Tammy J Sajdyk

Summary

Affiliation: Indiana University
Country: USA

Publications

  1. ncbi request reprint Neuropeptide Y-Y2 receptors mediate anxiety in the amygdala
    Tammy J Sajdyk
    Indiana University Medical Center, Indianapolis, IN 46202, USA
    Pharmacol Biochem Behav 71:419-23. 2002
  2. ncbi request reprint Neuropeptide Y in the amygdala induces long-term resilience to stress-induced reductions in social responses but not hypothalamic-adrenal-pituitary axis activity or hyperthermia
    Tammy J Sajdyk
    Institute of Psychiatric Research, Department of Psychiatry, Indiana University School of Medicine, Indianapolis, Indiana 46202, USA
    J Neurosci 28:893-903. 2008
  3. ncbi request reprint Interactions between NPY and CRF in the amygdala to regulate emotionality
    Tammy J Sajdyk
    Department of Psychiatry, Indiana University Medical School, 791 Union Drive, Rm M119, Indianapolis, IN 46202, USA
    Neuropeptides 38:225-34. 2004
  4. ncbi request reprint The role of neuropeptide Y in the amygdala on corticotropin-releasing factor receptor-mediated behavioral stress responses in the rat
    Tammy J Sajdyk
    Department of Psychiatry, Indiana University School of Medicine, Institute of Psychiatric Research, Indianapolis, IN 46202, USA
    Stress 9:21-8. 2006
  5. ncbi request reprint From anxiety to autism: spectrum of abnormal social behaviors modeled by progressive disruption of inhibitory neuronal function in the basolateral amygdala in Wistar rats
    William A Truitt
    Department of Psychiatry, Indiana University School of Medicine, 1111 West 10th Street, Indianapolis, IN 4620, USA
    Psychopharmacology (Berl) 191:107-18. 2007
  6. pmc Angiotensin II's role in sodium lactate-induced panic-like responses in rats with repeated urocortin 1 injections into the basolateral amygdala: amygdalar angiotensin receptors and panic
    Philip L Johnson
    Department of Anatomy and Cell Biology, Indiana University School of Medicine, Indianapolis, IN, United States
    Prog Neuropsychopharmacol Biol Psychiatry 44:248-56. 2013
  7. doi request reprint Measurement of panic-like responses following intravenous infusion of sodium lactate in panic-prone rats
    Tammy J Sajdyk
    Indiana University Medical Center, Indianapolis, Indiana, USA
    Curr Protoc Neurosci . 2003
  8. pmc Neonatal amygdala lesions: co-occurring impact on social/fear-related behavior and cocaine sensitization in adult rats
    R Andrews Chambers
    Laboratory for Translational Neuroscience of Dual Diagnosis and Development, Institute of Psychiatric Research, Department of Psychiatry, Indiana University School of Medicine, Indianapolis, IN 46202, USA
    Behav Neurosci 121:1316-27. 2007
  9. ncbi request reprint Angiotensin-II is a putative neurotransmitter in lactate-induced panic-like responses in rats with disruption of GABAergic inhibition in the dorsomedial hypothalamus
    Anantha Shekhar
    Department of Psychiatry, Institute of Psychiatric Research, Indiana University School of Medicine, Indianapolis, Indiana 46202, USA
    J Neurosci 26:9205-15. 2006
  10. pmc NPY Y1 receptors differentially modulate GABAA and NMDA receptors via divergent signal-transduction pathways to reduce excitability of amygdala neurons
    Andrei I Molosh
    Department of Psychiatry, Institute of Psychiatric Research, Indiana University, Indianapolis, IN, USA
    Neuropsychopharmacology 38:1352-64. 2013

Research Grants

Detail Information

Publications13

  1. ncbi request reprint Neuropeptide Y-Y2 receptors mediate anxiety in the amygdala
    Tammy J Sajdyk
    Indiana University Medical Center, Indianapolis, IN 46202, USA
    Pharmacol Biochem Behav 71:419-23. 2002
    ..These findings support the hypothesis that Y2 receptors are involved in the regulation of the anxiety response...
  2. ncbi request reprint Neuropeptide Y in the amygdala induces long-term resilience to stress-induced reductions in social responses but not hypothalamic-adrenal-pituitary axis activity or hyperthermia
    Tammy J Sajdyk
    Institute of Psychiatric Research, Department of Psychiatry, Indiana University School of Medicine, Indianapolis, Indiana 46202, USA
    J Neurosci 28:893-903. 2008
    ..These studies suggest one putative physiologic mechanism underlying stress resilience and could identify novel targets for development of therapies that can augment the ability to cope with stress...
  3. ncbi request reprint Interactions between NPY and CRF in the amygdala to regulate emotionality
    Tammy J Sajdyk
    Department of Psychiatry, Indiana University Medical School, 791 Union Drive, Rm M119, Indianapolis, IN 46202, USA
    Neuropeptides 38:225-34. 2004
    ....
  4. ncbi request reprint The role of neuropeptide Y in the amygdala on corticotropin-releasing factor receptor-mediated behavioral stress responses in the rat
    Tammy J Sajdyk
    Department of Psychiatry, Indiana University School of Medicine, Institute of Psychiatric Research, Indianapolis, IN 46202, USA
    Stress 9:21-8. 2006
    ..These results provide further support that an interaction between NPY and CRF within the BLA may be critical for maintaining a normal homeostatic emotional state...
  5. ncbi request reprint From anxiety to autism: spectrum of abnormal social behaviors modeled by progressive disruption of inhibitory neuronal function in the basolateral amygdala in Wistar rats
    William A Truitt
    Department of Psychiatry, Indiana University School of Medicine, 1111 West 10th Street, Indianapolis, IN 4620, USA
    Psychopharmacology (Berl) 191:107-18. 2007
    ..Social behaviors are disrupted in several psychiatric disorders. The amygdala is a key brain region involved in social behaviors, and amygdala pathology has been implicated in disease states ranging from social anxiety disorder to autism...
  6. pmc Angiotensin II's role in sodium lactate-induced panic-like responses in rats with repeated urocortin 1 injections into the basolateral amygdala: amygdalar angiotensin receptors and panic
    Philip L Johnson
    Department of Anatomy and Cell Biology, Indiana University School of Medicine, Indianapolis, IN, United States
    Prog Neuropsychopharmacol Biol Psychiatry 44:248-56. 2013
    ..Overall these results are the first to implicate A-II and AT1rs as putative neurotransmitter-receptors in NaLac induced panic-like responses in UCN/BLA-primed rats...
  7. doi request reprint Measurement of panic-like responses following intravenous infusion of sodium lactate in panic-prone rats
    Tammy J Sajdyk
    Indiana University Medical Center, Indianapolis, Indiana, USA
    Curr Protoc Neurosci . 2003
    ..A clinically relevant test, the sodium lactate challenge, is utilized to assess parallels between the human condition and this rat model...
  8. pmc Neonatal amygdala lesions: co-occurring impact on social/fear-related behavior and cocaine sensitization in adult rats
    R Andrews Chambers
    Laboratory for Translational Neuroscience of Dual Diagnosis and Development, Institute of Psychiatric Research, Department of Psychiatry, Indiana University School of Medicine, Indianapolis, IN 46202, USA
    Behav Neurosci 121:1316-27. 2007
    ..NAMLs may provide models for understanding a shared neurobiological basis for and complex interactions among psychiatric symptoms, drug exposure history, and addiction vulnerability...
  9. ncbi request reprint Angiotensin-II is a putative neurotransmitter in lactate-induced panic-like responses in rats with disruption of GABAergic inhibition in the dorsomedial hypothalamus
    Anantha Shekhar
    Department of Psychiatry, Institute of Psychiatric Research, Indiana University School of Medicine, Indianapolis, Indiana 46202, USA
    J Neurosci 26:9205-15. 2006
    ..Thus, these results implicate A-II pathways and the A-II receptors in the hypothalamus as putative substrates for sodium lactate-induced panic-like responses in vulnerable subjects...
  10. pmc NPY Y1 receptors differentially modulate GABAA and NMDA receptors via divergent signal-transduction pathways to reduce excitability of amygdala neurons
    Andrei I Molosh
    Department of Psychiatry, Institute of Psychiatric Research, Indiana University, Indianapolis, IN, USA
    Neuropsychopharmacology 38:1352-64. 2013
    ..This multipathway regulation of NMDA- and GABAA-mediated currents may be important for NPY plasticity and stress resilience in the amygdala...
  11. ncbi request reprint The amygdala, panic disorder, and cardiovascular responses
    Anantha Shekhar
    Department of Psychiatry, Indiana University Medical Center, Indianapolis, Indiana 46202, USA
    Ann N Y Acad Sci 985:308-25. 2003
    ..These results suggest that the BLA has a significant role in regulating anxiety, autonomic responses, and the development of anxiety disorders...
  12. ncbi request reprint Stress and central Urocortin increase anxiety-like behavior in the social interaction test via the CRF1 receptor
    Donald R Gehlert
    Neuroscience Division DC0510, Lilly Research Laboratories, Eli Lilly and Company, Lilly Corporate Center, Indianapolis, IN 46285 0510, United States
    Eur J Pharmacol 509:145-53. 2005
    ..These results provide further support for the CRF1 receptor in anxiety-like behavior and suggest this pathway is quiescent in unstressed animals...
  13. ncbi request reprint Corticotrophin releasing factor-induced synaptic plasticity in the amygdala translates stress into emotional disorders
    Donald G Rainnie
    Department of Psychiatry and Center for Behavioral Neuroscience, Emory University, Atlanta, Georgia 30322, USA
    J Neurosci 24:3471-9. 2004
    ....

Research Grants1

  1. Role of Amygdalar CRF Receptors in Regulating Anxiety
    Tammy Sajdyk; Fiscal Year: 2005
    ..Thus, the study will provide a greater understanding of the underlying neurobiology of pathological anxiety, in particular panic disorder. ..