Mark Goebl

Summary

Affiliation: Indiana University
Country: USA

Publications

  1. pmc Nutrient sensing kinases PKA and Sch9 phosphorylate the catalytic domain of the ubiquitin-conjugating enzyme Cdc34
    Ross Cocklin
    Department of Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis, Indiana, United States of America
    PLoS ONE 6:e27099. 2011
  2. pmc The loop-less tmCdc34 E2 mutant defective in polyubiquitination in vitro and in vivo supports yeast growth in a manner dependent on Ubp14 and Cka2
    Agnieszka Lass
    Edward A, Doisy Department of Biochemistry and Molecular Biology, Saint Louis University School of Medicine, St, Louis, MO 63104, USA
    Cell Div 6:7. 2011
  3. pmc SCF E3-mediated autoubiquitination negatively regulates activity of Cdc34 E2 but plays a nonessential role in the catalytic cycle in vitro and in vivo
    K Matthew Scaglione
    Edward A Doisy Department of Biochemistry and Molecular Biology, Saint Louis University School of Medicine, St Louis, MO 63104, USA
    Mol Cell Biol 27:5860-70. 2007
  4. pmc New insight into the role of the Cdc34 ubiquitin-conjugating enzyme in cell cycle regulation via Ace2 and Sic1
    Ross Cocklin
    Department of Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis, Indiana 46202 2111, USA
    Genetics 187:701-15. 2011
  5. ncbi request reprint Alpha-lipoic acid modulates ovarian surface epithelial cell growth
    E Vig-Varga
    Department of Biochemistry and Molecular Biology, Indiana University School of Medicine and Walther Oncology Institute, Indianapolis, IN 46220, USA
    Gynecol Oncol 103:45-52. 2006
  6. ncbi request reprint The ubiquitin ligase SCFGrr1 is necessary for pheromone sensitivity in Saccharomyces cerevisiae
    Kelly Schweitzer
    Department of Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis, IN 46202, USA
    Yeast 22:553-64. 2005
  7. ncbi request reprint The expression level of luciferase within tumour cells can alter tumour growth upon in vivo bioluminescence imaging
    Susan Brutkiewicz
    Department of Obstetrics and Gynecology, Indiana University School of Medicine, Indianapolis, IN 46202, USA
    Luminescence 22:221-8. 2007
  8. pmc The antibiotic gentamicin inhibits specific protein trafficking functions of the Arf1/2 family of GTPases
    Lin Lin
    Department of Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis, IN 46202, USA
    Antimicrob Agents Chemother 55:246-54. 2011

Collaborators

Detail Information

Publications8

  1. pmc Nutrient sensing kinases PKA and Sch9 phosphorylate the catalytic domain of the ubiquitin-conjugating enzyme Cdc34
    Ross Cocklin
    Department of Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis, Indiana, United States of America
    PLoS ONE 6:e27099. 2011
    ..Cells monitor changes in their environment through nutrient sensing protein kinases. Thus Cdc34 phosphorylation by PKA and Sch9 provides a direct tether between G1 cell division events and cell growth...
  2. pmc The loop-less tmCdc34 E2 mutant defective in polyubiquitination in vitro and in vivo supports yeast growth in a manner dependent on Ubp14 and Cka2
    Agnieszka Lass
    Edward A, Doisy Department of Biochemistry and Molecular Biology, Saint Louis University School of Medicine, St, Louis, MO 63104, USA
    Cell Div 6:7. 2011
    ..abstract:..
  3. pmc SCF E3-mediated autoubiquitination negatively regulates activity of Cdc34 E2 but plays a nonessential role in the catalytic cycle in vitro and in vivo
    K Matthew Scaglione
    Edward A Doisy Department of Biochemistry and Molecular Biology, Saint Louis University School of Medicine, St Louis, MO 63104, USA
    Mol Cell Biol 27:5860-70. 2007
    ..We discuss the implications of these findings for the mechanism of Cdc34 function with SCF...
  4. pmc New insight into the role of the Cdc34 ubiquitin-conjugating enzyme in cell cycle regulation via Ace2 and Sic1
    Ross Cocklin
    Department of Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis, Indiana 46202 2111, USA
    Genetics 187:701-15. 2011
    ..A screen for mutations that interact with CDC34(tm) uncovered novel regulators of Sic1, including genes encoding the polyubiquitin chain receptors Rad23 and Rpn10...
  5. ncbi request reprint Alpha-lipoic acid modulates ovarian surface epithelial cell growth
    E Vig-Varga
    Department of Biochemistry and Molecular Biology, Indiana University School of Medicine and Walther Oncology Institute, Indianapolis, IN 46220, USA
    Gynecol Oncol 103:45-52. 2006
    ..Our studies were designed to investigate the effect of alpha-lipoic acid (ALA), a naturally occurring antioxidant, on a key inflammatory signaling pathway and cell proliferation in normal and tumorigenic ovarian surface epithelial cells...
  6. ncbi request reprint The ubiquitin ligase SCFGrr1 is necessary for pheromone sensitivity in Saccharomyces cerevisiae
    Kelly Schweitzer
    Department of Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis, IN 46202, USA
    Yeast 22:553-64. 2005
    ..Thus, rapid loss of Cln-kinase activity during mating may require coordinated inactivation of the Cln-kinase complexes, inactivation of CLN transcription and SCF(Grr1)-dependent Cln degradation...
  7. ncbi request reprint The expression level of luciferase within tumour cells can alter tumour growth upon in vivo bioluminescence imaging
    Susan Brutkiewicz
    Department of Obstetrics and Gynecology, Indiana University School of Medicine, Indianapolis, IN 46202, USA
    Luminescence 22:221-8. 2007
    ..The observation that a high level of luciferase expression will inhibit tumour cell growth when an animal is subjected to serial in vivo bioluminescence imaging is potentially an important factor in designing these types of studies...
  8. pmc The antibiotic gentamicin inhibits specific protein trafficking functions of the Arf1/2 family of GTPases
    Lin Lin
    Department of Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis, IN 46202, USA
    Antimicrob Agents Chemother 55:246-54. 2011
    ..These results suggest that one consequence of gentamicin exposure is disruption of Arf-dependent protein trafficking...