Affiliation: Indiana University
- The loop-less tmCdc34 E2 mutant defective in polyubiquitination in vitro and in vivo supports yeast growth in a manner dependent on Ubp14 and Cka2Agnieszka Lass
Edward A, Doisy Department of Biochemistry and Molecular Biology, Saint Louis University School of Medicine, St, Louis, MO 63104, USA
Cell Div 6:7. 2011..abstract:..
- SCF E3-mediated autoubiquitination negatively regulates activity of Cdc34 E2 but plays a nonessential role in the catalytic cycle in vitro and in vivoK Matthew Scaglione
Edward A Doisy Department of Biochemistry and Molecular Biology, Saint Louis University School of Medicine, St Louis, MO 63104, USA
Mol Cell Biol 27:5860-70. 2007..We discuss the implications of these findings for the mechanism of Cdc34 function with SCF...
- Alpha-lipoic acid modulates ovarian surface epithelial cell growthE Vig-Varga
Department of Biochemistry and Molecular Biology, Indiana University School of Medicine and Walther Oncology Institute, Indianapolis, IN 46220, USA
Gynecol Oncol 103:45-52. 2006..Our studies were designed to investigate the effect of alpha-lipoic acid (ALA), a naturally occurring antioxidant, on a key inflammatory signaling pathway and cell proliferation in normal and tumorigenic ovarian surface epithelial cells...
- The antibiotic gentamicin inhibits specific protein trafficking functions of the Arf1/2 family of GTPasesLin Lin
Department of Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis, IN 46202, USA
Antimicrob Agents Chemother 55:246-54. 2011..These results suggest that one consequence of gentamicin exposure is disruption of Arf-dependent protein trafficking...