkalemia in women taking ethinylestradiol/drospirenone and other oral contraceptives
    Jeanne Loughlin
    Ingenix i3 Drug Safety, Waltham, MA 02451, USA
    Contraception 78:377-83. 2008
    ..We sought to determine whether EE/DRSP use might lead to adverse effects possibly attributable to hyperkalemia...
  7. doi request reprint Supplementary data collection with case-cohort analysis to address potential confounding in a cohort study of thromboembolism in oral contraceptive initiators matched on claims-based propensity scores
    P Mona Eng
    Ingenix, i3 Drug Safety, Waltham, MA 02451, USA
    Pharmacoepidemiol Drug Saf 17:297-305. 2008
    ..g., smoking and obesity) not captured in claims data in a claims-based cohort study of thromboembolism among matched oral contraceptive (OC) initiators...
  8. doi request reprint Effectiveness of an incomplete RotaTeq (RV5) vaccination regimen in preventing rotavirus gastroenteritis in the United States
    Florence T Wang
    OptumInsight Epidemiology, Waltham, MA 02451, USA
    Pediatr Infect Dis J 32:278-83. 2013
    ..This study assessed the effectiveness of RV5 following partial completion of the 3-dose regimen...
  9. pmc Long-term effects of highly active antiretroviral therapy on CD4+ cell evolution among children and adolescents infected with HIV: 5 years and counting
    Kunjal Patel
    Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts 02115, USA
    Clin Infect Dis 46:1751-60. 2008
    ....
  10. doi request reprint Postmarketing evaluation of the short-term safety of the pentavalent rotavirus vaccine
    Jeanne Loughlin
    Epidemiology, OptumInsight, Waltham, MA 02451, USA
    Pediatr Infect Dis J 31:292-6. 2012
    ..Secondary objectives assessed the occurrence of Kawasaki disease (KD) and general safety...
  11. doi request reprint A matched cohort study of the risk of cancer in users of becaplermin
    Najat Ziyadeh
    Ingenix, i3 Drug Safety, Waltham, Massachusetts, USA
    Adv Skin Wound Care 24:31-9. 2011
    ..8 (95% confidence interval [CI], 0.6-12.8). The authors aimed to further investigate any association between becaplermin use and the occurrence of cancer by following a large cohort of patients in a clinical practice setting...
  12. doi request reprint Extended case-control study results on thromboembolic outcomes among transdermal contraceptive users
    David D Dore
    i3 Drug Safety, Waltham, MA 02451, USA
    Contraception 81:408-13. 2010
    ..We extended an earlier study that found a twofold higher risk of venous thromboembolism (VTE) associated with the transdermal contraceptive system relative to norgestimate-containing oral contraceptives (NGM-OC)...
  13. doi request reprint Adherence to recommended dosing and monitoring for mitoxantrone in patients with multiple sclerosis: a healthcare claims database study supplemented with medical records--the RETRO study
    Donnie Funch
    Epidemiology, i3 Drug Safety, Waltham, MA 02451, USA
    Pharmacoepidemiol Drug Saf 19:448-56. 2010
    ..We sought to estimate provider adherence to dosing and monitoring guidelines and the effect of changes in LVEF monitoring guidelines...
  14. pmc The Zelnorm epidemiologic study (ZEST): a cohort study evaluating incidence of abdominal and pelvic surgery related to tegaserod treatment
    John D Seeger
    Brigham and Women s Hospital and Harvard Medical School, Boston, MA, USA
    BMC Gastroenterol 12:171. 2012
    ..We sought to quantify the association between tegaserod use and the occurrence of abdominal or pelvic surgery, including cholecystectomy...
  15. doi request reprint Incidence of intussusception among infants in a large commercially insured population in the United States
    Patricia Mona Eng
    Epidemiology, OptumInsight, Waltham, MA 02451, USA
    Pediatr Infect Dis J 31:287-91. 2012
    ..To estimate the incidence of intussusception among infants treated in inpatient and emergency department settings during the period preceding the US launch of second-generation rotavirus vaccines...
  16. doi request reprint Tegaserod and the risk of cardiovascular ischemic events: an observational cohort study
    Jeanne Loughlin
    Ingenix, i3 Drug Safety, Waltham, MA, USA
    J Cardiovasc Pharmacol Ther 15:151-7. 2010
    ..We sought to evaluate whether there was an association between tegaserod and CVIE in a setting of routine clinical practice...
  17. ncbi request reprint Lipid profiles among US elderly with untreated rheumatoid arthritis--the Third National Health and Nutrition Examination Survey
    Hyon K Choi
    Rheumatology Unit, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114, USA
    J Rheumatol 32:2311-6. 2005
    ..Recent studies suggest that patients with active rheumatoid arthritis (RA) have adverse serum lipid profiles. We examined lipid profiles among individuals with RA in a national sample of persons aged 60 years and older...
  18. ncbi request reprint Use of propensity score technique to account for exposure-related covariates: an example and lesson
    John D Seeger
    Ingenix i3 Drug Safety, Waltham, Massachusetts, USA
    Med Care 45:S143-8. 2007
    ..Although propensity scores are used increasingly often, their limitations in settings without complete data may not be recognized...
  19. ncbi request reprint Patterns and trends in insulin intensification among patients with type 2 diabetes: A systematic review
    Jennifer M Polinski
    Division of Pharmacoepidemiology and Pharmacoeconomics, Brigham and Women s Hospital, Boston, MA, United States Harvard Medical School, Boston, MA, United States Electronic address
    Prim Care Diabetes 8:101-9. 2014
    ..The paucity of available studies prevented a comprehensive understanding of patterns and trends in insulin intensification. Such information is needed to assess the quality of pharmacologic care for patients with T2DM. ..
  20. doi request reprint Stratum-specific positive predictive values of claims for acute pancreatitis among commercial health insurance plan enrollees with diabetes mellitus
    David D Dore
    i3 Drug Safety, Waltham, MA 02451, USA
    Pharmacoepidemiol Drug Saf 20:209-13. 2011
    ..To estimate the positive predictive value (PPV) of claims for acute pancreatitis among initiators of antihyperglycemic drugs in commercial health insurance claims data...
  21. ncbi request reprint Serum potassium monitoring for users of ethinyl estradiol/drospirenone taking medications predisposing to hyperkalemia: physician compliance and survey of knowledge and attitudes
    Patricia Mona Eng
    i3 Drug Safety, Riverside Center 3 120, 275 Grove Street, Auburndale, MA 02466, USA
    Contraception 75:101-7. 2007
    ..Product labeling recommends potassium monitoring in the first month of use for women concurrently receiving medication that may increase serum potassium...
  22. ncbi request reprint Incidence of allergic reactions associated with antibacterial use in a large, managed care organisation
    Catherine B Johannes
    i3 Drug Safety, Waltham, MA 02451, USA
    Drug Saf 30:705-13. 2007
    ..Data on the incidence of serious allergic reactions to fluoroquinolone antibacterials are mainly derived from spontaneous reports that cannot be used to accurately estimate incidence...
  23. ncbi request reprint The risk of coronary heart disease in type 2 diabetic patients exposed to thiazolidinediones compared to metformin and sulfonylurea therapy
    Catherine B Johannes
    i3 Drug Safety, Auburndale, MA, USA
    Pharmacoepidemiol Drug Saf 16:504-12. 2007
    ..To evaluate whether the risk of coronary heart disease (CHD) differs among adult diabetic patients treated with thiazolidinediones (TZDs) and similar patients treated with combined oral metformin and sulfonylurea (M + S) therapy...
  24. ncbi request reprint Patterns of opioid utilization in pregnancy in a large cohort of commercial insurance beneficiaries in the United States
    Brian T Bateman
    From the Department of Anesthesia, Critical Care, and Pain Medicine, Massachusetts General Hospital, and Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts B T B Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts S H D Department of Anesthesia, Critical Care, and Pain Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts J P R and Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts J D S, M D, M A F, K F H
    Anesthesiology 120:1216-24. 2014
    ..There are few data regarding the utilization of opioids during pregnancy. The objective of this study was to define the prevalence and patterns of opioid use in a large cohort of pregnant women who were commercial insurance beneficiaries...
  25. ncbi request reprint Trends in insulin initiation and treatment intensification among patients with type 2 diabetes
    Amanda R Patrick
    Division of Pharmacoepidemiology and Pharmacoeconomics, Brigham and Women s Hospital, 1620 Tremont Street, Suite 3030, Boston, MA, 02120, USA
    J Gen Intern Med 29:320-7. 2014
    ....
  26. pmc Estimation using all available covariate information versus a fixed look-back window for dichotomous covariates
    Steven M Brunelli
    Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02120, USA
    Pharmacoepidemiol Drug Saf 22:542-50. 2013
    ..When available historical data differs among subjects, investigators must choose between using all available historical data versus data from a fixed window to assess C. Our purpose was to compare estimation under these two approaches...
  27. doi request reprint Aprotinin during coronary-artery bypass grafting and risk of death
    Sebastian Schneeweiss
    Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02120, USA
    N Engl J Med 358:771-83. 2008
    ..Aprotinin (Trasylol) is used to mitigate bleeding during coronary-artery bypass grafting (CABG). Accumulating evidence suggests that this practice increases mortality...
  28. ncbi request reprint Use of a claims-based active drug safety surveillance system to assess the risk of acute pancreatitis with exenatide or sitagliptin compared to metformin or glyburide
    David D Dore
    i3 Drug Safety, 950 Winter Street, Waltham, MA 02451, USA
    Curr Med Res Opin 25:1019-27. 2009
    ....
  29. doi request reprint The effectiveness of varenicline medication guide for conveying safety information to patients: a REMS assessment survey
    Cheryl Enger
    OptumInsight Epidemiology, Waltham, MA 48108, USA
    Pharmacoepidemiol Drug Saf 22:705-15. 2013
    ..To evaluate the effectiveness of the varenicline MG as a REMS tool for educating patients, we undertook a survey among patients who were dispensed varenicline...
  30. doi request reprint Long-term effectiveness of highly active antiretroviral therapy on the survival of children and adolescents with HIV infection: a 10-year follow-up study
    Kunjal Patel
    Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts 02115, USA
    Clin Infect Dis 46:507-15. 2008
    ..Given that HIV infection is chronic and that exposure to HAART is likely to be life-long, there is a need to evaluate the long-term effect of HAART on survival in this population...
  31. doi request reprint Linkage of routinely collected oncology clinical data with health insurance claims data--an example with aromatase inhibitors, tamoxifen, and all-cause mortality
    David D Dore
    Departments of Health Services, Policy and Practice and Epidemiology, Program in Public Health, The Warren Alpert Medical School of Brown University, Providence, RI, USA
    Pharmacoepidemiol Drug Saf 21:29-36. 2012
    ..Our objective was to evaluate routinely collected cancer clinical data for adjustment of confounding using an example evaluation of mortality associated with aromatase inhibitors and tamoxifen...
  32. doi request reprint Effectiveness of the pentavalent rotavirus vaccine in preventing gastroenteritis in the United States
    Florence T Wang
    Drug Safety, Department of Epidemiology, 950 Winter St, Suite 3800, Waltham, MA 02451, USA
    Pediatrics 125:e208-13. 2010
    ..We assessed the vaccine effectiveness (VE) of RV5 among US infants during the first 2 rotavirus seasons after vaccine licensure...
  33. ncbi request reprint Effects of rofecoxib and naproxen on life expectancy among patients with rheumatoid arthritis: a decision analysis
    Hyon K Choi
    Department of Health Policy and Management, Boston, Massachusetts, USA
    Am J Med 116:621-9. 2004
    ..We examined the effects of these competing adverse events on life expectancy in patients with rheumatoid arthritis...
  34. doi request reprint Topical treatments with pimecrolimus, tacrolimus and medium- to high-potency corticosteroids, and risk of lymphoma
    Sebastian Schneeweiss
    Department of Epidemiology, Harvard School of Public Health, Boston, MA, USA
    Dermatology 219:7-21. 2009
    ..A potential risk of lymphoma associated with the use of topical calcineurin inhibitors is debated. We assessed the risk of lymphoma among patients treated with topical pimecrolimus, tacrolimus or corticosteroids...
  35. ncbi request reprint The comparative safety of rosuvastatin: a retrospective matched cohort study in over 48,000 initiators of statin therapy
    Andrew T McAfee
    i3 Drug Safety, Newton, MA 02466, USA
    Pharmacoepidemiol Drug Saf 15:444-53. 2006
    ..The purpose of this study was to compare incidence rates of hospitalization associated with rhabdomyolysis, myopathy, renal, or hepatic dysfunction, and of in-hospital death, between initiators of rosuvastatin and other statins...
  36. doi request reprint Vaccine discontinuation and switching following regulatory interventions in response to rotavirus vaccine contamination with porcine circovirus DNA fragments
    David D Dore
    Departments of Health Services, Policy and Practice and Epidemiology Program in Public Health, The Warren Alpert Medical School of Brown University, Providence, RI, USA
    Pharmacoepidemiol Drug Saf 21:415-9. 2012
    ..We assessed the utilization of these vaccines in relation to the announcements...
  37. doi request reprint Atomoxetine and cerebrovascular outcomes in adults
    Crystal N Holick
    i3 Drug Safety, Waltham, MA, USA
    J Clin Psychopharmacol 29:453-60. 2009
    ..The aim of this study was to estimate the association between atomoxetine and cerebrovascular accident (CVA) and transient ischemic attack (TIA) in adults...
  38. doi request reprint Barriers to insulin progression among patients with type 2 diabetes: a systematic review
    Jennifer M Polinski
    Division of Pharmacoepidemiology and Pharmacoeconomics, Brigham and Women s Hospital, 1620 Tremont Street, Suite 3030, Boston, MA 02120, USA
    Diabetes Educ 39:53-65. 2013
    ..progression among patients with type 2 diabetes: (1) What are the patient, provider, and health system barriers to insulin progression? (2) Do insulin progression barriers differ between insulin-naive and insulin-experienced patients?..
  39. doi request reprint Impact of baseline heart failure burden on post-implantable cardioverter-defibrillator mortality among medicare beneficiaries
    Chih Ying Chen
    Division of Pharmacoepidemiology and Pharmacoeconomics, Brigham and Women s Hospital, Boston, Massachusetts, USA
    J Am Coll Cardiol 61:2142-50. 2013
    ..This study sought to assess the impact of baseline heart failure (HF) burden on survival with primary implantable cardioverter-defibrillator (ICD) among Medicare recipients...
  40. ncbi request reprint Observational research in rheumatic disorders
    Hyon K Choi
    Rheumatology Unit, Department of Medicine, Massachusetts General Hospital, Bulfinch 165, 55 Fruit Street, Boston, MA 02114, USA
    Rheum Dis Clin North Am 30:685-99, v. 2004
    ..This article reviews the scope of observational studies, principles of causal inference in observational studies, and various types of observational studies with a focus of their applications in rheumatic disorders...
  41. ncbi request reprint Glucocorticoid use and serum lipid levels in US adults: the Third National Health and Nutrition Examination Survey
    Hyon K Choi
    Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114, USA
    Arthritis Rheum 53:528-35. 2005
    ..In this study, we sought to examine the relationship between glucocorticoid use and lipid profiles in a nationally representative sample of subjects...
  42. ncbi request reprint Methotrexate and mortality in patients with rheumatoid arthritis: a prospective study
    Hyon K Choi
    Arthritis Unit, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Harvard School of Public Health, Boston, MA, USA
    Lancet 359:1173-7. 2002
    ..Our aim was to prospectively assess the effect on mortality of methotrexate in a cohort of patients with rheumatoid arthritis...
  43. ncbi request reprint A cost effectiveness analysis of treatment options for methotrexate-naive rheumatoid arthritis
    Hyon K Choi
    Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston 02114, USA
    J Rheumatol 29:1156-65. 2002
    ..Given wide variability in efficacy and cost among different treatment options, we sought to determine their relative cost effectiveness to help guide policy in different cost constrained settings...
  44. ncbi request reprint Causal structures for evaluating statin class effects
    John D Seeger
    Ann Pharmacother 36:1961-5. 2002
  45. ncbi request reprint Statin use and fracture risk
    John D Seeger
    Arch Intern Med 162:2379-80; author reply 2380. 2002
  46. ncbi request reprint Statin use and risk of prostate cancer in the California Men's Health Study cohort
    E Dawn Flick
    Division of Research, Kaiser Permanente, 2000 Broadway, 5th Floor, Oakland, CA 94612, USA
    Cancer Epidemiol Biomarkers Prev 16:2218-25. 2007
    ..Our findings suggest that long-term statin use might be associated with a reduced risk of prostate cancer but perhaps only among regular nonsteroidal anti-inflammatory drug users...