X Xuei

Summary

Affiliation: Indiana University
Country: USA

Publications

  1. pmc Microarray studies on effects of Pneumocystis carinii infection on global gene expression in alveolar macrophages
    Bi Hua Cheng
    Department of Obstetrics and Gynecology, Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Kaohsiung, Taiwan
    BMC Microbiol 10:103. 2010
  2. pmc GABRR1 and GABRR2, encoding the GABA-A receptor subunits rho1 and rho2, are associated with alcohol dependence
    Xiaoling Xuei
    Department of Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis, IN 46202, USA
    Am J Med Genet B Neuropsychiatr Genet 153:418-27. 2010
  3. ncbi request reprint Association analysis of genes encoding the nociceptin receptor (OPRL1) and its endogenous ligand (PNOC) with alcohol or illicit drug dependence
    Xiaoling Xuei
    Department of Biochemistry and Molecular Biology, Indiana Unviersity School of Medicine, Indianapolis, IN 46202, USA
    Addict Biol 13:80-7. 2008
  4. ncbi request reprint Use of SAM2 biotin capture membrane in microarrayed compound screening (muARCS) format for nucleic acid polymerization assays
    Xiaoling Xuei
    Global Pharmaceutical R and D, Abbott Laboratories, Abbott Park, IL, USA
    J Biomol Screen 8:273-82. 2003
  5. ncbi request reprint The opioid system in alcohol and drug dependence: family-based association study
    Xiaoling Xuei
    Indiana University School of Medicine, 1345 W 16th Street, Indianapolis, IN 46202, USA
    Am J Med Genet B Neuropsychiatr Genet 144:877-84. 2007
  6. ncbi request reprint Association of the kappa-opioid system with alcohol dependence
    X Xuei
    Department of Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis, IN 46202, USA
    Mol Psychiatry 11:1016-24. 2006
  7. pmc Association studies of ALOX5 and bone mineral density in healthy adults
    T Foroud
    Indiana University School of Medicine, Health Information and Translational Sciences Building, Indianapolis, IN 46202 3002, USA
    Osteoporos Int 19:637-43. 2008
  8. ncbi request reprint No association of the GABAA receptor genes on chromosome 5 with alcoholism in the collaborative study on the genetics of alcoholism sample
    Danielle M Dick
    Department of Medical and Molecular Genetics, Indiana University School of Medicine, 975 West Walnut St, Indianapolis, IN 46202 525, USA
    Am J Med Genet B Neuropsychiatr Genet 132:24-8. 2005
  9. ncbi request reprint Transcriptional changes in alveolar macrophages during Pneumocystis pneumonia
    Chao Hung Lee
    Dept of Pathology and Laboratory Medicine, Indiana University School of Medicine, Indianapolis, IN 46202, USA
    J Eukaryot Microbiol 50:645. 2003
  10. ncbi request reprint Association of NFKB1, which encodes a subunit of the transcription factor NF-kappaB, with alcohol dependence
    Howard J Edenberg
    Indiana University School of Medicine, Indianapolis, IN, USA
    Hum Mol Genet 17:963-70. 2008

Collaborators

Detail Information

Publications35

  1. pmc Microarray studies on effects of Pneumocystis carinii infection on global gene expression in alveolar macrophages
    Bi Hua Cheng
    Department of Obstetrics and Gynecology, Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Kaohsiung, Taiwan
    BMC Microbiol 10:103. 2010
    ....
  2. pmc GABRR1 and GABRR2, encoding the GABA-A receptor subunits rho1 and rho2, are associated with alcohol dependence
    Xiaoling Xuei
    Department of Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis, IN 46202, USA
    Am J Med Genet B Neuropsychiatr Genet 153:418-27. 2010
    ..04), and a haplotype in GABRR2 was significantly overtransmitted to family members who met a broader definition of alcoholism (P = 0.002) as well as DSM-IV dependence (P = 0.04)...
  3. ncbi request reprint Association analysis of genes encoding the nociceptin receptor (OPRL1) and its endogenous ligand (PNOC) with alcohol or illicit drug dependence
    Xiaoling Xuei
    Department of Biochemistry and Molecular Biology, Indiana Unviersity School of Medicine, Indianapolis, IN 46202, USA
    Addict Biol 13:80-7. 2008
    ..04-0.05). Secondary analyses suggested that two adjacent SNPs in intron 1 of OPRL1 were marginally associated with opioid dependence (P = 0.05); none of the SNPs in PNOC were associated with opioid dependence...
  4. ncbi request reprint Use of SAM2 biotin capture membrane in microarrayed compound screening (muARCS) format for nucleic acid polymerization assays
    Xiaoling Xuei
    Global Pharmaceutical R and D, Abbott Laboratories, Abbott Park, IL, USA
    J Biomol Screen 8:273-82. 2003
    ..The sensitivity for the known inhibitors appears to be comparable in muARCS as in a traditional 96-well plate assay. The methodology described in this paper further expands the applications of muARCS technology...
  5. ncbi request reprint The opioid system in alcohol and drug dependence: family-based association study
    Xiaoling Xuei
    Indiana University School of Medicine, 1345 W 16th Street, Indianapolis, IN 46202, USA
    Am J Med Genet B Neuropsychiatr Genet 144:877-84. 2007
    ....
  6. ncbi request reprint Association of the kappa-opioid system with alcohol dependence
    X Xuei
    Department of Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis, IN 46202, USA
    Mol Psychiatry 11:1016-24. 2006
    ....
  7. pmc Association studies of ALOX5 and bone mineral density in healthy adults
    T Foroud
    Indiana University School of Medicine, Health Information and Translational Sciences Building, Indianapolis, IN 46202 3002, USA
    Osteoporos Int 19:637-43. 2008
    ..We tested this hypothesis in a sample of healthy men and women and did not find consistent evidence for an association between variation in this gene and either lumbar spine or femoral neck BMD...
  8. ncbi request reprint No association of the GABAA receptor genes on chromosome 5 with alcoholism in the collaborative study on the genetics of alcoholism sample
    Danielle M Dick
    Department of Medical and Molecular Genetics, Indiana University School of Medicine, 975 West Walnut St, Indianapolis, IN 46202 525, USA
    Am J Med Genet B Neuropsychiatr Genet 132:24-8. 2005
    ..Future studies are planned to test whether these genes are more important in influencing behavioral endophenotypes related to the risk of alcohol dependence...
  9. ncbi request reprint Transcriptional changes in alveolar macrophages during Pneumocystis pneumonia
    Chao Hung Lee
    Dept of Pathology and Laboratory Medicine, Indiana University School of Medicine, Indianapolis, IN 46202, USA
    J Eukaryot Microbiol 50:645. 2003
  10. ncbi request reprint Association of NFKB1, which encodes a subunit of the transcription factor NF-kappaB, with alcohol dependence
    Howard J Edenberg
    Indiana University School of Medicine, Indianapolis, IN, USA
    Hum Mol Genet 17:963-70. 2008
    ..Thus, variations in NFKB1 appear to affect the risk for alcoholism, particularly contributing to an earlier onset of the disease...
  11. pmc A regulatory variation in OPRK1, the gene encoding the kappa-opioid receptor, is associated with alcohol dependence
    Howard J Edenberg
    Department of Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis, IN 46202, USA
    Hum Mol Genet 17:1783-9. 2008
    ..This indel is, therefore, a functional regulatory variation likely to explain at least part of the association of OPRK1 with alcohol dependence...
  12. pmc The tachykinin receptor 3 is associated with alcohol and cocaine dependence
    Tatiana Foroud
    Indiana University School of Medicine, Indianapolis, Indiana 46202 3002, USA
    Alcohol Clin Exp Res 32:1023-30. 2008
    ..Pharmacological studies have provided evidence that the administration of NK3R agonists attenuates the intake of alcohol and NK3R can also mediate the acute and chronic behavioral effects of cocaine...
  13. pmc Identification of a linkage disequilibrium block in chromosome 1q associated with BMD in premenopausal white women
    Shoji Ichikawa
    Department of Medicine, Indiana University School of Medicine, Indianapolis, Indiana 46202 5121, USA
    J Bone Miner Res 23:1680-8. 2008
    ....
  14. pmc CLCN7 polymorphisms and bone mineral density in healthy premenopausal white women and in white men
    Kang Chu
    Department of Medicine, Indiana University School of Medicine, Indianapolis, IN 46202, USA
    Bone 43:995-8. 2008
    ..However, there is no study to date that has examined whether CLCN7 polymorphisms underlie normal variation of peak BMD in healthy premenopausal white women and in white men...
  15. pmc Neuropeptide Y receptor genes are associated with alcohol dependence, alcohol withdrawal phenotypes, and cocaine dependence
    Leah Wetherill
    Indiana University School of Medicine, Indianapolis, Indiana 46202, USA
    Alcohol Clin Exp Res 32:2031-40. 2008
    ..Additional studies suggest that cocaine may affect NPY expression...
  16. pmc Association of adenylate cyclase 10 (ADCY10) polymorphisms and bone mineral density in healthy adults
    Shoji Ichikawa
    Department of Medicine, Indiana University School of Medicine, 541 North Clinical Drive, Clinical Building 459, Indianapolis, IN 46202 5121, USA
    Calcif Tissue Int 84:97-102. 2009
    ..However, adjacent SNPs did not corroborate the association in either men or women. In conclusion, we found a modest association between an ADCY10 polymorphism and the spinal areal BMD in premenopausal white women...
  17. pmc Genome-wide association study of bone mineral density in premenopausal European-American women and replication in African-American women
    Daniel L Koller
    Departments of Medical and Molecular Genetics, Indiana University School of Medicine, Indianapolis, Indiana 46202, USA
    J Clin Endocrinol Metab 95:1802-9. 2010
    ..Several genome-wide association studies (GWAS) have been performed to identify genes contributing to bone mineral density (BMD), typically in samples of elderly women and men...
  18. pmc Genome-wide association study of alcohol dependence implicates a region on chromosome 11
    Howard J Edenberg
    Department of Biochemistry, Indiana University School of Medicine, Indianapolis, 46202 5122, USA
    Alcohol Clin Exp Res 34:840-52. 2010
    ..Alcohol dependence is a complex disease, and although linkage and candidate gene studies have identified several genes associated with the risk for alcoholism, these explain only a portion of the risk...
  19. ncbi request reprint Contribution of the LRP5 gene to normal variation in peak BMD in women
    Daniel L Koller
    Department of Medical and Molecular Genetics, Indiana University School of Medicine, Indianapolis, Indiana 46202, USA
    J Bone Miner Res 20:75-80. 2005
    ..Association between SNPs in LRP5 and hip and spine BMD was measured in 1301 premenopausal women. Only a small proportion of the BMD variation was attributable to LRP5 in our sample...
  20. ncbi request reprint Lack of association of alcohol dependence and habitual smoking with catechol-O-methyltransferase
    Tatiana Foroud
    Indiana University School of Medicine, Indianapolis, Indiana 46202 3002, USA
    Alcohol Clin Exp Res 31:1773-9. 2007
    ....
  21. ncbi request reprint Searching for hemostatic modifier genes affecting the phenotype of mice with very low levels of FVII
    Elliot D Rosen
    Medical and Molecular Genetics, Indiana University School of Medicine, 975 W Walnut Street, IB130, Indianapolis, IN 46202, USA
    Blood Cells Mol Dis 36:131-4. 2006
    ..A SNP genomic scan was performed on DNA from long-term surviving FVII(tTA/-) mice. The scan identified 8 regions enriched for 129x1/SVJ sequences that might contain putative hemostatic modifier genes...
  22. ncbi request reprint Association of alcohol dehydrogenase genes with alcohol dependence: a comprehensive analysis
    Howard J Edenberg
    Indiana University School of Medicine, Indianapolis, USA
    Hum Mol Genet 15:1539-49. 2006
    ..01) There was weaker evidence that variations in ADH1A and ADH1B might also play a role in modifying risk. Among African-Americans, there was evidence that the ADH1B*3 allele was protective...
  23. pmc Variations in GABRA2, encoding the alpha 2 subunit of the GABA(A) receptor, are associated with alcohol dependence and with brain oscillations
    Howard J Edenberg
    Indiana University School of Medicine, Indianapolis 46202, USA
    Am J Hum Genet 74:705-14. 2004
    ....
  24. ncbi request reprint Association of alcohol craving with alpha-synuclein (SNCA)
    Tatiana Foroud
    Indiana University School of Medicine, Indianapolis, Indiana 46202 5251, USA
    Alcohol Clin Exp Res 31:537-45. 2007
    ..Studies in humans have provided support for an association between SNCA and craving for alcohol...
  25. ncbi request reprint Association of GABRG3 with alcohol dependence
    Danielle M Dick
    Indiana University School of Medicine, Indianapolis, Indiana, USA
    Alcohol Clin Exp Res 28:4-9. 2004
    ..Both linkage and association to the region on chromosome 15q that contains a cluster of GABAA receptor genes have previously been reported, but the role of these genes in alcoholism remains inconclusive...
  26. ncbi request reprint Human ALOX12, but not ALOX15, is associated with BMD in white men and women
    Shoji Ichikawa
    Department of Medicine, Indiana University School of Medicine, Indianapolis, Indiana 46202 5121, USA
    J Bone Miner Res 21:556-64. 2006
    ..Polymorphisms in human ALOX12, but not ALOX15, were significantly associated with spine BMD in white men and women, suggesting that ALOX12 may contribute to normal variation in BMD...
  27. pmc Evidence of association between brain-derived neurotrophic factor gene and bipolar disorder
    Lixiang Liu
    Indiana University, Indianapolis, Indiana 46202 3002, USA
    Psychiatr Genet 18:267-74. 2008
    ..Growing evidence suggests that BDNF is involved in the pathophysiology of mood disorders...
  28. pmc Novel antibacterial class
    Peter J Dandliker
    Global Pharmaceutical Research and Development, Abbott Laboratories, Abbott Park, Illinois 60064, USA
    Antimicrob Agents Chemother 47:3831-9. 2003
    ..The NRIs are a promising new antibacterial class with activity against all major drug-resistant respiratory pathogens...
  29. ncbi request reprint Polymorphisms in the bone morphogenetic protein 2 (BMP2) gene do not affect bone mineral density in white men or women
    S Ichikawa
    Department of Medicine, Indiana University School of Medicine, Indianapolis, IN, USA
    Osteoporos Int 17:587-92. 2006
    ..Recently, bone morphogenetic protein 2 (BMP2) was reported as a susceptibility gene for osteoporotic fractures and low BMD in Icelandic and Danish populations...
  30. pmc Association of the calcium-sensing receptor gene with blood pressure and urinary calcium in African-Americans
    JeeSun Jung
    Department of Medical and Molecular Genetics, Indiana University School of Medicine, Indianapolis, Indiana 46202, USA
    J Clin Endocrinol Metab 94:1042-8. 2009
    ..CASR gene variants could influence blood pressure (BP) by affecting Na retention...
  31. ncbi request reprint A strategy for discovery of novel broad-spectrum antibacterials using a high-throughput Streptococcus pneumoniae transcription/translation screen
    Steven D Pratt
    Global Pharmaceutical Research and Development, Abbott Laboratories, Abbott Park, IL 60064 6217, USA
    J Biomol Screen 9:3-11. 2004
    ..One of these compounds had the desired profile of broad-spectrum biochemical activity in bacteria and selectivity versus mammalian biochemical and whole-cell assays...
  32. ncbi request reprint The role of GABRA2 in risk for conduct disorder and alcohol and drug dependence across developmental stages
    Danielle M Dick
    Department of Psychiatry and Psychology, Washington University School of Medicine, St Louis, MO 63110, USA
    Behav Genet 36:577-90. 2006
    ..GABRA2 is also associated with other drug dependence in our sample, both in adolescence and adulthood...
  33. ncbi request reprint Association between GABRA1 and drinking behaviors in the collaborative study on the genetics of alcoholism sample
    Danielle M Dick
    Department of Psychiatry, Washington University School of Medicine, St Louis, Missouri 63110, USA
    Alcohol Clin Exp Res 30:1101-10. 2006
    ....
  34. doi request reprint A Systematic single nucleotide polymorphism screen to fine-map alcohol dependence genes on chromosome 7 identifies association with a novel susceptibility gene ACN9
    Danielle M Dick
    Washington University in St Louis, St Louis, Missouri, USA
    Biol Psychiatry 63:1047-53. 2008
    ..To follow up on this linkage region, we systematically screened single nucleotide polymorphisms (SNPs) across a 2 LOD support interval surrounding the alcohol dependence peak...
  35. pmc Variants in nicotinic receptors and risk for nicotine dependence
    Laura Jean Bierut
    Department of Psychiatry, Washington University School of Medicine, Box 8134, 660 South Euclid Ave, St Louis, MO 63110, USA
    Am J Psychiatry 165:1163-71. 2008
    ....