David E Nelson

Summary

Affiliation: Indiana University
Country: USA

Publications

  1. ncbi Chlamydial IFN-gamma immune evasion is linked to host infection tropism
    David E Nelson
    Laboratory of Intracellular Parasites, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Disease, National Institutes of Health, Hamilton, MT 59840, USA
    Proc Natl Acad Sci U S A 102:10658-63. 2005
  2. ncbi Bacterial communities of the coronal sulcus and distal urethra of adolescent males
    David E Nelson
    Department of Biology, Indiana University, Bloomington, Indiana, United States of America
    PLoS ONE 7:e36298. 2012
  3. ncbi Characteristic male urine microbiomes associate with asymptomatic sexually transmitted infection
    David E Nelson
    Department of Biology, Indiana University, Bloomington, Indiana, USA
    PLoS ONE 5:e14116. 2010
  4. ncbi Phenotypic rescue of Chlamydia trachomatis growth in IFN-gamma treated mouse cells by irradiated Chlamydia muridarum
    David E Nelson
    Department of Biology, Indiana University, Bloomington, IN 47405, USA
    Cell Microbiol 9:2289-98. 2007
  5. ncbi The microbial communities in male first catch urine are highly similar to those in paired urethral swab specimens
    Qunfeng Dong
    Department of Biology, University of North Texas, Denton, Texas, United States of America
    PLoS ONE 6:e19709. 2011
  6. ncbi Embryo fossilization is a biological process mediated by microbial biofilms
    Elizabeth C Raff
    Department of Biology and Indiana Molecular Biology Institute, Indiana University, Bloomington, IN 47405, USA
    Proc Natl Acad Sci U S A 105:19360-5. 2008
  7. ncbi Identification of Chlamydia trachomatis outer membrane complex proteins by differential proteomics
    Xiaoyun Liu
    Department of Biology, Indiana University, Bloomington, IN 47405, USA
    J Bacteriol 192:2852-60. 2010
  8. ncbi Pathogenic diversity among Chlamydia trachomatis ocular strains in nonhuman primates is affected by subtle genomic variations
    Laszlo Kari
    Laboratory of Intracellular Parasites, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, MT 59840, USA
    J Infect Dis 197:449-56. 2008
  9. ncbi Transcriptome analysis of chlamydial growth during IFN-gamma-mediated persistence and reactivation
    Robert J Belland
    Laboratories of Intracellular Parasites and Human Bacterial Pathogenesis, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, MT 59840, USA
    Proc Natl Acad Sci U S A 100:15971-6. 2003
  10. ncbi Chlamydial interferon gamma immune evasion influences infection tropism
    Grant McClarty
    Department of Medical Microbiology, University of Manitoba, Winnipeg, Manitoba, Canada
    Curr Opin Microbiol 10:47-51. 2007

Collaborators

Detail Information

Publications12

  1. ncbi Chlamydial IFN-gamma immune evasion is linked to host infection tropism
    David E Nelson
    Laboratory of Intracellular Parasites, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Disease, National Institutes of Health, Hamilton, MT 59840, USA
    Proc Natl Acad Sci U S A 102:10658-63. 2005
    ..Collectively, our findings show chlamydial host infection tropism is determined by IFN-gamma-mediated immunity...
  2. ncbi Bacterial communities of the coronal sulcus and distal urethra of adolescent males
    David E Nelson
    Department of Biology, Indiana University, Bloomington, Indiana, United States of America
    PLoS ONE 7:e36298. 2012
    ..Finally, our results suggest that the penis and the urethra can be colonized by a variety of BV-associated taxa and that some of these colonizations result from partnered sexual activity...
  3. ncbi Characteristic male urine microbiomes associate with asymptomatic sexually transmitted infection
    David E Nelson
    Department of Biology, Indiana University, Bloomington, Indiana, USA
    PLoS ONE 5:e14116. 2010
    ....
  4. ncbi Phenotypic rescue of Chlamydia trachomatis growth in IFN-gamma treated mouse cells by irradiated Chlamydia muridarum
    David E Nelson
    Department of Biology, Indiana University, Bloomington, IN 47405, USA
    Cell Microbiol 9:2289-98. 2007
    ..Chlamydial phenotypic rescue may have broader utility for the study of other EB associated virulence factors that function early in the interaction of chlamydiae with host cells...
  5. ncbi The microbial communities in male first catch urine are highly similar to those in paired urethral swab specimens
    Qunfeng Dong
    Department of Biology, University of North Texas, Denton, Texas, United States of America
    PLoS ONE 6:e19709. 2011
    ..Thus, urine can be used to characterize urethral microbiomes when swabs are undesirable, such as in population-based studies of the urethral microbiome or where multiple sampling of participants is required...
  6. ncbi Embryo fossilization is a biological process mediated by microbial biofilms
    Elizabeth C Raff
    Department of Biology and Indiana Molecular Biology Institute, Indiana University, Bloomington, IN 47405, USA
    Proc Natl Acad Sci U S A 105:19360-5. 2008
    ....
  7. ncbi Identification of Chlamydia trachomatis outer membrane complex proteins by differential proteomics
    Xiaoyun Liu
    Department of Biology, Indiana University, Bloomington, IN 47405, USA
    J Bacteriol 192:2852-60. 2010
    ..The list of COMC proteins identified in this study has provided reliable information for further understanding chlamydial protein secretion systems and modeling COMC and EB structures...
  8. ncbi Pathogenic diversity among Chlamydia trachomatis ocular strains in nonhuman primates is affected by subtle genomic variations
    Laszlo Kari
    Laboratory of Intracellular Parasites, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, MT 59840, USA
    J Infect Dis 197:449-56. 2008
    ..Our findings are the first to identify genes that correlate with differences in pathogenicity among trachoma strains...
  9. ncbi Transcriptome analysis of chlamydial growth during IFN-gamma-mediated persistence and reactivation
    Robert J Belland
    Laboratories of Intracellular Parasites and Human Bacterial Pathogenesis, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, MT 59840, USA
    Proc Natl Acad Sci U S A 100:15971-6. 2003
    ..In contrast to the paradigm of persistence as a general stress response, our findings suggest that persistence is an alternative life cycle used by chlamydiae to avoid the host immune response...
  10. ncbi Chlamydial interferon gamma immune evasion influences infection tropism
    Grant McClarty
    Department of Medical Microbiology, University of Manitoba, Winnipeg, Manitoba, Canada
    Curr Opin Microbiol 10:47-51. 2007
    ..These findings have important implications for chlamydial animal modeling studies...
  11. ncbi Inhibition of chlamydiae by primary alcohols correlates with the strain-specific complement of plasticity zone phospholipase D genes
    David E Nelson
    Laboratory of Intracellular Parasites, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Disease, National Institutes of Health, 903 South 4th Street, Hamilton, MT 59840, USA
    Infect Immun 74:73-80. 2006
    ..This inhibitory effect is amplified approximately 5,000-fold during recovery from persistent infection. These findings suggest that the chlamydial pzPLD may be important, strain-specific, pathogenesis factors in vivo...
  12. ncbi Chlamydial infection induces pathobiotype-specific protein tyrosine phosphorylation in epithelial cells
    Dezso P Virok
    Laboratory of Intracellular Parasites, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, NIH, 903 South 4th St, Hamilton, MT 59840, USA
    Infect Immun 73:1939-46. 2005
    ..If our hypothesis is correct, these heretofore-uncharacterized proteins may represent a novel class of bacterial molecules that influence pathogen-host range or tissue tropism...