Larry Thibos

Summary

Affiliation: Indiana University
Country: USA

Publications

  1. ncbi Power vectors: an application of Fourier analysis to the description and statistical analysis of refractive error
    L N Thibos
    School of Optometry, Indiana University, Bloomington, USA
    Optom Vis Sci 74:367-75. 1997
  2. ncbi Unresolved issues in the prediction of subjective refraction from wavefront aberration maps
    Larry N Thibos
    Indiana University, School of Optometry, Bloomington, IN 47405, USA
    J Refract Surg 20:S533-6. 2004
  3. doi The 2012 Charles Prentice medal lecture: wavefront measurement of refractive state
    Larry N Thibos
    School of Optometry, Indiana University, Bloomington, IN 47405 3680, USA
    Optom Vis Sci 90:911-23. 2013
  4. doi Modelling the impact of spherical aberration on accommodation
    Larry N Thibos
    School of Optometry, Indiana University, Bloomington, Indiana, USA
    Ophthalmic Physiol Opt 33:482-96. 2013
  5. ncbi Where is the optimum far-point for a presbyopic eye?
    Larry N Thibos
    School of Optometry, Indiana University, Bloomington, IN 47405, USA
    J Refract Surg 24:970-5. 2008
  6. ncbi The optics of wavefront sensing
    Larry N Thibos
    School of Optometry, Indiana University, 800 E Atwater Avenue, Bloomington, IN 47405, USA
    Ophthalmol Clin North Am 17:111-7, v. 2004
  7. doi Retinal image quality for virtual eyes generated by a statistical model of ocular wavefront aberrations
    Larry N Thibos
    School of Optometry, Indiana University, Bloomington, IN 47405, USA
    Ophthalmic Physiol Opt 29:288-91. 2009
  8. ncbi Accuracy and precision of objective refraction from wavefront aberrations
    Larry N Thibos
    School of Optometry, Indiana University, Bloomington, IN, USA
    J Vis 4:329-51. 2004
  9. ncbi Design principles and limitations of wave-front guided contact lenses
    Larry N Thibos
    School of Optometry, Indiana University, Bloomington, IN 47405, USA
    Eye Contact Lens 29:S167-70; discussion S190-1, S192-4. 2003
  10. ncbi Statistical variation of aberration structure and image quality in a normal population of healthy eyes
    Larry N Thibos
    School of Optometry, Indiana University, Bloomington, Indiana 47405, USA
    J Opt Soc Am A Opt Image Sci Vis 19:2329-48. 2002

Detail Information

Publications51

  1. ncbi Power vectors: an application of Fourier analysis to the description and statistical analysis of refractive error
    L N Thibos
    School of Optometry, Indiana University, Bloomington, USA
    Optom Vis Sci 74:367-75. 1997
    ....
  2. ncbi Unresolved issues in the prediction of subjective refraction from wavefront aberration maps
    Larry N Thibos
    Indiana University, School of Optometry, Bloomington, IN 47405, USA
    J Refract Surg 20:S533-6. 2004
    ..The conclusion points to future experiments needed to resolve these uncertainties to achieve more accurate and precise methods of objective wavefront refraction...
  3. doi The 2012 Charles Prentice medal lecture: wavefront measurement of refractive state
    Larry N Thibos
    School of Optometry, Indiana University, Bloomington, IN 47405 3680, USA
    Optom Vis Sci 90:911-23. 2013
    ..The aim of this lecture is to help make advances in these areas of optometric science broadly accessible to educators, clinicians, and patients by explaining in simple terms the underlying optical concepts of wavefront aberrometry...
  4. doi Modelling the impact of spherical aberration on accommodation
    Larry N Thibos
    School of Optometry, Indiana University, Bloomington, Indiana, USA
    Ophthalmic Physiol Opt 33:482-96. 2013
    ..To understand how primary and secondary spherical aberrations affect focusing of the retinal image and the measurement of refractive state in the accommodating eye...
  5. ncbi Where is the optimum far-point for a presbyopic eye?
    Larry N Thibos
    School of Optometry, Indiana University, Bloomington, IN 47405, USA
    J Refract Surg 24:970-5. 2008
    ..To resolve the presbyope's dilemma by determining the optimum location of the far-point that maximizes depth-of-field for reading printed text...
  6. ncbi The optics of wavefront sensing
    Larry N Thibos
    School of Optometry, Indiana University, 800 E Atwater Avenue, Bloomington, IN 47405, USA
    Ophthalmol Clin North Am 17:111-7, v. 2004
    ....
  7. doi Retinal image quality for virtual eyes generated by a statistical model of ocular wavefront aberrations
    Larry N Thibos
    School of Optometry, Indiana University, Bloomington, IN 47405, USA
    Ophthalmic Physiol Opt 29:288-91. 2009
    ..4, 329-351, 2004.), is representative of human eyes but slightly exaggerates the degradation of the retinal image caused by ocular aberrations. A demonstration program for producing virtual eyes is included as an Appendix to this paper...
  8. ncbi Accuracy and precision of objective refraction from wavefront aberrations
    Larry N Thibos
    School of Optometry, Indiana University, Bloomington, IN, USA
    J Vis 4:329-51. 2004
    ..If objective refractions are more precise than subjective refractions, then wavefront methods may become the new gold standard for specifying conventional and/or optimal corrections of refractive errors...
  9. ncbi Design principles and limitations of wave-front guided contact lenses
    Larry N Thibos
    School of Optometry, Indiana University, Bloomington, IN 47405, USA
    Eye Contact Lens 29:S167-70; discussion S190-1, S192-4. 2003
    ....
  10. ncbi Statistical variation of aberration structure and image quality in a normal population of healthy eyes
    Larry N Thibos
    School of Optometry, Indiana University, Bloomington, Indiana 47405, USA
    J Opt Soc Am A Opt Image Sci Vis 19:2329-48. 2002
    ..Different methods of computing population averages provided upper and lower limits to the mean optical transfer function and mean point-spread function for our population of eyes...
  11. ncbi Are higher order wavefront aberrations a moving target unworthy of clinical treatment?
    Larry N Thibos
    School of Optometry, Indiana University, Bloomington, IN 47405, USA
    J Refract Surg 18:744-5. 2002
  12. ncbi Spherical aberration of the reduced schematic eye with elliptical refracting surface
    L N Thibos
    School of Optometry, Indiana University, Bloomington, USA
    Optom Vis Sci 74:548-56. 1997
    ..A shape parameter value of approximately p = 0.6 provided the best fit of the model to selected data from the literature...
  13. ncbi Use of liquid-crystal adaptive-optics to alter the refractive state of the eye
    L N Thibos
    School of Optometry, Indiana University, Bloomington, USA
    Optom Vis Sci 74:581-7. 1997
    ..Undersampling may also be the factor which limits the useful dioptric range of the technique...
  14. ncbi Clinical applications of the Shack-Hartmann aberrometer
    L N Thibos
    School of Optometry, Indiana University, Bloomington 47405, USA
    Optom Vis Sci 76:817-25. 1999
    ..Taken together, spatial maps of the variation of optical aberrations and scatter across the eye's entrance pupil represents an improved description of the optical imperfections of the abnormal eye...
  15. ncbi Power vector analysis of the optical outcome of refractive surgery
    L N Thibos
    School of Optometry, Indiana University, Bloomington, Indiana 47405, USA
    J Cataract Refract Surg 27:80-5. 2001
    ..To demonstrate the power vector method of representing and analyzing spherocylindrical refractive errors...
  16. ncbi A statistical model of the aberration structure of normal, well-corrected eyes
    Larry N Thibos
    School of Optometry, Indiana University, Bloomington 47405, USA
    Ophthalmic Physiol Opt 22:427-33. 2002
    ..Potential applications of the model include computer simulation of individual variation in aberration structure, retinal image quality, visual performance, benefit of novel designs of ophthalmic lenses, or outcome of refractive surgery...
  17. pmc Peripheral refraction with and without contact lens correction
    Jie Shen
    School of Optometry, Indiana University, Bloomington, Indiana 47405, USA
    Optom Vis Sci 87:642-55. 2010
    ..The purpose of this study was to investigate the changes in refractive error across the horizontal visual field produced by contact lenses (CLs) and to quantify the effect of CLs on peripheral image blur...
  18. doi Measurement of the time course of optical quality and visual deterioration during tear break-up
    Haixia Liu
    School of Optometry, Indiana University, Bloomington, Indiana 47405, USA
    Invest Ophthalmol Vis Sci 51:3318-26. 2010
    ..To compare changes in optical quality and visual performance that accompany tear break-up (TBU) during blink suppression...
  19. ncbi Modeling the eye's optical system by ocular wavefront tomography
    Xin Wei
    School of Optometry, Indiana University, 800 East Atwater Ave, Bloomington, IN 47405, USA
    Opt Express 16:20490-502. 2008
    ..One goal of OWT is to create a customized schematic model eye that is anatomically similar and functionally equivalent to the individual eye over a large field of view...
  20. pmc Validation of an off-eye contact lens Shack-Hartmann wavefront aberrometer
    Pete Kollbaum
    Indiana University, School of Optometry, Bloomington, Indiana 47405, USA
    Optom Vis Sci 85:E817-28. 2008
    ..To evaluate the ability of a commercially available single pass Shack-Hartmann aberrometer to evaluate contact lens aberrations...
  21. pmc Design and validation of a scanning Shack Hartmann aberrometer for measurements of the eye over a wide field of view
    Xin Wei
    School of Optometry, Indiana University, Bloomington, Indiana 47405, USA
    Opt Express 18:1134-43. 2010
    ..02microm, 4mm pupil) and precisely (<0.03microm, 4mm pupil). A preliminary experiment with a human subject suggests its feasibility in clinical applications...
  22. pmc The mechanisms of vision loss associated with a cotton wool spot
    Toco Y P Chui
    School of Optometry, Indiana University, 800 E Atwater Ave, Bloomington, IN 47405, USA
    Vision Res 49:2826-34. 2009
    ..The different levels of loss associated with the arcuate and focal scotomas indicate different underlying pathologies...
  23. ncbi Estimating visual quality from wavefront aberration measurements
    Xu Cheng
    Indiana University, School of Optometry, 800 E Atwater Ave, Bloomington, IN 47405, USA
    J Refract Surg 19:S579-84. 2003
    ..We describe the most important metrics of optical quality, which are being investigated to predict vision quality and visual performance...
  24. pmc Design and validation of an infrared Badal optometer for laser speckle
    Danielle F W Teel
    School of Optometry, Indiana University, Bloomington, Indiana 47408, USA
    Optom Vis Sci 85:834-42. 2008
    ..The instrument was designed for subjective meridional refraction in infrared light by human patients...
  25. ncbi Calculation of retinal image quality for polychromatic light
    Sowmya Ravikumar
    School of Optometry, Indiana University, 800 E Atwater, Bloomington, IN 47405, USA
    J Opt Soc Am A Opt Image Sci Vis 25:2395-407. 2008
    ..The effect of typical levels of transverse chromatic aberration is virtually eliminated in the presence of longitudinal chromatic aberration and monochromatic aberrations. Clinical value and limitations of the method are discussed...
  26. doi Describing ocular aberrations with wavefront vergence maps
    Jayoung Nam
    Indiana University, Bloomington, IN 47405, USA
    Clin Exp Optom 92:194-205. 2009
    ..Finally, we discuss the advantages and limitations of vergence map representation of ocular aberrations...
  27. ncbi Zernike radial slope polynomials for wavefront reconstruction and refraction
    Jayoung Nam
    1School of Optometry, Indiana University, Bloomington, Indiana 47405, USA
    J Opt Soc Am A Opt Image Sci Vis 26:1035-48. 2009
    ..Zernike coefficients for wavefront error can be recovered from the coefficients of radial slope polynomials, thereby offering an alternative way to perform wavefront reconstruction...
  28. ncbi Retinal stretching limits peripheral visual acuity in myopia
    Toco Y P Chui
    Department of Optometry and Radiography, Hong Kong Polytechnic University, Hong Kong
    Vision Res 45:593-605. 2005
    ..Stretching appears to be locally uniform over the central +/-15 degrees of visual field but is globally non-uniform since the foveal region appears to stretch more than the globe itself...
  29. ncbi Relationship between refractive error and monochromatic aberrations of the eye
    Xu Cheng
    School of Optometry, Indiana University, Bloomington, Indiana 47405, USA
    Optom Vis Sci 80:43-9. 2003
    ..To examine the relationship between ametropia and optical aberrations in a population of 200 normal human eyes with refractive errors spanning the range from +5.00 to -10.00 D...
  30. ncbi Measuring ocular aberrations and image quality in peripheral vision with a clinical wavefront aberrometer
    Jie Shen
    School of Optometry, Indiana University, 800 E Atwater Avenue, Bloomington IN 47405, USA
    Clin Exp Optom 92:212-22. 2009
    ..The purpose of this study was to evaluate these concerns experimentally using a physical eye model...
  31. ncbi Use of retroillumination to visualize optical aberrations caused by tear film break-up
    Nikole L Himebaugh
    School of Optometry, Indiana University, Bloomington, Indiana 47405, USA
    Optom Vis Sci 80:69-78. 2003
    ..The aim of the current study was to develop quantitative methods to assess optical aberrations caused by tear film disruption...
  32. ncbi Predicting subjective judgment of best focus with objective image quality metrics
    Xu Cheng
    School of Optometry, Indiana University, Bloomington, IN, USA
    J Vis 4:310-21. 2004
    ..To determine the impact of higher-order monochromatic aberrations on lower-order subjective sphero-cylindrical refractions...
  33. ncbi Validation of a combined corneal topographer and aberrometer based on Shack-Hartmann wave-front sensing
    Fan Zhou
    School of Optometry, Indiana University, Bloomington, Indiana 47405, USA
    J Opt Soc Am A Opt Image Sci Vis 21:683-96. 2004
    ..2 microm) and appreciable levels of trefoil (0.08-0.47 microm), coma (0.14-0.19 microm), and spherical aberration (0.18-0.25 microm). The mean values of these aberrations were significantly larger than the RMS in repeated measurements...
  34. ncbi Test-retest reliability of clinical Shack-Hartmann measurements
    Xu Cheng
    School of Optometry, Indiana University, Bloomington, Indiana 47405, USA
    Invest Ophthalmol Vis Sci 45:351-60. 2004
    ..To evaluate the stability of clinical monochromatic aberrometry measurements over a wide range of time scales...
  35. doi Modal estimation of wavefront phase from slopes over elliptical pupils
    Xin Wei
    School of Optometry, Indiana University, Bloomington, Indiana 47405, USA
    Optom Vis Sci 87:E767-77. 2010
    ..Such methods for modal estimation of wavefront aberrations are sensitive to pupil shape...
  36. ncbi Standards for reporting the optical aberrations of eyes
    Larry N Thibos
    School of Optometry, Indiana University, Bloomington, USA
    J Refract Surg 18:S652-60. 2002
    ..Progress reports were presented at the 1999 OSA annual meeting and at VSIA-2000 by the chairs of three taskforce subcommittees on (1) reference axes, (2) describing functions, and (3) model eyes...
  37. ncbi Validation of a clinical Shack-Hartmann aberrometer
    Xu Cheng
    School of Optometry, Indiana University, 800 E, Atwater Avenue, Bloomington, IN 47405, USA
    Optom Vis Sci 80:587-95. 2003
    ..To validate the accuracy, tolerance, and repeatability of the complete ophthalmic analysis system aberrometer (COAS, Wavefront Sciences Inc.) with model eyes and normal human eyes...
  38. pmc Visual impact of Zernike and Seidel forms of monochromatic aberrations
    Xu Cheng
    School of Optometry, Indiana University, Bloomington, Indiana 47405, USA
    Optom Vis Sci 87:300-12. 2010
    ..The aim of this study was to examine the impact of different aberrations modes (e.g., coma, astigmatism, spherical aberration [SA]) and different aberration basis functions (Zernike or Seidel) on visual acuity (VA)...
  39. ncbi Predicting optical effects of tear film break up on retinal image quality using the Shack-Hartmann aberrometer and computational optical modeling
    Nikole L Himebaugh
    School of Optometry, Indiana University, Bloomington, Indiana, USA
    Adv Exp Med Biol 506:1141-7. 2002
  40. pmc Unbiased estimation of refractive state of aberrated eyes
    Jesson Martin
    Indiana University, School of Optometry, Bloomington, IN 47405, USA
    Vision Res 51:1932-40. 2011
    ..Thus a variety of image quality metrics may be used to determine ocular refractive state for monochromatic (635nm) light, thereby achieving accurate results without the need for empirical correction factors...
  41. ncbi Validation of a Hartmann-Moiré wavefront sensor with large dynamic range
    Xin Wei
    School of Optometry, Indiana University, Bloomington, Indiana 47405, USA
    Opt Express 17:14180-5. 2009
    ..01D. Conclusion: The Hartmann-Moiré wavefront sensor measures defocus and astigmatism accurately and repeatedly with good sensitivity over a large dynamic range required for ophthalmic applications...
  42. ncbi Comparison of monochromatic ocular aberrations measured with an objective cross-cylinder aberroscope and a Shack-Hartmann aberrometer
    Xin Hong
    School of Optometry, Indiana University, Bloomington, Indiana 47405 3680, USA
    Optom Vis Sci 80:15-25. 2003
    ..Multivariate statistical analysis indicated that the SH aberrometer discriminated between subjects much better than did the objective aberroscope...
  43. doi Wavelength adjustment using an eye model from aberrometry data
    Jayoung Nam
    School of Optometry, Indiana University, Bloomington, Indiana 47405, USA
    J Opt Soc Am A Opt Image Sci Vis 27:1561-74. 2010
    ..In addition, we provide a method of finding the chief ray using back-projection in some cases and discuss different meanings of prism...
  44. pmc Metrics of retinal image quality predict visual performance in eyes with 20/17 or better visual acuity
    Raymond A Applegate
    Visual Optics Institute, College of Optometry, University of Houston, Houston, Texas 77204 2020, USA
    Optom Vis Sci 83:635-40. 2006
    ....
  45. ncbi Metrics of optical quality derived from wave aberrations predict visual performance
    Jason D Marsack
    College of Optometry, University of Houston, Houston, TX 77204, USA
    J Vis 4:322-8. 2004
    ..25 microm over a 6-mm pupil. The best metric, called the visual Strehl ratio, accounts for 81% of the variance in high-contrast logMAR acuity...
  46. ncbi Measuring visual acuity--mesopic or photopic conditions, and high or low contrast letters?
    Konrad Pesudovs
    Visual Optics Institute, College of Optometry, University of Houston, Houston, TX 77204 2020, USA
    J Refract Surg 20:S508-14. 2004
    ..The purpose of this study is to explore whether photopic high contrast visual acuity (VA) is an appropriate visual performance reference and whether mesopic and/or low contrast testing provides any advantage...
  47. ncbi Videokeratoscope-line-of-sight misalignment and its effect on measurements of corneal and internal ocular aberrations
    Thomas O Salmon
    College of Optometry, Northeastern State University, Tahlequah, Oklahoma 74464, USA
    J Opt Soc Am A Opt Image Sci Vis 19:657-69. 2002
    ....
  48. ncbi The filtered Fourier difference spectrum predicts psychophysical letter discrimination in the peripheral retina
    Roger S Anderson
    Vision Science Research Group, School of Biomedical Sciences, University of Ulster at Coleraine, Northern Ireland, UK
    Spat Vis 17:5-15. 2004
    ..These results imply that the band of frequencies between zero and 1.25 cycles/letter are most important for letter discrimination in peripheral vision...
  49. ncbi Aberrometry: clinical and research applications
    Raymond A Applegate
    Optom Vis Sci 80:85-6. 2003
  50. ncbi Nonveridical visual perception in human amblyopia
    Brendan T Barrett
    Department of Optometry, University of Bradford, Bradford, United Kingdom
    Invest Ophthalmol Vis Sci 44:1555-67. 2003
    ..However, there are few examples of these perceptual errors in the literature. This study was an investigation of the prevalence and nature of misperceptions in human amblyopia...
  51. ncbi Aberrometry: the past, present, and future of optometry
    Larry N Thibos
    Optom Vis Sci 80:1-2. 2003

Research Grants23

  1. OPTICAL AND RETINAL LIMITS TO HUMAN VISUAL PERFORMANCE
    Larry Thibos; Fiscal Year: 2004
    ....
  2. OPTICAL AND RETINAL LIMITS TO HUMAN VISUAL PERFORMANCE
    Larry Thibos; Fiscal Year: 2007
    ..Project 6. Develop a new concept of wavefront tomography to characterize the 3-dimensional structure of the eye's optical system from a series of wavefront measurements along multiple lines-of-sight. ..
  3. OPTICAL AND RETINAL LIMITS TO HUMAN VISUAL PERFORMANCE
    Larry Thibos; Fiscal Year: 1993
    ..The investigators also propose to examine the importance of axial pupil location on the modulation transfer function of the model eye and to extend these theoretical calculations to include color contrast...
  4. FUNCTIONAL ANALYSIS OF RETINAL GANGLION CELLS
    Larry Thibos; Fiscal Year: 1990
    ....
  5. OPTICAL AND RETINAL LIMITS TO VISUAL PERFORMANCE
    Larry Thibos; Fiscal Year: 1999
    ..For this purpose, the principal investigator proposes to develop a novel technique for measuring the optical transfer function of the eye objectively. ..
  6. OPTICAL AND RETINAL LIMITS TO HUMAN VISUAL PERFORMANCE
    Larry N Thibos; Fiscal Year: 2010
    ..Project 6. Develop a new concept of wavefront tomography to characterize the 3-dimensional structure of the eye's optical system from a series of wavefront measurements along multiple lines-of-sight. ..