David T Wong

Summary

Affiliation: Indiana University
Country: USA

Publications

  1. ncbi request reprint Case history: the discovery of fluoxetine hydrochloride (Prozac)
    David T Wong
    Department of Psychiatry, Indiana University School of Medicine, Indianapolis 46202, USA
    Nat Rev Drug Discov 4:764-74. 2005
  2. ncbi request reprint Influence of fluoxetine on the ability of bupropion to modulate extracellular dopamine and norepinephrine concentrations in three mesocorticolimbic areas of rats
    Simon Xi Ming Li
    Neuroscience Research, Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, IN 46285, USA
    Neuropharmacology 42:181-90. 2002
  3. ncbi request reprint Fluoxetine, but not other selective serotonin uptake inhibitors, increases norepinephrine and dopamine extracellular levels in prefrontal cortex
    Frank P Bymaster
    Neuroscience Research Division, Lilly Research Laboratories, Lilly Corporate Center, Indianapolis, IN 46285 0510, USA
    Psychopharmacology (Berl) 160:353-61. 2002
  4. ncbi request reprint Implications of salivary proteomics in drug discovery and development: a focus on cancer drug discovery
    Shen Hu
    UCLA School of Dentistry and Dental Research Institute, UCLA School of Medicine, Los Angeles, CA 90095, USA
    Drug Discov Today 12:911-6. 2007

Collaborators

  • Shen Hu
  • Kenneth W Perry
  • Frank P Bymaster
  • Simon Xi Ming Li
  • David Ann
  • Yun Yen
  • Janice Shaw
  • Eyassu Chernet
  • Lee Phebus
  • Wei Zhang
  • Petra A Carter

Detail Information

Publications5

  1. ncbi request reprint Case history: the discovery of fluoxetine hydrochloride (Prozac)
    David T Wong
    Department of Psychiatry, Indiana University School of Medicine, Indianapolis 46202, USA
    Nat Rev Drug Discov 4:764-74. 2005
    ..Here, we summarize this research and discuss the many challenges that we encountered during the development of fluoxetine hydrochloride, which has now been widely acknowledged as a breakthrough drug for depression...
  2. ncbi request reprint Influence of fluoxetine on the ability of bupropion to modulate extracellular dopamine and norepinephrine concentrations in three mesocorticolimbic areas of rats
    Simon Xi Ming Li
    Neuroscience Research, Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, IN 46285, USA
    Neuropharmacology 42:181-90. 2002
    ..Furthermore, fluoxetine can potentiate the bupropion-induced DA and NE increases, which may produce more effective and rapid antidepressant actions...
  3. ncbi request reprint Fluoxetine, but not other selective serotonin uptake inhibitors, increases norepinephrine and dopamine extracellular levels in prefrontal cortex
    Frank P Bymaster
    Neuroscience Research Division, Lilly Research Laboratories, Lilly Corporate Center, Indianapolis, IN 46285 0510, USA
    Psychopharmacology (Berl) 160:353-61. 2002
    ..The effect of other SSRIs on monoamine concentrations in prefrontal cortex has not been thoroughly studied...
  4. ncbi request reprint Implications of salivary proteomics in drug discovery and development: a focus on cancer drug discovery
    Shen Hu
    UCLA School of Dentistry and Dental Research Institute, UCLA School of Medicine, Los Angeles, CA 90095, USA
    Drug Discov Today 12:911-6. 2007
    ..Potential applications of saliva proteomics in anticancer drug discovery and development will also be discussed...