Karmen K Yoder

Summary

Affiliation: Indiana University
Country: USA

Publications

  1. pmc Influence of TSPO genotype on 11C-PBR28 standardized uptake values
    Karmen K Yoder
    Department of Radiology and Imaging Sciences, Indiana University School of Medicine, Indianapolis, Indiana 46202, USA
    J Nucl Med 54:1320-2. 2013
  2. pmc Test-retest variability of [¹¹C]raclopride-binding potential in nontreatment-seeking alcoholics
    Karmen K Yoder
    Indiana University Center for Neuroimaging, Indiana University School of Medicine, Indianapolis, IN 46202, USA
    Synapse 65:553-61. 2011
  3. doi request reprint Assessment of i.p. injection of [18F]fallypride for behavioral neuroimaging in rats
    Karmen K Yoder
    Department of Radiology and Imaging Sciences, Indiana University School of Medicine, R2 E124, 950 W Walnut St, Indianapolis, IN 46202, USA
    J Neurosci Methods 196:70-5. 2011
  4. ncbi request reprint Reliability of striatal [¹¹C]raclopride binding in smokers wearing transdermal nicotine patches
    Karmen K Yoder
    Indiana University Center for Neuroimaging, Indiana University School of Medicine, Indianapolis, IN, USA
    Eur J Nucl Med Mol Imaging 39:220-5. 2012
  5. pmc What were they thinking? Cognitive states may influence [11C]raclopride binding potential in the striatum
    Karmen K Yoder
    Department of Radiology, Indiana University School of Medicine, Indianapolis, IN, United States
    Neurosci Lett 430:38-42. 2008
  6. ncbi request reprint Heterogeneous effects of alcohol on dopamine release in the striatum: a PET study
    Karmen K Yoder
    Department of Radiology, Indiana University School of Medicine, Indianapolis, Indiana, USA
    Alcohol Clin Exp Res 31:965-73. 2007
  7. ncbi request reprint Dopamine D(2) receptor availability is associated with subjective responses to alcohol
    Karmen K Yoder
    Department of Radiology, Division of Research, Section of Imaging Sciences, Indiana University School of Medicine, Indianapolis, IN 46206, USA
    Alcohol Clin Exp Res 29:965-70. 2005
  8. ncbi request reprint Dopamine transporter density in schizophrenic subjects with and without tardive dyskinesia
    Karmen K Yoder
    Department of Radiology, Division of Research, Section of Imaging Science, 950 W Walnut St, Research Institute 2, Room E124, Indianapolis, IN 46202, USA
    Schizophr Res 71:371-5. 2004
  9. ncbi request reprint Change in binding potential as a quantitative index of neurotransmitter release is highly sensitive to relative timing and kinetics of the tracer and the endogenous ligand
    Karmen K Yoder
    Department of Radiology, Indiana University School of Medicine, Indianapolis, Indiana, USA
    J Nucl Med 45:903-11. 2004
  10. ncbi request reprint ntPET: a new application of PET imaging for characterizing the kinetics of endogenous neurotransmitter release
    Evan D Morris
    Indiana University School of Medicine, Indianapolis, USA
    Mol Imaging 4:473-89. 2005

Collaborators

Detail Information

Publications26

  1. pmc Influence of TSPO genotype on 11C-PBR28 standardized uptake values
    Karmen K Yoder
    Department of Radiology and Imaging Sciences, Indiana University School of Medicine, Indianapolis, Indiana 46202, USA
    J Nucl Med 54:1320-2. 2013
    ..However, it is not known whether standardized uptake value (SUV) can detect differences in brain (11)C-PBR28 uptake by TSPO genotype...
  2. pmc Test-retest variability of [¹¹C]raclopride-binding potential in nontreatment-seeking alcoholics
    Karmen K Yoder
    Indiana University Center for Neuroimaging, Indiana University School of Medicine, Indianapolis, IN 46202, USA
    Synapse 65:553-61. 2011
    ..The results demonstrate that baseline striatal RAC binding is highly reproducible in NTS subjects, with a low variance similar to that reported for healthy control subjects...
  3. doi request reprint Assessment of i.p. injection of [18F]fallypride for behavioral neuroimaging in rats
    Karmen K Yoder
    Department of Radiology and Imaging Sciences, Indiana University School of Medicine, R2 E124, 950 W Walnut St, Indianapolis, IN 46202, USA
    J Neurosci Methods 196:70-5. 2011
    ..p. injection. However, this was not seen consistently across animals. Future studies are needed to validate, and then to optimize, the use of i.p. FAL for behavioral imaging protocols...
  4. ncbi request reprint Reliability of striatal [¹¹C]raclopride binding in smokers wearing transdermal nicotine patches
    Karmen K Yoder
    Indiana University Center for Neuroimaging, Indiana University School of Medicine, Indianapolis, IN, USA
    Eur J Nucl Med Mol Imaging 39:220-5. 2012
    ..Thus, we sought to determine the test-retest reliability of RAC binding in the presence of nicotine patches...
  5. pmc What were they thinking? Cognitive states may influence [11C]raclopride binding potential in the striatum
    Karmen K Yoder
    Department of Radiology, Indiana University School of Medicine, Indianapolis, IN, United States
    Neurosci Lett 430:38-42. 2008
    ..Our findings suggest that even slight differences in cognitive states between groups can have an effect on BP(ND), presumably mediated by changes in endogenous dopamine concentration...
  6. ncbi request reprint Heterogeneous effects of alcohol on dopamine release in the striatum: a PET study
    Karmen K Yoder
    Department of Radiology, Indiana University School of Medicine, Indianapolis, Indiana, USA
    Alcohol Clin Exp Res 31:965-73. 2007
    ..Our approach was to identify voxels that exhibited alcohol-induced DA responses within the striatum, and to determine the relationships between DA responses and alcohol-related behavior...
  7. ncbi request reprint Dopamine D(2) receptor availability is associated with subjective responses to alcohol
    Karmen K Yoder
    Department of Radiology, Division of Research, Section of Imaging Sciences, Indiana University School of Medicine, Indianapolis, IN 46206, USA
    Alcohol Clin Exp Res 29:965-70. 2005
    ..Here, we examined the relationship between dopamine D2 receptors in the nucleus accumbens and scores of perceived "high" and "intoxication" during an intravenous (IV) alcohol infusion...
  8. ncbi request reprint Dopamine transporter density in schizophrenic subjects with and without tardive dyskinesia
    Karmen K Yoder
    Department of Radiology, Division of Research, Section of Imaging Science, 950 W Walnut St, Research Institute 2, Room E124, Indianapolis, IN 46202, USA
    Schizophr Res 71:371-5. 2004
    ..Significant and trend-level inverse correlations were found between DAT BP in the striatum, and especially the severity of negative symptom scores, but also cognitive, and depression/anxiety scores on the PANSS...
  9. ncbi request reprint Change in binding potential as a quantitative index of neurotransmitter release is highly sensitive to relative timing and kinetics of the tracer and the endogenous ligand
    Karmen K Yoder
    Department of Radiology, Indiana University School of Medicine, Indianapolis, Indiana, USA
    J Nucl Med 45:903-11. 2004
    ..We sought to characterize the sensitivity of deltaBP to changes in endogenous DA concentration and to elucidate possible biases in deltaBP with respect to timing of task-induced or drug-induced increases in DA...
  10. ncbi request reprint ntPET: a new application of PET imaging for characterizing the kinetics of endogenous neurotransmitter release
    Evan D Morris
    Indiana University School of Medicine, Indianapolis, USA
    Mol Imaging 4:473-89. 2005
    ..Finally, we applied the ntPET method to small-animal imaging data in order to produce the first noninvasive assay of the time-varying release of dopamine in the rat striatum following alcohol...
  11. pmc When what you see isn't what you get: alcohol cues, alcohol administration, prediction error, and human striatal dopamine
    Karmen K Yoder
    Department of Radiology, Indiana University School of Medicine, Indianapolis, IN, USA
    Alcohol Clin Exp Res 33:139-49. 2009
    ..This study assessed the distinct effects of alcohol-related cues and alcohol administration on striatal DA release in healthy humans...
  12. doi request reprint An improved synthesis of dopamine D2/D3 receptor radioligands [11C]fallypride and [18F]fallypride
    Mingzhang Gao
    Department of Radiology, Indiana University School of Medicine, 1345 West 16th Street, L 3 Room 202, Indianapolis, IN 46202, USA
    Appl Radiat Isot 68:1079-86. 2010
    ..2.2 and HPLC combined with solid-phase extraction (SPE) purification in variable (up to 50%) decay corrected radiochemical yield from K[(18)F]F and 111-222 GBq/micromol specific activity at EOB...
  13. pmc Imaging of alcohol-induced dopamine release in rats:preliminary findings with [(11) C]raclopride PET
    Jenna M Sullivan
    Department of Biomedical Engineering, Purdue University, West Lafayette, Indiana, USA
    Synapse 65:929-37. 2011
    ..v. alcohol administration and those who had not. Preliminary results suggest that alcohol-induced DA release in the rat striatum is detectable using small animal PET given sufficiently large cohorts and adequate blood alcohol levels...
  14. pmc Association of plasma and cortical amyloid beta is modulated by APOE ε4 status
    Shanker Swaminathan
    Center for Neuroimaging, Department of Radiology and Imaging Sciences, Indiana University School of Medicine, Indianapolis, IN, USA Department of Medical and Molecular Genetics, Indiana University School of Medicine, Indianapolis, IN, USA
    Alzheimers Dement 10:e9-e18. 2014
    ....
  15. pmc Beer flavor provokes striatal dopamine release in male drinkers: mediation by family history of alcoholism
    Brandon G Oberlin
    Department of Neurology, Indiana University School of Medicine, Indianapolis, IN 46202, USA
    Neuropsychopharmacology 38:1617-24. 2013
    ..Striatal DA responses to salient alcohol cues may thus be an inherited risk factor for alcoholism. ..
  16. pmc Fully automated synthesis and initial PET evaluation of [11C]PBR28
    Min Wang
    Department of Radiology, Indiana University School of Medicine, 950 West Walnut Street, Room 427, Indianapolis, IN 46202, USA
    Bioorg Med Chem Lett 19:5636-9. 2009
    ..These results facilitate the potential preclinical and clinical PET studies of [11C]PBR28 in animals and humans...
  17. pmc A rat head holder for simultaneous scanning of two rats in small animal PET scanners: design, construction, feasibility testing and kinetic validation
    Tee Ean Cheng
    Biomedical Engineering Department, Purdue School of Engineering and Technology, Indianapolis, IN 46202, USA
    J Neurosci Methods 176:24-33. 2009
    ..To reduce imaging costs, we designed a head holder for scanning two rats simultaneously in small animal PET scanners. Our goals were (i) to maintain high sensitivity and (ii) to minimize repositioning error between scans...
  18. pmc Striatal D(2)/D(3) receptor availability is inversely correlated with cannabis consumption in chronic marijuana users
    Daniel S Albrecht
    Indiana University Center for Neuroimaging, Indiana University School of Medicine, Indianapolis, IN 46202, USA
    Drug Alcohol Depend 128:52-7. 2013
    ..Imaging studies have demonstrated deficits in striatal D(2)/D(3) receptor availability in several substance-dependent populations. However, this has not been studied in currently using chronic cannabis users...
  19. pmc Effects of smoking on D₂/D₃ striatal receptor availability in alcoholics and social drinkers
    Daniel S Albrecht
    Department of Radiology and Imaging Sciences, Indiana University School of Medicine, R2 E124, 950 W Walnut St, Indianapolis, IN, 46202, USA
    Brain Imaging Behav 7:326-34. 2013
    ..Additional studies are needed to identify the mechanisms by which chronic tobacco smoking is associated with striatal dopamine receptor availability...
  20. pmc Amyloid pathway-based candidate gene analysis of [(11)C]PiB-PET in the Alzheimer's Disease Neuroimaging Initiative (ADNI) cohort
    Shanker Swaminathan
    Department of Radiology and Imaging Sciences, Center for Neuroimaging, Indiana University School of Medicine, Indianapolis, IN, USA
    Brain Imaging Behav 6:1-15. 2012
    ..Pathway-based genetic analysis of targeted molecular imaging phenotypes appears promising to help elucidate disease pathophysiology and identify potential therapeutic targets...
  21. ncbi request reprint Striatal dopamine transporter availability in unmedicated bipolar disorder
    Amit Anand
    Department of Psychiatry, Indiana University School of Medicine, Indianapolis, IN, USA
    Bipolar Disord 13:406-13. 2011
    ..This positron emission tomography (PET) study investigated whether DAT availability differed between BPD and healthy control subjects...
  22. doi request reprint Dopamine transporter binding in rat striatum: a comparison of [O-methyl-11C]beta-CFT and [N-methyl-11C]beta-CFT
    Karmen K Yoder
    Department of Radiology, Indiana University School of Medicine, L3 208, Indianapolis, IN 46202, USA
    Nucl Med Biol 36:11-6. 2009
    ..In this study, we sought to validate that the O-methylated form of [(11)C]beta-CFT provides equivalent quantitative results to that of the more commonly reported N-methyl form...
  23. ncbi request reprint Positron emission tomography displacement sensitivity: predicting binding potential change for positron emission tomography tracers based on their kinetic characteristics
    Evan D Morris
    Biomedical Engineering Department, Purdue School of Engineering and Technology, Indiana University Purdue University at Indianapolis, Indianapolis, IN 46202, USA
    J Cereb Blood Flow Metab 27:606-17. 2007
    ..The values are in good agreement with the PDS-predicted rank order of sensitivity to displacement...
  24. ncbi request reprint Cortical dopamine release during a behavioral response inhibition task
    Daniel S Albrecht
    Department of Radiology and Imaging Sciences, Indiana University School of Medicine, Indianapolis, Indiana, 46202 Stark Neurosciences Research Institute, Indiana University School of Medicine, Indianapolis, Indiana, 46202
    Synapse 68:266-74. 2014
    ..These data support the feasibility of using FAL PET to study DA release during response inhibition, enabling investigation of relationships between DA function and impulsive behavior...
  25. ncbi request reprint A supervised method for calculating perfusion/diffusion mismatch volume in acute ischemic stroke
    Judy R James
    Department of Biomedical Engineering, Indiana University Purdue University, IUPUI Indianapolis, IN, USA
    Comput Biol Med 36:1268-87. 2006
    ..Clinical data show that raters using our tool are consistent, fast (15min per subject) and indistinguishable from an expert using manual segmentation...
  26. ncbi request reprint Estimation of local receptor density, B'max, and other parameters via multiple-injection positron emission tomography experiments
    Evan D Morris
    Department of Radiology, Indiana University School of Medicine, Indianapolis, IN 46202, USA
    Methods Enzymol 385:184-213. 2004