Research Topics
| Jean P MollestonSummaryAffiliation: Indiana University Country: USA Publications
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Detail Information
Publications
Characteristics of idiosyncratic drug-induced liver injury in children: results from the DILIN prospective studyJean P Molleston
Indiana University School of Medicine, Indianapolis, IN, USA
J Pediatr Gastroenterol Nutr 53:182-9. 2011..The spectrum and severity of idiosyncratic drug-induced liver injury (DILI) in children are not well established...
Non-ABC acute hepatic failure associated with aplastic anemia can be treated with immunosuppressionJean P Molleston
Division of Pediatric Gastroenterology, Hepatology, and Nutrition, Indiana University School of Medicine, James Whitcomb Riley Hospital for Children, Indianapolis 46202, USA
J Pediatr Gastroenterol Nutr 46:216-9. 2008
Variceal bleeding in childrenJean Pappas Molleston
Indiana University School of Medicine, James Whitcomb Riley Hospital for Children, Division of Pediatric Gastroenterology, Hepatology and Nutrition, Indianapolis 46202, USA
J Pediatr Gastroenterol Nutr 37:538-45. 2003
A new review of portosystemic shunts in childrenJean Pappas Molleston
Clinical Pediatrics, James Whitcomb Riley Hospital for Children, USA
J Pediatr Gastroenterol Nutr 40:237-8. 2005
Exploring potential noninvasive biomarkers in eosinophilic esophagitis in childrenGirish Subbarao
Division of Pediatric Gastroenterology Hepatology Nutrition, Indiana University School of Medicine, Indianapolis, IN 46202, USA
J Pediatr Gastroenterol Nutr 53:651-8. 2011....
Pegylated interferon for chronic hepatitis C in children affects growth and body composition: results from the pediatric study of hepatitis C (PEDS-C) trialMaureen M Jonas
Division of Gastroenterology, Hepatology and Nutrition, Children s Hospital Boston, 300 Longwood Avenue, Boston, MA 02115, USA
Hepatology 56:523-31. 2012..These effects were generally reversible with cessation of therapy, although HAZ scores had not returned to baseline after 2 years of observation in many. Longer term growth data are needed among children treated for chronic HCV...
Accuracy and tolerability of the Bravo catheter-free pH capsule in patients between the ages of 4 and 18 yearsJoseph M Croffie
Section of Pediatric Gastroenterology, Hepatology and Nutrition, Indiana University School of Medicine, Indianapolis, IN 46202, USA
J Pediatr Gastroenterol Nutr 45:559-63. 2007..The aim of this study was to determine if the Bravo pH capsule is comparable to the nasally placed pH catheter in terms of pH-metry, safety, and tolerability in children...
Incidence, etiology, and risk factors for liver dysfunction in children following hematopoietic stem cell transplantationGirish Subbarao
Division of Pediatric Gastroenterology, Hepatology and Nutrition, Indiana University School of Medicine, Indianapolis, IN 46202 5225, USA
Pediatr Transplant 10:682-9. 2006..To identify risk factors which predispose children to develop liver dysfunction (LD) during the initial 100 days following hematopoietic stem cell transplantation (HSCT)...
Severe liver injury after initiating therapy with atomoxetine in two childrenJoel R Lim
Division of Pediatric Gastroenterology Hepatology Nutrition, James Whitcomb Riley Hospital for Children, Indiana University School of Medicine, Indianapolis 46202 5225, USA
J Pediatr 148:831-4. 2006..Atomoxetine may cause clinically significant hepatotoxicity either by metabolic idiosyncrasy or by inducing autoimmune hepatitis...
Nocturnal acid breakthrough in children with reflux esophagitis taking proton pump inhibitorsMarian D Pfefferkorn
Division of Pediatric Gastroenterology Hepatology Nutrition, Indiana University School of Medicine, James Whitcomb Riley Hospital for Children, 702 Barnhill Drive, Indianapolis, IN 46202, USA
J Pediatr Gastroenterol Nutr 42:160-5. 2006....
Lactase deficiency: not more common in pediatric patients with inflammatory bowel disease than in patients with chronic abdominal painMarian D Pfefferkorn
Division of Pediatric Gastroenterology Hepatology Nutrition, Indiana University School of Medicine, Indiana 46202, USA
J Pediatr Gastroenterol Nutr 35:339-43. 2002..Lactase deficiency is commonly found in adults with inflammatory bowel disease (IBD). Our aim was to determine its prevalence in children with IBD...
Comparison of serological markers of inflammatory bowel disease with clinical diagnosis in childrenSandeep K Gupta
Division of Pediatric Gastroenterology Hepatology Nutrition, James Whitcomb Riley Hospital for Children, Indiana University School of Medicine, Indianapolis, Indiana, USA
Inflamm Bowel Dis 10:240-4. 2004..Our purpose was to study the concordance of serological tests for inflammatory bowel disease with clinical diagnosis established by traditional testing in children...
Hepatic lipid peroxidation and cytochrome P-450 2E1 in pediatric nonalcoholic fatty liver disease and its subtypesLauren N Bell
Division of Gastroenterology Hepatology, Indiana University, Indianapolis, IN 46202, USA
J Clin Gastroenterol 45:800-7. 2011..To compare hepatic lipid peroxidation and cytochrome P-450 2E1 (CYP2E1) protein content in liver biopsies from children with nonalcoholic fatty liver disease (NAFLD) and 2 control groups...
White specks in the esophageal mucosa: An endoscopic manifestation of non-reflux eosinophilic esophagitis in childrenJoel R Lim
Division of Pediatric, Gastroenterology/Hepatology/Nutrition, Division of Pediatric Pathology, James Whitcomb Riley Hospital for Children, Indiana University School of Medicine, Indianapolis, Indiana 46202-5225, USA
Gastrointest Endosc 59:835-8. 2004..Eosinophilic esophagitis tends to be severe when white specks are present (> or =15 eosinophils/high power field) and is not associated with pathologic gastroesophageal reflux, as demonstrated by pH probe testing...
The role of esophagogastroduodenoscopy in the initial evaluation of childhood inflammatory bowel disease: a 7-year studyBisher A Abdullah
Division of Gastroenterology, James Whitcomb Riley Hospital for Children, Indiana University Medical Center, Indianapolis, USA
J Pediatr Gastroenterol Nutr 35:636-40. 2002..In some cases, granulomas were found solely in the upper gastrointestinal tracts. Based on our data, esophagogastroduodenoscopy with biopsy should be performed in all pediatric patients with suspected inflammatory bowel disease...
Effect of vitamin E or metformin for treatment of nonalcoholic fatty liver disease in children and adolescents: the TONIC randomized controlled trialJoel E Lavine
Department of Pediatrics, Division of Pediatric Gastroenterology, Hepatology, and Nutrition, Columbia University, New York, New York, USA
JAMA 305:1659-68. 2011..Nonalcoholic fatty liver disease (NAFLD) is the most common chronic liver disease in US children and adolescents and can present with advanced fibrosis or nonalcoholic steatohepatitis (NASH). No treatment has been established...
Hypoalbuminemia in a cystic fibrosis patient with severe erosive esophagitisMolly A Bozic
Division of Pediatric Gastroenterology, Hepatology, and Nutrition, James Whitcomb Riley Hospital for Children, Indiana University School of Medicine, 702 Barnhill Drive, Indianapolis, IN 46202 5225, USA
Nutr Clin Pract 25:304-7. 2010..Extensive evaluation failed to reveal a nutrition, pancreatic, intestinal, or renal explanation of his hypoalbuminemia. Identification and treatment of the esophagitis led to resolution of the hypoalbuminemia...
Comparison of oral prednisone and topical fluticasone in the treatment of eosinophilic esophagitis: a randomized trial in childrenElizabeth T Schaefer
Indiana University School of Medicine, James Whitcomb Riley Hospital for Children, Division of Pediatric Gastroenterology, Indianapolis, Indiana 46202, USA
Clin Gastroenterol Hepatol 6:165-73. 2008..We conducted a prospective randomized trial comparing oral prednisone (P) and swallowed fluticasone (F) for histologic and clinical response...
At what age is a suction rectal biopsy less likely to provide adequate tissue for identification of ganglion cells?Joseph M Croffie
Division of Pediatric Gastroenterology, Hepatology and Nutrition, Indiana University School of Medicine, James Whitcomb Riley Hospital for Children, Indianapolis 46202 5225, USA
J Pediatr Gastroenterol Nutr 44:198-202. 2007..The objective of this study was to determine at what age suction rectal biopsy is less likely to provide adequate tissue to detect submucosal ganglion cells in a child being evaluated for Hirschsprung disease...
Cysteinyl leukotriene levels in esophageal mucosal biopsies of children with eosinophilic inflammation: are they all the same?Sandeep K Gupta
Division of Pediatric Gastroenterology, James Whitcomb Riley Hospital for Children, Indiana University School of Medicine, Indianapolis 46202, USA
Am J Gastroenterol 101:1125-8. 2006..Cysteinyl leukotrienes (CysLT) are eosinophil chemoattractants. We studied CysLT levels in esophageal mucosa of children with AEE and controls...
Tacrolimus (FK506)-induced mutism after liver transplantDeborah K Sokol
Department of Neurology, Indiana University School of Medicine, Indianapolis, IN, USA
Pediatr Neurol 28:156-8. 2003..One year later, decreased fluency and mild ataxia persists. Rapid identification of speech loss linked to FK506 may be important because reduction or cessation of the drug may be associated with reverse of speech loss...
Assessment of the effectiveness of biofeedback in children with dyssynergic defecation and recalcitrant constipation/encopresis: does home biofeedback improve long-term outcomesJoseph M Croffie
Division of Pediatric Gastroenterology/Hepatology/Nutrition, James Whitcomb Riley Hospital for Children, Indiana University School of Medicine, Indianapolis, Indiana 46202-5225, USA
Clin Pediatr (Phila) 44:63-71. 2005..Biofeedback is beneficial for some children with chronic constipation and dyssynergic defecation. Supplemental home biofeedback does not improve long-term outcomes...
Obese children with steatohepatitis can develop cirrhosis in childhoodJean P Molleston
Division of Pediatric Gastroenterology/Hepatology/Nutrition, James Whitcomb Riley Hospital for Children, Indiana University School of Medicine, Indianapolis 46202-5225, USA
Am J Gastroenterol 97:2460-2. 2002..The two boys reported here developed cirrhosis from nonalcoholic steatohepatitis at ages 10 and 14 yr. One child progressed to cirrhosis with symptomatic portal hypertension within a 2-yr period...
