Research Topics
Species | H C HendrieSummaryAffiliation: Indiana University Country: USA Publications
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Detail Information
Publications
International studies in dementia with particular emphasis on populations of African originHugh C Hendrie
Department of Psychiatry, and Center for Aging Research, Indiana University School of Medicine, Indianapolis, IN 46202, USA
Alzheimer Dis Assoc Disord 20:S42-6. 2006..We eventually hope to create a risk factor model that will not only account for the dementia rate differences between Yoruba and African Americans, but also help explain dementia rates in other developing and developed countries...
Alzheimer's disease, genes, and environment: the value of international studiesHugh C Hendrie
Department of Psychiatry, Indiana University School of Medicine, Indiana University Center for Aging Research, Indianapolis 46202 2872, USA
Can J Psychiatry 49:92-9. 2004..To describe the construction of a disease model incorporating both genetic an environmental factors in the etiology of Alzheimer's disease (AD), using data generated from the Indianapolis-Ibadan dementia project (I-IDP)...
Incidence of dementia and Alzheimer disease in 2 communities: Yoruba residing in Ibadan, Nigeria, and African Americans residing in Indianapolis, IndianaH C Hendrie
Department of Psychiatry, Indiana University School of Medicine, 541 Clinical Dr, Room 394A, Indianapolis, IN 46202, USA
JAMA 285:739-47. 2001..If populations were identified with significantly lower or higher incidence rates of AD, the search for risk factors in the genesis of AD could be greatly enhanced...
Lessons learned from international comparative crosscultural studies on dementiaHugh C Hendrie
Department of Psychiatry, Indiana University School of Medicine, University Center for Aging Research, Indianapolis, Indiana, USA
Am J Geriatr Psychiatry 14:480-8. 2006....
The development of a semi-structured home interview (CHIF) to directly assess function in cognitively impaired elderly people in two culturesH C Hendrie
Department of Psychiatry, Indiana University School of Medicine, Indianapolis, IN 46202, USA
Int Psychogeriatr 18:653-66. 2006..Assessing function is a crucial element in the diagnosis of dementia. This information is usually obtained from key informants. However, reliable informants are not always available...
Estimating disease prevalence from two-phase surveys with non-response at the second phaseS Gao
Division of Biostatistics, Department of Medicine, Indiana University School of Medicine, Indianapolis, 46202 2872, USA
Stat Med 19:2101-14. 2000..These estimators are illustrated using data from an Alzheimer's disease study in two populations...
Estimating odds ratios adjusting for misclassification in Alzheimer's disease risk factor assessmentC L Emsley
Division of Biostatistics, Indiana University School of Medicine, RG 4th, 1001 West Tenth Street, Indianapolis, IN 46202 2859, USA
Stat Med 19:1523-30. 2000..We apply the above method to data collected in the Indianapolis-Ibadan Dementia Study to estimate the odds ratio for smoking adjusting for misclassification error...
Data management in a longitudinal cross-cultural studyR J Roberts
Department of Psychiatry, Indiana University School of Medicine, Indianapolis, USA
Stat Med 19:1645-9. 2000..Exchange visits have been needed to address data management issues and resolve unexpected problems. The data management on cross-cultural studies can be handled successfully, given careful planning...
Prevalence of cognitive impairment: data from the Indianapolis Study of Health and AgingF W Unverzagt
Department of Psychiatry, Indiana University School of Medicine, Indianapolis, IN 46202 5266, USA
Neurology 57:1655-62. 2001..The epidemiology and natural history of cognitive impairment that is not dementia is important to the understanding of normal aging and dementia...
Association of statin use with cognitive decline in elderly African AmericansS J Szwast
Department of Psychiatry, Indiana University School of Medicine, 1111 West 10th Street, PB A319, Indianapolis, IN 46202, USA
Neurology 69:1873-80. 2007..We report the results from a 3-year prospective study on the association of statin use on cognitive decline and incident dementia in elderly African Americans...
Low education and childhood rural residence: risk for Alzheimer's disease in African AmericansK S Hall
Department of Psychiatry, Indiana University School of Medicine, Indianapolis 46202 5111, USA
Neurology 54:95-9. 2000..To examine the relationship between level of education and childhood rural residence as possible risk factors for AD in African Americans in Indianapolis...
Six-item screener to identify cognitive impairment among potential subjects for clinical researchChristopher M Callahan
Indiana University Center for Aging Research, Indianapolis 46202, USA
Med Care 40:771-81. 2002..To design a brief cognitive screener with acceptable sensitivity and specificity for identifying subjects with cognitive impairment...
Informant reports of changes in personality predict dementia in a population-based study of elderly african americans and yorubaValerie Smith-Gamble
Department of Psychiatry, Indiana University School of Medicine, Indianapolis 46202, USA
Am J Geriatr Psychiatry 10:724-32. 2002....
Clinical utility of CERAD neuropsychological battery in elderly JamaicansF W Unverzagt
Department of Psychiatry, Indiana University School of Medicine, Indianapolis, USA
J Int Neuropsychol Soc 5:255-9. 1999..This study is the first to demonstrate the clinical utility of the CERAD neuropsychological battery in the differential diagnosis of memory disorders of the aged in a non-North-American sample...
Acute care utilization by dementia caregivers within urban primary care practicesCathy C Schubert
Department of Medicine, Indiana University School of Medicine, Indianapolis, IN, USA
J Gen Intern Med 23:1736-40. 2008..However, many questions remain about the characteristics of AD patients and their caregivers that contribute to this stress and how it impacts caregivers' use of healthcare resources...
Who refuses the diagnostic assessment for dementia in primary care?Malaz Boustani
Indiana University Center for Aging Research, Indianapolis, IN 46202 2872, USA
Int J Geriatr Psychiatry 21:556-63. 2006..The aim of this study was to identify the characteristics of patients who refuse a clinical diagnostic assessment for dementia after screening...
Patients' attitudes of dementia screening across the AtlanticMichael D Justiss
Indiana University Center for Aging Research, Indianapolis, IN, USA
Int J Geriatr Psychiatry 24:632-7. 2009..Implementation of these strategies will depend on the presence of a viable community or primary care based dementia screening and diagnosis program and patient acceptance of such a program...
Risk of mortality for dementia in a developing country: the Yoruba in NigeriaAnthony J Perkins
Regenstrief Institute for Health Care, 1050 Wishard Boulevard, RG6, Indianapolis, IN 46202 2872, USA
Int J Geriatr Psychiatry 17:566-73. 2002..Limited data exist on the impact of dementia in developing nations, including its association with mortality...
Association of apolipoprotein E genotype and Alzheimer disease in African AmericansJill R Murrell
Department of Pathology and Laboratory Medicine, Indiana University School of Medicine, Indianapolis, USA
Arch Neurol 63:431-4. 2006..Identification of genetic risk factors in African Americans is essential for understanding the etiology of AD...
Cognitive impairment and mortality in older primary care patientsT E Stump
Indiana University Center for Aging Research, Regenstrief Institute for Health Care, Indianapolis, Indiana 46202-2859, USA
J Am Geriatr Soc 49:934-40. 2001..Mild cognitive impairment is not associated with mortality risk, but a longer follow-up period may be necessary to identify this risk if it exists...
Mild cognitive dysfunction: an epidemiological perspective with an emphasis on African AmericansFrederick W Unverzagt
Department of Psychiatry, Indiana University School of Medicine, Indianapolis, IN 46202, USA
J Geriatr Psychiatry Neurol 20:215-26. 2007..Factors contributing to this longitudinal variability in outcomes are reviewed, including the role of medical health factors. The review closes with suggestions for next steps in the epidemiological research of mild cognitive impairment...
Selenium level is associated with apoE epsilon4 in rural elderly ChineseSujuan Gao
Department of Medicine, Indiana University School of Medicine, Indianapolis, IN 46202 2872, USA
Public Health Nutr 12:2371-6. 2009..The present paper examines the association between apoE genotype and Se levels in nail samples in a rural elderly Chinese cohort...
Apolipoprotein E and mortality in African-Americans and YorubaKathleen A Lane
Department of Medicine, Indiana University School of Medicine, Indianapolis, IN 46202, USA
J Alzheimers Dis 5:383-90. 2003..71; 95% CI: 0.45-1.10; p = 0.1238), Ibadan subjects under 75 (hazard ratio: 1.04; 95% CI: 0.78 to 1.40; p = 0.7782), or Ibadan subjects over 75 (hazard ratio: 1.21; 95% CI: 0.83 to 1.75; p = 0.3274)...
Correlates of depressive symptoms in rural elderly ChineseSujuan Gao
Department of Medicine, Indiana University School of Medicine, Indianapolis, Indiana, USA
Int J Geriatr Psychiatry 24:1358-66. 2009..Late life depression has been studied in many populations around the world. However, findings on risk factors for late life depression have remained inconsistent...
Selenium level and cognitive function in rural elderly ChineseSujuan Gao
Department of Medicine, School of Medicine, Indiana University, Indianapolis, IN, USA
Am J Epidemiol 165:955-65. 2007..Results in this geographically stable cohort support the hypothesis that a lifelong low selenium level is associated with lower cognitive function...
Implementing a screening and diagnosis program for dementia in primary careMalaz Boustani
Indiana University Center for Aging Research, Indianapolis, USA
J Gen Intern Med 20:572-7. 2005..Primary care physicians are positioned to provide early recognition and treatment of dementia. We evaluated the feasibility and utility of a comprehensive screening and diagnosis program for dementia in primary care...
Validation analysis of informant's ratings of cognitive function in African Americans and NigeriansJianzhao Shen
Department of Medicine, Indiana University School of Medicine, Indianapolis, 46202, USA
Int J Geriatr Psychiatry 21:618-25. 2006....
Prevalence rates for dementia and Alzheimer's disease in African Americans: 1992 versus 2001Kathleen S Hall
Department of Psychiatry, Indiana University School of Medicine, Indianapolis, IN, USA
Alzheimers Dement 5:227-33. 2009..This study compares age-specific and overall prevalence rates for dementia and Alzheimer's disease (AD) in two nonoverlapping, population-based cohorts of elderly African Americans in Indianapolis in 2001 and 1992...
Development and implementation of nonpharmacologic protocols for the management of patients with Alzheimer's disease and their families in a multiracial primary care settingMary Guerriero Austrom
Department of Psychiatry, Indiana University School of Medicine, 541 Clinical Dr, CL 590, Indianapolis, IN 46202, USA
Gerontologist 44:548-53. 2004....
Effectiveness of collaborative care for older adults with Alzheimer disease in primary care: a randomized controlled trialChristopher M Callahan
Indiana University Center for Aging Research, Regenstrief Institute Inc, Indiana University School of Medicine, Indianapolis 46202, USA
JAMA 295:2148-57. 2006..Most older adults with dementia will be cared for by primary care physicians, but the primary care practice environment presents important challenges to providing quality care...
Treatment of depression improves physical functioning in older adultsChristopher M Callahan
Indiana University Center for Aging Research, Indianapolis, Indiana, USA
J Am Geriatr Soc 53:367-73. 2005..To determine the effect of collaborative care management for depression on physical functioning in older adults...
Hypertension and cognitive decline in rural elderly ChineseSujuan Gao
Department of Medicine, Indiana University School of Medicine, 410 West 10th Street, Suite 3000, Indianapolis, IN 46202 2872, USA
J Am Geriatr Soc 57:1051-7. 2009..To examine the association between hypertension and cognitive decline in older adults...
Integrating care for older adults with cognitive impairmentChristopher M Callahan
Indiana University Center for Aging Research, Indiana University School of Medicine, HITS Building Suite 2000, 410 West 10th Street, Indianapolis, IN 46202 3012, USA
Curr Alzheimer Res 6:368-74. 2009..This requires investments in the design and testing of an improved infrastructure for care that matches our national investment in the search for cure...
Implementing dementia care models in primary care settings: The Aging Brain Care Medical HomeChristopher M Callahan
Indiana University Center for Aging Research, Indianapolis, USA
Aging Ment Health 15:5-12. 2011..The purpose of this article is to describe our experience in implementing a primary care-based dementia and depression care program focused on providing collaborative care for dementia and late-life depression...
Accelerated weight loss and incident dementia in an elderly African-American cohortSujuan Gao
Department of Medicine, School of Medicine, Indiana University, Indianapolis, Indiana, USA
J Am Geriatr Soc 59:18-25. 2011..To examine the association between changes in body mass index (BMI), dementia, and mild cognitive impairment (MCI)...
Trace element levels and cognitive function in rural elderly ChineseSujuan Gao
Department of Medicine, Indiana University School of Medicine, 410 West 10th Street, Suite 3000, Indianapolis, IN 46202, USA
J Gerontol A Biol Sci Med Sci 63:635-41. 2008..The relationship between trace elements measured in individual biological samples and cognitive function in an elderly population had not been investigated extensively...
Poststroke depression and treatment effects on functional outcomesA A Schmid
Roudebush VAMC, 1481 W 10th Street, 11H, Indianapolis, IN 46202 5199, USA
Neurology 76:1000-5. 2011....
Measuring primary care patients' attitudes about dementia screeningMalaz Boustani
Indiana University Center for Aging Research, Indianapolis, IN, USA
Int J Geriatr Psychiatry 23:812-20. 2008..To develop a questionnaire that will capture patients' attitudes about dementia screening in primary care...
Comorbidity profile of dementia patients in primary care: are they sicker?Cathy C Schubert
Department of Medicine, Indiana University School of Medicine, Indianapolis, Indiana, USA
J Am Geriatr Soc 54:104-9. 2006..To compare the medical comorbidity of older patients with and without dementia in primary care...
Cardiovascular risk factors and incident Alzheimer disease: a systematic review of the literatureChristianna Purnell
Regenstrief Institute Inc, Indiana University School of Medicine, Indianapolis, IN, USA
Alzheimer Dis Assoc Disord 23:1-10. 2009..The purpose of this study was to conduct a systematic review of the literature of cardiovascular factors pertaining to incident Alzheimer disease (AD)...
Predictors of life satisfaction in retired physicians and spousesMary Guerriero Austrom
Department of Psychiatry, 541 Clinical Drive, CL 590, Indiana University School of Medicine, Indianapolis, IN 46202, USA
Soc Psychiatry Psychiatr Epidemiol 38:134-41. 2003..The factors predicting life satisfaction and change in life satisfaction following retirement differed for physicians and spouses. For physicians, life satisfaction and change in life satisfaction were affected by time since retirement...
Screening for cognitive impairment and depression in ethnically diverse older populationsMary Ganguli
University of Pittsburgh, Pittsburgh, PA, USA
Alzheimer Dis Assoc Disord 19:275-8. 2005..The context, costs, and objectives of screening a given population should be considered when selecting a screening instrument and a threshold on the scale, whether for clinical or research purposes...
Perspectives on depression, mild cognitive impairment, and cognitive declineDavid C Steffens
Department of Psychiatry and Behavioral Sciences, Duke University School of Medicine, Durham, NC 27710, USA
Arch Gen Psychiatry 63:130-8. 2006....
The Stick Design test: a new measure of visuoconstructional abilityOlusegun Baiyewu
Department of Psychiatry, College of Medicine, University of Ibadan, Ibadan, Nigeria
J Int Neuropsychol Soc 11:598-605. 2005..We conclude that Stick Design is a reasonable test of visuoconstructional ability in older cohorts with very limited educational exposure and literacy...
Behavioral and caregiver reaction of dementia as measured by the neuropsychiatric inventory in Nigerian community residentsOlusegun Baiyewu
Department of Psychiatry, University of Ibadan, Ibadan, Nigeria
Int Psychogeriatr 15:399-409. 2003..The Neuropsychiatric Inventory (NPI) has been used to assess behavioral symptoms of dementia in the United States, Taiwan, Japan, and Italy...
Prevalence estimates of depression in elderly community-dwelling African Americans in Indianapolis and Yoruba in Ibadan, NigeriaOlusegun Baiyewu
Department of Psychiatry, College of Medicine, University of Ibadan, Nigeria
Int Psychogeriatr 19:679-89. 2007..This is a community-based longitudinal epidemiological comparative study of elderly African Americans in Indianapolis and elderly Yoruba in Ibadan, Nigeria...
Genetic variation in apolipoprotein D affects the risk of Alzheimer disease in African-AmericansPurnima P Desai
Department of Human Genetics, University of Pittsburgh, Pittsburgh, Pennsylvania 15261, USA
Am J Med Genet B Neuropsychiatr Genet 116:98-101. 2003..14; P = 0.13). Our data suggest that the risk of AD among African-Americans may be modified by genetic variation in APOD. Larger population-based or case-control studies are needed to confirm the role of APOD genetic variation in AD...
APOE epsilon4 is not associated with Alzheimer's disease in elderly NigeriansOye Gureje
Department of Psychiatry, University of Ibadan, College of Medicine, Ibadan, Nigeria
Ann Neurol 59:182-5. 2006..This lack of association in the Yoruba might reflect genetic variation, environmental factors, as well as genetic/environmental interactions...
Diagnosis and assessment of Alzheimer's disease in diverse populationsPeggye Dilworth-Anderson
Department of Health Policy and Administration, School of Public Health and Institute on Aging, University of North Carolina, Chapel Hill, NC, USA
Alzheimers Dement 4:305-9. 2008
