Research Topics
Species | M H WeinbergerSummaryAffiliation: Indiana University Country: USA Publications
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Detail Information
Publications
Effects of eplerenone versus losartan in patients with low-renin hypertensionMyron H Weinberger
Hypertension Research Center, Indiana University School of Medicine, Indianapolis, IN 46202 5111, USA
Am Heart J 150:426-33. 2005..Agents that block aldosterone at its receptor sites, therefore, should have significant clinical benefit in patients with low-renin hypertension...
Sodium and blood pressure 2003Myron H Weinberger
Department of Medicine, Indiana University Medical Center, Indianapolis, Indiana 46202, USA
Curr Opin Cardiol 19:353-6. 2004..In view of the ongoing controversy about the importance of dietary sodium intake in blood pressure control, consideration of the most recent findings in this area is useful...
The use of selective aldosterone antagonistsMyron H Weinberger
Indiana University Medical Center, 541 Clinical Drive, Room 423, Indianapolis, IN 46202, USA
Curr Hypertens Rep 6:342-5. 2004..The major findings with this new agent are presented herein...
Eplerenone: a new selective aldosterone receptor antagonistMyron H Weinberger
Indiana University School of Medicine, Indianapolis, Indiana 46202, USA
Drugs Today (Barc) 40:481-5. 2004..This agent appears to be a promising and effective new addition for the treatment of hypertension and heart failure with few of the side-effects that have plagued earlier drugs of this class...
More on the sodium sagaMyron H Weinberger
Indiana University School of Medicine, 541 Clinical Building, Room 423, Indianapolis, IN 46202, USA
Hypertension 44:609-11. 2004
The use of aldosterone receptor blockers in the treatment of hypertensionMyron H Weinberger
Indiana University School of Medicine, 541 Clinical Drive, Room 423, Indianapolis, IN 46202, USA
J Clin Hypertens (Greenwich) 6:632-5. 2004..This review will highlight the major findings from these studies...
Is salt sensitivity of blood pressure linked to the cardiometabolic syndrome?Myron H Weinberger
Department of Medicine Hypertension, Indiana University School of Medicine, Indianapolis, IN 46202, USA
J Cardiometab Syndr 1:217-9. 2006
Comprehensive suppression of the renin-angiotensin-aldosterone system in chronic kidney disease: covering all of the basesM H Weinberger
Department of Medicine, Indiana University Medical Center, Indianapolis, Indiana 46202, USA
Kidney Int 70:2051-3. 2006..Adding aldosterone receptor blockers to these other agents may further halt the progression of CKD...
Is primary aldosteronism a benign disorder? Old evidence reconfirmedMyron H Weinberger
Hypertension Research Center, Indiana University School of Medicine, Indianapolis, IN 46202, USA
Am J Hypertens 19:628. 2006
Pathogenesis of salt sensitivity of blood pressureMyron H Weinberger
Indiana University Medical Center, 541 Clinical Drive, Room 423, Indianapolis, IN 46202, USA
Curr Hypertens Rep 8:166-70. 2006....
Eplerenone, a selective aldosterone blocker, in mild-to-moderate hypertensionMyron H Weinberger
Indiana University School of Medicine, Hypertension Research Center, Indianapolis 46202 5111, USA
Am J Hypertens 15:709-16. 2002..Eplerenone, a selective aldosterone blocker (SAB) that is highly specific for the aldosterone receptor, has the potential to be efficacious in the treatment of hypertension...
The influence of blood pressure and carbohydrate tolerance on vascular compliance in humansMyron H Weinberger
Department of Medicine, Indiana University School of Medicine, Indianapolis, USA
Am J Hypertens 15:678-82. 2002..These findings have important implications for the preclinical detection and potential prevention of hypertension, diabetes, and associated vascular disease...
Salt sensitivity is associated with an increased mortality in both normal and hypertensive humansMyron H Weinberger
Department of Medicine, Indiana University School of Medicine, Indianapolis 46202, USA
J Clin Hypertens (Greenwich) 4:274-6. 2002..Only initially normotensive, salt-resistant individuals had improved survival. Studies are continuing in order to elucidate the mechanisms by which salt sensitivity, even in normotensive subjects, may lead to reduced survival...
Effects of age, race, gender, blood pressure, and estrogen on arterial complianceMyron H Weinberger
Department of Medicine, Hypertension Research Center, Indiana University School of Medicine, Indianapolis, USA
Am J Hypertens 15:358-63. 2002..Although a variety of factors have been shown to influence vascular compliance in humans, few studies have been large enough to adequately assess the effects of age, race, gender, blood pressure (BP), and estrogen therapy...
Salt sensitivity, pulse pressure, and death in normal and hypertensive humansM H Weinberger
Indiana University School of Medicine, The Regenstrief Institute for Health Care, Roudebush Veteran s Administration Medical Center, Indianapolis, Indiana, USA
Hypertension 37:429-32. 2001..001). These observations provide unique evidence of a relationship between salt sensitivity and mortality that is independent of elevated blood pressure...
Salt and blood pressureM H Weinberger
Hypertension Research Center, Indianapolis, Indiana 46202 5111, USA
Curr Opin Cardiol 15:254-7. 2000..New observations related to the demographics, physiology, and mechanisms for these varied responses are also presented...
Achieving blood pressure goal: initial therapy with valsartan/hydrochlorothiazide combination compared with monotherapyM H Weinberger
Department of Medicine, Hypertension Research Center, Indiana University School of Medicine, Indianapolis, IN 46202, USA
J Hum Hypertens 24:823-30. 2010..These results support the use of Val/HCTZ combination as initial therapy in hypertensive patients unlikely to achieve BP control with a single agent...
Comparative efficacy and safety of combination aliskiren/amlodipine and amlodipine monotherapy in African Americans with stage 2 hypertension and obesity or metabolic syndromeMyron H Weinberger
Indiana University Medical Center, Indianapolis, IN, USA
J Am Soc Hypertens 5:489-97. 2011..4 mm Hg vs. -28.5 mm Hg; P < .001). Both treatments were well tolerated. Aliskiren/amlodipine 300/10 mg is more effective than amlodipine 10 mg in African Americans with stage 2 hypertension and obesity or MetS...
The blood pressure effects of calcium supplementation in humans of known sodium responsivenessM H Weinberger
Hypertension Research Center, Indiana University School of Medicine, Indianapolis
Am J Hypertens 6:799-805. 1993..abstract truncated at 250 words)..
Salt sensitivity and the blood pressure response to verapamilM H Weinberger
Hypertension Research Center, Indiana University School of Medicine, Indianapolis 46202-5111
Am J Hypertens 7:515-9. 1994..In this study verapamil lowered blood pressure in all subjects. We conclude that calcium channel blockade reduces blood pressure in essential hypertensive subjects during a normal sodium intake, independent of salt-sensitivity status...
A comparison of two tests for the assessment of blood pressure responses to sodiumM H Weinberger
Department of Medicine, Indiana University School of Medicine, Indianapolis 46202-5111
Am J Hypertens 6:179-84. 1993..These findings demonstrate the congruity of two different approaches for the assessment of salt responsivity of blood pressure in humans.(ABSTRACT TRUNCATED AT 250 WORDS)..
Influence of race and dietary salt on the antihypertensive efficacy of an angiotensin-converting enzyme inhibitor or a calcium channel antagonist in salt-sensitive hypertensivesM R Weir
Department of Medicine, University of Maryland School of Medicine, Baltimore, USA
Hypertension 31:1088-96. 1998..These data demonstrate that controlling for salt sensitivity diminishes race-related differences in antihypertensive activity...
Association between the CYP3A5 genotype and blood pressureHerbert Ho
Division of Clinical Pharmacology, Department of Medicine, Indiana University School of Medicine, 1001 W Tenth St, WD Myers Room W7123, Indianapolis, IN 46202, USA
Hypertension 45:294-8. 2005..We conclude that although untreated blood pressure may be higher in blacks with the CYP3A5*3/*3 genotype, the CYP3A5*1 allele may be associated with hypertension that is more refractory to treatment in this ethnic group...
Salt sensitivity as a predictor of hypertensionM H Weinberger
Hypertension Research Center, Indiana University School of Medicine, Indianapolis 46202-5111
Am J Hypertens 4:615S-616S. 1991..A variety of associated markers of salt sensitivity has been described. Recent studies also link calcium and salt sensitivity of blood pressure...
Hypertension management: differing points of view. Should we routinely measure renin levels to diagnose and treat patients with hypertension? The argument againstMyron H Weinberger
Hypertension Research Center, Indiana University Medical Center, Indianapolis, IN, USA
J Clin Hypertens (Greenwich) 7:36-7; quiz 38-9. 2005
Effects of oral calcium, potassium, digoxin, and nifedipine on natriuresis in normal humansF C Luft
Department of Medicine, Indiana University School of Medicine, Indianapolis
Am J Hypertens 2:14-9. 1989..Nifedipine may also uncouple renin from aldosterone. Oral calcium supplementation and sodium-potassium dependent ATPase inhibition did not facilitate natriuresis...
John Arthur Luetscher, Jr (1903-2005)Myron H Weinberger
Department of Medicine, Indiana University Medical Center, Indianapolis, IN, USA
Hypertension 47:627-8. 2006
Estrogens, salt, blood pressure, and cardiovascular disease in women: how do we interpret the data?Myron H Weinberger
Hypertension 47:1049-50. 2006
Salt restriction in the treatment of isolated systolic and combined hypertension: is that enough?Myron H Weinberger
Hypertension 46:31-2. 2005
The cold pressor test: a new predictor of future hypertension?Myron H Weinberger
Arch Intern Med 168:1732. 2008
Are children doomed by what they eat and drink?Myron H Weinberger
Hypertension 51:615-6. 2008
Comparative efficacy and safety of aliskiren, an oral direct renin inhibitor, and ramipril in hypertension: a 6-month, randomized, double-blind trialKarl Andersen
Department of Medicine, Division of Cardiology, Landspitali University Hospital, Reykjavik, Iceland
J Hypertens 26:589-99. 2008....
Ethnic differences in urine concentration: possible relationship to blood pressureLise Bankir
INSERM Unité 652, 17 Rue du Fer a Moulin, 75005 Paris, France
Clin J Am Soc Nephrol 2:304-12. 2007..If these results are confirmed in further studies, then vasopressin V2 receptor antagonists might offer a novel antihypertensive strategy, especially in the black population...
Long renal arteries: too much of a good thing?Myron H Weinberger
Hypertension 46:269-70. 2005
More novel effects of diet on blood pressure and lipidsMyron H Weinberger
JAMA 294:2497-8. 2005
