Alon Harris

Summary

Affiliation: Indiana University
Country: USA

Publications

  1. ncbi request reprint An update on retinal circulation assessment technologies
    Ehud Rechtman
    Department of Ophthalmology, Indiana University School of Medicine, Indianapolis, Indiana 46202, USA
    Curr Eye Res 27:329-43. 2003
  2. pmc Age-related macular degeneration and the aging eye
    Rita Ehrlich
    Indiana University School of Medicine, Department of Ophthalmology, Indianapolis, IN 46202, USA
    Clin Interv Aging 3:473-82. 2008
  3. pmc Update and critical appraisal of combined timolol and carbonic anhydrase inhibitors and the effect on ocular blood flow in glaucoma patients
    Adam M Moss
    Department of Ophthalmology, Indiana University School of Medicine, Indianapolis, Indiana, USA
    Clin Ophthalmol 4:233-41. 2010
  4. pmc Ocular hemodynamics and glaucoma: the role of mathematical modeling
    Alon Harris
    Department of Ophthalmology, Indiana University School of Medicine, Indianapolis, USA
    Eur J Ophthalmol 23:139-46. 2013
  5. ncbi request reprint Nocturnal blood pressure reduction: effect on retrobulbar hemodynamics in glaucoma
    Alon Harris
    Department of Ophthalmology, Indiana University School of Medicine, 702 Rotary Circle, Rm 137, Indianapolis 46202 5175, USA
    Graefes Arch Clin Exp Ophthalmol 240:372-8. 2002
  6. ncbi request reprint Effect of intravenous droperidol on intraocular pressure and retrobulbar hemodynamics
    A Harris
    Department of Ophthalmology, Indiana University School of Medicine, Indianapolis 46202, USA
    Eur J Ophthalmol 12:193-9. 2002
  7. ncbi request reprint Reduced cerebrovascular blood flow velocities and vasoreactivity in open-angle glaucoma
    Alon Harris
    Department of Ophthalmology, Indiana University School of Medicine, Indianapolis, Indiana, USA
    Am J Ophthalmol 135:144-7. 2003
  8. ncbi request reprint The role of optic nerve blood flow in the pathogenesis of glaucoma
    Alon Harris
    Department of Ophthalmology, Room 137, Indiana University School of Medicine, 702 Rotary Circle, Indianapolis, IN 46202, USA
    Ophthalmol Clin North Am 18:345-53, v. 2005
  9. pmc Blood flow per unit retinal nerve fibre tissue volume is lower in the human inferior retina
    A Harris
    Department of Ophthalmology, Indiana University School of Medicine, Indianapolis, USA
    Br J Ophthalmol 87:184-8. 2003
  10. ncbi request reprint Relationship of cerebral blood flow and central visual function in primary open-angle glaucoma
    Alon Harris
    Department of Ophthalmology, Indiana University School of Medicine, Indianapolis, IN 46202, USA
    J Glaucoma 16:159-63. 2007

Collaborators

Detail Information

Publications97

  1. ncbi request reprint An update on retinal circulation assessment technologies
    Ehud Rechtman
    Department of Ophthalmology, Indiana University School of Medicine, Indianapolis, Indiana 46202, USA
    Curr Eye Res 27:329-43. 2003
  2. pmc Age-related macular degeneration and the aging eye
    Rita Ehrlich
    Indiana University School of Medicine, Department of Ophthalmology, Indianapolis, IN 46202, USA
    Clin Interv Aging 3:473-82. 2008
    ..Understanding the pathophysiology of AMD development can help guide future research to further comprehend this disease and to develop better treatments to prevent its irreversible central vision loss in the elderly...
  3. pmc Update and critical appraisal of combined timolol and carbonic anhydrase inhibitors and the effect on ocular blood flow in glaucoma patients
    Adam M Moss
    Department of Ophthalmology, Indiana University School of Medicine, Indianapolis, Indiana, USA
    Clin Ophthalmol 4:233-41. 2010
    ....
  4. pmc Ocular hemodynamics and glaucoma: the role of mathematical modeling
    Alon Harris
    Department of Ophthalmology, Indiana University School of Medicine, Indianapolis, USA
    Eur J Ophthalmol 23:139-46. 2013
    ..To discuss the role of mathematical modeling in studying ocular hemodynamics, with a focus on glaucoma...
  5. ncbi request reprint Nocturnal blood pressure reduction: effect on retrobulbar hemodynamics in glaucoma
    Alon Harris
    Department of Ophthalmology, Indiana University School of Medicine, 702 Rotary Circle, Rm 137, Indianapolis 46202 5175, USA
    Graefes Arch Clin Exp Ophthalmol 240:372-8. 2002
    ..The present study aimed to find out whether reductions in nocturnal BP are linked to retrobulbar blood flow perturbations in glaucoma patients...
  6. ncbi request reprint Effect of intravenous droperidol on intraocular pressure and retrobulbar hemodynamics
    A Harris
    Department of Ophthalmology, Indiana University School of Medicine, Indianapolis 46202, USA
    Eur J Ophthalmol 12:193-9. 2002
    ..We examined the acute effects of intravenous infusion of a dopamine blocker (droperidol) on these parameters in healthy humans...
  7. ncbi request reprint Reduced cerebrovascular blood flow velocities and vasoreactivity in open-angle glaucoma
    Alon Harris
    Department of Ophthalmology, Indiana University School of Medicine, Indianapolis, Indiana, USA
    Am J Ophthalmol 135:144-7. 2003
    ..To compare cerebral blood flow velocities between open-angle glaucoma (OAG) patients and controls, at baseline and during hyperoxia...
  8. ncbi request reprint The role of optic nerve blood flow in the pathogenesis of glaucoma
    Alon Harris
    Department of Ophthalmology, Room 137, Indiana University School of Medicine, 702 Rotary Circle, Indianapolis, IN 46202, USA
    Ophthalmol Clin North Am 18:345-53, v. 2005
    ..The aim of this review is to cover the possible role of optic nerve head hemodynamics in the pathogenesis of glaucoma...
  9. pmc Blood flow per unit retinal nerve fibre tissue volume is lower in the human inferior retina
    A Harris
    Department of Ophthalmology, Indiana University School of Medicine, Indianapolis, USA
    Br J Ophthalmol 87:184-8. 2003
    ..To determine if perfusion per unit tissue volume of retinal nerve fibre layer and optic nerve head in the inferior sector is lower than in the superior sector...
  10. ncbi request reprint Relationship of cerebral blood flow and central visual function in primary open-angle glaucoma
    Alon Harris
    Department of Ophthalmology, Indiana University School of Medicine, Indianapolis, IN 46202, USA
    J Glaucoma 16:159-63. 2007
    ..To investigate the relations between middle cerebral artery (MCA) blood flow velocities and central visual function measured by foveal cone electroretinograms (ERG) and visual field...
  11. ncbi request reprint Comparative analysis of the effects of dorzolamide and latanoprost on ocular hemodynamics in normal tension glaucoma patients
    A Harris
    Department of Ophthalmology, Indiana University School of Medicine, Indianapolis 46202, USA
    Eur J Ophthalmol 13:24-31. 2003
    ..To compare the effects of latanoprost (Xalatan) and dorzolamide (Trusopt) on ocular hemodynamics in normal-tension glaucoma patients...
  12. pmc The effects of dorzolamide on choroidal and retinal perfusion in non-exudative age related macular degeneration
    A Harris
    Department of Ophthalmology, Indiana University School of Medicine, IN 46260, USA
    Br J Ophthalmol 87:753-7. 2003
    ..To comprehensively evaluate the effects of dorzolamide on the choroidal and retinal circulation in patients with age related macular degeneration (AMD)...
  13. doi request reprint Measuring and interpreting ocular blood flow and metabolism in glaucoma
    Alon Harris
    Department of Ophthalmology, Indiana University School of Medicine, 702 Rotary Circle, Indianapolis, IN 46202, USA
    Can J Ophthalmol 43:328-36. 2008
    ....
  14. ncbi request reprint Progress in measurement of ocular blood flow and relevance to our understanding of glaucoma and age-related macular degeneration
    A Harris
    Department of Ophthalmology, Indiana University, Indianapolis 46202, USA
    Prog Retin Eye Res 18:669-87. 1999
    ..This paper is a comprehensive update describing modalities available for the measurement of all new ocular blood flow in human and the clinical use...
  15. ncbi request reprint Assessment of human ocular hemodynamics
    A Harris
    Department of Ophthalmology, Indiana University School of Medicine, Indianapolis 46202, USA
    Surv Ophthalmol 42:509-33. 1998
    ....
  16. ncbi request reprint Aging affects the retrobulbar circulation differently in women and men
    A Harris
    Department of Ophthalmology, Indiana University, School of Medicine, Indianapolis, IN 46202 USA
    Arch Ophthalmol 118:1076-80. 2000
    ..Because glaucoma and age-related macular degeneration are closely linked to advanced age, we performed a cross-sectional study using color Doppler imaging of 4 retrobulbar vessels in both healthy women and men...
  17. ncbi request reprint Effect of dorzolamide timolol combination versus timolol 0.5% on ocular bloodflow in patients with primary open-angle glaucoma
    A Harris
    Department of Ophthalmology, Indiana University School of Medicine, 702 Rotary Circle, Indianapolis, IN 46202, USA
    Am J Ophthalmol 132:490-5. 2001
    ..Addition of dorzolamide to timolol in primary open-angle glaucoma shows augmented reduction of intraocular pressure. It is unknown as yet if addition of dorzolamide will alter hemodynamics...
  18. doi request reprint The effect of sildenafil on ocular blood flow
    A Harris
    Department of Ophthalmology, Indiana University School of Medicine, 702 Rotary Circle, Indianapolis, IN 46202, USA
    Br J Ophthalmol 92:469-73. 2008
    ..Sildenafil appears to increase blood flow velocity significantly in the retrobulbar and choroidal circulation. Most studies suggest an increase in choroidal blood flow, with a lesser effect on the retinal vasculature...
  19. ncbi request reprint Simultaneous management of blood flow and IOP in glaucoma
    A Harris
    Department of Ophthalmology, Indiana University School of Medicine, Indianapolis, IN 46202 5175, USA
    Acta Ophthalmol Scand 79:336-41. 2001
    ..Consequently, neuroprotective treatments for glaucoma should be designed to both reduce IOP and improve ocular nutrient delivery...
  20. doi request reprint The effect of latanoprost on ocular blood flow
    Alon Harris
    Department of Ophthalmology, Indiana University School of Medicine, Indianapolis, IN 46202, USA
    Int Ophthalmol 29:19-26. 2009
    ..To investigate the effect of latanoprost on ocular hemodynamics in healthy subjects...
  21. doi request reprint Ocular blood flow and oxygen delivery to the retina in primary open-angle glaucoma patients: the addition of dorzolamide to timolol monotherapy
    Brent Siesky
    Department of Ophthalmology, Indiana University School of Medicine, Indianapolis, Indiana, USA
    Acta Ophthalmol 88:142-9. 2010
    ..The combination of increased retinal blood flow with consistent oxygen saturation may potentially increase oxygen delivery to the retina...
  22. doi request reprint Impaired ocular blood flow regulation in patients with open-angle glaucoma and diabetes
    Yochai Shoshani
    Department of Ophthalmology, Indiana School of Medicine Midwest Eye Institute, 702 Rotary Circle, Indianapolis, IN 46202, USA
    Clin Experiment Ophthalmol 40:697-705. 2012
    ..To elucidate the potential impact of diabetes mellitus on primary open-angle glaucoma pathology through vascular deficiency...
  23. ncbi request reprint A comparative analysis of the effects of the fixed combination of timolol and dorzolamide versus latanoprost plus timolol on ocular hemodynamics and visual function in patients with primary open-angle glaucoma
    Brent Siesky
    Department of Ophthalmology, Indiana University School of Medicine, Indianapolis, IN 46202, USA
    J Ocul Pharmacol Ther 22:353-61. 2006
    ....
  24. doi request reprint Intravitreal bevacizumab for choroidal neovascularization secondary to presumed ocular histoplasmosis syndrome
    Rita Ehrlich
    Department of Ophthalmology, Indiana University School of Medicine, Indianapolis, IN 46202, USA
    Retina 29:1418-23. 2009
    ..The purpose of this study was to assess the efficacy of intravitreal bevacizumab for choroidal neovascularization resulting from presumed ocular histoplasmosis syndrome...
  25. doi request reprint Repeatability of retrobulbar blood flow velocity measured using color Doppler imaging in the Indianapolis Glaucoma Progression Study
    Rita Ehrlich
    Department of Ophthalmology, Indiana School of Medicine, Indianapolis, IN, USA
    J Glaucoma 20:540-7. 2011
    ..Determine the repeatability of color Doppler imaging (CDI) measurements in patients with open-angle glaucoma (OAG)...
  26. ncbi request reprint The effects of raloxifene hydrochloride on ocular hemodynamics and visual function
    Brent Siesky
    Department of Ophthalmology, Indiana University School of Medicine, 702 Rotary Circle, Indianapolis, IN 46202, USA
    Int Ophthalmol 29:225-30. 2009
    ..To assess the comprehensive effects of raloxifene hydrochloride on retinal, choroidal and retrobulbar hemodynamics and on visual function in post-menopausal women...
  27. doi request reprint Age-related ocular vascular changes
    Rita Ehrlich
    Department of Ophthalmology, Indiana University School of Medicine, Indianapolis, IN, USA
    Graefes Arch Clin Exp Ophthalmol 247:583-91. 2009
    ..Age-related vascular changes have been demonstrated in ocular tissue, and the incidence and prevalence of diseases such as macular degeneration, glaucoma and vascular occlusive diseases increase significantly with age...
  28. doi request reprint Association of open-angle glaucoma with perfusion pressure status in the Thessaloniki Eye Study
    Fotis Topouzis
    Department of Ophthalmology, School of Medicine, Aristotle University of Thessaloniki, American Hellenic Educational Progressive Association AHEPA Hospital, Thessaloniki, Greece
    Am J Ophthalmol 155:843-51. 2013
    ....
  29. doi request reprint Short-term effects of brimonidine/timolol and dorzolamide/timolol on ocular perfusion pressure and blood flow in glaucoma
    Brent Siesky
    Department of Ophthalmology, Indiana University School of Medicine, Indianapolis, 46202, USA
    Adv Ther 29:53-63. 2012
    ..To examine the comparative short-term effects of brimonidine/timolol and dorzolamide/timolol on ocular perfusion pressure and retrobulbar blood flow in patients with primary open angle glaucoma (OAG)...
  30. doi request reprint Agreement among three examiners of colour Doppler imaging retrobulbar blood flow velocity measurements
    Panayiota Founti
    Department of Ophthalmology, School of Medicine, Aristotle University of Thessaloniki, AHEPA Hospital, Thessaloniki, Greece
    Acta Ophthalmol 89:e631-4. 2011
    ..To assess the agreement among three masked examiners on central retinal artery (CRA) and ophthalmic artery (OA) blood flow velocity measurements performed with colour Doppler imaging (CDI) in healthy volunteers...
  31. doi request reprint Interobserver repeatability of heidelberg retinal flowmetry using pixel-by-pixel analysis
    Itay Ben Zion
    Department of Ophthalmology, Indiana University School of Medicine, Indianapolis, IN, USA
    J Glaucoma 18:280-3. 2009
    ..To determine the interobserver reproducibility of Heidelberg retinal flowmeter (HRF) blood flow measurements using independently selected study areas for pixel-by-pixel analysis...
  32. doi request reprint A comparative study of the effects of brinzolamide and dorzolamide on retinal oxygen saturation and ocular microcirculation in patients with primary open-angle glaucoma
    B Siesky
    Department of Ophthalmology, Indiana University School of Medicine, 702 Rotary Circle, Rm 137, Indianapolis, IN 46202, USA
    Br J Ophthalmol 92:500-4. 2008
    ..To assess the effects of brinzolamide and dorzolamide on ocular haemodynamics and retinal oxygen saturation in patients with primary open-angle glaucoma (OAG)...
  33. doi request reprint Effects of exercise on intraocular pressure and ocular blood flow: a review
    David Risner
    Department of Ophthalmology, Indiana University School of Medicine, Indianapolis, IN, USA
    J Glaucoma 18:429-36. 2009
    ..The effects of exercise on the prevention of glaucoma and glaucomatous progression remain unknown. The role of exercise in glaucoma management should be investigated...
  34. ncbi request reprint Comparison of ocular hemodynamics measured by a new retinal blood flowmeter and color Doppler imaging
    Larry Kagemann
    Department of Ophthalmology, Indiana University School of Medicine, Indianapolis, Indiana 46202, USA
    Ophthalmic Surg Lasers Imaging 34:342-7. 2003
    ..To compare measurements of a new retinal blood flow device with central retinal artery blood velocity...
  35. ncbi request reprint Dye dependent differences in arteriovenous passage times: a comparison of indocyanine green and fluorescein sodium dye analysis
    Daniel T Sines
    Department of Ophthalmology, Indiana University School of Medicine, Indianapolis, IN 46202, USA
    Ophthalmic Surg Lasers Imaging 39:203-8. 2008
    ..To evaluate the difference in arteriovenous passage time calculated from retinal angiograms using indocyanine green and fluorescein sodium dye in healthy individuals...
  36. pmc Pulsatile ocular blood flow: relationship with flow velocities in vessels supplying the retina and choroid
    Itay Ben Zion
    Department of Ophthalmology, Indiana University School of Medicine, Indianapolis, IN 46202, USA
    Br J Ophthalmol 91:882-4. 2007
    ..Although ocular tonography measures a pulsatile component of the ocular perfusion, the retinal and/or choroidal components of this pulsatile flow remain undefined...
  37. ncbi request reprint Effect of brimonidine tartrate on ocular hemodynamics in healthy volunteers
    C P Jonescu-Cuypers
    Glaucoma Research and Diagnostic Center, Department of Ophthalmology, Indiana University Medical Center, Indianapolis 46202, USA
    J Ocul Pharmacol Ther 17:199-205. 2001
    ..In conclusion, two-week treatment with brimonidine reduces IOP and does not reduce the bulk retinal or retrobulbar arterial perfusion in young healthy volunteers...
  38. doi request reprint Retinal oxygen saturation and metabolism: how does it pertain to glaucoma? An update on the application of retinal oximetry in glaucoma
    Leslie A Tobe
    Department of Ophthalmology, Indiana University School of Medicine, Indianapolis, USA
    Eur J Ophthalmol 23:465-72. 2013
    ..To discuss the techniques and mechanisms of retinal oximetry with a focus on utilization of retinal oximetry in the assessment of retinal oxygen saturation in glaucoma...
  39. doi request reprint Association of the optic disc structure with the use of antihypertensive medications: the thessaloniki eye study
    Alon Harris
    Department of Ophthalmology, Indiana University, School of Medicine, Indianapolis, IN, USA
    J Glaucoma 22:526-31. 2013
    ..To investigate the association of antihypertensive medications with optic disc structure by blood pressure (BP) level, in nonglaucoma subjects...
  40. doi request reprint Endothelin and its suspected role in the pathogenesis and possible treatment of glaucoma
    Yochai Z Shoshani
    Department of Ophthalmology, Indiana School of Medicine, Indianapolis, Indiana 46202, USA
    Curr Eye Res 37:1-11. 2012
    ....
  41. doi request reprint Risk factors for primary open-angle glaucoma and pseudoexfoliative glaucoma in the Thessaloniki eye study
    Fotis Topouzis
    Department of Ophthalmology, School of Medicine, Aristotle University of Thessaloniki, American Hellenic Educational Progressive Association AHEPA Hospital, Thessaloniki, Greece
    Am J Ophthalmol 152:219-228.e1. 2011
    ..To investigate risk factors for primary open-angle glaucoma (POAG) and pseudoexfoliative glaucoma (PEXG) in the Thessaloniki Eye Study...
  42. ncbi request reprint Diabetic macular oedema: physical, physiological and molecular factors contribute to this pathological process
    Rita Ehrlich
    Department of Ophthalmology, Indiana University School of Medicine, Indianapolis, USA
    Acta Ophthalmol 88:279-91. 2010
    ..However, by attempting to understand the pathways involved in DMO, we can help guide new treatment options targeted towards specific factors or mediators...
  43. doi request reprint Feasibility of creating a normative database of colour Doppler imaging parameters in glaucomatous eyes and controls
    Deepam Rusia
    Letzter Professor of Ophthalmology, Professor of Physiology and Biophysics, Indiana University School of Medicine, Indianapolis, Indiana 46202, USA
    Br J Ophthalmol 95:1193-8. 2011
    ..Because the mean values for glaucomatous and normal eyes have overlapping ranges, caution should be used when classifying glaucoma status based on a single CDI measurement...
  44. ncbi request reprint Comparison of visual function and ocular hemodynamics between pre- and post-menopausal women
    B A Siesky
    Department of Ophthalmology, Indiana University School of Medicine, Indianapolis, IN 46202 USA
    Eur J Ophthalmol 18:320-3. 2008
    ..The purpose of this investigation was to determine the effects of menopause on visual function and cardiovascular and ocular hemodynamics...
  45. doi request reprint Combined treatment of intravitreal bevacizumab and intravitreal triamcinolone in patients with retinal vein occlusion: 6 months of follow-up
    Rita Ehrlich
    Department of Ophthalmology, Indiana University School of Medicine, 702 Rotary Circle, Indianapolis, IN 46202, USA
    Graefes Arch Clin Exp Ophthalmol 248:375-80. 2010
    ..To report 6 months of results of combined treatment of intravitreal bevacizumab and triamcinolone in patients with retinal vein occlusion (RVO)...
  46. pmc Theoretical analysis of vascular regulatory mechanisms contributing to retinal blood flow autoregulation
    Julia Arciero
    Department of Mathematical Sciences, Indiana University Purdue University Indianapolis, Indianapolis, Indiana 46202, USA
    Invest Ophthalmol Vis Sci 54:5584-93. 2013
    ..In this study, a vascular wall mechanics model is used to predict the relative importance of regulatory mechanisms in achieving retinal autoregulation...
  47. doi request reprint Literature review and meta-analysis of topical carbonic anhydrase inhibitors and ocular blood flow
    Brent Siesky
    Department of Ophthalmology, Indiana University School of Medicine, Indianapolis, Indiana, USA
    Surv Ophthalmol 54:33-46. 2009
    ..Based on this meta-analysis, we conclude that topical carbonic anhydrase inhibitors increase ocular blood flow velocities in the retinal circulation, central retinal and short posterior ciliary arteries, but not in the ophthalmic artery...
  48. doi request reprint Contrast sensitivity, ocular blood flow and their potential role in assessing ischaemic retinal disease
    Yochai Z Shoshani
    Department of Ophthalmology, Indiana School of Medicine, Indianapolis, Indiana 46202, USA
    Acta Ophthalmol 89:e382-95. 2011
    ..To examine the definition, evaluation methodology, association to ocular blood flow and potential clinical value of contrast sensitivity (CS) testing in clinical and research settings, focusing in patients with ischemic retinal disease...
  49. ncbi request reprint In vitro simulation of the first technique for non-invasive measurement of volumetric ophthalmic artery blood flow in humans
    Brent Siesky
    Department of Ophthalmology, Indiana University School of Medicine, Indianapolis, Indiana, USA
    Ophthalmic Surg Lasers Imaging 41:375-82. 2010
    ..To evaluate the accuracy, reproducibility, and variability of volumetric flow measurements taken by color Doppler imaging ultrasound, using an in vitro "phantom" model to simulate the ophthalmic artery...
  50. doi request reprint The circadian variations in systemic blood pressure, ocular perfusion pressure, and ocular blood flow: risk factors for glaucoma?
    Adam Werne
    Department of Ophthalmology, Indiana University School of Medicine, Indianapolis, Indiana, USA
    Surv Ophthalmol 53:559-67. 2008
    ..No consensus concerning circadian variations in ocular blood flow exists in the current literature, and future investigations of nocturnal changes in blood flow and glaucoma progression are required...
  51. doi request reprint Increased likelihood of glaucoma at the same screening intraocular pressure in subjects with pseudoexfoliation: the Thessaloniki Eye Study
    Fotis Topouzis
    Department of Ophthalmology, School of Medicine, Aristotle University of Thessaloniki, AHEPA Hospital, Thessaloniki, Greece
    Am J Ophthalmol 148:606-613.e1. 2009
    ....
  52. ncbi request reprint [An updated review of methods for human retinal oximetry measurements and current applications]
    Itay Ben-Zion
    Department of Ophthalmology, Indiana University School of Medicine, Indianapolis, Indiana, USA
    Harefuah 147:812-7, 836. 2008
    ..It is clear that a thorough understanding of retinal oxygen tension is vital to our understanding of normal retinal physiology and the pathophysiology of degenerative eye diseases...
  53. ncbi request reprint Nanotechnology and glaucoma: a review of the potential implications of glaucoma nanomedicine
    Nathaniel J Kim
    Department of Ophthalmology, Indiana University School of Medicine, Indianapolis, Indiana, USA
    Br J Ophthalmol 98:427-31. 2014
    ..However, more research is needed to better elucidate the mechanism of cellular entry, the potential for nanoparticle cytotoxicity and the assurance of clinical efficacy. ..
  54. pmc Choroidal perfusion perturbations in non-neovascular age related macular degeneration
    Thomas A Ciulla
    Department of Ophthalmology, Indiana University School of Medicine, Indianapolis, USA
    Br J Ophthalmol 86:209-13. 2002
    ..This study more objectively compared choroidal perfusion parameters in a group with non-neovascular AMD to an unaffected age matched control group...
  55. doi request reprint Goldmann applanation tonometry and dynamic contour tonometry are not correlated with central corneal thickness in primary open angle glaucoma
    Guy Regev
    Department of Ophthalmology, Indiana University School of Medicine, Indianapolis, IN, USA
    J Glaucoma 20:282-6. 2011
    ..To compare intraocular pressure (IOP) measured by Goldmann applanation tonometry (GAT) and dynamic contour tonometry (DCT) and assess their relationship to central corneal thickness (CCT) in patients with primary open angle glaucoma (OAG)...
  56. ncbi request reprint Ocular perfusion abnormalities in diabetes
    Thomas A Ciulla
    Midwest Eye Institute, Indianapolis, Indiana, USA
    Acta Ophthalmol Scand 80:468-77. 2002
    ..To review the role of ocular perfusion in the pathophysiology of diabetic retinopathy, one of the leading causes of irreversible blindness in the industrialized world...
  57. ncbi request reprint The response of retrobulbar vasculature to hypercapnia in primary open-angle glaucoma and ocular hypertension
    D Sines
    Department of Ophthalmology, Indiana University School of Medicine, Indianapolis, IN 46202, USA
    Ophthalmic Res 39:76-80. 2007
    ..To evaluate the physiological effects of hypercapnia on the retrobulbar vasculature in ocular hypertension (OH) and open-angle glaucoma (OAG)...
  58. ncbi request reprint Intraocular pressure, blood pressure, and retinal blood flow autoregulation: a mathematical model to clarify their relationship and clinical relevance
    Giovanna Guidoboni
    Department of Mathematical Sciences, Indiana University Purdue University Indianapolis, Indianapolis, Indiana, United States Eugene and Marilyn Glick Eye Institute and Department of Ophthalmology, Indiana University School of Medicine, Indianapolis, Indiana, United States
    Invest Ophthalmol Vis Sci 55:4105-18. 2014
    ..This study investigates the relationship between intraocular pressure (IOP) and retinal hemodynamics and predicts how arterial blood pressure (BP) and blood flow autoregulation (AR) influence this relationship...
  59. ncbi request reprint Generic medications in ophthalmology
    Matt Zore
    Department of Ophthalmology, Indiana University School of Medicine, Indianapolis, Indiana 46202, USA
    Br J Ophthalmol 97:253-7. 2013
    ..In particular, the challenges of assuring bioequivalence and therapeutic equivalence in topical ophthalmic drugs will be examined...
  60. ncbi request reprint Improving the analysis of arteriovenous passage times
    Christopher Pesavento
    Department of Ophthalmology, Indiana University School of Medicine, 702 Rotary Circle, Indianapolis, IN 46202, USA
    Graefes Arch Clin Exp Ophthalmol 240:955-9. 2002
    ....
  61. doi request reprint Central retinal artery originating from the temporal short posterior ciliary artery associated with intraorbital external-to-internal carotid arterial anastomoses
    Mohammadali M Shoja
    Department of Ophthalmology, Ocular Vascular Research Center, Glaucoma Research and Diagnostic Center, Eugene and Marilyn Glick Eye Institute, Indiana University School of Medicine, Indianapolis, IN 46202, USA
    Surg Radiol Anat 34:187-9. 2012
    ..A brief review of CRA variations and potential clinical significances of the observed variant are discussed...
  62. ncbi request reprint The impact of glaucoma medication on parameters of ocular perfusion
    A Harris
    Glaucoma Research and Diagnostic Center, Department of Ophthalmology, Indiana University School of Medicine, Indianapolis, Indiana 46202, USA
    Curr Opin Ophthalmol 12:131-7. 2001
    ..The various claims for enhancements or reduction of ocular circulation within each class of medication are reviewed and evaluated...
  63. ncbi request reprint Dorzolamide hydrochloride and visual function in normal eyes
    W E Sponsel
    Department of Ophthalmology, University of Texas Health Science Center, San Antonio, USA
    Am J Ophthalmol 123:759-66. 1997
    ....
  64. pmc Cerebral blood flow in glaucoma patients
    Alon Harris
    Department of Ophthalmology, Glick Eye Institute, Indiana University Medical Center, Indianapolis, IN, USA
    J Glaucoma 22:S46-8. 2013
    ....
  65. ncbi request reprint Intravitreal triamcinolone for choroidal neovascularization in ocular histoplasmosis syndrome
    Ehud Rechtman
    Department of Ophthalmology, Indiana University School of Medicine, Indianapolis, Indiana 46202, USA
    Am J Ophthalmol 136:739-41. 2003
    ..To report the effects of intravitreal triamcinolone acetonide injections for subfoveal and juxtafoveal choroidal neovascularization (CNV) in ocular histoplasmosis syndrome...
  66. ncbi request reprint Color Doppler imaging of retrobulbar hemodynamics in Sturge-Weber syndrome-associated glaucoma
    D Neely
    Department of Ophthalmology, Indiana University School of Medicine, Indianapolis, USA
    Eur J Ophthalmol 18:172-6. 2008
    ..The exact cause of glaucoma in SWS is poorly understood and difficult to treat. The purpose of this study is to investigate the ocular hemodynamics of children with SWS-associated glaucoma using color Doppler imaging techniques...
  67. ncbi request reprint Ocular perfusion and age-related macular degeneration
    T A Ciulla
    Indiana University School of Medicine, Indianapolis, Indiana, USA
    Acta Ophthalmol Scand 79:108-15. 2001
    ..Further study is warranted...
  68. ncbi request reprint Cerebrospinal fluid pressure and glaucoma: regulation of trans-lamina cribrosa pressure
    Brian Marek
    Department of Ophthalmology, Eugene and Marilyn Glick Eye Institute, Indianapolis, Indiana, USA
    Br J Ophthalmol 98:721-5. 2014
    ..Given the interaction of various pressures, their role in glaucoma pathophysiology has come under investigation and warrants further study in order to better understand the aetiology and progression of glaucoma. ..
  69. ncbi request reprint Longitudinal assessment of plus disease in retinopathy of prematurity using color Doppler imaging
    Daniel Neely
    Indiana University School of Medicine, Department of Ophthalmology, Indianapolis, 46202, USA
    J AAPOS 13:509-11. 2009
    ..Color Doppler imaging did not appear to be a clinically useful tool in the longitudinal management of ROP, nor did it appear to be useful as an objective determinant of plus disease in these premature infants...
  70. ncbi request reprint A review of methods for human retinal oximetry
    Alon Harris
    Department of Ophthalmology, Glaucoma Research and Diagnostic Center, Indianapolis, Indiana 46202, USA
    Ophthalmic Surg Lasers Imaging 34:152-64. 2003
    ..This article discusses the various approaches that have been taken to estimate the oxygen saturation in the retinal vasculature. Advantages and limitations of each are discussed. Data from human and animal subjects are also presented...
  71. ncbi request reprint The influence of retinal blood flow on open-angle glaucoma in patients with and without diabetes
    Eric Lee
    Department of Ophthalmology, Indiana University School of Medicine, Indianapolis USA
    Eur J Ophthalmol 24:542-9. 2014
    ..These data suggest that changes in retinal blood flow may play a larger role in glaucomatous ONH progression in patients with OAG with DM. ..
  72. pmc Blood pressure, ocular perfusion pressure, and body mass index in glaucoma patients
    Sandra Ngo
    Department of Ophthalmology, Indiana University School of Medicine, Indianapolis, IN 46202, USA
    Eur J Ophthalmol 23:664-9. 2013
    ..To investigate relationships between blood pressure (BP), ocular perfusion pressure (OPP), and intraocular pressure (IOP) in patients with open-angle glaucoma (OAG) of different body mass index (BMI) classes. 
..
  73. ncbi request reprint An update on photodynamic therapy in age-related macular degeneration
    Ehud Rechtman
    Department of Ophthalmology, Indiana University School of Medicine, Indianapolis, 46202, USA
    Expert Opin Pharmacother 3:931-8. 2002
    ..This review covers AMD epidemiology, the mechanism of PDT, the 2-year results of the two major clinical studies of PDT with verteporfin, the cost-effectiveness of PDT and the current research status of other drugs for PDT in AMD...
  74. ncbi request reprint Transpupillary thermotherapy for subfoveal occult choroidal neovascularization: effect on ocular perfusion
    T A Ciulla
    Department of Ophthalmology, Indiana University School of Medicine, 702 Rotary Circle, Indianapolis, IN 46260, USA
    Invest Ophthalmol Vis Sci 42:3337-40. 2001
    ..To perform a descriptive analysis of the effects on ocular blood flow of transpupillary thermotherapy (TTT) for occult subfoveal choroidal neovascular membranes (CNVMs) in age-related macular degeneration (AMD)...
  75. ncbi request reprint Correlates of acute exercise-induced ocular hypotension
    A Harris
    Department of Ophthalmology, Indiana University School of Medicine, Indianapolis 46202 5175
    Invest Ophthalmol Vis Sci 35:3852-7. 1994
    ..To understand those factors that determine the decrease in intraocular pressure (IOP) that occurs during acute dynamic exercise...
  76. doi request reprint The role of transforming growth factor β in glaucoma and the therapeutic implications
    Mark A Prendes
    Department of Ophthalmology, Indiana University School of Medicine, Indianapolis, IN 46202, USA
    Br J Ophthalmol 97:680-6. 2013
    ..This review will cover previous investigative studies and discuss the current understanding of TGF-β's role in glaucoma and how it may serve as a potential therapeutic target...
  77. pmc Dysfunctional regulation of ocular blood flow: A risk factor for glaucoma?
    Danny Moore
    Department of Ophthalmology, Indiana University School of Medicine, Indianapolis, IN, USA
    Clin Ophthalmol 2:849-61. 2008
    ..Included in this review are discussions of conditions thought to contribute to vascular regulatory dysfunction in OAG, including atherosclerosis, vasospasm, and endothelial dysfunction...
  78. pmc The first technique for non-invasive measurements of volumetric ophthalmic artery blood flow in humans
    F Orge
    Departments of Ophthalmology and Physiology, Indiana University School of Medicine, Indianapolis IN, USA
    Br J Ophthalmol 86:1216-9. 2002
    ..To validate the first non-invasive measurements of volumetric ophthalmic artery blood flow in humans...
  79. pmc Acute IOP elevation with scleral suction: effects on retrobulbar haemodynamics
    A Harris
    Department of Ophthalmology, Indiana University, School of Medicine, Indianapolis, USA
    Br J Ophthalmol 80:1055-9. 1996
    ..This study investigated the relation of mechanical to vascular factors by examining how acute IOP elevation altered flow velocities in the central retinal and ophthalmic arteries...
  80. ncbi request reprint Ocular changes in pregnancy
    Robert B Dinn
    Indiana University School of Medicine, Indianapolis 46202, USA
    Obstet Gynecol Surv 58:137-44. 2003
    ..Furthermore, pregnancy is associated with a decreased intraocular pressure in healthy eyes, and the effects of glaucoma medications on the fetus and breast-fed infant are largely unknown...
  81. pmc Intravitreal triamcinolone with photodynamic therapy for subfoveal choroidal neovascularisation in age related macular degeneration
    E Rechtman
    Department of Ophthalmology, Indiana University School of Medicine, Indianapolis, IN, USA
    Br J Ophthalmol 88:344-7. 2004
    ....
  82. ncbi request reprint Effects of timolol and dorzolamide on retrobulbar hemodynamics in patients with newly diagnosed primary open-angle glaucoma
    Fernando Galassi
    Department of Oto Neuro Ophthalmological Surgery, Section of Ophthalmology, University of Florence, Italy
    Ophthalmologica 216:123-8. 2002
    ..The resistance decrease observed after dorzolamide treatment in the ciliary circulation may be due to the decrease in intraocular pressure or a possible direct vasodilating effect of the drug...
  83. ncbi request reprint The effects of antiglaucoma and systemic medications on ocular blood flow
    Vital P Costa
    Glaucoma Service, University of Campinas, Rua Bauru, 40, São Paulo 01248 010, Brazil
    Prog Retin Eye Res 22:769-805. 2003
    ..Longitudinal, prospective, randomized trials are needed to investigate the effects of vasoactive substances with no hypotensive effect on the progression of glaucoma...
  84. ncbi request reprint Association of blood pressure status with the optic disk structure in non-glaucoma subjects: the Thessaloniki eye study
    Fotis Topouzis
    II Department of Ophthalmology, Aristotle University of Thessaloniki, Thessaloniki, Greece
    Am J Ophthalmol 142:60-67. 2006
    ..To study the association of blood pressure (BP) status on the optic disk structure as measured with the Heidelberg Retina Tomograph (HRT) in people without glaucoma...
  85. doi request reprint Choroidal blood flow regulation and possible implications to glaucoma
    Ehud Rechtman
    Clin Experiment Ophthalmol 36:111-2. 2008
  86. ncbi request reprint Vascular abnormalities in glaucoma: from population-based studies to the clinic?
    Alon Harris
    Am J Ophthalmol 145:595-7. 2008
  87. ncbi request reprint Prevalence of open-angle glaucoma in Greece: the Thessaloniki Eye Study
    Fotis Topouzis
    II Department of Ophthalmology, Aristotle University of Thessaloniki, Thessaloniki, Greece
    Am J Ophthalmol 144:511-9. 2007
    ..To estimate the prevalence of open-angle glaucoma (OAG) in a population-based sample of subjects 60 years of age or older in Thessaloniki, Greece...
  88. ncbi request reprint Effect of acetazolamide on ocular hemodynamics in pseudotumor cerebri associated with inflammatory bowel disease
    Max A Villain
    Service d Ophtalmologie, Hopital Gui de Chauliac, Centre Hospitalo Universitaire de Montpellier, Montpellier, France
    Am J Ophthalmol 134:778-80. 2002
    ..To describe the hemodynamic effect of oral acetazolamide administration on ocular perfusion in a patient with pseudotumor cerebri associated with Crohn disease...
  89. ncbi request reprint Factors associated with undiagnosed open-angle glaucoma: the Thessaloniki Eye Study
    Fotis Topouzis
    II Department of Ophthalmology, Aristotle University of Thessaloniki, General Hospital Papageorgiou, Periferiaki Odos Thessalonikis N Efkarpia 56403, Thessaloniki, Greece
    Am J Ophthalmol 145:327-335. 2008
    ..To identify factors associated with undiagnosed open-angle glaucoma (OAG), primary open-angle glaucoma (POAG), and pseudoexfoliative glaucoma (PEXG) in an elderly population in Thessaloniki, Greece...
  90. ncbi request reprint Reproducibility of pixel-by-pixel analysis of Heidelberg retinal flowmetry images: the Thessaloniki Eye Study
    Leonidas Mavroudis
    II Department of Ophthalmology, Aristotle University of Thessaloniki, Thessaloniki, Greece
    Acta Ophthalmol 86:81-6. 2008
    ..To identify the investigator effect in the analysis results of Heidelberg retinal flowmetry (HRF) images when pixel-by-pixel analysis is performed...
  91. ncbi request reprint The relationship between retrobulbar and choroidal hemodynamics in non-neovascular age-related macular degeneration
    Ehud Rechtman
    Goldschleger Eye Institute, Tel Hashomer, Israel
    Ophthalmic Surg Lasers Imaging 38:219-25. 2007
    ..To evaluate the relationship between retrobulbar and choroidal hemodynamics in non-neovascular age-related macular degeneration...
  92. ncbi request reprint The effects of droperidol in perforating keratoplasty
    Hanna J Garzozi
    Departments of Ophthalmology and Anesthesiology, Bnai Zion Medical Center, Rappaport Faculty of Medicine Technion, Haifa, Israel
    Ophthalmologica 220:242-5. 2006
    ..To evaluate the intraoperative and postoperative effects of droperidol administered with general anesthesia during perforating keratoplasty...
  93. ncbi request reprint Dorzolamide and ocular blood flow in previously untreated glaucoma patients: a controlled double-masked study
    Ingar C Bergstrand
    Department of Ophthalmology, Malmo University Hospital, Malmo, Sweden
    Acta Ophthalmol Scand 80:176-82. 2002
    ..The aim of this study was to investigate the haemodynamic effects of topical dorzolamide treatment in eyes with newly detected and previously untreated glaucoma...
  94. ncbi request reprint Evaluation of retinal haemodynamics and retinal function after application of dorzolamide, timolol and latanoprost in newly diagnosed open-angle glaucoma patients
    Oliver Arend
    Department of Ophthalmology, Medical School, Technical University Aachen, Pauwelsstrasse 30, Aachen 52057, Germany
    Acta Ophthalmol Scand 81:474-9. 2003
    ..Haemodynamics were assessed using fluorescein angiography by means of a scanning laser ophthalmoscope (SLO). Visual function and visual field indices were evaluated during all drug treatment phases...
  95. ncbi request reprint Prevalence of age-related macular degeneration in Greece: the Thessaloniki Eye Study
    Fotis Topouzis
    II Department of Ophthalmology, Aristotle University of Thessaloniki, Thessaloniki, Greece
    Am J Ophthalmol 142:1076-9. 2006
    ..To estimate the age- and gender-specific prevalence of age-related macular degeneration (AMD) in a population-based sample of subjects 60 years of age or older in Thessaloniki, Greece...
  96. ncbi request reprint Automatic retinal oximetry
    Sveinn Hakon Hardarson
    Department of Ophthalmology, University of Iceland, National Univbersity Hospital, Reykjavik, Iceland
    Invest Ophthalmol Vis Sci 47:5011-6. 2006
    ..To measure hemoglobin oxygen saturation (SO(2)) in retinal vessels and to test the reproducibility and sensitivity of an automatic spectrophotometric oximeter...
  97. ncbi request reprint Change in IOP in myopic eyes after excimer laser refractive surgery
    H J Garzozi
    J Refract Surg 18:89-90. 2002