Changyu Shen

Summary

Affiliation: Indiana University
Country: USA

Publications

  1. ncbi request reprint A mixed-effects model for cognitive decline with non-monotone non-response from a two-phase longitudinal study of dementia
    Changyu Shen
    Division of Biostatistics, School of Medicine, Indiana University, Indianapolis, IN 46202, USA
    Stat Med 26:409-25. 2007
  2. pmc Comparison of computational algorithms for the classification of liver cancer using SELDI mass spectrometry: a case study
    Changyu Shen
    Division of Biostatistics, Department of Medicine, Indiana University School of Medicine, Indianapolis, IN 46202, USA
    Cancer Inform 3:329-39. 2007
  3. ncbi request reprint A hierarchical statistical model to assess the confidence of peptides and proteins inferred from tandem mass spectrometry
    Changyu Shen
    Division of Biostatistics, Department of Medicine, Indiana University School of Medicine, Indianapolis, IN 46202, USA
    Bioinformatics 24:202-8. 2008
  4. pmc Sensitivity analysis for causal inference using inverse probability weighting
    Changyu Shen
    Division of Biostatistics, Department of Medicine, Indiana University School of Medicine, Indianapolis, IN 46202, USA
    Biom J 53:822-37. 2011
  5. pmc On the estimation of false positives in peptide identifications using decoy search strategy
    Changyu Shen
    Division of Biostatistics, Indiana University School of Medicine, Indianapolis, IN 46202, USA
    Proteomics 9:194-204. 2009
  6. ncbi request reprint A copula model for repeated measurements with non-ignorable non-monotone missing outcome
    Changyu Shen
    Division of Biostatistics, School of Medicine, Indiana University, 1050 Wishard Boulevard RG R4101, Indianapolis, IN 46202, USA
    Stat Med 25:2427-40. 2006
  7. ncbi request reprint Application of pattern-mixture models to outcomes that are potentially missing not at random using pseudo maximum likelihood estimation
    Changyu Shen
    Division of Biostatistics, School of Medicine, Indiana University, 1050 Wishard Boulevard RG R4101, Indianapolis, IN 46202, USA
    Biostatistics 6:333-47. 2005
  8. pmc A modulated empirical Bayes model for identifying topological and temporal estrogen receptor α regulatory networks in breast cancer
    Changyu Shen
    Center for Computational Biology, Indiana University School of Medicine, Indianapolis, IN 46202, USA
    BMC Syst Biol 5:67. 2011
  9. pmc Epigenetic resensitization to platinum in ovarian cancer
    Daniela Matei
    Melvin and Bren Simon Cancer Center, Indiana University, Bloomington, Indiana 46202, USA
    Cancer Res 72:2197-205. 2012
  10. pmc Model-based peak alignment of metabolomic profiling from comprehensive two-dimensional gas chromatography mass spectrometry
    Jaesik Jeong
    Department of Biostatistics, Indiana University, Indianapolis, IN 46202, USA
    BMC Bioinformatics 13:27. 2012

Detail Information

Publications59

  1. ncbi request reprint A mixed-effects model for cognitive decline with non-monotone non-response from a two-phase longitudinal study of dementia
    Changyu Shen
    Division of Biostatistics, School of Medicine, Indiana University, Indianapolis, IN 46202, USA
    Stat Med 26:409-25. 2007
    ..A second simulation illustrates the magnitude of the bias in estimating the difference of decline rate between two groups when the random effects are linked in different manners for the two groups...
  2. pmc Comparison of computational algorithms for the classification of liver cancer using SELDI mass spectrometry: a case study
    Changyu Shen
    Division of Biostatistics, Department of Medicine, Indiana University School of Medicine, Indianapolis, IN 46202, USA
    Cancer Inform 3:329-39. 2007
    ..In this report, we describe a comparative case study on the classification accuracy of hepatocellular carcinoma based on the serum proteomic pattern generated from a Surface Enhanced Laser Desorption/Ionization (SELDI) mass spectrometer...
  3. ncbi request reprint A hierarchical statistical model to assess the confidence of peptides and proteins inferred from tandem mass spectrometry
    Changyu Shen
    Division of Biostatistics, Department of Medicine, Indiana University School of Medicine, Indianapolis, IN 46202, USA
    Bioinformatics 24:202-8. 2008
    ..Although many approaches have been developed to assign confidence measure from different perspectives, a unified statistical framework that integrates the uncertainty of peptides and proteins is still missing...
  4. pmc Sensitivity analysis for causal inference using inverse probability weighting
    Changyu Shen
    Division of Biostatistics, Department of Medicine, Indiana University School of Medicine, Indianapolis, IN 46202, USA
    Biom J 53:822-37. 2011
    ..We illustrate our method with two medical data sets...
  5. pmc On the estimation of false positives in peptide identifications using decoy search strategy
    Changyu Shen
    Division of Biostatistics, Indiana University School of Medicine, Indianapolis, IN 46202, USA
    Proteomics 9:194-204. 2009
    ....
  6. ncbi request reprint A copula model for repeated measurements with non-ignorable non-monotone missing outcome
    Changyu Shen
    Division of Biostatistics, School of Medicine, Indiana University, 1050 Wishard Boulevard RG R4101, Indianapolis, IN 46202, USA
    Stat Med 25:2427-40. 2006
    ..The proposed method is then applied to one example from a community cohort study to demonstrate its capability to reduce bias...
  7. ncbi request reprint Application of pattern-mixture models to outcomes that are potentially missing not at random using pseudo maximum likelihood estimation
    Changyu Shen
    Division of Biostatistics, School of Medicine, Indiana University, 1050 Wishard Boulevard RG R4101, Indianapolis, IN 46202, USA
    Biostatistics 6:333-47. 2005
    ..We apply the proposed method to an epidemiologic cohort study to examine cognition decline among elderly...
  8. pmc A modulated empirical Bayes model for identifying topological and temporal estrogen receptor α regulatory networks in breast cancer
    Changyu Shen
    Center for Computational Biology, Indiana University School of Medicine, Indianapolis, IN 46202, USA
    BMC Syst Biol 5:67. 2011
    ..Dynamic gene expression changes have been shown to characterize the breast cancer cell response to estrogens, the every molecular mechanism of which is still not well understood...
  9. pmc Epigenetic resensitization to platinum in ovarian cancer
    Daniela Matei
    Melvin and Bren Simon Cancer Center, Indiana University, Bloomington, Indiana 46202, USA
    Cancer Res 72:2197-205. 2012
    ....
  10. pmc Model-based peak alignment of metabolomic profiling from comprehensive two-dimensional gas chromatography mass spectrometry
    Jaesik Jeong
    Department of Biostatistics, Indiana University, Indianapolis, IN 46202, USA
    BMC Bioinformatics 13:27. 2012
    ..However, there is still much experimental variation to be controlled including both within-experiment and between-experiment variation. For efficient analysis, an ideal peak alignment method to deal with such variations is in great need...
  11. pmc RNA polymerase II binding patterns reveal genomic regions involved in microRNA gene regulation
    Guohua Wang
    Center for Computational Biology and Bioinformatics, Indiana University School of Medicine, Indianapolis, Indiana, United States of America
    PLoS ONE 5:e13798. 2010
    ....
  12. pmc Worsening endothelial function with efavirenz compared to protease inhibitors: a 12-month prospective study
    Samir K Gupta
    Division of Infectious Diseases, Department of Medicine, Indiana University School of Medicine, Indianapolis, IN, USA
    PLoS ONE 7:e45716. 2012
    ....
  13. doi request reprint Computer-generated reminders and quality of pediatric HIV care in a resource-limited setting
    Martin C Were
    Department of Medicine, Indiana University School of Medicine, Indianapolis, IN 46254, USA
    Pediatrics 131:e789-96. 2013
    ..To evaluate the impact of clinician-targeted computer-generated reminders on compliance with HIV care guidelines in a resource-limited setting...
  14. pmc Neither proteinuria nor albuminuria is associated with endothelial dysfunction in HIV-infected patients without diabetes or hypertension
    Samir K Gupta
    Division of Infectious Diseases, Indiana University School of Medicine, Indianapolis, IN 46202, USA
    J Infect Dis 204:1946-50. 2011
    ..None of the renal markers, modeled as either continuous or categorical variables, correlated with FMD. Contrary to expectations, endothelial dysfunction may not be the link between nephropathy and CVD in HIV...
  15. pmc Evaluation of computer-generated reminders to improve CD4 laboratory monitoring in sub-Saharan Africa: a prospective comparative study
    Martin C Were
    Indiana University School of Medicine, Indianapolis, Indiana, USA
    J Am Med Inform Assoc 18:150-5. 2011
    ..This study tested the hypothesis that clinical summaries with computer-generated reminders could improve clinicians' compliance with CD4 testing guidelines in the resource-limited setting of sub-Saharan Africa...
  16. pmc An efficient post-hoc integration method improving peak alignment of metabolomics data from GCxGC/TOF-MS
    Jaesik Jeong
    Department of Biostatistics, 410 West 10th st, Indianapolis, IN 46202, USA
    BMC Bioinformatics 14:123. 2013
    ..Therefore, a post-hoc approach, which integrates both identification and alignment results, is in urgent need for the purpose of increasing the accuracy of peak alignment...
  17. pmc Evaluating a scalable model for implementing electronic health records in resource-limited settings
    Martin C Were
    Indiana University School of Medicine, Indianapolis, Indiana, USA
    J Am Med Inform Assoc 17:237-44. 2010
    ..004) and with pharmacy by 63% (p<0.001). Surveyed providers were highly satisfied with the EHRs and its support infrastructure. This model offers a viable approach for broadly implementing EHRs in resource-limited settings...
  18. pmc A mixture model approach in gene-gene and gene-environmental interactions for binary phenotypes
    Lang Li
    Division of Biostatistics, Department of Medicine, Indiana University, Indianapolis, Indiana46202, USA
    J Biopharm Stat 18:1150-77. 2008
    ..The mixture model approach has the highest recovery probability to recover the true partition in the simulation studies. Its applications are exemplified in interim data analyses for two cancer studies...
  19. pmc No impairment of endothelial function or insulin sensitivity with 4 weeks of the HIV protease inhibitors atazanavir or lopinavir-ritonavir in healthy subjects without HIV infection: a placebo-controlled trial
    Michael P Dube
    Division of Infectious Diseases, Department of Medicine, Indiana University School of Medicine, Indianapolis, USA
    Clin Infect Dis 47:567-74. 2008
    ..Some PIs, such as indinavir, directly induce endothelial dysfunction, an effect that may mediate that portion of the increase in cardiovascular events that is not attributable to dyslipidemia...
  20. pmc An empirical Bayes model for gene expression and methylation profiles in antiestrogen resistant breast cancer
    Jaesik Jeong
    Department of Medicine Division of Biostatistics, Indiana University, Indianapolis, IN, USA
    BMC Med Genomics 3:55. 2010
    ....
  21. doi request reprint Dual targeting of EphA2 and ER restores tamoxifen sensitivity in ER/EphA2-positive breast cancer
    Yesim Gokmen-Polar
    Department of Medicine, Indiana University School of Medicine, Indianapolis, IN, USA
    Breast Cancer Res Treat 127:375-84. 2011
    ..Our data demonstrate that dual targeting of EphA2 and ER is a promising approach for delaying resistance to Tamoxifen. The data support our hypothesis that EphA2 impacts ER function via a FAK dependent pathway...
  22. doi request reprint Fragmented wide QRS on a 12-lead ECG: a sign of myocardial scar and poor prognosis
    Mithilesh K Das
    Krannert Institute of Cardiology, Roudebush VA Medical Center, Indiana University School of Medicine, Indianapolis, IN 46202, USA
    Circ Arrhythm Electrophysiol 1:258-68. 2008
    ..We postulate that fragmented wQRS (f-wQRS) due to bundle branch block, premature ventricular complexes, or paced rhythms (f-pQRS) signify myocardial scar and higher mortality...
  23. doi request reprint Fragmented QRS on twelve-lead electrocardiogram predicts arrhythmic events in patients with ischemic and nonischemic cardiomyopathy
    Mithilesh Kumar Das
    Krannert Institute of Cardiology and Roudebush VA Medical Center, Indianapolis, Indiana, USA
    Heart Rhythm 7:74-80. 2010
    ..Fragmented QRS (fQRS) on 12-lead ECG represents myocardial conduction delays due to myocardial scar in patients with coronary artery disease (CAD)...
  24. ncbi request reprint Treating postprandial hyperglycemia does not appear to delay progression of early type 2 diabetes: the Early Diabetes Intervention Program
    M Sue Kirkman
    Indiana University School of Medicine, 545 Barnhill Dr, EH 421, Indianapolis, IN 46202, USA
    Diabetes Care 29:2095-101. 2006
    ....
  25. doi request reprint Usefulness of fragmented QRS on a 12-lead electrocardiogram in acute coronary syndrome for predicting mortality
    Mithilesh K Das
    Krannert Institute of Cardiology, Indiana University School of Medicine, Indianapolis, IN, USA
    Am J Cardiol 104:1631-7. 2009
    ..In conclusion, fQRS on 12-lead electrocardiography is a moderately sensitive but highly specific sign for ST elevation MI and NSTEMI. Fragmented QRS is an independent predictor of mortality in patients with ACS...
  26. ncbi request reprint A systems biology approach to the study of cisplatin drug resistance in ovarian cancers
    Jake Y Chen
    Indiana University School of Informatics, Department of Computer and Information Science, Purdue University School of Science, Indianapolis, IN 46202, USA
    J Bioinform Comput Biol 5:383-405. 2007
    ....
  27. doi request reprint Developing DCE-CT to quantify intra-tumor heterogeneity in breast tumors with differing angiogenic phenotype
    Minsong Cao
    School of Health Sciences, Purdue University, West Lafayette, IN 47907, USA
    IEEE Trans Med Imaging 28:861-71. 2009
    ..Monitoring variations in the tumor environment using DCE-CT offers an in vivo tool for the evaluation and optimization of new therapeutic strategies...
  28. pmc Severe impairment of endothelial function with the HIV-1 protease inhibitor indinavir is not mediated by insulin resistance in healthy subjects
    Michael P Dube
    Department of Medicine and the Division of Infectious Diseases, Indiana University School of Medicine, Wishard Memorial Hospital, 1001 W 10th Street, Suite OPW 430, Indianapolis, IN 46202, USA
    Cardiovasc Toxicol 8:15-22. 2008
    ..This suggests that indinavir's effects on glucose metabolism are not directly related to indinavir-associated endothelial dysfunction. Studies of the vascular effects of newer protease inhibitors are needed...
  29. ncbi request reprint Does age at diabetes diagnosis influence long-term physical and behavioral outcomes?
    Aaron E Carroll
    Department of Children s Health Services Research, Indiana University, Indianapolis, Indiana, USA
    Diabetes Care 30:2859-60. 2007
  30. doi request reprint Mechanisms of primary operative failure and results of remedial operation in patients with chronic pancreatitis
    Thomas J Howard
    Department of Surgery and Division of Biostatistics, Indiana University School of Medicine, Indianapolis, IN, USA
    J Gastrointest Surg 12:2087-95; discussion 2095-6. 2008
    ..Resection and drainage operations achieve long-term pain relief in approximately 85% of patients with chronic pancreatitis (CP). In patients who develop recurrent pain, a few data exist on the long-term results of remedial operations...
  31. pmc Continuous low-level vagus nerve stimulation reduces stellate ganglion nerve activity and paroxysmal atrial tachyarrhythmias in ambulatory canines
    Mark J Shen
    Krannert Institute of Cardiology, Division of Cardiology, Indiana University School of Medicine, Indianapolis, IN, USA
    Circulation 123:2204-12. 2011
    ..We hypothesize that left-sided low-level vagus nerve stimulation (LL-VNS) can suppress sympathetic outflow and reduce atrial tachyarrhythmias in ambulatory dogs...
  32. pmc Small-conductance calcium-activated potassium channel and recurrent ventricular fibrillation in failing rabbit ventricles
    Su Kiat Chua
    Krannert Institute of Cardiology, Division of Cardiology, Indiana University School of Medicine, Indianapolis, USA
    Circ Res 108:971-9. 2011
    ..Fibrillation/defibrillation episodes in failing ventricles may be followed by action potential duration (APD) shortening and recurrent spontaneous ventricular fibrillation (SVF)...
  33. doi request reprint Increased mortality with left ventricular systolic dysfunction and heart failure in adults with myotonic dystrophy type 1
    Deepak Bhakta
    Department of Medicine, Division Krannert Institute of Cardiology, Indiana University, Indianapolis, IN 46202, USA
    Am Heart J 160:1137-41, 1141.e1. 2010
    ..We studied the prevalence of these conditions and associated findings in a large population with DM1...
  34. pmc Treatment benefit and treatment harm rate to characterize heterogeneity in treatment effect
    Changyu Shen
    Department of Biostatistics, Indiana University School of Medicine, Indianapolis, Indiana 46202, U S A
    Biometrics 69:724-31. 2013
    ..A simulation study is presented to assess the performance of the proposed method. ..
  35. pmc Low-level vagus nerve stimulation upregulates small conductance calcium-activated potassium channels in the stellate ganglion
    Mark J Shen
    Krannert Institute of Cardiology and Division of Cardiology, Department of Medicine, Indiana University School of Medicine, Indianapolis, Indiana
    Heart Rhythm 10:910-5. 2013
    ..Small conductance calcium-activated potassium (SK) channels are responsible for afterhyperpolarization that suppresses nerve discharges...
  36. pmc Short-Term Rationing of Combination Antiretroviral Therapy: Impact on Morbidity, Mortality, and Loss to Follow-Up in a Large HIV Treatment Program in Western Kenya
    April J Bell
    Indiana University School of Medicine, 1001 West 10th Street, OPW M200, Indianapolis, IN 46202, USA
    AIDS Res Treat 2012:814564. 2012
    ..92 95% CI 0.82-1.03). Conclusions. Rationing of cART, even for a relatively short period of six months, led to clinically adverse outcomes...
  37. pmc An empirical Bayes model using a competition score for metabolite identification in gas chromatography mass spectrometry
    Jaesik Jeong
    Department of Biostatistics, Indiana University, 410 West 10th Street, Indianapolis, IN 46202, USA
    BMC Bioinformatics 12:392. 2011
    ..The competition score allows the model to properly assess the evidence on the presence/absence status of a metabolite based on whether or not the metabolite is matched to some sample spectrum...
  38. doi request reprint Pacemaker and implantable cardioverter-defibrillator use in a US myotonic dystrophy type 1 population
    Deepak Bhakta
    Division of Cardiology, Department of Medicine, Krannert Institute of Cardiology Department of Biostatistics, Indiana University, Indianapolis, Indiana, USA
    J Cardiovasc Electrophysiol 22:1369-75. 2011
    ..We assessed implant rates, indications, characteristics, and outcomes in patients with the neuromuscular disease, myotonic dystrophy type 1 (DM1) receiving a pacemaker or an implantable cardioverter-defibrillator (ICD)...
  39. pmc Reduced renal function is associated with progression to AIDS but not with overall mortality in HIV-infected Kenyan adults not initially requiring combination antiretroviral therapy
    Samir K Gupta
    Division of Infectious Diseases, Indiana University School of Medicine, Indianapolis, IN, USA
    J Int AIDS Soc 14:31. 2011
    ..Renal disease has been identified as a risk factor for disease progression or death in some populations...
  40. pmc Impact of integrated family planning and HIV care services on contraceptive use and pregnancy outcomes: a retrospective cohort study
    Rose J Kosgei
    United States Agency for International Development Academic Model Providing Access to Healthcare Partnership, Eldoret, Kenya
    J Acquir Immune Defic Syndr 58:e121-6. 2011
    ..To determine the impact of routine care (RC) and integrated family planning (IFP) and HIV care service on family planning (FP) uptake and pregnancy outcomes...
  41. pmc A penalized mixture model approach in genotype/phenotype association analysis for quantitative phenotypes
    Lang Li
    Division of Biostatistics, Department of Medicine, School of Medicine, Indiana University, Indianapolis, IN
    Cancer Inform 9:93-103. 2010
    ..The power and recovery rate of the true partition for the mixture model approach are investigated in statistical simulation studies, where it outperforms another published method...
  42. ncbi request reprint A statistical framework to discover true associations from multiprotein complex pull-down proteomics data sets
    Changyu Shen
    Division of Biostatistics, Department of Medicine, Indiana University School of Medicine, Indianapolis, Indiana 46202, USA
    Proteins 64:436-43. 2006
    ..3%. Cross-examination of our results with protein complexes confirmed by various experimental techniques demonstrates that many true associations that cannot be identified by previous approach are identified by our method...
  43. pmc A phase 1 and pharmacodynamic study of decitabine in combination with carboplatin in patients with recurrent, platinum-resistant, epithelial ovarian cancer
    Fang Fang
    Medical Sciences Program, Indiana University School of Medicine, Indianapolis, IN 46202, USA
    Cancer 116:4043-53. 2010
    ....
  44. doi request reprint Epithelial-to-mesenchymal transition and ovarian tumor progression induced by tissue transglutaminase
    Minghai Shao
    Department of Medicine, Indiana University School of Medicine, Indianapolis, Indiana, USA
    Cancer Res 69:9192-201. 2009
    ..Highly expressed in ovarian tumors, TG2 promotes EMT and enhances ovarian tumor metastasis by activating oncogenic signaling...
  45. doi request reprint Inverse probability weighting for covariate adjustment in randomized studies
    Changyu Shen
    Department of Biostatistics, School of Medicine, Fairbanks School of Public Health, Indiana University, Indianapolis, IN 46202, U S A
    Stat Med 33:555-68. 2014
    ..Both theoretical and numerical properties of the estimation procedure are presented. Application of the proposed method to a real data example is presented. Copyright © 2013 John Wiley & Sons, Ltd. ..
  46. doi request reprint Linkage of patient records from disparate sources
    Xiaochun Li
    Division of Biostatistics, Indiana University School of Medicine, Indianapolis, USA
    Stat Methods Med Res 22:31-8. 2013
    ..However, the recent availability of generators of synthetic data with realistic characteristics renders such evaluations feasible...
  47. pmc Impact of APE1/Ref-1 redox inhibition on pancreatic tumor growth
    Melissa L Fishel
    Department of Pediatrics, Herman B Wells Center for Pediatric Research, Indiana University of School of Medicine, 980 W Walnut, R3 548, Indianapolis, IN 46202, USA
    Mol Cancer Ther 10:1698-708. 2011
    ..These data indicate that E3330, inhibitor of APE1/Ref-1, has potential in pancreatic cancer and clinical investigation of APE1/Ref-1 molecular target is warranted...
  48. pmc Using RNase sequence specificity to refine the identification of RNA-protein binding regions
    Xin Wang
    Division of Biostatistics Department of Medicine, Indiana University School of Medicine, Indianapolis, IN 46202, USA
    BMC Genomics 9:S17. 2008
    ..We present two regions to which multiple amplicons map as examples to demonstrate this approach...
  49. doi request reprint Task-shifting of antiretroviral delivery from health care workers to persons living with HIV/AIDS: clinical outcomes of a community-based program in Kenya
    Henry M Selke
    Department of Medicine, Indiana University School of Medicine, Indianapolis, IN, USA
    J Acquir Immune Defic Syndr 55:483-90. 2010
    ..To assess whether community-based care delivered by people living with HIV/AIDS (PLWAs) could replace clinic-based HIV care...
  50. ncbi request reprint Predictors of nursing facility admission: a 12-year epidemiological study in the United States
    Ashok J Bharucha
    Division of Geriatrics and Neuropsychiatry, Department of Psychiatry, School of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
    J Am Geriatr Soc 52:434-9. 2004
    ..To identify predictors of institutionalization in a community-based cohort of older adults...
  51. pmc Relationship of body composition, metabolic status, antiretroviral use, and HIV disease factors to endothelial dysfunction in HIV-infected subjects
    Michael P Dube
    Department of Medicine and the Divisions of Infectious Diseases, Indiana University School of Medicine, Indianapolis, Indiana, USA
    AIDS Res Hum Retroviruses 26:847-54. 2010
    ..A definitive association with measures of adiposity was not detected in multivariate analysis, suggesting that lipoatrophy may not be an important contributor to endothelial dysfunction in HIV-infected individuals on ART...
  52. pmc Apamin-sensitive potassium current modulates action potential duration restitution and arrhythmogenesis of failing rabbit ventricles
    Yu Cheng Hsieh
    Department of Medicine, Division of Cardiology, Krannert Institute of Cardiology, Indiana University School of Medicine, Indianapolis, IN 46202, USA
    Circ Arrhythm Electrophysiol 6:410-8. 2013
    ..Apamin-sensitive K currents (I(KAS)) are upregulated in heart failure. We hypothesize that apamin can flatten action potential duration restitution (APDR) curve and can reduce ventricular fibrillation duration in failing ventricles...
  53. doi request reprint Survival and CTG repeat expansion in adults with myotonic dystrophy type 1
    William J Groh
    Department of Medicine, Division Cardiology, Krannert Institute of Cardiology, Indiana University, 1800 North Capitol, Room E300C, Indianapolis, Indiana 46202, USA
    Muscle Nerve 43:648-51. 2011
    ..It is unknown whether an association exists between survival and CTG repeat expansion...
  54. pmc Creation and evaluation of EMR-based paper clinical summaries to support HIV-care in Uganda, Africa
    Martin C Were
    Regenstrief Institute, Inc, Indiana University School of Medicine, Indianapolis, IN, USA
    Int J Med Inform 79:90-6. 2010
    ..We set out to provide patient-specific Electronic Medical Record (EMR)-based clinical summaries for providers taking care of HIV-positive adult patients in the resource-limited setting of Mbarara, Uganda...
  55. doi request reprint The telomerase template antagonist GRN163L alters MDA-MB-231 breast cancer cell morphology, inhibits growth, and augments the effects of paclitaxel
    Erin M Goldblatt
    Department of Medical and Molecular Genetics, Indiana University School of Medicine, Indianapolis, IN 46202 5251, USA
    Mol Cancer Ther 8:2027-35. 2009
    ..These data support a rationale for potentially combining GRN163L with paclitaxel for the treatment of breast cancer in the clinical setting...
  56. ncbi request reprint Mild cognitive impairment, amnestic type: an epidemiologic study
    Mary Ganguli
    Division of Geriatrics and Neuropsychiatry, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA
    Neurology 63:115-21. 2004
    ..To estimate the prevalence and examine the course of mild cognitive impairment (MCI), amnestic type, using current criteria, within a representative community sample...
  57. ncbi request reprint Serum anticholinergic activity in a community-based sample of older adults: relationship with cognitive performance
    Benoit H Mulsant
    Department of Psychiatry, University of Pittsburgh School of Medicine, PA, USA
    Arch Gen Psychiatry 60:198-203. 2003
    ..To our knowledge, there has not yet been any systematic study of the prevalence of SAA and its effect on cognition in a community-based population...
  58. ncbi request reprint Alzheimer disease and mortality: a 15-year epidemiological study
    Mary Ganguli
    Department of Epidemiology, University of Pittsburgh Graduate School of Public Health, Pittsburgh, PA 15213 2593, USA
    Arch Neurol 62:779-84. 2005
    ..Alzheimer disease (AD) is considered a leading cause of death, but few studies have examined the contribution of AD to mortality based on follow-up of representative US cohorts...
  59. ncbi request reprint Functional transitions and active life expectancy associated with Alzheimer disease
    Hiroko H Dodge
    Department of Epidemiology, University of Pittsburgh Graduate School of Public Health, Pittsburgh, PA 15261, USA
    Arch Neurol 60:253-9. 2003
    ....