S A Mazzuca

Summary

Affiliation: Indiana University
Country: USA

Publications

  1. ncbi Malalignment and subchondral bone turnover in contralateral knees of overweight/obese women with unilateral osteoarthritis: implications for bilateral disease
    Steven A Mazzuca
    Indiana University School of Medicine, Indianapolis, USA
    Arthritis Care Res (Hoboken) 63:1528-34. 2011
  2. ncbi Subject retention and adherence in a randomized placebo-controlled trial of a disease-modifying osteoarthritis drug
    Steven A Mazzuca
    Indiana University School of Medicine, Indianapolis, 46202 5100, USA
    Arthritis Rheum 51:933-40. 2004
  3. ncbi Comparison of quantitative and semiquantitative indicators of joint space narrowing in subjects with knee osteoarthritis
    S A Mazzuca
    Department of Medicine, Indiana University School of Medicine, Indianapolis, 46202 5100, USA
    Ann Rheum Dis 65:64-8. 2006
  4. ncbi Severity of joint pain and Kellgren-Lawrence grade at baseline are better predictors of joint space narrowing than bone scintigraphy in obese women with knee osteoarthritis
    Steven A Mazzuca
    Department of Medicine, Indiana University School of Medicine IUSM, Indianapolis, 46202, USA
    J Rheumatol 32:1540-6. 2005
  5. ncbi Risk factors for progression of tibiofemoral osteoarthritis: an analysis based on fluoroscopically standardised knee radiography
    S A Mazzuca
    Indiana University School of Medicine, Department of Medicine, Rheumatology Division, Long Hospital Room 545, 1110 W Michigan St, Indianapolis, IN 46202 5100, USA
    Ann Rheum Dis 65:515-9. 2006
  6. ncbi Urinary levels of type II collagen C-telopeptide crosslink are unrelated to joint space narrowing in patients with knee osteoarthritis
    S A Mazzuca
    Indiana University School of Medicine, Department of Medicine, Rheumatology Division, Long Hospital Room 545, 1110 W Michigan St, Indianapolis, IN 46202 5100, USA
    Ann Rheum Dis 65:1055-9. 2006
  7. ncbi Associations between joint space narrowing and molecular markers of collagen and proteoglycan turnover in patients with knee osteoarthritis
    Steven A Mazzuca
    Department of Medicine, Indiana University School of Medicine, Indianapolis, USA
    J Rheumatol 33:1147-51. 2006
  8. ncbi Risk factors for early radiographic changes of tibiofemoral osteoarthritis
    Steven A Mazzuca
    Department of Medicine, Indiana University School of Medicine, Indianapolis, IN 46202 5100, USA
    Ann Rheum Dis 66:394-9. 2007
  9. ncbi Performance of a non-fluoroscopically assisted substitute for the Lyon schuss knee radiograph: quality and reproducibility of positioning and sensitivity to joint space narrowing in osteoarthritic knees
    S A Mazzuca
    Indiana University School of Medicine, Indianapolis, IN, USA
    Osteoarthritis Cartilage 16:1555-9. 2008
  10. ncbi Varus malalignment negates the structure-modifying benefits of doxycycline in obese women with knee osteoarthritis
    S A Mazzuca
    Indiana University School of Medicine, Indianapolis, IN, USA
    Osteoarthritis Cartilage 18:1008-11. 2010

Research Grants

  1. Markers of Progression of Knee Osteoarthritis
    STEVEN MAZZUCA; Fiscal Year: 2007

Detail Information

Publications31

  1. ncbi Malalignment and subchondral bone turnover in contralateral knees of overweight/obese women with unilateral osteoarthritis: implications for bilateral disease
    Steven A Mazzuca
    Indiana University School of Medicine, Indianapolis, USA
    Arthritis Care Res (Hoboken) 63:1528-34. 2011
    ....
  2. ncbi Subject retention and adherence in a randomized placebo-controlled trial of a disease-modifying osteoarthritis drug
    Steven A Mazzuca
    Indiana University School of Medicine, Indianapolis, 46202 5100, USA
    Arthritis Rheum 51:933-40. 2004
    ..To describe the methods by which remarkable levels of subject retention and adherence were achieved in a 30-month multicenter randomized placebo-controlled trial (RCT) of a disease-modifying osteoarthritis drug (DMOAD)...
  3. ncbi Comparison of quantitative and semiquantitative indicators of joint space narrowing in subjects with knee osteoarthritis
    S A Mazzuca
    Department of Medicine, Indiana University School of Medicine, Indianapolis, 46202 5100, USA
    Ann Rheum Dis 65:64-8. 2006
    ..To compare quantitative estimates of change in joint space width (JSW) with semiquantitative ratings of the progression of joint space narrowing (JSN) with respect to sensitivity to change over time...
  4. ncbi Severity of joint pain and Kellgren-Lawrence grade at baseline are better predictors of joint space narrowing than bone scintigraphy in obese women with knee osteoarthritis
    Steven A Mazzuca
    Department of Medicine, Indiana University School of Medicine IUSM, Indianapolis, 46202, USA
    J Rheumatol 32:1540-6. 2005
    ....
  5. ncbi Risk factors for progression of tibiofemoral osteoarthritis: an analysis based on fluoroscopically standardised knee radiography
    S A Mazzuca
    Indiana University School of Medicine, Department of Medicine, Rheumatology Division, Long Hospital Room 545, 1110 W Michigan St, Indianapolis, IN 46202 5100, USA
    Ann Rheum Dis 65:515-9. 2006
    ..To evaluate risk factors for progressive radiographic changes of knee osteoarthritis using a standardised fluoroscopically assisted protocol for knee radiography...
  6. ncbi Urinary levels of type II collagen C-telopeptide crosslink are unrelated to joint space narrowing in patients with knee osteoarthritis
    S A Mazzuca
    Indiana University School of Medicine, Department of Medicine, Rheumatology Division, Long Hospital Room 545, 1110 W Michigan St, Indianapolis, IN 46202 5100, USA
    Ann Rheum Dis 65:1055-9. 2006
    ..To determine whether urinary concentrations of the cross linked C-telopeptide of type II collagen (CTx-II) distinguish subjects with progressive radiographic or symptomatic knee osteoarthritis from those with stable disease...
  7. ncbi Associations between joint space narrowing and molecular markers of collagen and proteoglycan turnover in patients with knee osteoarthritis
    Steven A Mazzuca
    Department of Medicine, Indiana University School of Medicine, Indianapolis, USA
    J Rheumatol 33:1147-51. 2006
    ....
  8. ncbi Risk factors for early radiographic changes of tibiofemoral osteoarthritis
    Steven A Mazzuca
    Department of Medicine, Indiana University School of Medicine, Indianapolis, IN 46202 5100, USA
    Ann Rheum Dis 66:394-9. 2007
    ..To evaluate the risk factors for early radiographic changes of knee osteoarthritis...
  9. ncbi Performance of a non-fluoroscopically assisted substitute for the Lyon schuss knee radiograph: quality and reproducibility of positioning and sensitivity to joint space narrowing in osteoarthritic knees
    S A Mazzuca
    Indiana University School of Medicine, Indianapolis, IN, USA
    Osteoarthritis Cartilage 16:1555-9. 2008
    ....
  10. ncbi Varus malalignment negates the structure-modifying benefits of doxycycline in obese women with knee osteoarthritis
    S A Mazzuca
    Indiana University School of Medicine, Indianapolis, IN, USA
    Osteoarthritis Cartilage 18:1008-11. 2010
    ....
  11. ncbi Pilot study of the effects of a heat-retaining knee sleeve on joint pain, stiffness, and function in patients with knee osteoarthritis
    Steven A Mazzuca
    Indiana University School of Medicine, Indianapolis, IN 46202 5100, USA
    Arthritis Rheum 51:716-21. 2004
    ..To identify changes in joint pain, stiffness, and functional ability in patients with knee osteoarthritis (OA) after use of a knee sleeve that prevents loss of body heat by the joint...
  12. ncbi Pitfalls in the accurate measurement of joint space narrowing in semiflexed, anteroposterior radiographic imaging of the knee
    Steven A Mazzuca
    Department of Medicine, Indiana University, Indianapolis 46202 5100, USA
    Arthritis Rheum 50:2508-15. 2004
    ....
  13. ncbi Detection of radiographic joint space narrowing in subjects with knee osteoarthritis: longitudinal comparison of the metatarsophalangeal and semiflexed anteroposterior views
    Steven A Mazzuca
    Indiana University School of Medicine, Department of Medicine, Rheumatology Division, Long Hospital Room 545, 1110 West Michigan Street, Indianapolis, IN 46202 5100, USA
    Arthritis Rheum 48:385-90. 2003
    ..The present study was undertaken to compare the metatarsophalangeal (MTP) view and the semiflexed anteroposterior (AP) view with respect to sensitivity to JSN in knee OA...
  14. ncbi Knee pain reduces joint space width in conventional standing anteroposterior radiographs of osteoarthritic knees
    Steven A Mazzuca
    Department of Medicine, Rheumatology Division, Indiana University School of Medicine, Indianapolis 46202, USA
    Arthritis Rheum 46:1223-7. 2002
    ....
  15. ncbi Imaging and osteoarthritis: what is the predictive value?
    Steven A Mazzuca
    Rheumatology Division, Indiana University School of Medicine, Long Hospital Room 545, 1110 West Michigan Street, Indianapolis 46202, USA
    Curr Rheumatol Rep 5:27-32. 2003
    ....
  16. ncbi Development of radiographic changes of osteoarthritis in the "Chingford knee" reflects progression of disease or non-standardised positioning of the joint rather than incident disease
    S A Mazzuca
    Department of Medicine, Indiana University School of Medicine, USA
    Ann Rheum Dis 62:1061-5. 2003
    ....
  17. ncbi Field test of the reproducibility of the semiflexed metatarsophalangeal view in repeated radiographic examinations of subjects with osteoarthritis of the knee
    Steven A Mazzuca
    Indiana University School of Medicine, Department of Medicine, Indianapolis 46202 5100, USA
    Arthritis Rheum 46:109-13. 2002
    ....
  18. ncbi Is knee radiography useful for studying the efficacy of a disease-modifying osteoarthritis drug in humans?
    Steven A Mazzuca
    Division of Rheumatology, Department of Medicine, Indiana University School of Medicine, Long Hospital, Room 545, 1110 West Michigan Street, Indianapolis, IN 46202 5100, USA
    Rheum Dis Clin North Am 29:819-30. 2003
    ....
  19. ncbi Bone scintigraphy is not a better predictor of progression of knee osteoarthritis than Kellgren and Lawrence grade
    Steven A Mazzuca
    Department of Medicine, Department of Orthopaedic Surgery, Indiana University School of Medicine IUSM, Indianapolis, Indiana 46202 5100, USA
    J Rheumatol 31:329-32. 2004
    ....
  20. ncbi Acetaminophen, like conventional NSAIDs, may reduce synovitis in osteoarthritic knees
    Kenneth D Brandt
    Department of Medicine, Rheumatology Division, Indiana University School of Medicine, Indianapolis, IN 46202-5100, USA
    Rheumatology (Oxford) 45:1389-94. 2006
    ....
  21. ncbi Effect of alignment of the medial tibial plateau and x-ray beam on apparent progression of osteoarthritis in the standing anteroposterior knee radiograph
    S A Mazzuca
    Indiana University School of Medicine, Department of Medicine, Long Hospital, Indianapolis 46202-5100, USA
    Arthritis Rheum 44:1786-94. 2001
    ....
  22. ncbi Experience with a placebo-controlled randomized clinical trial of a disease-modifying drug for osteoarthritis: the doxycycline trial
    Kenneth D Brandt
    Department of Medicine, Indiana University School of Medicine, Indianapolis, IN 46202 5100, USA
    Rheum Dis Clin North Am 32:217-34, xi-xii. 2006
    ....
  23. ncbi Lessons learned from nine clinical trials of disease-modifying osteoarthritis drugs
    Kenneth D Brandt
    Rheumatology Division, Indiana University School of Medicine, 1110 West Michigan Street, Rm. LO 545, Indianapolis, IN 46202-5100, USA
    Arthritis Rheum 52:3349-59. 2005
  24. ncbi Effects of doxycycline on progression of osteoarthritis: results of a randomized, placebo-controlled, double-blind trial
    Kenneth D Brandt
    Indiana University School of Medicine, Rheumatology Division, Indianapolis, IN 46202 5100, USA
    Arthritis Rheum 52:2015-25. 2005
    ..To confirm preclinical data suggesting that doxycycline can slow the progression of osteoarthritis (OA). The primary outcome measure was joint space narrowing (JSN) in the medial tibiofemoral compartment...
  25. ncbi Which is the best radiographic protocol for a clinical trial of a structure modifying drug in patients with knee osteoarthritis?
    Kenneth D Brandt
    Rheumatology Division, Indiana University School of Medicine, Indianapolis 46202 5100, USA
    J Rheumatol 29:1308-20. 2002
  26. ncbi Effects of strength training on the incidence and progression of knee osteoarthritis
    Alan E Mikesky
    Indiana University-Purdue University, Indianapolis, IN, USA
    Arthritis Rheum 55:690-9. 2006
    ..CONCLUSION: The ST group retained more strength and exhibited less frequent progressive JSN over 30 months than the ROM group. The increase in incident JSN >0.50 mm in ST is unexplained and requires confirmation...
  27. ncbi Urinary TIINE concentrations in a randomized controlled trial of doxycycline in knee osteoarthritis: implications of the lack of association between TIINE levels and joint space narrowing
    Ivan G Otterness
    School of Pharmacy, University of Rhode Island, Kingston, Rhode Island, USA
    Arthritis Rheum 56:3644-9. 2007
    ....
  28. ncbi Use of the plasma stromelysin (matrix metalloproteinase 3) concentration to predict joint space narrowing in knee osteoarthritis
    L Stefan Lohmander
    Lund University, Lund, Sweden
    Arthritis Rheum 52:3160-7. 2005
    ..CONCLUSION: The baseline MMP-3 level was a significant predictor of JSN in this pilot study. Moreover, serial plasma MMP-3 levels reflected concurrent JSN in the placebo group over the 30-month period of observation...
  29. ncbi Measurement of radiographic joint space width in the tibiofemoral compartment of the osteoarthritic knee: comparison of standing anteroposterior and Lyon schuss views
    Eric Vignon
    Claude Bernard University, Lyon, France
    Arthritis Rheum 48:378-84. 2003
    ..To evaluate progression of joint space narrowing in radiographs of osteoarthritic (OA) knees imaged in both the standing anteroposterior (AP) and the Lyon schuss positions, using alternative methods to measure joint space width (JSW)...
  30. ncbi The randomized clinical trial of doxycycline in knee osteoarthritis: comment on the editorial by Dieppe
    Kenneth D Brandt
    Arthritis Rheum 54:684. 2006
  31. ncbi Arthritis, continuing medical education, and oil sand: changes in market forces can alter perceptions of an underutilized resource
    Steven A Mazzuca
    J Rheumatol 33:1721-2. 2006

Research Grants2

  1. Markers of Progression of Knee Osteoarthritis
    STEVEN MAZZUCA; Fiscal Year: 2007
    ....