C L Wellman

Summary

Affiliation: Indiana University
Country: USA

Publications

  1. pmc Convergent effects of mouse Pet-1 deletion and human PET-1 variation on amygdala fear and threat processing
    Cara L Wellman
    Department of Psychological and Brain Sciences, Center for the Integrative Study of Animal Behavior, Indiana University, Bloomington, IN, USA Electronic address
    Exp Neurol 250:260-9. 2013
  2. pmc Morphological correlates of injury-induced reorganization in primate somatosensory cortex
    James D Churchill
    Department of Psychology, Saint Louis University, St Louis, Missouri 63103, USA
    BMC Neurosci 5:43. 2004
  3. ncbi request reprint Differential effects of nucleus basalis lesions in young adult and aging rats
    C L Wellman
    Department of Psychology, Indiana University, Bloomington 47405, USA
    Neurobiol Aging 20:381-93. 1999
  4. ncbi request reprint Dendritic reorganization in pyramidal neurons in medial prefrontal cortex after chronic corticosterone administration
    C L Wellman
    Department of Psychology and Program in Neural Science, Indiana University, 1101 E 10th Street, Bloomington, IN 47405, USA
    J Neurobiol 49:245-53. 2001
  5. doi request reprint Neonatal maternal separation alters the development of glucocorticoid receptor expression in the interpositus nucleus of the cerebellum
    A A Wilber
    Department of Psychological and Brain Sciences, and Program in Neuroscience, Indiana University, Bloomington, IN 47405, United States
    Int J Dev Neurosci 27:649-54. 2009
  6. pmc Chronic stress alters neural activity in medial prefrontal cortex during retrieval of extinction
    A A Wilber
    Department of Psychological and Brain Sciences and Program in Neuroscience, 1101 East 10th Street, Indiana University, Bloomington, IN 47405, USA
    Neuroscience 174:115-31. 2011
  7. pmc Chronic stress effects on dendritic morphology in medial prefrontal cortex: sex differences and estrogen dependence
    J E Garrett
    Department of Psychological and Brain Sciences and Program in Neuroscience, 1101 East 10th Street, Indiana University, Bloomington, IN 47405, USA
    Neuroscience 162:195-207. 2009
  8. ncbi request reprint Impaired stress-coping and fear extinction and abnormal corticolimbic morphology in serotonin transporter knock-out mice
    C L Wellman
    Department of Psychological and Brain Sciences, Indiana University, Bloomington, Indiana 47405, USA
    J Neurosci 27:684-91. 2007
  9. pmc Electrophysiological and structural alterations in striatum associated with behavioral sensitization to (±)3,4-methylenedioxymethamphetamine (Ecstasy) in rats: role of drug context
    K T Ball
    Department of Psychology, Bloomsburg University of Pennsylvania, 400 East Second Street, Bloomsburg, PA 17815 1303, USA
    Neuroscience 171:794-811. 2010
  10. pmc Receptor autoradiographic correlates of deafferentation-induced reorganization in adult primate somatosensory cortex
    Preston E Garraghty
    Department of Psychological and Brain Sciences, Indiana University, Bloomington, Indiana 47405 7007, USA
    J Comp Neurol 497:636-45. 2006

Research Grants

Collaborators

Detail Information

Publications20

  1. pmc Convergent effects of mouse Pet-1 deletion and human PET-1 variation on amygdala fear and threat processing
    Cara L Wellman
    Department of Psychological and Brain Sciences, Center for the Integrative Study of Animal Behavior, Indiana University, Bloomington, IN, USA Electronic address
    Exp Neurol 250:260-9. 2013
    ....
  2. pmc Morphological correlates of injury-induced reorganization in primate somatosensory cortex
    James D Churchill
    Department of Psychology, Saint Louis University, St Louis, Missouri 63103, USA
    BMC Neurosci 5:43. 2004
    ..In this study, we used Golgi impregnation and light microscopy to assess dendritic morphology following denervation of the glabrous hand surface in adult primates...
  3. ncbi request reprint Differential effects of nucleus basalis lesions in young adult and aging rats
    C L Wellman
    Department of Psychology, Indiana University, Bloomington 47405, USA
    Neurobiol Aging 20:381-93. 1999
    ..Lesions increased GABA, and AMPA receptor binding in young adult rats only. These lesion-induced changes may reflect a compensatory response that is lost with advancing age...
  4. ncbi request reprint Dendritic reorganization in pyramidal neurons in medial prefrontal cortex after chronic corticosterone administration
    C L Wellman
    Department of Psychology and Program in Neural Science, Indiana University, 1101 E 10th Street, Bloomington, IN 47405, USA
    J Neurobiol 49:245-53. 2001
    ..Thus, chronic glucocorticoid administration dramatically reorganized apical arbors in medial prefrontal cortex. This reorganization likely reflects functional changes and may contribute to stress-induced changes in cognition...
  5. doi request reprint Neonatal maternal separation alters the development of glucocorticoid receptor expression in the interpositus nucleus of the cerebellum
    A A Wilber
    Department of Psychological and Brain Sciences, and Program in Neuroscience, Indiana University, Bloomington, IN 47405, United States
    Int J Dev Neurosci 27:649-54. 2009
    ..Thus, maternal separation may impair learning and memory in adult males by altering normal developmental changes in glucocorticoid receptor expression...
  6. pmc Chronic stress alters neural activity in medial prefrontal cortex during retrieval of extinction
    A A Wilber
    Department of Psychological and Brain Sciences and Program in Neuroscience, 1101 East 10th Street, Indiana University, Bloomington, IN 47405, USA
    Neuroscience 174:115-31. 2011
    ..Thus, the stress-induced alteration of neuronal activity in infralimbic cortex may be responsible for the stress-induced deficit in retrieval of extinction...
  7. pmc Chronic stress effects on dendritic morphology in medial prefrontal cortex: sex differences and estrogen dependence
    J E Garrett
    Department of Psychological and Brain Sciences and Program in Neuroscience, 1101 East 10th Street, Indiana University, Bloomington, IN 47405, USA
    Neuroscience 162:195-207. 2009
    ..Thus, the stress-induced increase in apical dendritic material in females is estradiol-dependent...
  8. ncbi request reprint Impaired stress-coping and fear extinction and abnormal corticolimbic morphology in serotonin transporter knock-out mice
    C L Wellman
    Department of Psychological and Brain Sciences, Indiana University, Bloomington, Indiana 47405, USA
    J Neurosci 27:684-91. 2007
    ..These data provide insight into the behavioral sequelae of loss of 5-HTT gene function and identify potential neural substrates underlying these phenotypes...
  9. pmc Electrophysiological and structural alterations in striatum associated with behavioral sensitization to (±)3,4-methylenedioxymethamphetamine (Ecstasy) in rats: role of drug context
    K T Ball
    Department of Psychology, Bloomsburg University of Pennsylvania, 400 East Second Street, Bloomsburg, PA 17815 1303, USA
    Neuroscience 171:794-811. 2010
    ....
  10. pmc Receptor autoradiographic correlates of deafferentation-induced reorganization in adult primate somatosensory cortex
    Preston E Garraghty
    Department of Psychological and Brain Sciences, Indiana University, Bloomington, Indiana 47405 7007, USA
    J Comp Neurol 497:636-45. 2006
    ..These findings are consistent with our previous suggestion that the second stage of reorganization proceeds via mechanisms comparable to those revealed to account for NMDA-dependent long-term potentiation in the hippocampus...
  11. ncbi request reprint Effect of N-methyl-d-aspartate receptor blockade on plasticity of frontal cortex after cholinergic deafferentation in rat
    J E Garrett
    Department of Psychological and Brain Sciences, Indiana University, Bloomington, IN 47405, USA
    Neuroscience 140:57-66. 2006
    ..Thus, N-methyl-d-aspartate receptor blockade prevented both GluR1 and spine density upregulation following cholinergic deafferentation, suggesting that these effects are N-methyl-d-aspartate receptor-mediated...
  12. ncbi request reprint Neonatal maternal separation-induced changes in glucocorticoid receptor expression in posterior interpositus interneurons but not projection neurons predict deficits in adult eyeblink conditioning
    A A Wilber
    Department of Psychological and Brain Sciences and Program in Neuroscience, Indiana University, 1101 East 10th Street, Bloomington, IN 47405, United States
    Neurosci Lett 460:214-8. 2009
    ..Thus, neonatal maternal separation may alter interneuronal modulation of interpositus output neurons, producing deficits in adult eyeblink conditioning...
  13. pmc Sensitizing regimens of (+/-)3, 4-methylenedioxymethamphetamine (ecstasy) elicit enduring and differential structural alterations in the brain motive circuit of the rat
    K T Ball
    Department of Psychology, Bloomsburg University of Pennsylvania, 400 East Second Street, Bloomsburg, PA 17815 1301, USA
    Neuroscience 160:264-74. 2009
    ..The differential plasticity in cortical subregions, moreover, suggests that drug-induced structural changes are not homogeneous and may be specific to the circuitry underlying long-term changes in drug-seeking and drug-taking behavior...
  14. ncbi request reprint Differential environmental exposure alters NMDA but not AMPA receptor subunit expression in nucleus accumbens core and shell
    David A Wood
    Program in Neural Science, Department of Psychology, Indiana University, 1101 E Tenth Street, Bloomington, IN 47405 7007, USA
    Brain Res 1042:176-83. 2005
    ..Increased expression of the NR1 subunit in the NAcc of SI rats may augment impulsivity and reward-seeking behavior relative to EE rats...
  15. ncbi request reprint Acute reductions in GABAA receptor binding in layer IV of adult primate somatosensory cortex after peripheral nerve injury
    C L Wellman
    Department of Psychology, Program in Neural Science, Indiana University, Bloomington, IN 47405, USA
    Brain Res 954:68-72. 2002
    ..Here we report reductions in GABA(A) receptor binding in layer IV of primate somatosensory cortex deprived of its normal activating inputs for 2-5 h by peripheral nerve transection...
  16. doi request reprint Brief neonatal maternal separation alters extinction of conditioned fear and corticolimbic glucocorticoid and NMDA receptor expression in adult rats
    Aaron A Wilber
    Department of Psychological and Brain Sciences, Indiana University, Bloomington, Indiana, USA
    Dev Neurobiol 69:73-87. 2009
    ..Thus, brief maternal separation impaired extinction recall and altered GR and NR1 expression in its neural substrate in adults...
  17. ncbi request reprint NMDA receptor binding declines differentially in three spinal motor nuclei during postnatal development
    Tom Verhovshek
    Program in Neural Science, Department of Psychology, Indiana University, Bloomington, IN 47405, USA
    Neurosci Lett 384:122-6. 2005
    ....
  18. ncbi request reprint Aging and cholinergic deafferentation alter GluR1 expression in rat frontal cortex
    Irene Kim
    Department of Psychology, Indiana University, Bloomington, IN 47405, USA
    Neurobiol Aging 26:1073-81. 2005
    ..This age-related difference in lesion-induced expression of AMPA receptor subunit protein could underlie the age-related differences in dendritic plasticity after NBM lesions...
  19. ncbi request reprint Mild, short-term stress alters dendritic morphology in rat medial prefrontal cortex
    Sarah M Brown
    Department of Psychology, Indiana University, Bloomington, IN 47405, USA
    Cereb Cortex 15:1714-22. 2005
    ..Thus, the stress-induced dendritic changes in medial prefrontal cortex occur rapidly, and in response to a mild stressor...
  20. ncbi request reprint Differential effects of cholinergic lesions on dendritic spines in frontal cortex of young adult and aging rats
    Kelley M Harmon
    Department of Psychology, Indiana University, Bloomington, IN 47405, USA
    Brain Res 992:60-8. 2003
    ..Thus, the upregulation of dendritic spines may be a compensatory response to deafferentation, which is lost with advancing age...

Research Grants1

  1. Chronic Glucocorticoid Effects in Prefrontal Cortex
    CARA WELLMAN; Fiscal Year: 2005
    ..Finally, to determine whether stress alters a prefrontally mediated behavior, I will assess the effect of chronic restraint stress on extinction of fear conditioning ..