Thomas M Ulbright

Summary

Affiliation: Indiana University
Country: USA

Publications

  1. ncbi request reprint Primary mucinous tumors of the testis and paratestis: a report of nine cases
    Thomas M Ulbright
    Department of Pathology, Indiana University School of Medicine, Indianapolis, 46202 5280, USA
    Am J Surg Pathol 27:1221-8. 2003
  2. doi request reprint Primitive neuroectodermal tumors in patients with testicular germ cell tumors usually resemble pediatric-type central nervous system embryonal neoplasms and lack chromosome 22 rearrangements
    Thomas M Ulbright
    Department of Pathology, Indiana University School of Medicine, Indianapolis, IN, USA
    Mod Pathol 23:972-80. 2010
  3. ncbi request reprint Seminoma with tubular, microcystic, and related patterns: a study of 28 cases of unusual morphologic variants that often cause confusion with yolk sac tumor
    Thomas M Ulbright
    Department of Pathology, Indiana University School of Medicine, Indianapolis, IN 46202 5280, USA
    Am J Surg Pathol 29:500-5. 2005
  4. ncbi request reprint Intratubular large cell hyalinizing sertoli cell neoplasia of the testis: a report of 8 cases of a distinctive lesion of the Peutz-Jeghers syndrome
    Thomas M Ulbright
    Department of Pathology, Indiana University School of Medicine, Indianapolis, IN, USA
    Am J Surg Pathol 31:827-35. 2007
  5. doi request reprint Metastatic carcinoma to the testis: a clinicopathologic analysis of 26 nonincidental cases with emphasis on deceptive features
    Thomas M Ulbright
    Department of Pathology, Indiana University School of Medicine, Indianapolis, IN, USA
    Am J Surg Pathol 32:1683-93. 2008
  6. doi request reprint Seminoma with conspicuous signet ring cells: a rare, previously uncharacterized morphologic variant
    Thomas M Ulbright
    Department of Pathology, Indiana University School of Medicine, Indianapolis, IN, USA
    Am J Surg Pathol 32:1175-81. 2008
  7. ncbi request reprint Leydig cell tumors of the testis with unusual features: adipose differentiation, calcification with ossification, and spindle-shaped tumor cells
    Thomas M Ulbright
    Department of Pathology, Indiana University School of Medicine, Indianapolis 46202, USA
    Am J Surg Pathol 26:1424-33. 2002
  8. ncbi request reprint Cystic trophoblastic tumor: a nonaggressive lesion in postchemotherapy resections of patients with testicular germ cell tumors
    Thomas M Ulbright
    Department of Pathology and Laboratory Medicine, Indiana University School of Medicine, Indianapolis, IN, USA
    Am J Surg Pathol 28:1212-6. 2004
  9. ncbi request reprint The most common, clinically significant misdiagnoses in testicular tumor pathology, and how to avoid them
    Thomas M Ulbright
    Department of Pathology, Indiana University School of Medicine, Clarian Pathology Laboratory, 350 W 11th Street, Indianapolis, IN 46202, USA
    Adv Anat Pathol 15:18-27. 2008
  10. doi request reprint Molecular genetic evidence supporting the origin of somatic-type malignancy and teratoma from the same progenitor cell
    Jennifer B Kum
    Department of Pathology and Laboratory Medicine, Indiana University School of Medicine, Indianapolis, IN 46202, USA
    Am J Surg Pathol 36:1849-56. 2012

Detail Information

Publications77

  1. ncbi request reprint Primary mucinous tumors of the testis and paratestis: a report of nine cases
    Thomas M Ulbright
    Department of Pathology, Indiana University School of Medicine, Indianapolis, 46202 5280, USA
    Am J Surg Pathol 27:1221-8. 2003
    ..Clinical features are important to exclude metastasis, particularly in cases of carcinoma and, to a lesser extent, in tumors of borderline type...
  2. doi request reprint Primitive neuroectodermal tumors in patients with testicular germ cell tumors usually resemble pediatric-type central nervous system embryonal neoplasms and lack chromosome 22 rearrangements
    Thomas M Ulbright
    Department of Pathology, Indiana University School of Medicine, Indianapolis, IN, USA
    Mod Pathol 23:972-80. 2010
    ..Future treatment strategies should take these findings into account...
  3. ncbi request reprint Seminoma with tubular, microcystic, and related patterns: a study of 28 cases of unusual morphologic variants that often cause confusion with yolk sac tumor
    Thomas M Ulbright
    Department of Pathology, Indiana University School of Medicine, Indianapolis, IN 46202 5280, USA
    Am J Surg Pathol 29:500-5. 2005
    ..The edema and paucity of lymphocytes may suggest spermatocytic seminoma, but the varied cell types of that neoplasm are absent...
  4. ncbi request reprint Intratubular large cell hyalinizing sertoli cell neoplasia of the testis: a report of 8 cases of a distinctive lesion of the Peutz-Jeghers syndrome
    Thomas M Ulbright
    Department of Pathology, Indiana University School of Medicine, Indianapolis, IN, USA
    Am J Surg Pathol 31:827-35. 2007
    ..Orchiectomy is indicated when there is evidence of an invasive tumor and may be necessary to control hormonal manifestations...
  5. doi request reprint Metastatic carcinoma to the testis: a clinicopathologic analysis of 26 nonincidental cases with emphasis on deceptive features
    Thomas M Ulbright
    Department of Pathology, Indiana University School of Medicine, Indianapolis, IN, USA
    Am J Surg Pathol 32:1683-93. 2008
    ..Clues to the likely primary site can usually be gleaned from the pathologic findings...
  6. doi request reprint Seminoma with conspicuous signet ring cells: a rare, previously uncharacterized morphologic variant
    Thomas M Ulbright
    Department of Pathology, Indiana University School of Medicine, Indianapolis, IN, USA
    Am J Surg Pathol 32:1175-81. 2008
    ..The description of this phenomenon expands the known morphologic spectrum of the most common testicular neoplasm...
  7. ncbi request reprint Leydig cell tumors of the testis with unusual features: adipose differentiation, calcification with ossification, and spindle-shaped tumor cells
    Thomas M Ulbright
    Department of Pathology, Indiana University School of Medicine, Indianapolis 46202, USA
    Am J Surg Pathol 26:1424-33. 2002
    ....
  8. ncbi request reprint Cystic trophoblastic tumor: a nonaggressive lesion in postchemotherapy resections of patients with testicular germ cell tumors
    Thomas M Ulbright
    Department of Pathology and Laboratory Medicine, Indiana University School of Medicine, Indianapolis, IN, USA
    Am J Surg Pathol 28:1212-6. 2004
    ..We conclude that the finding of CTT in postchemotherapy resections does not warrant additional chemotherapy. Its clinical significance appears similar to that of residual teratoma...
  9. ncbi request reprint The most common, clinically significant misdiagnoses in testicular tumor pathology, and how to avoid them
    Thomas M Ulbright
    Department of Pathology, Indiana University School of Medicine, Clarian Pathology Laboratory, 350 W 11th Street, Indianapolis, IN 46202, USA
    Adv Anat Pathol 15:18-27. 2008
    ....
  10. doi request reprint Molecular genetic evidence supporting the origin of somatic-type malignancy and teratoma from the same progenitor cell
    Jennifer B Kum
    Department of Pathology and Laboratory Medicine, Indiana University School of Medicine, Indianapolis, IN 46202, USA
    Am J Surg Pathol 36:1849-56. 2012
    ....
  11. doi request reprint Clonal evidence for the progression of a testicular germ cell tumor to angiosarcoma
    Muhammad T Idrees
    Department of Pathology and Laboratory Medicine, Indiana University School of Medicine, Indianapolis, IN 46202, USA
    Hum Pathol 41:139-44. 2010
    ..The results indicated a clonal origin of the tumors, which supports that angiosarcoma, as well as the teratomas, arose from the testicular germ cell tumors...
  12. ncbi request reprint Fluorescence in situ hybridization analysis of chromosome 12p in paraffin-embedded tissue is useful for establishing germ cell origin of metastatic tumors
    Kevin M Kernek
    Department of Pathology and Laboratory Medicine, Indiana University School of Medicine, Indianapolis, IN 46202, USA
    Mod Pathol 17:1309-13. 2004
    ....
  13. ncbi request reprint OCT4 staining in testicular tumors: a sensitive and specific marker for seminoma and embryonal carcinoma
    Timothy D Jones
    Department of Pathology and Laboratory Medicine, Indiana University School of Medicine, Indianapolis, IN, USA
    Am J Surg Pathol 28:935-40. 2004
    ..OCT4 immunostaining has comparable sensitivity but greater consistency compared with CD30 in the diagnosis of embryonal carcinoma...
  14. ncbi request reprint Nephroblastoma arising in a germ cell tumor of testicular origin
    Robert E Emerson
    Department of Pathology and Laboratory Medicine, Indiana University School of Medicine, Indianapolis, IN 46202, USA
    Am J Surg Pathol 28:687-92. 2004
    ..These data support a common clonal origin for nephroblastoma and the other germ cell tumor components...
  15. ncbi request reprint Loss of 14-3-3sigma in prostate cancer and its precursors
    Liang Cheng
    Department of Pathology and Laboratory Medicine, Indiana University School of Medicine, Indianapolis, IN 46202, USA
    Clin Cancer Res 10:3064-8. 2004
    ..The role of 14-3-3sigma in prostatic carcinogenesis is uncertain...
  16. ncbi request reprint Clonal origin of metastatic testicular teratomas
    Timothy D Jones
    Department of Pathology and Laboratory Medicine, Indiana University School of Medicine, Indianapolis, Indiana 46202, USA, and Department of Pathology, Chang Gung Memorial Hospital Kaohsiung Medical Center, Kaohsiung, Taiwan
    Clin Cancer Res 12:5377-83. 2006
    ..Neither the genetic relationships among the different components in metastatic lesions nor the relationships between primary and metastatic GCT components have been elucidated...
  17. doi request reprint Testicular hemorrhage, necrosis, and vasculopathy: likely manifestations of intermittent torsion that clinically mimic a neoplasm
    Chia Sui Kao
    Department of Pathology and Laboratory Medicine, Indiana University School of Medicine, Indianapolis, IN
    Am J Surg Pathol 38:34-44. 2014
    ....
  18. ncbi request reprint OCT4: A sensitive and specific biomarker for intratubular germ cell neoplasia of the testis
    Timothy D Jones
    Department of Pathology and Laboratory Medicine, Indiana University School of Medicine, Indianapolis, Indiana, USA
    Clin Cancer Res 10:8544-7. 2004
    ..The present study aimed to establish OCT4 as a sensitive and specific maker for IGCNU, a putative precursor for adult germ cell tumors...
  19. ncbi request reprint Molecular genetic evidence supporting the neoplastic nature of the Leydig cell component of ovarian Sertoli-Leydig cell tumors
    Robert E Emerson
    Department of Pathology, Indiana University, Indianapolis, Indiana, USA
    Int J Gynecol Pathol 26:368-74. 2007
    ..Similarly, the heterologous components, when present, appear to share clonal origin with the Sertoli cell components...
  20. ncbi request reprint Molecular genetic evidence for the independent origin of multifocal papillary tumors in patients with papillary renal cell carcinomas
    Timothy D Jones
    Department of Pathology and Laboratory Medicine, Indiana University School of Medicine, Indianapolis, Indiana 46202, USA
    Clin Cancer Res 11:7226-33. 2005
    ..Molecular analysis of microsatellite and chromosome alterations and X-chromosome inactivation status in separate tumors in the same patient can be used to study the genetic relationships among the coexisting multiple tumors...
  21. pmc Identical allelic losses in mature teratoma and other histologic components of malignant mixed germ cell tumors of the testis
    Kevin M Kernek
    Departments of Pathology and Laboratory Medicine and Urology, Indiana University School of Medicine, Indianapolis, Indiana 46202, USA
    Am J Pathol 163:2477-84. 2003
    ..Our data support the common clonal origin of mature teratoma with other components of malignant mixed germ cell tumors of the testis...
  22. doi request reprint Molecular genetic evidence supporting the neoplastic nature of fibrous stroma in testicular teratoma
    Liang Cheng
    Department of Pathology and Laboratory Medicine, Indiana University School of Medicine, Indianapolis, IN 46202, USA
    Mod Pathol 25:1432-8. 2012
    ..Concordant chromosome 12p alterations between the fibrous stroma and epithelial elements provide further evidence that both epithelial and fibrous components of teratoma are derived from a common progenitor...
  23. ncbi request reprint Stroma adjacent to metastatic mature teratoma after chemotherapy for testicular germ cell tumors is derived from the same progenitor cells as the teratoma
    David W Brandli
    Department of Urology, Indiana University School of Medicine, Indianapolis, Indiana 46202, USA
    Cancer Res 63:6063-8. 2003
    ..Concordant genetic alterations observed in teratoma and stroma suggest that both are derived from the same element of the original germ cell tumor or the same progenitor cell...
  24. ncbi request reprint Anatomic distribution of periprostatic adipose tissue: a mapping study of 100 radical prostatectomy specimens
    Heng Hong
    Department of Pathology and Laboratory Medicine, Indiana University School of Medicine, Indianapolis, Indiana, USA
    Cancer 97:1639-43. 2003
    ..However, the distribution of adipose tissue along the prostatic surfaces has not been studied extensively...
  25. ncbi request reprint Down-regulation of fragile histidine triad expression in prostate carcinoma
    Rebecca L Fouts
    Department of Pathology and Laboratory Medicine, Indiana University School of Medicine, Indianapolis, Indiana, USA
    Cancer 97:1447-52. 2003
    ..Numerous studies have indicated that the FHIT gene on chromosome 3p may play an important role in human neoplasia, although very few studies have investigated the FHIT gene in prostate carcinoma...
  26. ncbi request reprint Molecular genetic alterations in the laser-capture-microdissected stroma adjacent to bladder carcinoma
    Ryan F Paterson
    Department of Urology, Indiana University School of Medicine, Indianapolis, Indianapolis 46202, USA
    Cancer 98:1830-6. 2003
    ..In addition, the pattern of X-chromosome inactivation of the stromal cells was evaluated by analyzing the DNA methylation pattern at a polymorphic site on the androgen receptor gene...
  27. doi request reprint The utility of microscopic findings and immunohistochemistry in the classification of necrotic testicular tumors: a study of 11 cases
    Jeremy S Miller
    Department of Pathology, The Johns Hopkins Hospital, Baltimore, MD, USA
    Am J Surg Pathol 33:1293-8. 2009
    ..Most totally necrotic testicular tumors can be placed into clinically important groups by assessment for coarse intratubular calcifications and staining reactions for keratin, OCT4, CD117, and CD30...
  28. ncbi request reprint Maximum tumor diameter is an independent predictor of prostate-specific antigen recurrence in prostate cancer
    Lori E Eichelberger
    Department of Pathology and Laboratory Medicine, Indiana University School of Medicine, Indianapolis, IN 46202, USA
    Mod Pathol 18:886-90. 2005
    ..13-2.56, P=0.01), controlling for risk factors, Gleason score, and surgical margin status. We conclude that maximum tumor diameter is a significant predictor of biochemical recurrence in patients with prostate cancer...
  29. ncbi request reprint Impact of the number of positive lymph nodes on disease-free survival in patients with pathological stage B1 nonseminomatous germ cell tumor
    Stephen D W Beck
    Department of Urology and Pathology, Indiana University Medical Center, Indianapolis, Indiana, USA
    J Urol 174:143-5. 2005
    ..We tested this hypothesis in patients with pathological stage B1 nonseminomatous germ cell tumor (NSGCT)...
  30. doi request reprint Differentiated rhabdomyomatous tumors after chemotherapy for metastatic testicular germ-cell tumors: a clinicopathological study of seven cases mandating separation from rhabdomyosarcoma
    Jessica A Clevenger
    Department of Pathology, Indiana University School of Medicine, Indianapolis, IN 46202, USA
    Mod Pathol 22:1361-6. 2009
    ..We believe the most likely explanation for the finding of pure rhabdomyomatous tumors in this setting, a phenomenon sometimes termed 'cytodifferentiation,' is selective persistence of differentiated tumor cells because of chemotherapy...
  31. ncbi request reprint PC cell-derived growth factor expression in prostatic intraepithelial neoplasia and prostatic adenocarcinoma
    Chong Xian Pan
    Department of Medicine, Indiana University School of Medicine, Indianapolis, Indiana 46202, USA
    Clin Cancer Res 10:1333-7. 2004
    ..It is a novel growth factor that stimulates cell proliferation, confers epithelial tumorigenesis, and promotes tumor invasion. Here we investigate the potential of PCDGF as a therapeutic target for prostate cancer...
  32. doi request reprint p16 expression is not associated with human papillomavirus in urinary bladder squamous cell carcinoma
    Riley E Alexander
    Department of Pathology and Laboratory Medicine, Indiana University School of Medicine, Indianapolis, IN 46202, USA
    Mod Pathol 25:1526-33. 2012
    ....
  33. doi request reprint Solid pattern yolk sac tumor: a morphologic and immunohistochemical study of 52 cases
    Chia Sui Kao
    Department of Pathology and Laboratory Medicine, Indiana University School of Medicine, Indianapolis, IN 46202, USA
    Am J Surg Pathol 36:360-7. 2012
    ..Common CD117 positivity in solid pattern yolk sac tumors makes it an unreliable discriminator between yolk sac tumor and seminoma...
  34. doi request reprint Cytoplasmic p63 immunohistochemistry is a useful marker for muscle differentiation: an immunohistochemical and immunoelectron microscopic study
    Sarah E Martin
    Department of Pathology and Laboratory Medicine, Indiana University School of Medicine, Indianapolis, IN, USA
    Mod Pathol 24:1320-6. 2011
    ..We conclude that p63 immunostain is a sensitive marker for skeletal muscle differentiation and highlights the cross-striations of strap cells with exceptional definition...
  35. ncbi request reprint Malignant Sertoli cell tumors of the testis: a study of 13 examples of a neoplasm frequently misinterpreted as seminoma
    John D Henley
    Departments of Pathology, Indiana University School of Medicine, Indianapolis, Indiana, USA
    Am J Surg Pathol 26:541-50. 2002
    ....
  36. ncbi request reprint Heterogeneity of Gleason grade in multifocal adenocarcinoma of the prostate
    Rebecca Arora
    Department of Pathology and Laboratory Medicine, Indiana University School of Medicine, Indianapolis, Indiana 46202, USA
    Cancer 100:2362-6. 2004
    ..The current study was undertaken to compare the Gleason grades of individual adenocarcinoma foci in a given specimen with the overall Gleason grades (primary and secondary) of that specimen...
  37. ncbi request reprint Histology in mixed germ cell tumors. Is there a favorite pairing?
    Ashraf A Mosharafa
    Department of Urology, Indiana University School of Medicine, Indianapolis, Indiana, USA
    J Urol 171:1471-3. 2004
    ..It was our impression that such associations exist. Delineating concordant histological types may provide insight into the ontogeny of testicular tumors and also have important clinical implications...
  38. ncbi request reprint Primary testicular diffuse large B-cell lymphoma belongs to the nongerminal center B-cell-like subgroup: A study of 18 cases
    Mousa A Al-Abbadi
    Department of Pathology, Wayne State University, Detroit, MI, USA
    Mod Pathol 19:1521-7. 2006
    ..We conclude that most (89%) primary testicular lymphomas of the diffuse large B-cell type belong to the nongerminal center B-cell-like subgroup and have high proliferative activity...
  39. doi request reprint Difficult differential diagnoses in testicular pathology
    Huihui Ye
    Department of Pathology, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA
    Arch Pathol Lab Med 136:435-46. 2012
    ..Pathologists must, therefore, be familiar with important diagnostic pitfalls in testicular pathology, particularly those that result in different treatments or prognoses...
  40. doi request reprint Macroscopic sertoli cell nodule: a study of 6 cases that presented as testicular masses
    Bethany D Vallangeon
    Department of Pathology and Laboratory Medicine, Indiana University School of Medicine, Clarian Pathology Laboratory, Indianapolis, IN, USA
    Am J Surg Pathol 34:1874-80. 2010
    ..We conclude that Sertoli cell nodules may present clinically as mass lesions, and that it is important to distinguish them from true neoplasms to avoid unnecessary procedures...
  41. ncbi request reprint Germ cell tumors of the gonads: a selective review emphasizing problems in differential diagnosis, newly appreciated, and controversial issues
    Thomas M Ulbright
    Department of Pathology and Laboratory Medicine, Clarian Health Partners and Indiana University School of Medicine, Indianapolis, IN 46202 5280, USA
    Mod Pathol 18:S61-79. 2005
    ....
  42. ncbi request reprint Analysis of ovarian teratomas for isochromosome 12p: evidence supporting a dual histogenetic pathway for teratomatous elements
    Christopher Poulos
    Department of Pathology, Indiana University School of Medicine, Indianapolis, IN 46202 5280, USA
    Mod Pathol 19:766-71. 2006
    ..Furthermore, the findings of i(12p) in both the teratomatous and nonteratomatous components of ovarian mixed GCTs supports that the teratoma derives from other components, similar to the situation in the testis...
  43. ncbi request reprint Sclerosing Sertoli cell tumor of the testis: a clinicopathologic study of 20 cases
    Chia Sui Kao
    Department of Pathology and Laboratory Medicine, Indiana University School of Medicine, Indianapolis, IN
    Am J Surg Pathol 38:510-7. 2014
    ..We conclude that SSCTs<2 cm with the typical features and lacking those associated with malignancy in Sertoli cell tumors, not otherwise specified, have a negligible risk of metastasis and are adequately managed by orchiectomy alone. ..
  44. doi request reprint Podoplanin, a novel marker for seminoma: A comparison study evaluating immunohistochemical expression of podoplanin and OCT3/4
    Muhammad Idrees
    Department of Pathology, Indiana University School of Medicine, Indianapolis, 46202, USA
    Ann Diagn Pathol 14:331-6. 2010
    ..The identification by podoplanin of seminoma cells lying adjacent to foci of embryonal carcinoma gives credence to the hypothesis that the latter arise from seminomas as part of a process of "differentiation."..
  45. pmc Morphological approach to tumours of the testis and paratestis
    Robert E Emerson
    Department of Pathology and Laboratory Medicine, Indiana University School of Medicine, Indianapolis, Indiana 46202, USA
    J Clin Pathol 60:866-80. 2007
    ..In some problematic cases, immunohistochemical staining may be useful to resolve these differential diagnoses...
  46. ncbi request reprint Primary testicular and paratesticular lymphoma: a retrospective clinicopathologic study of 34 cases with emphasis on differential diagnosis
    Mousa A Al-Abbadi
    Department of Pathology, Wayne State University Detroit Medical Center, Detroit, Mich, USA
    Arch Pathol Lab Med 131:1040-6. 2007
    ..Recent reports indicate the rate of primary testicular lymphomas is on the rise and misdiagnosis can still occur...
  47. pmc High-level expression of EphA2 receptor tyrosine kinase in prostatic intraepithelial neoplasia
    Guangyuan Zeng
    Departments of Pathology and Laboratory Medicine, Indiana University School of Medicine, Indianapolis, Indiana 46202, USA
    Am J Pathol 163:2271-6. 2003
    ..Moreover, the presence of high levels of EphA2 in these cells suggests opportunities for prostate cancer prevention and treatment...
  48. ncbi request reprint Large cell carcinoma of the lung mimicking a germ cell tumor: the potential value of chromosome analysis
    Syed M Ahmed
    Department of Internal Medicine, Indiana University School of Medicine, Indianapolis, IN, USA
    Lung Cancer 49:271-4. 2005
  49. ncbi request reprint Molecular evidence supporting the neoplastic nature of some epidermoid cysts of the testis
    Cheryl Younger
    Department of Pathology and Laboratory Medicine, Indiana University School of Medicine, Indianapolis 46202, USA
    Arch Pathol Lab Med 127:858-60. 2003
    ..Loss of heterozygosity of 17p13 has also been demonstrated in germ cell tumors. The incidence of LOH in epidermoid cysts, a possible special form of teratoma, has not been previously determined...
  50. ncbi request reprint Divergent pathway of intestinal metaplasia and cystitis glandularis of the urinary bladder
    Ming Tse Sung
    Department of Pathology and Laboratory Medicine, Indiana University School of Medicine, Indianapolis, IN 46202, USA
    Mod Pathol 19:1395-401. 2006
    ....
  51. doi request reprint Testicular fibrothecoma: a morphologic and immunohistochemical study of 16 cases
    Miao Zhang
    Department of Pathology, Johns Hopkins Hospital, Baltimore, MD 21231, USA
    Am J Surg Pathol 37:1208-14. 2013
    ..Their immunoprofile is variable and typically not diagnostic. Despite some worrisome histologic features, they appear uniformly benign in their behavior. ..
  52. doi request reprint Signet ring cell carcinoma of the testis: clinicopathologic and molecular evidence for germ cell tumor origin--a case report
    Sean R Williamson
    Departments of Pathology and Laboratory Medicine, Indiana University School of Medicine, Indianapolis, IN 46202, USA
    Am J Surg Pathol 36:311-5. 2012
    ..This is the first report of testicular signet ring cell carcinoma of germ cell tumor derivation...
  53. ncbi request reprint The use of immunohistochemistry in the differential diagnosis of tumors of the testis and paratestis
    Robert E Emerson
    Department of Pathology, Indiana University School of Medicine, Indianapolis, USA
    Semin Diagn Pathol 22:33-50. 2005
    ..This article reviews the application of immunohistochemical markers for a number of differential diagnostic considerations in the testis and paratestis categorized according to their light microscopic patterns...
  54. ncbi request reprint Apoptosis in spermatocytic and usual seminomas: a light microscopic and immunohistochemical study
    Elena F Bishop
    Department of Pathology, Indiana University School of Medicine, Indianapolis, IN 46202, USA
    Mod Pathol 20:1036-44. 2007
    ..The variation in apoptosis of usual seminomas merits investigation as a prognostic parameter...
  55. ncbi request reprint Predicting tumor volume in radical prostatectomy specimens from patients with prostate cancer
    Lori E Eichelberger
    Departments of Pathology and Laboratory Medicine, Indiana University School of Medicine, Indianapolis, USA
    Am J Clin Pathol 120:386-91. 2003
    ..004), Gleason score (P = .004), and pathologic stage (P < .0001). Maximum tumor diameter is a predictor of tumor volume and might be useful for the assessment of tumor volume in routinely processed prostatectomy specimens...
  56. ncbi request reprint Does retroperitoneal lymph node dissection have a curative role for patients with sex cord-stromal testicular tumors?
    Ashraf A Mosharafa
    Department of Urology, Indiana University School of Medicine, Indianapolis, Indiana 46202, USA
    Cancer 98:753-7. 2003
    ..The authors attempt to evaluate the role of retroperitoneal lymph node dissection (RPLND) in the management of patients with these malignant sex cord-stromal tumors...
  57. ncbi request reprint Fas and Fas ligand expression is elevated in prostatic intraepithelial neoplasia and prostatic adenocarcinoma
    Jiazhong Jiang
    Department of Pathology and Laboratory Medicine, Indiana University School of Medicine, Indianapolis, Indiana 46202, USA
    Cancer 95:296-300. 2002
    ..On binding to Fas ligand, a Type II transmembrane protein, the Fas/Fas ligand complex, induces apoptosis in target cells. Dysregulation of Fas and Fas ligand expression has been found in some malignant neoplasms...
  58. ncbi request reprint Testicular embryonal carcinoma: a morphologic study of 180 cases highlighting unusual and unemphasized aspects
    Chia Sui Kao
    Department of Pathology and Laboratory Medicine, Indiana University School of Medicine, Indianapolis, IN The James Homer Wright Pathology Laboratory, Massachusetts General Hospital, Harvard Medical School, Boston, MA
    Am J Surg Pathol 38:689-97. 2014
    ..The association with other more common patterns and typical cytologic features, together with simple awareness of these variant morphologies, are helpful in establishing an accurate diagnosis of EC. ..
  59. doi request reprint A case report of adrenocortical carcinosarcoma with oncocytic and primitive neuroectodermal-like features
    Chia Sui Kao
    Department of Pathology and Laboratory Medicine, Indiana University School of Medicine, Indianapolis, IN 46202, USA
    Hum Pathol 44:1947-55. 2013
    ..Adrenal carcinosarcoma is a rare highly aggressive malignancy with a wide morphologic spectrum. Recognition of variant morphology and applying correct immunohistochemical studies will aid in reaching an accurate diagnosis. ..
  60. doi request reprint Anastomosing hemangioma of the liver and gastrointestinal tract: an unusual variant histologically mimicking angiosarcoma
    Jingmei Lin
    Department of Pathology and Laboratory Medicine, Indiana University School of Medicine, Indianapolis, IN Department of Pathology, The Johns Hopkins Hospital, Baltimore, MD
    Am J Surg Pathol 37:1761-5. 2013
    ..Despite small numbers and limited follow-up information in our series, evidence to date supports that the lesion is benign. Awareness of this entity is essential to avoid overdiagnosis and unnecessary aggressive treatment...
  61. doi request reprint Evidence supporting the existence of benign teratomas of the postpubertal testis: a clinical, histopathologic, and molecular genetic analysis of 25 cases
    Chen Zhang
    Department of Pathology and Laboratory Medicine, Indiana University School of Medicine, Indiana University Health Partners, Indianapolis, IN, USA
    Am J Surg Pathol 37:827-35. 2013
    ..It is important to distinguish these teratomas from the usual ones seen in postpuberal patients because of the malignant potential of the latter...
  62. doi request reprint Does intratubular germ cell neoplasia, unclassified type exist in prepubertal, cryptorchid testes?
    Rong Fan
    Department of Pathology and Laboratory Medicine Indiana University, Indianapolis, Indiana, USA
    Fetal Pediatr Pathol 31:21-4. 2012
    ..We therefore did not find a bona fide case of IGCNU in prepubertal testes apart from an intersex disorder...
  63. ncbi request reprint Seminomas with exclusive intertubular growth: a report of 12 clinically and grossly inconspicuous tumors
    John D Henley
    Department of Pathology, Indiana University School of Medicine, Indianapolis, IN 46202 5280, USA
    Am J Surg Pathol 28:1163-8. 2004
    ..In pure form, intertubular seminoma is both clinically and pathologically inconspicuous and may be misdiagnosed as atrophy, scar, or orchitis...
  64. doi request reprint Intratubular germ cell neoplasia of the testis and its associated cancers: the use of novel biomarkers
    Robert E Emerson
    Department of Pathology and Laboratory Medicine, Indiana University School of Medicine, Indianapolis, IN, USA
    Pathology 42:344-55. 2010
    ..Suggested immunohistochemical panels are described for individual tumour types...
  65. ncbi request reprint Update on late relapse of germ cell tumor: a clinical and molecular analysis
    David W George
    Department of Medicine, and Section of Hematology Oncology, Herman B Wells Center for Pediatric Research, Indiana University Medical Center, Indianapolis, IN, USA
    J Clin Oncol 21:113-22. 2003
    ..Analysis of patients with late relapse (LR) of germ cell tumor (GCT) with reports on clinical characteristics, outcomes, and molecular and cytogenetic features...
  66. ncbi request reprint Ovarian endometrioid tumors of low malignant potential: a clinicopathologic study of 30 cases with comparison to well-differentiated endometrioid adenocarcinoma
    Lawrence M Roth
    Department of Pathology, Indiana University School of Medicine and Hospital, Indianapolis, 46202 5280, USA
    Am J Surg Pathol 27:1253-9. 2003
    ..Thus, the prognosis of ETLMP, when defined by the above criteria, is favorable and is superior to that of well-differentiated endometrioid adenocarcinoma...
  67. doi request reprint Atypical ductal hyperplasia: interobserver and intraobserver variability
    Rohit K Jain
    Department of Pathology and Laboratory Science, I U School of Medicine, Indianapolis, IN, USA
    Mod Pathol 24:917-23. 2011
    ....
  68. ncbi request reprint Gonadal teratomas: a review and speculation
    Thomas M Ulbright
    Department of Pathology, Indiana University School of Medicine, Indianapolis, Indiana 46202 5280, USA
    Adv Anat Pathol 11:10-23. 2004
    ..The teratomatous components of mixed germ cell tumors of the ovary, on the other hand, likely have a pathogenesis similar to that of postpubertal testicular teratomas...
  69. pmc Availability and quality of paraffin blocks identified in pathology archives: a multi-institutional study by the Shared Pathology Informatics Network (SPIN)
    Ashokkumar A Patel
    Department of Pathology, Center for Pathology Informatics, Benedum Oncology Informatics Center, University of Pittsburgh, Pittsburgh, PA, USA
    BMC Cancer 7:37. 2007
    ..This paper examines if tissue blocks, identified by localized computer searches at participating institutions, can be retrieved in adequate quantity and quality to support medical researchers...
  70. ncbi request reprint Cytogenetics of a pediatric unclassified sex cord-stromal tumor of the testis: a case report
    David T Yang
    Department of Pathology, University of Utah Health Sciences Center, Room A513, 50 North Medical Drive, Salt Lake City, UT 84132, USA
    Cancer Genet Cytogenet 156:80-2. 2005
    ..We describe an unclassified sex cord-stromal tumor occurring in the testis of a prepubertal male without evidence of metastasis that had a previously unreported 54,XY,+3,+7,+9,+12,+13,+18,+19,+20 karyotype...
  71. ncbi request reprint Spontaneous regression of testicular germ cell tumors: an analysis of 42 cases
    Bonnie L Balzer
    Department of Pathology, Stanford University Hospital and Clinics, Stanford, CA, USA
    Am J Surg Pathol 30:858-65. 2006
    ..In contrast, nonspecific atrophy lacks distinct scars, and scars from non-neoplastic causes lack most of the associated findings seen in our cases...
  72. ncbi request reprint Precise microdissection of human bladder carcinomas reveals divergent tumor subclones in the same tumor
    Liang Cheng
    Department of Pathology, Indiana University School of Medicine, Indianapolis, IN 46202, USA
    Cancer 94:104-10. 2002
    ..Human bladder carcinoma is thought to arise from a field change that affects the entire urothelium. Whether independently transformed urothelial cell populations exist in the same patient is uncertain...
  73. ncbi request reprint Primary choriocarcinoma of the bladder with the detection of isochromosome 12p
    Nasser H Hanna
    Department of Medicine, Indiana University School of Medicine, Indianapolis, Indiana, USA
    J Urol 167:1781. 2002
  74. ncbi request reprint Relationship among histologic, radiologic, and biochemical assessments of hepatic steatosis: a study of human liver samples
    Raj Vuppalanchi
    Department of Medicine, Indiana University School of Medicine, Indianapolis, IN 46202, USA
    J Clin Gastroenterol 41:206-10. 2007
    ..Therefore, we examined the relationship between hepatic triglyceride (TG) content and nonbiochemical assessment of steatosis in 38 human liver samples...
  75. doi request reprint Estimation of impact of American College of Radiology recommendations on CT colonography reporting for resection of high-risk adenoma findings
    Douglas K Rex
    Division of Gastroenterology, Indiana University Medical Center, Indianapolis, Indiana, USA
    Am J Gastroenterol 104:149-53. 2009
    ..The aim of the study was to determine the impact of ACR recommendations on resection of high-risk adenoma findings using an endoscopic polyp/histology database...
  76. ncbi request reprint Reply: mixed germ cell sex cord-stromal tumors of the testis and ovary
    Thomas M Ulbright
    Virchows Arch 450:131-2. 2007
  77. ncbi request reprint Carcinoid tumor of the testis
    Thomas M Ulbright
    Am J Clin Pathol 121:297; author reply 298. 2004