Research Topics
| K H FifeSummaryAffiliation: Indiana University Country: USA Publications
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Publications
A comparison of one year of episodic or suppressive treatment of recurrent genital herpes with valacyclovirKenneth H Fife
Department of Medicine, Indiana University School of Medicine, Indianapolis, Indiana, USA
Sex Transm Dis 34:297-301. 2007..We conducted this study to compare episodic and suppressive therapy for genital herpes about disease characteristics, disease burden, and psychologic impact...
Prevalence and persistence of cervical human papillomavirus infection in HIV-positive women initiating highly active antiretroviral therapyKenneth H Fife
Department of Medicine, Indiana University School of Medicine, Indianapolis, IN 46202 5124, USA
J Acquir Immune Defic Syndr 51:274-82. 2009....- Predictors of herpes simplex virus type 2 antibody positivity among persons with no history of genital herpesKenneth H Fife
Department of Medicine, Indiana University School of Medicine, Indianapolis 46202, USA
Sex Transm Dis 31:676-81. 2004..The demographic, historical, and behavioral factors that predict a positive herpes simplex virus type 2 (HSV-2) antibody test in persons without a history of genital herpes have not been well-defined... - Incidence and prevalence of herpes simplex virus infections in adolescent womenKenneth H Fife
Department of Medicine, Indiana University School of Medicine, Indianapolis, Indiana 46202, USA
Sex Transm Dis 33:441-4. 2006..We conducted this study to examine the incidence, prevalence, and risk factors for herpes simplex virus (HSV) 1 and HSV 2 infection in a cohort of young women who were closely followed for acquisition of sexually transmitted infections... - Effect of resiquimod 0.01% gel on lesion healing and viral shedding when applied to genital herpes lesionsKenneth H Fife
Division of Infectious Diseases, Departmernt of Medicine, Indiana University School of Medicine, Emerson Hall 435, 545 Barnhill Drive, Indianapolis, IN 46202, USA
Antimicrob Agents Chemother 52:477-82. 2008..471; 95% confidence interval, 0.786 to 2.754; P = 0.227). Application of resiquimod 0.01% two times per week for 3 weeks did not delay the healing of genital herpes lesions or reduce acute viral shedding... - Effect of valacyclovir on viral shedding in immunocompetent patients with recurrent herpes simplex virus 2 genital herpes: a US-based randomized, double-blind, placebo-controlled clinical trialKenneth H Fife
Indiana University School of Medicine, Room 435 Emerson Hall, 545 Barnhill Dr, Indianapolis, IN 46202, USA
Mayo Clin Proc 81:1321-7. 2006.... - Poor sensitivity of polymerase chain reaction assays of genital skin swabs and urine to detect HPV 6 and 11 DNA in menKenneth H Fife
Department of Medicine, Indiana University School of Medicine, Indianapolis, Indiana, USA
Sex Transm Dis 30:246-8. 2003..A possible reason for the failure to detect human papillomavirus (HPV) DNA in asymptomatic men who are likely to be infected is the sensitivity of the detection methods... - Treatment of external genital warts in men using 5% imiquimod cream applied three times a week, once daily, twice daily, or three times a dayK H Fife
Department of Medicine, Indiana University School of Medicine, Indianapolis, USA
Sex Transm Dis 28:226-31. 2001..When 5% imiquimod cream is applied three times a week up to 16 weeks, approximately two thirds of women treated with imiquimod achieve complete clearance of genital warts, whereas only about one third of men clear completely... 
Implementation of routine access to herpes simplex virus type 2 antibody testing in a public health sexually transmitted disease clinicKenneth H Fife
Department of Medicine, Indiana University School of Medicine, Indianapolis, IN, USA
Sex Transm Dis 36:724-8. 2009..Client characteristics associated with HSV-2 rapid antibody test uptake and test positivity were analyzed in clients attending an urban sexually transmitted disease clinic...- An international, randomized, double-blind, placebo-controlled, study of valacyclovir for the suppression of herpes simplex virus type 2 genital herpes in newly diagnosed patientsKenneth H Fife
Department of Medicine, Division of Infectious Diseases, Indiana University School of Medicine, Emerson Hall, Room 435, 545 Barnhill Drive, Indianapolis, IN 46202, USA
Sex Transm Dis 35:668-73. 2008.... - Neutralization of human papillomavirus type 11 (HPV-11) by serum from women vaccinated with yeast-derived HPV-11 L1 virus-like particles: correlation with competitive radioimmunoassay titerD R Brown
Indiana University School of Medicine and Roudebush Veterans Administration Hospital, 545 Barnhill Dr, Indianapolis, IN 46202, USA
J Infect Dis 184:1183-6. 2001..Immunization with HPV VLPs elicits a vigorous serum immune response in a high percentage of women. The HPV-11 cRIA titer appears to be a surrogate marker for neutralization... - Detection of multiple human papillomavirus types in Condylomata acuminata lesions from otherwise healthy and immunosuppressed patientsD R Brown
Department of Medicine, Indiana University School of Medicine, Indianapolis, Indiana 46202 5124, USA
J Clin Microbiol 37:3316-22. 1999..Further studies are needed to determine the influence these additional HPV types have on the epidemiology of genital tract HPV infections and the natural history of condylomata acuminata, especially in immunosuppressed patients... - Detection of multiple human papillomavirus types in the lower genital tract correlates with cervical dysplasiaK H Fife
Department of Medicine, Indiana University School of Medicine, Indianapolis, Indiana, USA
J Med Virol 64:550-9. 2001..04 (range 0-7) HPV types among those with normal cytology (P < 0.0001). These data support a possible role for multiple HPV types in the development or progression of cervical dysplasia... - Dose-ranging studies of the safety and immunogenicity of human papillomavirus Type 11 and Type 16 virus-like particle candidate vaccines in young healthy womenKenneth H Fife
Department of Medicine, Indiana University School of Medicine, Indianapolis, USA
Vaccine 22:2943-52. 2004..Antibody to HPV11 and 16 was still present at Month 36 in 96.8 and 93.5% of vaccinees, respectively. Both vaccines were well tolerated and were associated with only mild to moderate injection-site reactions... - Factors predicting the acceptance of herpes simplex virus type 2 antibody testing among adolescents and young adultsGregory D Zimet
Department of Pediatrics, Indiana University School of Medicine, Indianapolis, USA
Sex Transm Dis 31:665-9. 2004..The rates and determinants of acceptance of herpes simplex virus type 2 (HSV-2) testing have not been adequately studied... - Return for results after herpes simplex virus type 2 screeningJ Dennis Fortenberry
Indiana University School of Medicine, Indianapolis, USA
Sex Transm Dis 31:655-8. 2004..The objective of this study was to evaluate factors associated with return for results of type-specific herpes simplex virus (HSV) screening... - Early assessment of the efficacy of a human papillomavirus type 16 L1 virus-like particle vaccineDarron R Brown
Department of Medicine, Indiana University School of Medicine, Emerson Hall Room 435, 545 Barnhill Drive, Indianapolis 46022, USA
Vaccine 22:2936-42. 2004..These results support the institution of larger efficacy trials for HPV L1 VLP vaccines... - Viability and effectiveness of large-scale HIV treatment initiatives in sub-Saharan Africa: experience from western KenyaKara Wools-Kaloustian
Division of Infectious Diseases, Indiana University School of Medicine, Indianapolis, IN 46202, USA
AIDS 20:41-8. 2006..To determine the clinical and immunological outcomes of a cohort of HIV-infected patients receiving antiretroviral therapy... - Growth of molluscum contagiosum virus in a human foreskin xenograft modelK H Fife
Department of Medicine, Indiana University School of Medicine, Indianapolis, USA
Virology 226:95-101. 1996..A limited number of attempts to pass virus from one infected implant to another were not successful. This system is the most rapid and reproducible for growing MCV that has been reported to date... - Functional characterization of the C---C chemokine-like molecules encoded by molluscum contagiosum virus types 1 and 2M D Krathwohl
Department of Medicine, Indiana University School of Medicine, Indianapolis, IN 46202, USA
Proc Natl Acad Sci U S A 94:9875-80. 1997..The significance of hematopoietic progenitor cell inhibition in viral pathogenesis is uncertain... - Bariatric surgery outcomes in HIV-infected subjects: a case seriesHenry Selke
Department of Medicine, Division of Infectious Diseases, Indiana University School of Medicine, Indianapolis, Indiana, USA
AIDS Patient Care STDS 24:545-50. 2010..Larger studies are needed to verify these results, especially in regards to surgical complications... - Are the antiherpes nucleosides really all the same?Kenneth H Fife
Sex Transm Dis 33:534-5. 2006 - Herpes virus type 2 infection and genital symptoms in primary care patientsDouglas T Fleming
Mathematica Policy Research, Inc, Princeton, New Jersey, USA
Sex Transm Dis 33:416-21. 2006..50; 95% CI, 1.06-2.11). HSV-2 was not significantly associated with other types of genital symptoms. CONCLUSIONS: Primary-care physicians should consider unrecognized HSV-2 infection as a potential cause of some common genital symptoms... - The effect of daily valacyclovir suppression on herpes simplex virus type 2 viral shedding in HSV-2 seropositive subjects without a history of genital herpesRhoda S Sperling
Mount Sinai Medical Center, New York City, New York, USA
Sex Transm Dis 35:286-90. 2008..These individuals can transmit disease during periods of asymptomatic viral shedding. The frequency of asymptomatic shedding and the efficacy of antiviral therapy in reducing shedding has not been assessed in this population... - A randomized controlled trial of a replication defective (gH deletion) herpes simplex virus vaccine for the treatment of recurrent genital herpes among immunocompetent subjectsGuy de Bruyn
Program in Infectious Diseases, Fred Hutchinson Cancer Research Center, Seattle, WA, USA
Vaccine 24:914-20. 2006..4%, respectively). CONCLUSION: This replication incompetent HSV-2 vaccine lacking the glycoprotein H gene was safe but had no clinical or virologic benefit in the amelioration of genital HSV-2 disease among immunocompetent men and women... - The Centers for Disease Control and Prevention revised recommendations for HIV testing: reactions of women attending community health clinicsJoe W Burrage
Indiana University School of Nursing, USA
J Assoc Nurses AIDS Care 19:66-74. 2008..In general, respondents believed that verbal informed consent for testing as well as provision of HIV-related information before and after testing were crucial...