Holly J Garringer

Summary

Affiliation: Indiana University
Country: USA

Publications

  1. pmc Increased tau phosphorylation and tau truncation, and decreased synaptophysin levels in mutant BRI2/tau transgenic mice
    Holly J Garringer
    Department of Pathology and Laboratory Medicine and Indiana Alzheimer Disease Center, Indiana University School of Medicine, Indianapolis, Indiana, United States of America
    PLoS ONE 8:e56426. 2013
  2. doi request reprint Modeling familial British and Danish dementia
    Holly J Garringer
    Department of Pathology and Laboratory Medicine, Indiana Alzheimer Disease Center, Indiana University School of Medicine, 635 Barnhill Drive MSB A136, Indianapolis, IN, 46202, USA
    Brain Struct Funct 214:235-44. 2010
  3. pmc Unraveling of the E-helices and disruption of 4-fold pores are associated with iron mishandling in a mutant ferritin causing neurodegeneration
    Martin A Baraibar
    Department of Pathology and Laboratory Medicine, Indiana University School of Medicine, Indianapolis, Indiana 46202, USA
    J Biol Chem 285:1950-6. 2010
  4. pmc The Psen1-L166P-knock-in mutation leads to amyloid deposition in human wild-type amyloid precursor protein YAC transgenic mice
    Ruben Vidal
    Department of Pathology and Laboratory Medicine, Indiana University School of Medicine, Indianapolis, Indiana 46202, USA
    FASEB J 26:2899-910. 2012
  5. pmc Abnormal iron metabolism and oxidative stress in mice expressing a mutant form of the ferritin light polypeptide gene
    Ana G Barbeito
    Department of Pathology and Laboratory Medicine, Indiana Alzheimer Disease Center, Indiana University School of Medicine, Indianapolis, Indiana 46202, USA
    J Neurochem 109:1067-78. 2009

Collaborators

Detail Information

Publications5

  1. pmc Increased tau phosphorylation and tau truncation, and decreased synaptophysin levels in mutant BRI2/tau transgenic mice
    Holly J Garringer
    Department of Pathology and Laboratory Medicine and Indiana Alzheimer Disease Center, Indiana University School of Medicine, Indianapolis, Indiana, United States of America
    PLoS ONE 8:e56426. 2013
    ..Our data provide new in vivo insights into the pathogenesis of FDD and the pathogenic pathway(s) by which amyloidogenic peptides, regardless of their primary amino acid sequence, can cause neurodegeneration...
  2. doi request reprint Modeling familial British and Danish dementia
    Holly J Garringer
    Department of Pathology and Laboratory Medicine, Indiana Alzheimer Disease Center, Indiana University School of Medicine, 635 Barnhill Drive MSB A136, Indianapolis, IN, 46202, USA
    Brain Struct Funct 214:235-44. 2010
    ..In this review, a comprehensive account of the advances in the development of animal models for FBD and FDD and of their relevance to the study of Alzheimer disease is presented...
  3. pmc Unraveling of the E-helices and disruption of 4-fold pores are associated with iron mishandling in a mutant ferritin causing neurodegeneration
    Martin A Baraibar
    Department of Pathology and Laboratory Medicine, Indiana University School of Medicine, Indianapolis, Indiana 46202, USA
    J Biol Chem 285:1950-6. 2010
    ....
  4. pmc The Psen1-L166P-knock-in mutation leads to amyloid deposition in human wild-type amyloid precursor protein YAC transgenic mice
    Ruben Vidal
    Department of Pathology and Laboratory Medicine, Indiana University School of Medicine, Indianapolis, Indiana 46202, USA
    FASEB J 26:2899-910. 2012
    ..This model will allow the study of AD pathogenesis and testing of therapeutic strategies in a more relevant environment without experimental artifacts due to the overexpression of a single-mutant AβPP isoform using exogenous promoters...
  5. pmc Abnormal iron metabolism and oxidative stress in mice expressing a mutant form of the ferritin light polypeptide gene
    Ana G Barbeito
    Department of Pathology and Laboratory Medicine, Indiana Alzheimer Disease Center, Indiana University School of Medicine, Indianapolis, Indiana 46202, USA
    J Neurochem 109:1067-78. 2009
    ....