RAYMOND MORRIS JOHNSON

Summary

Affiliation: Indiana University
Country: USA

Publications

  1. pmc Perforin is detrimental to Controllinγ C. muridarum replication in vitro, but not in vivo
    Raymond M Johnson
    Department of Medicine, Indiana University School of Medicine, Indianapolis, Indiana, USA
    PLoS ONE 8:e63340. 2013
  2. pmc PmpG303-311, a protective vaccine epitope that elicits persistent cellular immune responses in Chlamydia muridarum-immune mice
    Raymond M Johnson
    Department of Medicine, Indiana University School of Medicine, Indianapolis, Indiana, USA
    Infect Immun 80:2204-11. 2012
  3. pmc Plac8-dependent and inducible NO synthase-dependent mechanisms clear Chlamydia muridarum infections from the genital tract
    Raymond M Johnson
    Department of Medicine, Indiana University School of Medicine, Indianapolis, IN 46202, USA
    J Immunol 188:1896-904. 2012
  4. ncbi request reprint Kawasaki-like syndromes and other vasculitic syndromes in HIV-infected patients
    Raymond M Johnson
    Division of Infectious Diseases, Indiana School of Medicine, Indianapolis, Indiana 46202, USA
    AIDS 17:S77-82. 2003
  5. ncbi request reprint Safety and tolerability of sequential pegylated IFN-alpha2a and tenofovir for hepatitis B infection in HIV(+) individuals
    R M Johnson
    Indiana University School of Medicine, Indianapolis, Indiana 46202, USA
    HIV Clin Trials 8:173-81. 2007
  6. pmc Murine oviduct epithelial cell cytokine responses to Chlamydia muridarum infection include interleukin-12-p70 secretion
    Raymond M Johnson
    Division of Infectious Diseases, Department of Medicine, Indiana University School of Medicine, 545 Barnhill Dr 435, Indianapolis, IN 46202, USA
    Infect Immun 72:3951-60. 2004
  7. pmc Anti-inflammatory treatment with pentoxifylline improves HIV-related endothelial dysfunction: a pilot study
    Samir K Gupta
    Department of Medicine, Indiana Center for Vascular Biology and Medicine, Indiana University School of Medicine, Indianapolis, USA
    AIDS 24:1377-80. 2010
  8. doi request reprint The Chlamydia muridarum-induced IFN-β response is TLR3-dependent in murine oviduct epithelial cells
    Wilbert A Derbigny
    Department of Microbiology and Immunology, Indiana University School of Medicine, Indianapolis, IN 46202, USA
    J Immunol 185:6689-97. 2010
  9. doi request reprint Improvement in HIV-related endothelial dysfunction using the anti-inflammatory agent salsalate: a pilot study
    Samir K Gupta
    Indiana University School of Medicine, Indianapolis, Indiana, USA
    AIDS 22:653-5. 2008
  10. pmc Chlamydia muridarum infection elicits a beta interferon response in murine oviduct epithelial cells dependent on interferon regulatory factor 3 and TRIF
    Wilbert A Derbigny
    Department of Medicine, Indiana University School of Medicine, Indianapolis, IN 46202, USA
    Infect Immun 75:1280-90. 2007

Research Grants

  1. Immunobiology of Chlamydia
    Raymond Johnson; Fiscal Year: 2004
  2. Cellular Immunity to Chlamydua at the Epithelial Interface
    Raymond Johnson; Fiscal Year: 2007
  3. Cellular Immunity to Chlamydua at the Epithelial Interface
    RAYMOND MORRIS JOHNSON; Fiscal Year: 2010
  4. Cellular Immunity to Chlamydua at the Epithelial Interface
    Raymond Johnson; Fiscal Year: 2009

Collaborators

Detail Information

Publications13

  1. pmc Perforin is detrimental to Controllinγ C. muridarum replication in vitro, but not in vivo
    Raymond M Johnson
    Department of Medicine, Indiana University School of Medicine, Indianapolis, Indiana, USA
    PLoS ONE 8:e63340. 2013
    ....
  2. pmc PmpG303-311, a protective vaccine epitope that elicits persistent cellular immune responses in Chlamydia muridarum-immune mice
    Raymond M Johnson
    Department of Medicine, Indiana University School of Medicine, Indianapolis, Indiana, USA
    Infect Immun 80:2204-11. 2012
    ....
  3. pmc Plac8-dependent and inducible NO synthase-dependent mechanisms clear Chlamydia muridarum infections from the genital tract
    Raymond M Johnson
    Department of Medicine, Indiana University School of Medicine, Indianapolis, IN 46202, USA
    J Immunol 188:1896-904. 2012
    ..Although T cell subsets are routinely defined by cytokine profiles, there may be important subdivisions by effector function, in this case CD4(Plac8)...
  4. ncbi request reprint Kawasaki-like syndromes and other vasculitic syndromes in HIV-infected patients
    Raymond M Johnson
    Division of Infectious Diseases, Indiana School of Medicine, Indianapolis, Indiana 46202, USA
    AIDS 17:S77-82. 2003
    ..Immunohistopathology of the affected arteries suggests that he died of a Kawasaki-like syndrome...
  5. ncbi request reprint Safety and tolerability of sequential pegylated IFN-alpha2a and tenofovir for hepatitis B infection in HIV(+) individuals
    R M Johnson
    Indiana University School of Medicine, Indianapolis, Indiana 46202, USA
    HIV Clin Trials 8:173-81. 2007
    ....
  6. pmc Murine oviduct epithelial cell cytokine responses to Chlamydia muridarum infection include interleukin-12-p70 secretion
    Raymond M Johnson
    Division of Infectious Diseases, Department of Medicine, Indiana University School of Medicine, 545 Barnhill Dr 435, Indianapolis, IN 46202, USA
    Infect Immun 72:3951-60. 2004
    ..Data from these in vitro studies predict that infected oviduct epithelium contributes significantly to host innate and adaptive defenses but may also participate in the immunopathology seen with Chlamydia infections...
  7. pmc Anti-inflammatory treatment with pentoxifylline improves HIV-related endothelial dysfunction: a pilot study
    Samir K Gupta
    Department of Medicine, Indiana Center for Vascular Biology and Medicine, Indiana University School of Medicine, Indianapolis, USA
    AIDS 24:1377-80. 2010
    ..Pentoxifylline may reverse HIV-related endothelial dysfunction by directly inhibiting the endothelial leukocyte adhesion pathway...
  8. doi request reprint The Chlamydia muridarum-induced IFN-β response is TLR3-dependent in murine oviduct epithelial cells
    Wilbert A Derbigny
    Department of Microbiology and Immunology, Indiana University School of Medicine, Indianapolis, IN 46202, USA
    J Immunol 185:6689-97. 2010
    ....
  9. doi request reprint Improvement in HIV-related endothelial dysfunction using the anti-inflammatory agent salsalate: a pilot study
    Samir K Gupta
    Indiana University School of Medicine, Indianapolis, Indiana, USA
    AIDS 22:653-5. 2008
    ..However, hepatotoxicity occurred frequently. Research using alternative agents is warranted to examine the role of inflammation in HIV-related cardiovascular disease...
  10. pmc Chlamydia muridarum infection elicits a beta interferon response in murine oviduct epithelial cells dependent on interferon regulatory factor 3 and TRIF
    Wilbert A Derbigny
    Department of Medicine, Indiana University School of Medicine, Indianapolis, IN 46202, USA
    Infect Immun 75:1280-90. 2007
    ..Antagonism of either IRF-3 or TRIF signaling significantly decreased IFN-beta production. These data implicate TLR3, or an unknown PRR utilizing TRIF, as the source of IFN-beta production by Chlamydia-infected oviduct epithelial cells...
  11. ncbi request reprint Pattern recognition molecules activated by Chlamydia muridarum infection of cloned murine oviduct epithelial cell lines
    Wilbert A Derbigny
    Department of Medicine, Indiana University School of Medicine, Indianapolis, IN 46202, USA
    J Immunol 175:6065-75. 2005
    ..muridarum-infected oviduct epithelial cell lines. The pattern recognition molecule responsible for infection-induced IFN-beta secretion by oviduct epithelial cells remains to be determined...
  12. pmc Chlamydia muridarum-specific CD4 T-cell clones recognize infected reproductive tract epithelial cells in an interferon-dependent fashion
    Krupakar Jayarapu
    Division of Infectious Diseases, Department of Medicine, Indiana University School of Medicine, 545 Barnhill Drive, 435, Indianapolis, IN 46202, USA
    Infect Immun 77:4469-79. 2009
    ..We discuss our data as they relate to published studies with IFN knockout mice, proposing a straightforward interpretation of the existing literature based on CD4 T-cell interactions with the infected reproductive tract epithelium...
  13. pmc Chlamydial IFN-gamma immune evasion is linked to host infection tropism
    David E Nelson
    Laboratory of Intracellular Parasites, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Disease, National Institutes of Health, Hamilton, MT 59840, USA
    Proc Natl Acad Sci U S A 102:10658-63. 2005
    ..Collectively, our findings show chlamydial host infection tropism is determined by IFN-gamma-mediated immunity...

Research Grants6

  1. Immunobiology of Chlamydia
    Raymond Johnson; Fiscal Year: 2004
    ..3) To determine the effect of adoptive transfer of mucosal CD8 and CD4 T lymphocytes on the natural course of MoPn genital tract infections. ..
  2. Cellular Immunity to Chlamydua at the Epithelial Interface
    Raymond Johnson; Fiscal Year: 2007
    ..Defining what protective T cells look like, and how they function, will be critical for designing and assessing future Chlamydia candidate vaccines. ..
  3. Cellular Immunity to Chlamydua at the Epithelial Interface
    RAYMOND MORRIS JOHNSON; Fiscal Year: 2010
    ..Defining what protective T cells look like, and how they function, will be critical for designing and assessing future Chlamydia candidate vaccines. ..
  4. Cellular Immunity to Chlamydua at the Epithelial Interface
    Raymond Johnson; Fiscal Year: 2009
    ..Defining what protective T cells look like, and how they function, will be critical for designing and assessing future Chlamydia candidate vaccines. ..