Raghavendra Mirmira

Summary

Affiliation: Indiana University
Country: USA

Publications

  1. pmc Translational control of inducible nitric oxide synthase by p38 MAPK in islet β-cells
    Yurika Nishiki
    Department of Pediatrics and the Herman B Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, Indiana 46202, USA
    Mol Endocrinol 27:336-49. 2013
  2. pmc Targeting regulatory T cells in the treatment of type 1 diabetes mellitus
    S M Cabrera
    Department of Pediatrics, and the Herman B Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, IN 46202, USA
    Curr Mol Med 12:1261-72. 2012
  3. pmc Islet β-cell endoplasmic reticulum stress precedes the onset of type 1 diabetes in the nonobese diabetic mouse model
    Sarah A Tersey
    Department of Pediatrics, Indiana University School of Medicine, Indianapolis, IN, USA
    Diabetes 61:818-27. 2012

Research Grants

Collaborators

  • Yurika Nishiki
  • Bernhard Maier
  • Andrew T Templin
  • Sarah A Tersey
  • S M Cabrera
  • Masayuki Hatanaka
  • Adeola Adewola
  • Stephanie C Colvin
  • Carmella Evans-Molina
  • Natalie D Stull
  • Jenna L Rickus
  • M R Rigby
  • Susanne M Cabrera

Detail Information

Publications3

  1. pmc Translational control of inducible nitric oxide synthase by p38 MAPK in islet β-cells
    Yurika Nishiki
    Department of Pediatrics and the Herman B Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, Indiana 46202, USA
    Mol Endocrinol 27:336-49. 2013
    ..Our results suggest a novel signaling pathway in β-cells in which p38 MAPK promotes translation elongation of Nos2 mRNA via regulation of eIF5A hypusination...
  2. pmc Targeting regulatory T cells in the treatment of type 1 diabetes mellitus
    S M Cabrera
    Department of Pediatrics, and the Herman B Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, IN 46202, USA
    Curr Mol Med 12:1261-72. 2012
    ..In this review, we summarize our current understanding of Treg function in health and in T1DM, and examine the effect of experimental therapies for T1DM on Treg cell number and function in both mice and humans...
  3. pmc Islet β-cell endoplasmic reticulum stress precedes the onset of type 1 diabetes in the nonobese diabetic mouse model
    Sarah A Tersey
    Department of Pediatrics, Indiana University School of Medicine, Indianapolis, IN, USA
    Diabetes 61:818-27. 2012
    ....

Research Grants11

  1. Chromatin Cofactors in Islet Development and Function
    Raghavendra G Mirmira; Fiscal Year: 2010
    ..Overall, this project seeks to understand how insulin-producing cells are formed and how specific genes might be used to reprogram other cell types to become insulin-producing cells for individuals with diabetes. ..
  2. Transcriptional Mechanisms Governing Beta Cell Differentiation
    Raghavendra Mirmira; Fiscal Year: 2007
    ..We believe that the proposed studies will provide the frameworkfor elucidating the molecular events governing b cell development and function ..
  3. Transcriptional Mechanisms Governing Beta Cell Differentiation
    Raghavendra Mirmira; Fiscal Year: 2007
    ..We believe that the proposed studies will provide the framework for elucidating the molecular events governing ¿ cell development and function. ..
  4. Mechanisms of Nkx6.1 Governing Beta-cell Differentiation
    Raghavendra Mirmira; Fiscal Year: 2006
    ..The studies proposed here will provide the framework for understanding the molecular events governing differentiation in the B-cell lineage, and can eventually be applied to engineering new B-cells for patients with diabetes. . ..
  5. Transcriptional Mechanisms Governing Beta Cell Differentiation
    Raghavendra G Mirmira; Fiscal Year: 2010
    ..We believe that the proposed studies will provide the framework for elucidating the molecular events governing cell development and function. ..