Research Topics
Species | W N StrotherSummaryAffiliation: Indiana University Country: USA Publications
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Publications
Long-term effects of early cocaine exposure on the light responsiveness of the adult circadian timing systemW N Strother
Department of Cell Biology, Neurobiology, and Anatomy, University of Cincinnati College of Medicine, OH, USA
Neurotoxicol Teratol 20:555-64. 1998..Together with the recent demonstration of D1 receptors in the human SCN, these findings raise the possibility that gestational cocaine abuse by humans may also lead to later disturbances in the circadian timing system...
Regional central nervous system densities of delta-opioid receptors in alcohol-preferring P, alcohol-nonpreferring NP, and unselected Wistar ratsW N Strother
Department of Psychiatry, Institute of Psychiatric Research, 791 Union Drive, Indianapolis, IN 46202 4887, USA
Alcohol 25:31-8. 2001....
Regional CNS densities of serotonin 1A and dopamine D2 receptors in periadolescent alcohol-preferring P and alcohol-nonpreferring NP rat pupsWendy N Strother
Department of Psychiatry, Institute of Psychiatric Research, Indiana University Medical Center, Indiana University School of Medicine, 791 Union Drive, Indianapolis, IN 46202 4887, USA
Pharmacol Biochem Behav 74:335-42. 2003....
Acute ethanol effects on local cerebral glucose utilization in select central nervous system regions of adolescent alcohol-preferring (P) and alcohol-nonpreferring (NP) ratsWendy N Strother
Institute of Psychiatric Research, Indiana University School of Medicine, Indianapolis, Indiana 46202 4887, USA
Alcohol Clin Exp Res 32:1875-83. 2008..The 2-[(14)C]deoxyglucose (2-DG) technique allows for the in vivo quantification of local cerebral glucose utilization (LCGU) as a measure of functional neuronal activity...
Effects of acute administration of ethanol on cerebral glucose utilization in adult alcohol-preferring and alcohol-nonpreferring ratsWendy N Strother
Institute of Psychiatric Research, Indiana University School of Medicine, Indianapolis, IN 46202 4887, USA
Alcohol 35:119-28. 2005..These findings support the suggestion that certain central nervous system regions of P rats may be more sensitive than those of NP rats to the effects of low to intermediate doses of ethanol...
Dopamine and serotonin content in select brain regions of weanling and adult alcohol drinking rat linesWendy N Strother
Department of Psychiatry and Institute of Psychiatric Research, 791 Union Drive, Indianapolis, IN, 46202 4887, USA
Pharmacol Biochem Behav 80:229-37. 2005..These results confirm previous findings of an association between innate low DA content in select limbic regions and high alcohol drinking behavior...
Candidate genes, pathways and mechanisms for alcoholism: an expanded convergent functional genomics approachZ A Rodd
Department of Psychiatry, Institute of Psychiatric Research, Indiana University School of Medicine, Indianapolis, IN 46202, USA
Pharmacogenomics J 7:222-56. 2007..In conjunction with a higher reactivity to its rewarding effects, they may able to ingest enough of this nonspecific drug for a strong hedonic and addictive effect to occur...
Protein expression changes in the nucleus accumbens and amygdala of inbred alcohol-preferring rats given either continuous or scheduled access to ethanolR L Bell
Institute of Psychiatric Research and Department of Psychiatry, Indiana University School of Medicine, Indianapolis, IN 46202, USA
Alcohol 40:3-17. 2006..This may reflect differences in neuroanatomical and/or functional characteristics associated with EtOH self-administration and possibly withdrawal, between these two brain structures...
Gene expression in the hippocampus of inbred alcohol-preferring and -nonpreferring ratsH J Edenberg
Department of Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis, IN 46202-4887, USA
Genes Brain Behav 4:20-30. 2005....
D1-dopamine receptor binding and tyrosine hydroxylase-immunoreactivity in the fetal and neonatal hamster suprachiasmatic nucleusW N Strother
Department of Cell Biology, Neurobiology, and Anatomy, University of Cincinnati College of Medicine, OH 45267, USA
Brain Res Dev Brain Res 106:137-44. 1998..However, a receptor-transmitter mismatch exists between D1-dopamine receptors and TH-immunoreactive fibers in the fetal SCN suggesting that the role of dopamine in maternal-fetal entrainment may be as a paracrine or humoral signal...
Adolescent alcohol drinking and its long-range consequences. Studies with animal modelsWilliam J McBride
Indiana University School of Medicine, Institute of Psychiatric Research, Indianapolis, Indiana 46202-4887, USA
Recent Dev Alcohol 17:123-42. 2005..With suitable animal models, a better understanding of the mechanisms underlying adolescent alcohol drinking and its long-range consequences can be attained...
alpha-Synuclein maps to a quantitative trait locus for alcohol preference and is differentially expressed in alcohol-preferring and -nonpreferring ratsTiebing Liang
Department of Medicine, Indiana University School of Medicine, Indianapolis, IN 46202, USA
Proc Natl Acad Sci U S A 100:4690-5. 2003..These results suggest that differential expression of the alpha-synuclein gene may contribute to alcohol preference in the iP rats...
Drd2 expression in the high alcohol-preferring and low alcohol-preferring micePaula J Bice
Department of Medicine, Indiana University School of Medicine, Medical Research and Library Building, Room 411, 975 W Walnut St, Indianapolis, IN, 46202, USA
Mamm Genome 19:69-76. 2008..These results suggest that the SNP may play a role in the differential expression of Drd2 between the HAP and LAP mice and that the polymorphism in Drd2 may contribute to alcohol preference...
Functional gene expression differences between inbred alcohol-preferring and -non-preferring rats in five brain regionsMark W Kimpel
Department of Psychiatry, Indiana University School of Medicine, Indianapolis, IN 46202 4887, USA
Alcohol 41:95-132. 2007..The many regional and overall gene expression differences between the iP and iNP rat lines may contribute to the divergent alcohol drinking phenotypes of these rats...
Differential gene expression in the nucleus accumbens with ethanol self-administration in inbred alcohol-preferring ratsZachary A Rodd
Department of Psychiatry, Indiana University School of Medicine, Indianapolis, IN 46202 4887, United States
Pharmacol Biochem Behav 89:481-98. 2008..g., Cav2, Nrxn3, Gabrb2, Gad1, Homer1) and homeostasis (S100b, Prkca, Ftl1) categories. Overall, the results suggest that changes in gene expression in the ACB of iP rats are associated with the reinforcing effects of EtOH...
Gene expression changes in the nucleus accumbens of alcohol-preferring rats following chronic ethanol consumptionRichard L Bell
Department of Psychiatry, Indiana University Purdue University at Indianapolis, Indianapolis, IN 46202, USA
Pharmacol Biochem Behav 94:131-47. 2009..Conversely, chronic MSA drinking, with its associated protracted withdrawal periods, results in genomic changes that may be masked by tight regulation of these genes following repeated experiences of ethanol withdrawal...
Alcohol effects on central nervous system gene expression in genetic animal modelsWilliam J McBride
Indiana University School of Medicine, Indianapolis, Indiana, USA
Alcohol Clin Exp Res 29:167-75. 2005..Hashimoto and Kristine M. Wiren...
Innate differences in protein expression in the nucleus accumbens and hippocampus of inbred alcohol-preferring and -nonpreferring ratsFrank A Witzmann
Department of Cellular and Integrative Physiology, Biotechnology Research and Training Center, Indiana University School of Medicine, 1345 W 16th Street, Indianapolis, IN 46202, USA
Proteomics 3:1335-44. 2003....
Proteomics and alcoholismFrank A Witzmann
Department of Cellular and Integrative Physiology, Indiana University School of Medicine, Indianapolis, IN 46202, USA
Int Rev Neurobiol 61:189-214. 2004
Neuroimaging of rodent and primate models of alcoholism: initial reports from the integrative neuroscience initiative on alcoholismEdith V Sullivan
Department of Psychiatry and Behavioral Sciences and Neuroscience Program, Stanford University School of Medicine, Stanford, California 94305 5723, USA
Alcohol Clin Exp Res 29:287-94. 2005....
