Research Topics
| X H ZhouSummaryAffiliation: Indiana University Country: USA Publications
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Detail Information
Publications
Methods for combining rates from several studiesX H Zhou
Department of Medicine, Indiana University School of Medicine, Indianapolis 46202 5119, USA
Stat Med 18:557-66. 1999..Finally, we illustrate these two methods and obtain bootstrap confidence intervals in a medical example analysing the effectiveness of hyperdynamic therapy for cerebral vasospasm...- Correcting for verification bias in studies of a diagnostic test's accuracyX H Zhou
Department of Medicine, Indiana University School of Medicine, Regenstrief Health Center, Indianapolis 46202 2859, USA
Stat Methods Med Res 7:337-53. 1998..This paper reviews recent developments in bias-correction methods for studies on the accuracy of diagnostic tests... - Assessing the relative accuracies of two screening tests in the presence of verification biasX H Zhou
Division of Biostatistics, Department of Medicine, Indiana University School of Medicine, Regenstrief Institute for Health Care, Indianapolis 46202, USA
Stat Med 19:1697-705. 2000..We illustrate the application of the proposed methods to a simulated data set from a real two-stage study of dementia that has motivated this research... - Confidence intervals for the mean of diagnostic test charge data containing zerosX H Zhou
Division of Biostatistics, Department of Medicine, Indiana University School of Medicine, RG 4th, 1001 West 10th Street, Indianapolis, Indiana 46202 2859, USA
Biometrics 56:1118-25. 2000..When the sample size is large, all three proposed intervals have similar coverage accuracy. Finally, we analyze with the proposed methods one real example assessing diagnostic test charges among older adults with depression... - Multiple imputation in public health researchX H Zhou
Division of Biostatistics, Department of Medicine, Indiana University School of Medicine, Indianapolis 46202, USA
Stat Med 20:1541-9. 2001..The simulation also showed better standard deviation estimates for multiple imputation than for single mean imputation... - Methods for testing equality of means of health care costs in a paired design studyX H Zhou
Division of Biostatistics, Indiana University School of Medicine, 1050 Wishard Boulevard, Indianapolis, IN 46202, U S A
Stat Med 20:1703-20. 2001.... - Inferences about population means of health care costsXiao Hua Zhou
Division of Biostatistics, Department of Medicine, Indiana University School of Medicine, RG 4101, 1050 Wishard Blvd, Indianapolis, IN 46202, USA
Stat Methods Med Res 11:327-39. 2002..Statistical methods that do not adjust for these features can lead to incorrect conclusions. This paper reviews recent developments in statistical methods for the analysis of health care costs; our focus is on population means... 
The effect of discussions about advance directives on patients' satisfaction with primary careW M Tierney
Department of Medicine, Indiana University School of Medicine, Indianapolis
J Gen Intern Med 16:32-40. 2001..Many barriers to having such discussions during primary care exist. These barriers include time constraints, communication difficulties, and perhaps physicians' anxiety that patients might react negatively to such discussions...- Examination of racial differences in management of cardiovascular diseaseJ A Ferguson
Center for Health Services Research, Roudebush Veterans Affairs Medical Center, Department of Medicine, Indiana University School of Medicine, Indianapolis 46202, USA
J Am Coll Cardiol 30:1707-13. 1997..We sought to identify the clinical characteristics associated with, and to investigate the impact of cohort selection criteria on, interracial use of invasive cardiac procedures and to determine survival... - Restricting medicaid payments for transportation: effects on inner-city patients' health careW M Tierney
Regenstrief Institute for Health Care, Wishard Memorial Hospital and The Indiana University School of Medicine, Indianapolis, USA
Am J Med Sci 319:326-33. 2000..We evaluated the effect of a change in Indiana Medicaid's policy (effective October 1, 1993) requiring prior approval to pay transportation costs... - Work patterns of ambulatory care pharmacists with access to electronic guideline-based treatment suggestionsM D Murray
Department of Pharmacy Practice, School of Pharmacy, Purdue University, Indianapolis, IN, USA
Am J Health Syst Pharm 56:225-32. 1999..The delivery of patient-specific information to pharmacists at the time of dispensing had a significant positive impact on pharmacist work patterns... - Preferences of physicians and their patients for end-of-life careG P Gramelspacher
Department of Medicine, Indiana University School of Medicine, Indianapolis, USA
J Gen Intern Med 12:346-51. 1997..Reasons for this correlation are unknown... - Effects of computer-based prescribing on pharmacist work patternsM D Murray
Purdue University, USA
J Am Med Inform Assoc 5:546-53. 1998..To measure the effect of computer-based outpatient prescription writing by internal medicine physicians on pharmacist work patterns... - Estimation of the log-normal meanX H Zhou
Department of Medicine, Indiana University School of Medicine, Indianapolis 46202 5119, USA
Stat Med 17:2251-64. 1998..Since the ML estimator is the easiest to compute among these three estimators, for large samples we recommend the use of the ML estimator. For small to moderate samples, we recommend the use of the conditionally minimal MSE estimator... - Risk of major hemorrhage for outpatients treated with warfarinD A McMahan
Richard L. Roudebush VAMC, Department of Medicine, Indiana University School of Medicine, Indianapolis, USA
J Gen Intern Med 13:311-6. 1998..Alcohol abuse, chronic renal insufficiency, and a previous gastrointestinal bleed were associated with increased risk of major hemorrhage... - Risk factors for delirium tremens developmentJ A Ferguson
Department of Medicine, Indiana University School of Medicine, Indianapolis, USA
J Gen Intern Med 11:410-4. 1996..CONCLUSIONS: Inpatient development of delirium tremens was common among patients treated for alcohol detoxification or withdrawal and correlated with several readily available clinical variables... - Comparing correlated areas under the ROC curves of two diagnostic tests in the presence of verification biasX H Zhou
Department of Medicine, Indiana University School of Medicine, Indianapolis 46202 5119, USA
Biometrics 54:453-70. 1998..We also develop an approach for testing the validity of the MAR assumption. Finally, we use the proposed method to compare the relative accuracies of MRI and CT in evaluation of pancreatic cancer... - Similar effectiveness of paroxetine, fluoxetine, and sertraline in primary care: a randomized trialK Kroenke
Regenstrief Institute for Health Care, Indianapolis, IN, USA
JAMA 286:2947-55. 2001..Selective serotonin reuptake inhibitors (SSRIs) are the most commonly prescribed class of antidepressant, yet it is not known whether one SSRI is more effective than another... - Using electronic medical records to predict mortality in primary care patients with heart disease: prognostic power and pathophysiologic implicationsW M Tierney
Department of Medicine, Indiana University School of Medicine, Indianapolis, Indiana, USA
J Gen Intern Med 11:83-91. 1996..This could allow increasingly scarce health care resources to be focused on those at highest mortality risk... - Nonparametric estimation of ROC curves in the absence of a gold standardXiao Hua Zhou
HSR and D VA Puget Sound Health Care System, Seattle, Washington 98101, USA
Biometrics 61:600-9. 2005..Finally, we illustrate the application of the proposed method in a real clinical study on assessing the accuracy of seven specific pathologists in detecting carcinoma in situ of the uterine cervix... - Quantifying risk of adverse clinical events with one set of vital signs among primary care patients with hypertensionWilliam M Tierney
Indiana University School of Medicine, Indianapolis, Ind, USA
Ann Fam Med 2:209-17. 2004..Hypertension is often uncontrolled. One reason might be physicians' reticence to modify therapy in response to single office measurements of vital signs... - Failure of computerized treatment suggestions to improve health outcomes of outpatients with uncomplicated hypertension: results of a randomized controlled trialMichael D Murray
Department of Medicine, Indiana University School of Medicine, USA
Pharmacotherapy 24:324-37. 2004..To assess the effects of evidence-based treatment suggestions for hypertension made to physicians and pharmacists using a comprehensive electronic medical record system... 
A computer program for estimating the re-transformed mean in heteroscedastic two-part modelsXiao Hua Zhou
VA Puget Sound Health Care System, Seattle, WA 98108, USA
Comput Methods Programs Biomed 90:210-6. 2008..Our program included user-friendly interactive mode and more efficient and flexible batch mode. It was written in free statistical computing language R and could be run on a wide variety of platforms...- A controlled trial of including symptom data in computer-based care suggestions for managing patients with chronic heart failureUsha Subramanian
Division of General Internal Medicine, Department of Medicine, Indiana University School of Medicine, Indianapolis, Indiana, USA
Am J Med 116:375-84. 2004..3 vs. 1.7 hospitalizations, P = 0.05). CONCLUSION: Adding symptom information to computer-generated care suggestions for patients with heart failure did not affect physician treatment decisions or improve patient outcomes... - Effects of computerized guidelines for managing heart disease in primary careWilliam M Tierney
Regenstrief Institute for Health Care, Indiana University School of Medicine, Indianapolis, Indiana, USA
J Gen Intern Med 18:967-76. 2003..Electronic information systems have been proposed as one means to reduce medical errors of commission (doing the wrong thing) and omission (not providing indicated care)... - The need for reorientation toward cost-effective prediction: comments on 'Evaluating the added predictive ability of a new marker: From area under the ROC curve to reclassification and beyond' by Pencina et al., Statistics in Medicine (DOI: 10.1002/sim.29Yueh-Yun Chi
Department of Biostatistics, University of Washington, Seattle, WA 98101, USA
Stat Med 27:182-4. 2008 - Assessing the adequacy of variance function in heteroscedastic regression modelsLan Wang
School of Statistics, University of Minnesota, 224 Church Street SE, Minneapolis, Minnesota 55455, USA
Biometrics 63:1218-25. 2007..Numerical simulations demonstrate the satisfactory performance of the proposed test. We also illustrate the application by the analysis of a radioimmunoassay data set... - Wilcoxon-based group sequential designs for comparison of areas under two correlated ROC curvesXiao Hua Zhou
HSR and D Center of Excellence, VA Puget Sound Health Care System, Seattle, WA 98108, USA
Stat Med 27:213-23. 2008..The adoption of GSDs may lead to substantial savings in the number of required cases, thus resulting in both time and resource use efficiency... - Empirical likelihood inference for the area under the ROC curveGengsheng Qin
Department of Mathematics and Statistics, Georgia State University, Atlanta, Georgia 30303, USA
Biometrics 62:613-22. 2006..Additionally we conduct simulation studies to compare the relative performance of the proposed EL-based interval with the existing normal approximation-based intervals and bootstrap intervals for the AUC... - Nonparametric statistical methods for cost-effectiveness analysesPhillip Dinh
Department of Biostatistics, University of Washington, Box 357232, Seattle, Washington 98195, USA
Biometrics 62:576-88. 2006..We found that our new intervals give good coverage accuracy and are narrower compared to the current recommended intervals... - Interval estimates for the ratio and difference of two lognormal meansYea Hung Chen
Department of Biostatistics, University of Washington, Seattle WA 98195, USA
Stat Med 25:4099-113. 2006..Additionally, we provide and discuss the results of a series of computer simulations. Finally, the techniques are applied to a real example... - Multiple imputation for correcting verification biasOfer Harel
Department of Statistics, University of Connecticut, 215 Glenbrook Road Unit 4120 Storrs, CT 06269 4120, USA
Stat Med 25:3769-86. 2006..We show that our imputation methods are better than the existing methods with regard to nominal coverage and confidence interval length... - New confidence intervals for the difference between two sensitivities at a fixed level of specificityGengsheng Qin
Department of Mathematics and Statistics, Georgia State University, University Plaza Atlanta, GA 30303, USA
Stat Med 25:3487-502. 2006..Our simulation results show that the newly proposed intervals perform better than the existing normal-approximation-based interval in terms of coverage accuracy and interval length... - ITT analysis of randomized encouragement design studies with missing dataXiao-Hua Zhou
Veterans Affairs Puget Sound Health Care System, Metropolitan Park West, 1100 Olive Way # 1400, Seattle, WA, USA
Stat Med 25:2737-61. 2006..We illustrated our methods in a randomized encouragement design study on the effectiveness of flu shots... - Can computer-generated evidence-based care suggestions enhance evidence-based management of asthma and chronic obstructive pulmonary disease? A randomized, controlled trialWilliam M Tierney
Department of Medicine, Indiana University School of Medicine, M200 OPW, Wishard Memorial Hospital, 1001 West 10th St, Indianapolis, IN 46202, USA
Health Serv Res 40:477-97. 2005..Translation of evidence-based guidelines into clinical practice has been inconsistent. We performed a randomized, controlled trial of guideline-based care suggestions delivered to physicians when writing orders on computer workstations... - Improved confidence intervals for the sensitivity at a fixed level of specificity of a continuous-scale diagnostic testXiao Hua Zhou
Biostatistics Unit, Health Services Research and Development Center of Excellence, Building 1, Rm 424, Veterans Affairs Puget Sound Health Care System, 1660 S Columbian Way, Seattle, WA 98108, USA
Stat Med 24:465-77. 2005..Our simulation results show that the newly proposed intervals are better than the BCa bootstrap interval in terms of coverage accuracy and interval length... - Bootstrap confidence intervals for medical costs with censored observationsHongyu Jiang
Department of Biostatistics, Harvard School of Public Health, Boston, MA 02115, USA
Stat Med 23:3365-76. 2004..We also illustrate the use of our methods in a real example... - Using alcohol screening results and treatment history to assess the severity of at-risk drinking in Veterans Affairs primary care patientsKatharine A Bradley
Northwest Health Services Research and Development Center of Excellence, Primary and Specialty Medical Care Service, VA Puget Sound Health Care System, Seattle, WA 98108, USA
Alcohol Clin Exp Res 28:448-55. 2004..We evaluated whether scores on brief alcohol screening questionnaires and patient reports of prior alcohol treatment reflect the severity of recent problems due to drinking...