Xiao Ming Xu

Summary

Affiliation: Indiana University
Country: USA

Publications

  1. pmc Chondroitin sulfate proteoglycans regulate the growth, differentiation and migration of multipotent neural precursor cells through the integrin signaling pathway
    Wen Li Gu
    Department of Neurobiology, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, PR China
    BMC Neurosci 10:128. 2009
  2. pmc Transplantation-mediated strategies to promote axonal regeneration following spinal cord injury
    Xiao Ming Xu
    Spinal Cord and Brain Injury Research Group, Stark Neurosciences Research Institute, Indiana University School of Medicine, Indianapolis, IN 46202, United States
    Respir Physiol Neurobiol 169:171-82. 2009
  3. pmc A novel growth-promoting pathway formed by GDNF-overexpressing Schwann cells promotes propriospinal axonal regeneration, synapse formation, and partial recovery of function after spinal cord injury
    Ling Xiao Deng
    Spinal Cord and Brain Injury Research Group, Stark Neurosciences Research Institute, and Department of Neurological Surgery, Goodman and Campbell Brain and Spine, Indiana University School of Medicine, Indianapolis, Indiana 46202, USA
    J Neurosci 33:5655-67. 2013
  4. pmc GDNF modifies reactive astrogliosis allowing robust axonal regeneration through Schwann cell-seeded guidance channels after spinal cord injury
    Ling Xiao Deng
    Spinal Cord and Brain Injury Research Group, Stark Neurosciences Research Institute, Indiana University School of Medicine, Indianapolis, IN 46202, USA
    Exp Neurol 229:238-50. 2011
  5. doi request reprint A bilateral head injury that shows graded brain damage and behavioral deficits in adultmice
    Nai Kui Liu
    Spinal Cord and Brain Injury Research Group, Stark Neurosciences Research Institute, Department of Neurological Surgery and Goodman Campbell Brain and Spine, Indiana University School of Medicine, Indianapolis, IN 46202, USA
    Brain Res 1499:121-8. 2013
  6. pmc Systemic bisperoxovanadium activates Akt/mTOR, reduces autophagy, and enhances recovery following cervical spinal cord injury
    Chandler L Walker
    Department of Anatomy and Cell Biology, Stark Neurosciences Research Institute, Indiana University School of Medicine, Indianapolis, Indiana, United States of America
    PLoS ONE 7:e30012. 2012
  7. pmc Preferential and bidirectional labeling of the rubrospinal tract with adenovirus-GFP for monitoring normal and injured axons
    Xiaofei Wang
    Spinal Cord and Brain Injury Research Group, Stark Neurosciences Research Institute, and Department of Neurological Surgery, Indiana University School of Medicine, Indianapolis, Indiana 46202, USA
    J Neurotrauma 28:635-47. 2011
  8. pmc Altered microRNA expression following traumatic spinal cord injury
    Nai Kui Liu
    Spinal Cord and Brain Injury Research Group, Stark Neurosciences Research Institute and Department of Neurological Surgery, Indiana University School of Medicine, 950 W Walnut St, R 2 Building, Room 402, Indianapolis, IN 46202, USA
    Exp Neurol 219:424-9. 2009
  9. doi request reprint Phospholipase A2 and its molecular mechanism after spinal cord injury
    Nai Kui Liu
    Spinal Cord and Brain Injury Research Group, Stark Neurosciences Research Institute, Indiana University School of Medicine, 950 W Walnut St, R 2 Building, Room 402, Indianapolis, IN 46202, USA
    Mol Neurobiol 41:197-205. 2010

Collaborators

  • George M Smith
  • Xuejun Wen
  • Stephen M Onifer
  • Ping Deng
  • Nai Kui Liu
  • Ling Xiao Deng
  • Chandler L Walker
  • Xiaofei Wang
  • Qing Bo Lu
  • Wen Li Gu
  • Yiwen Ruan
  • Eddie Oakes
  • Alexander Gianaris
  • Yi Ping Zhang
  • Tom Verhovshek
  • Zao Cheng Xu
  • Jeremy O'Connor
  • Christopher B Shields
  • Xiang Gao
  • Melissa J Walker
  • Emelie C Risberg
  • Jinhui Chen
  • Naikui Liu
  • Jianguo Hu
  • Ying Li
  • Yan xia Wang
  • Pei Hua Lu
  • Sai Li Fu
  • He zuo Lu
  • Xiao Fei Wang

Detail Information

Publications9

  1. pmc Chondroitin sulfate proteoglycans regulate the growth, differentiation and migration of multipotent neural precursor cells through the integrin signaling pathway
    Wen Li Gu
    Department of Neurobiology, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, PR China
    BMC Neurosci 10:128. 2009
    ..Chondroitin sulfate proteoglycans (CSPGs) are prominent components of the extracellular matrix (ECM) in the central nervous system (CNS) and are assumed to play important roles in controlling neuronal differentiation and development...
  2. pmc Transplantation-mediated strategies to promote axonal regeneration following spinal cord injury
    Xiao Ming Xu
    Spinal Cord and Brain Injury Research Group, Stark Neurosciences Research Institute, Indiana University School of Medicine, Indianapolis, IN 46202, United States
    Respir Physiol Neurobiol 169:171-82. 2009
    ..Combinatorial approaches and clinical research are also reviewed...
  3. pmc A novel growth-promoting pathway formed by GDNF-overexpressing Schwann cells promotes propriospinal axonal regeneration, synapse formation, and partial recovery of function after spinal cord injury
    Ling Xiao Deng
    Spinal Cord and Brain Injury Research Group, Stark Neurosciences Research Institute, and Department of Neurological Surgery, Goodman and Campbell Brain and Spine, Indiana University School of Medicine, Indianapolis, Indiana 46202, USA
    J Neurosci 33:5655-67. 2013
    ..Within the distal host spinal cord, regenerated DPSN axons formed synapses with host neurons leading to the restoration of action potentials and partial recovery of function...
  4. pmc GDNF modifies reactive astrogliosis allowing robust axonal regeneration through Schwann cell-seeded guidance channels after spinal cord injury
    Ling Xiao Deng
    Spinal Cord and Brain Injury Research Group, Stark Neurosciences Research Institute, Indiana University School of Medicine, Indianapolis, IN 46202, USA
    Exp Neurol 229:238-50. 2011
    ..Thus, our study demonstrates a novel role of GDNF in modifying spinal cord injury (SCI)-induced astrogliosis resulting in robust axonal regeneration in adult rats...
  5. doi request reprint A bilateral head injury that shows graded brain damage and behavioral deficits in adultmice
    Nai Kui Liu
    Spinal Cord and Brain Injury Research Group, Stark Neurosciences Research Institute, Department of Neurological Surgery and Goodman Campbell Brain and Spine, Indiana University School of Medicine, Indianapolis, IN 46202, USA
    Brain Res 1499:121-8. 2013
    ..These findings collectively suggest that the current model may offer a sensitive, reliable and clinically-relevant model for assessments of therapeutic strategies forTBI...
  6. pmc Systemic bisperoxovanadium activates Akt/mTOR, reduces autophagy, and enhances recovery following cervical spinal cord injury
    Chandler L Walker
    Department of Anatomy and Cell Biology, Stark Neurosciences Research Institute, Indiana University School of Medicine, Indianapolis, Indiana, United States of America
    PLoS ONE 7:e30012. 2012
    ..Overall, this study demonstrates the efficacy of a clinically applicable pharmacological therapy for rapid initiation of neuroprotection post-spinal cord injury, and sheds light on the signaling involved in its action...
  7. pmc Preferential and bidirectional labeling of the rubrospinal tract with adenovirus-GFP for monitoring normal and injured axons
    Xiaofei Wang
    Spinal Cord and Brain Injury Research Group, Stark Neurosciences Research Institute, and Department of Neurological Surgery, Indiana University School of Medicine, Indianapolis, Indiana 46202, USA
    J Neurotrauma 28:635-47. 2011
    ..Thus Adv-GFP could be used as a novel tool for monitoring and evaluating strategies designed to maximize RST axonal regeneration and remodeling following SCI...
  8. pmc Altered microRNA expression following traumatic spinal cord injury
    Nai Kui Liu
    Spinal Cord and Brain Injury Research Group, Stark Neurosciences Research Institute and Department of Neurological Surgery, Indiana University School of Medicine, 950 W Walnut St, R 2 Building, Room 402, Indianapolis, IN 46202, USA
    Exp Neurol 219:424-9. 2009
    ..These findings suggest that abnormal expression of miRNAs may contribute to the pathogenesis of SCI and are potential targets for therapeutic interventions following SCI...
  9. doi request reprint Phospholipase A2 and its molecular mechanism after spinal cord injury
    Nai Kui Liu
    Spinal Cord and Brain Injury Research Group, Stark Neurosciences Research Institute, Indiana University School of Medicine, 950 W Walnut St, R 2 Building, Room 402, Indianapolis, IN 46202, USA
    Mol Neurobiol 41:197-205. 2010
    ..This review outlines the current knowledge of the PLA(2) in the spinal cord with an emphasis being placed on the possible roles of PLA(2) in mediating the secondary SCI...

Research Grants11

  1. SCHWANN CELLS, NEUROTROPHINS AND SPINAL CORD REGROWTH
    Xiao Ming Xu; Fiscal Year: 2001
    ..Taken together the specific aims of this model could be described as one with a most comprehensive attempt to maximize regeneration into the host cord tissue caudal to a Schwann cell bridged lesion. ..
  2. PKC inhibition-mediated spinal cord regeneration
    Xiao Ming Xu; Fiscal Year: 2009
    ....
  3. Role of phospholipase A2 in spinal cord secondary injury
    Xiao Ming Xu; Fiscal Year: 2009
    ..We hope that, by completion of this application, we will identify a novel target for therapeutic intervention aimed at promoting greater anatomical and functional recoveries after SCI. ..
  4. PKC inhibition-mediated spinal cord regeneration
    Xiao Ming Xu; Fiscal Year: 2006
    ....
  5. SCHWANN CELLS, NEUROTROPHINS AND SPINAL CORD REGROWTH
    Xiao Ming Xu; Fiscal Year: 2005
    ..abstract_text> ..
  6. Role of phospholipase A2 in spinal cord secondary injury
    Xiao Ming Xu; Fiscal Year: 2010
    ..We hope that, by completion of this application, we will identify a novel target for therapeutic intervention aimed at promoting greater anatomical and functional recoveries after SCI. ..