Research Topics
| Susan L BaldwinSummaryAffiliation: Infectious Disease Research Institute Country: USA Publications
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Detail Information
Publications
Intradermal immunization improves protective efficacy of a novel TB vaccine candidateSusan L Baldwin
Infectious Disease Research Institute, Seattle, WA 98104, USA
Vaccine 27:3063-71. 2009..This highlights the need to explore different routes of immunization based on the adjuvant formulations used...
Enhanced humoral and Type 1 cellular immune responses with Fluzone adjuvanted with a synthetic TLR4 agonist formulated in an emulsionSusan L Baldwin
Infectious Disease Research Institute, 1124 Columbia Street, Suite 400, Seattle, WA 98104, United States
Vaccine 27:5956-63. 2009....
Increased potency of an inactivated trivalent polio vaccine with oil-in-water emulsionsSusan L Baldwin
Infectious Disease Research Institute, 1124 Columbia St, Suite 400, Seattle, WA 98104, USA
Vaccine 29:644-9. 2011..Our results show that the addition of oil-in-water emulsion adjuvants to an, inactivated trivalent poliovirus vaccine are dose-sparing and are capable of enhancing, neutralizing antibody titers in the rat potency model...
The importance of adjuvant formulation in the development of a tuberculosis vaccineSusan L Baldwin
Infectious Disease Research Institute, Seattle, WA 98104, USA
J Immunol 188:2189-97. 2012..These results highlight the importance of properly formulating subunit vaccines with effective adjuvants for use against tuberculosis...
Identification of human T cell antigens for the development of vaccines against Mycobacterium tuberculosisSylvie Bertholet
Infectious Disease Research Institute, Seattle WA 98104, USA
J Immunol 181:7948-57. 2008..This study identified numerous novel human T cell Ags suitable to be included in subunit vaccines against tuberculosis...
Development and characterization of synthetic glucopyranosyl lipid adjuvant system as a vaccine adjuvantRhea N Coler
Preclinical Biology, Infectious Disease Research Institute, Seattle, Washington, United States of America
PLoS ONE 6:e16333. 2011....
Immunomodulatory and physical effects of phospholipid composition in vaccine adjuvant emulsionsChristopher B Fox
Infectious Disease Research Institute, 1124 Columbia St, Ste 400, Seattle, Washington 98104, USA
AAPS PharmSciTech 13:498-506. 2012....
Therapeutic immunization against Mycobacterium tuberculosis is an effective adjunct to antibiotic treatmentRhea N Coler
Infectious Disease Research Institute, Seattle, Washington, USA
J Infect Dis 207:1242-52. 2013....
Immunomodulatory and physical effects of oil composition in vaccine adjuvant emulsionsChristopher B Fox
Infectious Disease Research Institute, 1124 Columbia St, Ste 400, Seattle, WA 98104, United States
Vaccine 29:9563-72. 2011....
Transcriptional profiling of TLR-4/7/8-stimulated guinea pig splenocytes and whole blood by bDNA assayLance K Ching
Infectious Disease Research Institute, 1124 Columbia Street, Suite 400, Seattle, WA 98104, USA
J Immunol Methods 373:54-62. 2011..Overall, the QuantiGene platform is reliable, reproducible, and sensitive. These agonists have the potential to be used as adjuvant components in vaccines against various pathogens...
A defined tuberculosis vaccine candidate boosts BCG and protects against multidrug-resistant Mycobacterium tuberculosisSylvie Bertholet
Infectious Disease Research Institute, 1124 Columbia Street, Suite 400, Seattle, WA 98104, USA
Sci Transl Med 2:53ra74. 2010....
A synthetic adjuvant to enhance and expand immune responses to influenza vaccinesRhea N Coler
Infectious Disease Research Institute, Seattle, Washington, United States of America
PLoS ONE 5:e13677. 2010..These results suggest that synthetic TLR4 adjuvants can enhance the magnitude and quality of protective immunity induced by influenza vaccines...
Effects on immunogenicity by formulations of emulsion-based adjuvants for malaria vaccinesChristopher B Fox
Infectious Disease Research Institute, Seattle, Washington, USA
Clin Vaccine Immunol 19:1633-40. 2012..Emulsion dose titration in the absence of formulated GLA caused some reduction in humoral and cellular immune responses compared to those with the 2% squalene emulsion dose...
Adjuvant solution for pandemic influenza vaccine productionChristopher H Clegg
TRIA Bioscience Corp, Seattle, WA 98104, USA
Proc Natl Acad Sci U S A 109:17585-90. 2012..Innate signaling pathways that amplify priming of Th1 CD4 T cells will likely improve vaccine performance against future outbreaks of lethal pandemic flu...

