Peter Roach

Summary

Affiliation: Indiana University
Country: USA

Publications

  1. Roach P, DePaoli Roach A, Hurley T, Tagliabracci V. Glycogen and its metabolism: some new developments and old themes. Biochem J. 2012;441:763-87 pubmed publisher
  2. request reprint
    Roach P. Glycogen and its metabolism. Curr Mol Med. 2002;2:101-20 pubmed
    ..Defects in the basic metabolizing enzymes lead to severe consequences whereas, with some exceptions, mutations in the regulatory proteins appear to cause a more subtle phenotypic change. ..
  3. Roach P. AMPK -> ULK1 -> autophagy. Mol Cell Biol. 2011;31:3082-4 pubmed publisher
  4. Roach P. Are there errors in glycogen biosynthesis and is laforin a repair enzyme?. FEBS Lett. 2011;585:3216-8 pubmed publisher
    ..The hypothesis is that glycogen phosphorylation can be considered a catalytic error and laforin a repair enzyme. ..
  5. Irimia J, Meyer C, Segvich D, Surendran S, DePaoli Roach A, Morral N, et al. Lack of liver glycogen causes hepatic insulin resistance and steatosis in mice. J Biol Chem. 2017;292:10455-10464 pubmed publisher
    ..Our results suggest that loss of liver glycogen synthesis diverts glucose toward fat synthesis, correlating with impaired hepatic insulin signaling and glucose disposal. ..