Research Topics
Species | Chandan SahaSummaryAffiliation: Indiana University Country: USA Publications
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Publications
Onset of overweight during childhood and adolescence in relation to race and sexChandan Saha
Department of Medicine, Indiana University, Indianapolis, Indiana 46202 5111, USA correction
J Clin Endocrinol Metab 90:2648-52. 2005..04). There was no sex difference. The time to overweight during childhood and adolescence varies by race, indicating the need for race-specific timing of interventions...
Individual and neighborhood-level factors in predicting asthmaChandan Saha
Department of Medicine, Indiana University Purdue University at Indianapolis, USA
Arch Pediatr Adolesc Med 159:759-63. 2005..To identify the neighborhood socioeconomic and housing factors at the census-block level and the sociodemographic factors at the individual level that are associated with the risk of asthma...
Cerebral palsy after perinatal arterial ischemic strokeMeredith R Golomb
Division of Pediatric Neurology, Indiana University School of Medicine, 575 West Drive, Indianapolis, IN 46202, USA
J Child Neurol 23:279-86. 2008..60; 95% CI, 2.28-72.92) and large-branch infarction (OR, 8.78; 95% CI, 2.18-43.67) were associated with cerebral palsy. These data will aid physicians in planning long-term rehabilitative care for children with perinatal stroke...
Anti-inflammatory treatment with pentoxifylline improves HIV-related endothelial dysfunction: a pilot studySamir K Gupta
Department of Medicine, Indiana Center for Vascular Biology and Medicine, Indiana University School of Medicine, Indianapolis, USA
AIDS 24:1377-80. 2010..Pentoxifylline may reverse HIV-related endothelial dysfunction by directly inhibiting the endothelial leukocyte adhesion pathway...
Ethnic differences in renal responses to furosemideTae Yon Chun
Department of Medicine, Indiana University School of Medicine, Indianapolis, IN, USA
Hypertension 52:241-8. 2008..An increase in vasopressin levels appeared to explain greater urine concentrations in black males but not black females...
Dialysis dose and the diagnosis of hypertension in hemodialysis patientsRajiv Agarwal
Division of Nephrology, Department of Medicine, Indiana University School of Medicine, Indianapolis, Indiana, USA
Blood Press Monit 12:281-7. 2007..Evidence for effect modification was tested for several plausible demographic, clinical and laboratory factors...
Treatment of hyperglycemia in ischemic stroke (THIS): a randomized pilot trialAskiel Bruno
Department of Neurology, Indiana University School of Medicine, Roudebush Veterans Affairs Medical Center, Indianapolis, IN 46202, USA
Stroke 39:384-9. 2008..Hyperglycemia may worsen brain injury during acute cerebral infarction. We tested the feasibility and tolerability of aggressive hyperglycemia correction with intravenous insulin compared with usual care during acute cerebral infarction...
Treatment outcomes of secondarily impetiginized pediatric atopic dermatitis lesions and the role of oral antibioticsJeffrey B Travers
Department of Dermatology, Indiana University School of Medicine, 550 N University Blvd, Suite 3240, Indianapolis, IN 46202, Indiana, USA
Pediatr Dermatol 29:289-96. 2012....
Percent change on the National Institutes of Health Stroke Scale: a useful acute stroke outcome measureAskiel Bruno
Department of Neurology, Indiana University School of Medicine, Indianapolis, Indiana, USA
J Stroke Cerebrovasc Dis 18:56-9. 2009..Changes in neurologic deficits might be useful outcome measures in acute stroke because they can measure within-subject changes on the entire spectrum of the scales starting at baseline...
Studies of an association in boys of blood pressure and the Y chromosomeR Ravi Shankar
Department of Pediatrics, Indiana University School of Medicine, Indianapolis, IN 46202, USA
Am J Hypertens 20:27-31. 2007..In the current study, we examined the association of a HindIII restriction site on the Y chromosome with BP in a cohort of young men...
Endothelial, inflammatory, coagulation, metabolic effects and safety of etravirine in HIV-uninfected volunteersSamir K Gupta
Division of Infectious Diseases, Indiana University School of Medicine, Indianapolis, USA
AIDS Patient Care STDS 25:327-31. 2011..ETR was generally well tolerated. Larger studies are warranted to confirm that ETR can be used safely as part of HIV postexposure prophylaxis regimens...
Using change in the National Institutes of Health Stroke Scale to measure treatment effect in acute stroke trialsAskiel Bruno
Department of Neurology, Indiana University School of Medicine, Indianapolis, IN 46202, USA
Stroke 37:920-1. 2006..Outcome measures in acute stroke trials are being refined. Changes in neurological deficits might be useful outcome measures because they can measure the entire spectrum of deficits...
A novel application of the Problem Areas in Diabetes (PAID) instrument to improve glycemic control and patient satisfactionApoorva Chawla
David G Marrero, J O Ritchey Professor of Medicine, Division of Endocrinology and Metabolism, Indiana University School of Medicine, 410 West 10th Street, Suite 1140, Indianapolis, IN 46202, USA
Diabetes Educ 36:337-44. 2010....
Accuracy and yield of ICD-9 codes for identifying children with ischemic strokeMeredith R Golomb
Division of Pediatric Neurology, Indiana University School of Medicine, Riley Hospital for Children Room 1757702 Barnhill Drive, Indianapolis, IN 46202, USA
Neurology 67:2053-5. 2006..Code accuracy ranged from 37 to 88%; each code missed more than half of AIS identified by the combined code search. Studies are needed to determine whether other local and national ICD-9 databases have similar limitations...
Synchronization of adolescent blood pressure and pubertal somatic growthWanzhu Tu
Department of Medicine, Indiana University School of Medicine, Indianapolis, Indiana 46202, USA
J Clin Endocrinol Metab 94:5019-22. 2009..Blood pressure (BP) and growth increase at an accelerated rate during puberty. The temporal relationship of the two events has not been well characterized...
The change in blood pressure during pubertal growthR Ravi Shankar
Department of Pediatrics, Indiana University School of Medicine, Indianapolis, Indiana 46202-5111, USA
J Clin Endocrinol Metab 90:163-7. 2005..In summary, PG was associated with profound increases in systolic BP. There were noticeably greater increments in males than in females consistent with the emergence of the well known sexual dimorphism in BP...
Feeding problems in children with neonatal arterial ischemic strokeMonica Barkat-Masih
Division of Pediatric Neurology, Department of Neurology, Indiana University School of Medicine, Indianapolis, Indiana 46202, USA
J Child Neurol 25:867-72. 2010..12-9.90) but did not predict speech delay (P = .97) or cerebral palsy (P = .70). Feeding problems are important sequelae of neonatal stroke, but neonatal feeding problems in this group do not predict speech delay or cerebral palsy...
Endothelial abnormalities in adolescents with type 1 diabetes: a biomarker for vascular sequelae?Linda A DiMeglio
Department of Pediatrics, Indiana University School of Medicine, Indianapolis, IN 46202 5225, USA
J Pediatr 157:540-6. 2010....
Relationship between daily dose of oral medications and idiosyncratic drug-induced liver injury: search for signalsCraig Lammert
Department of Medicine, Emory University School of Medicine, Atlanta, GA, USA
Hepatology 47:2003-9. 2008..03). CONCLUSION: These data suggest a relationship between daily doses of oral prescription medications and idiosyncratic DILI. More studies are needed to validate these observations and to explore their implications...
Effect of advanced access scheduling on processes and intermediate outcomes of diabetes care and utilizationUsha Subramanian
Roudebush VAMC, Indianapolis, IN, USA
J Gen Intern Med 24:327-33. 2009..The impact of open access (OA) scheduling on chronic disease care and outcomes has not been studied...
Association of cerebral palsy with other disabilities in children with perinatal arterial ischemic strokeMeredith R Golomb
Division of Pediatric Neurology, Department of Neurology, Indiana University School of Medicine, Indianapolis, Indiana 46202, USA
Pediatr Neurol 37:245-9. 2007..21-69.21) than children with delayed presentation. Children with cerebral palsy after perinatal stroke are likely to have an additional disability; those with neonatal presentation are more likely to have a severe disability...
Improvement in blood pressure with inhibition of the epithelial sodium channel in blacks with hypertensionChandan Saha
Department of Medicine, Indiana University School of Medicine, Indianapolis, IN, USA
Hypertension 46:481-7. 2005..In conclusion, treatment with either amiloride or spironolactone can provide an additional reduction in blood pressure in blacks already receiving conventional antihypertensive therapy...
Variability in the upper limit of normal for serum alanine aminotransferase levels: a statewide studyAnand Dutta
Division of Gastroenterology and Hepatology, Indiana University School of Medicine, Indianapolis, IN 46202, USA
Hepatology 50:1957-62. 2009..Alternatively, studies should be undertaken to identify outcome-based reference intervals for ALT...
Lower serum adiponectin levels in African-American boysMikako Degawa-Yamauchi
Division of Endocrinology and Metabolism, Department of Medicine, Indiana University School of Medicine, 541 North Clinical Drive, Indianapolis, IN 46202-5111, USA
Obes Res 11:1384-90. 2003..A lower adiponectin level in African-American boys may predispose this group to a greater risk of diabetes and cardiovascular disease...
A pilot randomized controlled trial of renal protection with pioglitazone in diabetic nephropathyRajiv Agarwal
Division of Nephrology, Department of Medicine, Indiana University School of Medicine, Indianapolis, Indiana, USA
Kidney Int 68:285-92. 2005..We hypothesized that PPAR-gamma-based antidiabetic therapy would result in greater reduction in proteinuria compared to sulfonylurea-based therapy...
Fragmented QRS on a 12-lead ECG: a predictor of mortality and cardiac events in patients with coronary artery diseaseMithilesh Kumar Das
Krannert Institute of Cardiology, Indiana University School of Medicine, Indianapolis, Indiana 46202, USA
Heart Rhythm 4:1385-92. 2007..Fragmented QRS (fQRS) on a 12-lead electrocardiogram (ECG) is associated with myocardial scar in patients with coronary artery disease (CAD)...
Naltrexone and brief counseling to reduce heavy drinking in hazardous drinkersDena Davidson
Department of Psychiatry, School of Medicine, Institute of Psychiatric Research, Indiana University, 791 Union Drive Indianapolis 46202 4887, USA
Addict Behav 29:1253-8. 2004..Craving was also lower for the placebo group. The groups were not balanced on gender or family history of alcoholism and this may explain the lack of effect of naltrexone on the drinking outcomes...
Electrocardiographic abnormalities and sudden death in myotonic dystrophy type 1William J Groh
Department of Medicine, Krannert Institute of Cardiology, Indiana University, Indianapolis 46202, USA
N Engl J Med 358:2688-97. 2008..Sudden death can occur as a consequence of cardiac-conduction abnormalities in the neuromuscular disease myotonic dystrophy type 1. The determinants of the risk of sudden death remain imprecise...
Long-term effects of a community-based lifestyle intervention to prevent type 2 diabetes: the DEPLOY extension pilot studyRonald T Ackermann
Department of Medicine, Indiana University School of Medicine, Indianapolis, IN 46202, USA
Chronic Illn 7:279-90. 2011..We evaluated long-term effects of a lower cost, group-based adaption of the DPP lifestyle intervention offered by the YMCA...
Neuropsychologic outcomes in a case series of twins discordant for perinatal strokeTasneem L Talib
Division of Pediatric Neurology, Department of Neurology, Roudebush Veterans Affairs Medical Center Health Services, Indiana University School of Medicine, Indianapolis, Indiana 46202, USA
Pediatr Neurol 38:118-25. 2008..Twin gestation may be a risk factor for poor cognitive outcome after perinatal stroke. Large infarct size and comorbid epilepsy may have contributed to some of the poor cognitive outcomes in this cohort...
ASKing the kids: how children view their abilities after perinatal strokeMonica Barkat-Masih
Department of Neurology, Indiana University School of Medicine, Indianapolis, IN, USA
J Child Neurol 26:44-8. 2011..02), and children with large versus small branch unilateral middle cerebral artery stroke (P = .03). Further work is needed to understand why these children's performance does not match perceived capability...
Feasibility study of erythrocyte long-chain omega-3 polyunsaturated fatty acid content and mortality risk in hemodialysis patientsAllon N Friedman
Division of Nephrology, Indiana University School of Medicine, Indianapolis, Indiana 46202, USA
J Ren Nutr 18:509-12. 2008..We tested the hypothesis that erythrocyte n-3 PUFA levels, as measured by the omega-3 index (O3I), are inversely related to mortality in hemodialysis patients...
Are there ethnicity-based differences in the evaluation of individuals with abnormal liver biochemistries?Naga Chalasani
Department of Medicine, Indiana University School of Medicine, USA
J Hepatol 47:123-7. 2007..This study examined if there is an ethnicity-based difference in obtaining liver biochemistries or evaluating abnormal liver biochemistries by primary care physicians...
Out-of-hemodialysis-unit blood pressure is a superior determinant of left ventricular hypertrophyRajiv Agarwal
Division of Nephrology, Department of Medicine, Indiana University School of Medicine, Indianapolis, IN, USA
Hypertension 47:62-8. 2006..Routine and standardized measurements of BP were similarly weak correlates of LVH. Systolic BP outside the dialysis unit was a stronger correlate of LVH compared with dialysis unit BP...
Improvement in HIV-related endothelial dysfunction using the anti-inflammatory agent salsalate: a pilot studySamir K Gupta
Indiana University School of Medicine, Indianapolis, Indiana, USA
AIDS 22:653-5. 2008..However, hepatotoxicity occurred frequently. Research using alternative agents is warranted to examine the role of inflammation in HIV-related cardiovascular disease...
Research to Encourage Exercise for Fibromyalgia (REEF): use of motivational interviewing design and methodDennis C Ang
Division of Rheumatology, Department of Medicine, Indiana University, Indianapolis, IN 46202, United States
Contemp Clin Trials 32:59-68. 2011..When completed, REEF will determine whether exercise-based MI could be utilized as a management strategy to sustain the clinical benefits of exercise for FM...
Family history is a poor screen for prothrombotic genes in children with strokeSheila C Johal
Department of Medical Genetics, Division of Biostatistics, Indiana University School of Medicine, Indianapolis, Indiana 46202, USA
J Pediatr 148:68-71. 2006..To evaluate family history of early pathological thrombosis as a screen for genetic prothrombotic risk factors in children with stroke...
Infected atopic dermatitis lesions contain pharmacologic amounts of lipoteichoic acidJeffrey B Travers
Department of Dermatology, Indiana University School of Medicine, 702 Barnhill Drive, Indianapolis, IN 46202, USA
J Allergy Clin Immunol 125:146-52.e1-2. 2010..Bacterial infection with Staphylococcus aureus is a known trigger for worsening of atopic dermatitis (AD); the exact mechanisms by which bacterial infection worsens dermatitis are unknown...
IV insulin during acute cerebral infarction in diabetic patientsAskiel Bruno
Department of Neurology, Indiana University School of Medicine, Indianapolis, IN 46202-5111, USA
Neurology 62:1441-2. 2004
Utility of HbA1c in the detection of subclinical post renal transplant diabetesRebecca Hoban
Department of Surgery, Indiana University School of Medicine, Indianapolis, IN 46202, USA
Transplantation 81:379-83. 2006..1% of all patients and 19.4% of blacks found to have an elevated HbA1c. HbA1c testing should be considered as a screening test for PTDM, especially in African Americans...
A double-blind randomized crossover trial of two loop diuretics in chronic kidney diseaseNina Vasavada
Division of Nephrology, Department of Medicine, Indiana University School of Medicine, and Richard L. Roudebush VA Medical Center, Indianapolis, Indiana 46202, USA
Kidney Int 64:632-40. 2003....
Oral fish oil supplementation raises blood omega-3 levels and lowers C-reactive protein in haemodialysis patients--a pilot studyAkber Saifullah
Division of Nephrology, Indiana University School of Medicine, Indianapolis IN, USA
Nephrol Dial Transplant 22:3561-7. 2007....
Comparison of health and effective functioning in Russia and the United StatesGerald J Jogerst
Department of Family Medicine, 01290 G PFP, University of Iowa, 200 Hawkins Drive, Iowa City, IA 52242, USA
Clin Interv Aging 1:189-96. 2006..Global aging may increase the societal burden of providing more resources to augment elders' disabilities. The implications of functional disabilities can vary depending on the society in which they occur...
