Research Topics
| Mark W KimpelSummaryAffiliation: Indiana University Country: USA Publications
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Publications
Functional gene expression differences between inbred alcohol-preferring and -non-preferring rats in five brain regionsMark W Kimpel
Department of Psychiatry, Indiana University School of Medicine, Indianapolis, IN 46202 4887, USA
Alcohol 41:95-132. 2007..The many regional and overall gene expression differences between the iP and iNP rat lines may contribute to the divergent alcohol drinking phenotypes of these rats...
Gene expression changes in the nucleus accumbens of alcohol-preferring rats following chronic ethanol consumptionRichard L Bell
Department of Psychiatry, Indiana University Purdue University at Indianapolis, Indianapolis, IN 46202, USA
Pharmacol Biochem Behav 94:131-47. 2009..Conversely, chronic MSA drinking, with its associated protracted withdrawal periods, results in genomic changes that may be masked by tight regulation of these genes following repeated experiences of ethanol withdrawal...
Differential gene expression in the nucleus accumbens with ethanol self-administration in inbred alcohol-preferring ratsZachary A Rodd
Department of Psychiatry, Indiana University School of Medicine, Indianapolis, IN 46202 4887, United States
Pharmacol Biochem Behav 89:481-98. 2008..g., Cav2, Nrxn3, Gabrb2, Gad1, Homer1) and homeostasis (S100b, Prkca, Ftl1) categories. Overall, the results suggest that changes in gene expression in the ACB of iP rats are associated with the reinforcing effects of EtOH...
Candidate genes for alcohol preference identified by expression profiling in alcohol-preferring and -nonpreferring reciprocal congenic ratsTiebing Liang
Indiana University School of Medicine, Department of Medicine, IB424G, 975 West Walnut Street, Indianapolis, IN 46202, USA
Genome Biol 11:R11. 2010..NP congenic rats: amygdala, nucleus accumbens, hippocampus, caudate putamen, and frontal cortex...
Changes in gene expression in regions of the extended amygdala of alcohol-preferring rats after binge-like alcohol drinkingWilliam J McBride
Department of Psychiatry, Institute of Psychiatric Research, Indiana University Purdue University at Indianapolis, Indianapolis, 46202 4887, USA
Alcohol 44:171-83. 2010....
Fine mapping and expression of candidate genes within the chromosome 10 QTL region of the high and low alcohol-drinking ratsPaula J Bice
Department of Medicine, Indiana University School of Medicine, Medical Research and Library Building, Indianapolis, IN 46202, USA
Alcohol 44:477-85. 2010..All six genes showed differential expression in at least one brain region. Of the genes tested in this study, Crebbp and Mapk8ip3 may be the most promising candidates with regard to alcohol drinking...
Differential effects of ethanol in the nucleus accumbens shell of alcohol-preferring (P), alcohol-non-preferring (NP) and Wistar rats: a proteomics studyWilliam J McBride
Department of Psychiatry, Institute of Psychiatric Research, Indiana University School of Medicine, Indianapolis, IN 46202, United States
Pharmacol Biochem Behav 92:304-13. 2009....
Gene expression in the ventral tegmental area of 5 pairs of rat lines selectively bred for high or low ethanol consumptionWilliam J McBride
Institute of Psychiatric Research, Department of Psychiatry, Indiana University School of Medicine, Indianapolis, IN 46202 4887, USA
Pharmacol Biochem Behav 102:275-85. 2012....
Identification of candidate genes for alcohol preference by expression profiling of congenic rat strainsLucinda G Carr
Department of Medicine, Indiana University School of Medicine, Indianapolis, IN 46202, USA
Alcohol Clin Exp Res 31:1089-98. 2007..This study was undertaken to identify genes in the chromosome 4 QTL interval that might contribute to the differences in alcohol consumption between the alcohol-naïve congenic and background strains...
A proteomic survey of rat cerebral cortical synaptosomesFrank A Witzmann
Department of Cellular and Integrative Physiology, Indiana University School of Medicine, Indianapolis, 46202, USA
Proteomics 5:2177-201. 2005..The results also suggest that this experimental approach can be used to study the differential expression of multiple proteins involved in alterations of synaptic function...
Pain thresholds in alcohol preferring and non-preferring rats: diurnal and repeated trial line differencesMark W Kimpel
Department of Medicine, Indiana University School of Medicine, Indianapolis 46202, USA
Alcohol Clin Exp Res 27:1921-8. 2003..A novel finding of Decline in Latency with Repeated Trials (DLRT) was found in both alcohol preferring and nonpreferring lines; degree of DLRT differed as a function of line and circadian period...
