Research Topics
Species | Deborah K SokolSummaryAffiliation: Indiana University Country: USA Publications
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Detail Information
Publications
Neuroimaging in autistic spectrum disorder (ASD)Deborah K Sokol
Department of Neurology, Indiana University School of Medicine, 702 Barnhill Drive, R1 1757, Indianapolis, IN 46202, USA
J Neuroimaging 14:8-15. 2004..Despite 30 years of research, a reliable marker for ASD has not been identified. Therefore, routine neuroimaging for individuals with ASD is not recommended...- Antiphospholipid antibodies in blood and cerebrospinal fluids of patients with psychosisDeborah K Sokol
Indiana University School of Medicine, Department of Neurology 575 West Drive XE 40 Indianapolis, IN 46202, USA
J Neuroimmunol 190:151-6. 2007.... - Hydrogen proton magnetic resonance spectroscopy in autism: preliminary evidence of elevated choline/creatine ratioDeborah K Sokol
Department of Neurology, Indiana University School of Medicine, Indianapolis, USA
J Child Neurol 17:245-9. 2002..Recent neuropathologic evidence has implicated disruption of acetylcholine transmission in the brains of autistic adults. A case-controlled study of hydrogen proton magnetic resonance spectroscopy choline/creatine ratios is warranted... - Antiphospholipid and glutamic acid decarboxylase antibodies in patients with focal epilepsyD K Sokol
Department of Neurology, Indiana University School of Medicine, Riley Hospital for Children, Indianapolis 46202, USA
Neurology 62:517-8. 2004 
Anti-phospholipid antibodies in cerebrospinal fluid but not serum from a boy with psychosisDeborah K Sokol
Department of Neurology, Indiana University School of Medicine, Indianapolis, Indiana 46202, USA
Pediatr Neurol 39:293-4. 2008..This finding is consistent with a recent report of antiphospholipid antibodies found in the cerebrospinal fluid of adults with acute psychosis...- High levels of Alzheimer beta-amyloid precursor protein (APP) in children with severely autistic behavior and aggressionDeborah K Sokol
Department of Neurology, Indiana University School of Medicine, 702 Barnhill Drive, Indianapolis, IN 46202, USA
J Child Neurol 21:444-9. 2006..This favors an increased alpha-secretase pathway in autism (anabolic), opposite to what is seen in Alzheimer disease. Additionally, a complex relationship between age, acetylcholinesterase, and plasma neuronal markers was found... 
Increased secreted amyloid precursor protein-α (sAPPα) in severe autism: proposal of a specific, anabolic pathway and putative biomarkerBalmiki Ray
Department of Psychiatry, Institute of Psychiatric Research, Indiana University School of Medicine, Indianapolis, Indiana, United States of America
PLoS ONE 6:e20405. 2011..Taken together, this study provides evidence that sAPPα levels are generally elevated in severe autism and suggests that these patients may have aberrant non-amyloidogenic processing of APP...- Contrasting the neurologic complications of cardiac transplantation in adults and childrenThomas O Mayer
Department of Neurology, Indiana University School of Medicine, Indianapolis 46202 5124, USA
J Child Neurol 17:195-9. 2002..However, peripheral neuropathies tend to occur more frequently in adults than in children (P = .04), and the types of complications in the immediate post-transplant period seem to differ... - Autism, Alzheimer disease, and fragile X: APP, FMRP, and mGluR5 are molecular linksD K Sokol
Department of Neurology, Indiana University School of Medicine, 791 Union Drive, Indianapolis, IN 46202, USA
Neurology 76:1344-52. 2011..Treatment with mGluR antagonists may help repress APP mRNA translation and reduce secretion of sAPP in FXS and perhaps autism... - Early cognitive and behavioral problems in children with nodular heterotopiaMarcia V Felker
Department of Neurology, Indiana University School of Medicine, Indianapolis, IN, USA
Epilepsy Behav 22:523-6. 2011..These findings demonstrate that reading dysfluency can be evident in children with nodular heterotopia, even in the absence of epilepsy, but also highlight difficulties with behavior in this population... - From swelling to sclerosis: acute change in mesial hippocampus after prolonged febrile seizureDeborah K Sokol
Indiana University School of Medicine, Indianapolis, IN, USA
Seizure 12:237-40. 2003..All had left focal seizures followed by right MTS. Our patient demonstrates a shorter interval for the radiologic development of hippocampal sclerosis compared to other reports... - Absolute pitch in a four-year-old boy with autismJames N Brenton
Pediatric Section, Department of Neurology, Indiana University School of Medicine, Indianapolis, Indiana 46202, USA
Pediatr Neurol 39:137-8. 2008..Further, the identification of absolute pitch in even young children with autism may lead to a lifelong skill... - Like father, like son: periventricular nodular heterotopia and nonverbal learning disorderMarcia V McCann
Department of Neurology, Division of Pediatric Neurology, Indiana University, Indianapolis, Indiana 46202, USA
J Child Neurol 23:950-3. 2008..We present a father and son with bilateral periventricular nodular heterotopia and similar visual-spatial learning deficits, consistent with nonverbal learning disability... - Gene associated with seizures, autism, and hepatomegaly in an Amish girlChristopher Jackman
Department of Neurology, Indiana University School of Medicine, Indianapolis, Indiana, USA
Pediatr Neurol 40:310-3. 2009..This patient exhibited the additional features of periventricular leukomalacia and hepatomegaly... - Anti-N-methyl-D-aspartate receptor encephalitis: early treatment is beneficialErin H Breese
Department of Pediatrics, Indiana University School of Medicine, Indianapolis, Indiana, USA
Pediatr Neurol 42:213-4. 2010..Early diagnosis and treatment with immune globulin and steroids resulted in near-complete recovery... - Neuropsychologic outcomes in a case series of twins discordant for perinatal strokeTasneem L Talib
Division of Pediatric Neurology, Department of Neurology, Roudebush Veterans Affairs Medical Center Health Services, Indiana University School of Medicine, Indianapolis, Indiana 46202, USA
Pediatr Neurol 38:118-25. 2008..Twin gestation may be a risk factor for poor cognitive outcome after perinatal stroke. Large infarct size and comorbid epilepsy may have contributed to some of the poor cognitive outcomes in this cohort... - Testing for antiphospholipid antibody (aPL) specificities in retrospective "normal" cerebral spinal fluid (CSF)D K Sokol
Department of Neurology, Indiana University School of Medicine, Indianapolis, IN 46202, USA
Clin Dev Immunol 11:7-12. 2004..Seven of 10 patients with elevated CSF values were females. As expected, most "normal" aPL OD values were substantially lower in CSF than those we have reported in blood samples from volunteer blood donors... - LaCrosse viral encephalitis mimics herpes simplex viral encephalitisD K Sokol
Department of Neurology, James Whitcomb Riley Hospital for Children, Indiana University Medical Center, Indianapolis, Indiana 46202 5200, USA
Pediatr Neurol 25:413-5. 2001..The recently developed LaCrosse RNA polymerase chain reaction for cerebrospinal fluid may enable rapid diagnosis, prevent the need for treatment with acyclovir, and give parents an encouraging prognosis... - Reading impairment in the neuronal migration disorder of periventricular nodular heterotopiaDeborah K Sokol
Neurology 66:294; author reply 294. 2006