Michael J Ferkowicz

Summary

Affiliation: Indiana University
Country: USA

Publications

  1. ncbi Blood island formation: longstanding observations and modern interpretations
    Michael J Ferkowicz
    Herman B Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, Ind 46202, USA
    Exp Hematol 33:1041-7. 2005
  2. ncbi Endothelial cells in the early murine yolk sac give rise to CD41-expressing hematopoietic cells
    Weiming Li
    Department of Pediatrics, Herman B Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, IN 46202, USA
    Stem Cells Dev 14:44-54. 2005
  3. ncbi Whole embryo imaging of hematopoietic cell emergence and migration
    Michael J Ferkowicz
    Department of Pediatrics, Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, IN, USA
    Methods Mol Biol 750:143-55. 2011
  4. ncbi Embryonic day 9 yolk sac and intra-embryonic hemogenic endothelium independently generate a B-1 and marginal zone progenitor lacking B-2 potential
    Momoko Yoshimoto
    Department of Pediatrics, Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, IN 46202, USA
    Proc Natl Acad Sci U S A 108:1468-73. 2011
  5. ncbi Identification of a novel hierarchy of endothelial progenitor cells using human peripheral and umbilical cord blood
    David A Ingram
    Department of Pediatrics, Herman B Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis 46202, USA
    Blood 104:2752-60. 2004
  6. ncbi Mitochondrial targeting of human O6-methylguanine DNA methyltransferase protects against cell killing by chemotherapeutic alkylating agents
    Shanbao Cai
    Section of Hematology/Oncology, Department of Pediatrics, Herman B Wells Center for Pediatric Research, Indiana University School of Medicine, 1044 West Walnut, R4-302C, Indianapolis, IN 46202, USA
    Cancer Res 65:3319-27. 2005
  7. ncbi CD41 expression defines the onset of primitive and definitive hematopoiesis in the murine embryo
    Michael J Ferkowicz
    Department of Pediatrics, Indiana University School of Medicine, Indianapolis, IN 46202, USA
    Development 130:4393-403. 2003
  8. ncbi Rac1 is essential for intraembryonic hematopoiesis and for the initial seeding of fetal liver with definitive hematopoietic progenitor cells
    Gabriel Ghiaur
    Department of Pediatrics, Cincinnati Children s Research Foundation and Cincinnati Children s Hospital Medical Center, and Hoxworth Blood Center, University of Cincinnati College of Medicine, OH, USA
    Blood 111:3313-21. 2008
  9. ncbi PECAM-1 is expressed on hematopoietic stem cells throughout ontogeny and identifies a population of erythroid progenitors
    Christina I Baumann
    Center for Hematologic Malignancies, Division of Hematology and Medical Oncology, Department of Medicine, Oregon Health and Sciences University UHN73C 3181 SW Sam Jackson Park Rd, 97239, USA
    Blood 104:1010-6. 2004
  10. ncbi Tumor necrosis factor-alpha and endothelial cells modulate Notch signaling in the bone marrow microenvironment during inflammation
    Luis Fernandez
    Center of Regenerative Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, Mass, USA
    Exp Hematol 36:545-558. 2008

Collaborators

Detail Information

Publications10

  1. ncbi Blood island formation: longstanding observations and modern interpretations
    Michael J Ferkowicz
    Herman B Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, Ind 46202, USA
    Exp Hematol 33:1041-7. 2005
    ....
  2. ncbi Endothelial cells in the early murine yolk sac give rise to CD41-expressing hematopoietic cells
    Weiming Li
    Department of Pediatrics, Herman B Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, IN 46202, USA
    Stem Cells Dev 14:44-54. 2005
    ..These results demonstrate that CD41-expressing definitive hematopoietic cells appear to arise from endothelial cells lining nascent capillaries in vivo...
  3. ncbi Whole embryo imaging of hematopoietic cell emergence and migration
    Michael J Ferkowicz
    Department of Pediatrics, Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, IN, USA
    Methods Mol Biol 750:143-55. 2011
    ..The methods employed to examine yolk sac hematopoiesis may be applied to hematopoietic cell emergence in the embryo proper or fetal liver in the generation of a complete map of hematopoietic ontogeny...
  4. ncbi Embryonic day 9 yolk sac and intra-embryonic hemogenic endothelium independently generate a B-1 and marginal zone progenitor lacking B-2 potential
    Momoko Yoshimoto
    Department of Pediatrics, Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, IN 46202, USA
    Proc Natl Acad Sci U S A 108:1468-73. 2011
    ..The results of these studies expand our knowledge of hemogenic endothelial sites specifying distinct B-1 and MZ cell fates apart from B-2 cells and independent of an HSC origin during development...
  5. ncbi Identification of a novel hierarchy of endothelial progenitor cells using human peripheral and umbilical cord blood
    David A Ingram
    Department of Pediatrics, Herman B Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis 46202, USA
    Blood 104:2752-60. 2004
    ....
  6. ncbi Mitochondrial targeting of human O6-methylguanine DNA methyltransferase protects against cell killing by chemotherapeutic alkylating agents
    Shanbao Cai
    Section of Hematology/Oncology, Department of Pediatrics, Herman B Wells Center for Pediatric Research, Indiana University School of Medicine, 1044 West Walnut, R4-302C, Indianapolis, IN 46202, USA
    Cancer Res 65:3319-27. 2005
    ....
  7. ncbi CD41 expression defines the onset of primitive and definitive hematopoiesis in the murine embryo
    Michael J Ferkowicz
    Department of Pediatrics, Indiana University School of Medicine, Indianapolis, IN 46202, USA
    Development 130:4393-403. 2003
    ....
  8. ncbi Rac1 is essential for intraembryonic hematopoiesis and for the initial seeding of fetal liver with definitive hematopoietic progenitor cells
    Gabriel Ghiaur
    Department of Pediatrics, Cincinnati Children s Research Foundation and Cincinnati Children s Hospital Medical Center, and Hoxworth Blood Center, University of Cincinnati College of Medicine, OH, USA
    Blood 111:3313-21. 2008
    ..These data suggest that Rac1 plays an important role in HSC/P migration during embryonic development and is essential for the emergence of intraembryonic hematopoiesis...
  9. ncbi PECAM-1 is expressed on hematopoietic stem cells throughout ontogeny and identifies a population of erythroid progenitors
    Christina I Baumann
    Center for Hematologic Malignancies, Division of Hematology and Medical Oncology, Department of Medicine, Oregon Health and Sciences University UHN73C 3181 SW Sam Jackson Park Rd, 97239, USA
    Blood 104:1010-6. 2004
    ..These results demonstrate CD31 expression on hematopoietic stem cells throughout ontogeny and identify a population of CD31+ short-term erythroid progenitors cells that confer protection from lethal doses of radiation...
  10. ncbi Tumor necrosis factor-alpha and endothelial cells modulate Notch signaling in the bone marrow microenvironment during inflammation
    Luis Fernandez
    Center of Regenerative Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, Mass, USA
    Exp Hematol 36:545-558. 2008
    ....