Swapan K Ghosh

Summary

Affiliation: Indiana State University
Country: USA

Publications

  1. doi request reprint Synthetic adjuvants for vaccine formulations: phytol derivatives
    Swapan K Ghosh
    Indiana State University, Department of Biology, Terre Haute, IN 47809, USA
    Expert Opin Drug Deliv 10:437-50. 2013
  2. doi request reprint Efficacy of phytol-derived diterpenoid immunoadjuvants over alum in shaping the murine host's immune response to Staphylococcus aureus
    Roshni Roy Chowdhury
    Department of Biology, Indiana State University, Terre Haute, IN 47809, USA
    Vaccine 31:1178-86. 2013
  3. doi request reprint Synthetic adjuvants for vaccine formulations: evaluation of new phytol derivatives in induction and persistence of specific immune response
    Youssef Aachoui
    Department of Biology, Indiana State University, Terre Haute, IN 47809, United States
    Cell Immunol 271:308-18. 2011
  4. pmc Immune enhancement by novel vaccine adjuvants in autoimmune-prone NZB/W F1 mice: relative efficacy and safety
    Youssef Aachoui
    Department of Biology, Indiana State University, Terre Haute, IN 47809, USA
    BMC Immunol 12:61. 2011
  5. pmc Extracellular matrix from porcine small intestinal submucosa (SIS) as immune adjuvants
    Youssef Aachoui
    Department of Biology, Indiana State University, Terre Haute, Indiana, United States of America
    PLoS ONE 6:e27083. 2011
  6. pmc Effects of small intestinal submucosa (SIS) on the murine innate immune microenvironment induced by heat-killed Staphylococcus aureus
    Roshni Roy Chowdhury
    Department of Biology, Indiana State University, Terre Haute, Indiana, United States of America
    PLoS ONE 7:e48724. 2012
  7. doi request reprint Molecular signatures of phytol-derived immunostimulants in the context of chemokine-cytokine microenvironment and enhanced immune response
    Youssef Aachoui
    Department of Biology, Indiana State University, Terre Haute, IN 47809, USA
    Cell Immunol 271:227-38. 2011
  8. pmc Phytol-derived novel isoprenoid immunostimulants
    Roshni Roy Chowdhury
    Department of Biology, Indiana State University Terre Haute, IN, USA
    Front Immunol 3:49. 2012

Collaborators

Detail Information

Publications8

  1. doi request reprint Synthetic adjuvants for vaccine formulations: phytol derivatives
    Swapan K Ghosh
    Indiana State University, Department of Biology, Terre Haute, IN 47809, USA
    Expert Opin Drug Deliv 10:437-50. 2013
    ..Currently, adjuvant selection is largely empirical, but the mechanism underlying adjuvanticity is beginning to unravel. This should help develop more defined or targeted adjuvants...
  2. doi request reprint Efficacy of phytol-derived diterpenoid immunoadjuvants over alum in shaping the murine host's immune response to Staphylococcus aureus
    Roshni Roy Chowdhury
    Department of Biology, Indiana State University, Terre Haute, IN 47809, USA
    Vaccine 31:1178-86. 2013
    ..aureus immune microenvironment. In summary, our study provides evidence for the better effectiveness of phytol-derived immunoadjuvants over alum in enhancing anti-S. aureus immunity...
  3. doi request reprint Synthetic adjuvants for vaccine formulations: evaluation of new phytol derivatives in induction and persistence of specific immune response
    Youssef Aachoui
    Department of Biology, Indiana State University, Terre Haute, IN 47809, United States
    Cell Immunol 271:308-18. 2011
    ..Finally, unlike squalene and several other terpenoids reported to date, these phytol derivatives did not appear arthritogenic in murine models...
  4. pmc Immune enhancement by novel vaccine adjuvants in autoimmune-prone NZB/W F1 mice: relative efficacy and safety
    Youssef Aachoui
    Department of Biology, Indiana State University, Terre Haute, IN 47809, USA
    BMC Immunol 12:61. 2011
    ..Phytol derivatives are hydrophobic, oil-in water diterpenoids, while alum is hydrophilic, and SIS is essentially a biodegradable and collagenous protein cocktail derived from extracellular matrices...
  5. pmc Extracellular matrix from porcine small intestinal submucosa (SIS) as immune adjuvants
    Youssef Aachoui
    Department of Biology, Indiana State University, Terre Haute, Indiana, United States of America
    PLoS ONE 6:e27083. 2011
    ..Lastly, it was as effective as alum in engendering a lasting and specific antibody response, primarily of IgG1 type...
  6. pmc Effects of small intestinal submucosa (SIS) on the murine innate immune microenvironment induced by heat-killed Staphylococcus aureus
    Roshni Roy Chowdhury
    Department of Biology, Indiana State University, Terre Haute, Indiana, United States of America
    PLoS ONE 7:e48724. 2012
    ..aureus. These results have practical implications in developing strategies to contain infection and promote successful tissue repair...
  7. doi request reprint Molecular signatures of phytol-derived immunostimulants in the context of chemokine-cytokine microenvironment and enhanced immune response
    Youssef Aachoui
    Department of Biology, Indiana State University, Terre Haute, IN 47809, USA
    Cell Immunol 271:227-38. 2011
    ..We also noted enhanced expression of NLRP genes including NLRP3 with both alum and phytol derivatives (particularly PHIS-01)...
  8. pmc Phytol-derived novel isoprenoid immunostimulants
    Roshni Roy Chowdhury
    Department of Biology, Indiana State University Terre Haute, IN, USA
    Front Immunol 3:49. 2012
    ..Additionally, the phytol-derived compounds have no cumulative inflammatory or toxic effects even in immuno-compromised mice...