Lawrence H Einhorn

Summary

Affiliation: Indiana University School of Medicine
Country: USA

Publications

  1. pmc Curing metastatic testicular cancer
    Lawrence H Einhorn
    Indiana University Medical Center, 535 Barnhill Drive, RT 473, Indianapolis, IN 46202 5289, USA
    Proc Natl Acad Sci U S A 99:4592-5. 2002
  2. ncbi request reprint Long-term survival after high-dose salvage chemotherapy for germ cell malignancies with adverse prognostic variables
    Daniel A Vaena
    Division of Hematology Oncology, Indiana University School of Medicine and Walther Cancer Institute, Indianapolis, IN, USA
    J Clin Oncol 21:4100-4. 2003
  3. ncbi request reprint Phase II study of paclitaxel plus gemcitabine salvage chemotherapy for germ cell tumors after progression following high-dose chemotherapy with tandem transplant
    Lawrence H Einhorn
    Division of Hematology Oncology, Indiana University School of Medicine, Walther Cancer Institute, Indianapolis, IN, USA
    J Clin Oncol 25:513-6. 2007
  4. ncbi request reprint Short- and long-term outcomes after large pulmonary resection for germ cell tumors after bleomycin-combination chemotherapy
    Rafael S Andrade
    Department of Surgery, Thoracic Division, Indiana University School of Medicine, Indianapolis, Indiana 46202, USA
    Ann Thorac Surg 78:1224-8; discussion 1228-9. 2004
  5. doi request reprint A 25-year single institution experience with surgery for primary mediastinal nonseminomatous germ cell tumors
    Kenneth A Kesler
    Department of Surgery, Cardiothoracic Division, Indiana University School of Medicine, Indianapolis, Indiana 46202, USA
    Ann Thorac Surg 85:371-8. 2008
  6. ncbi request reprint High-dose chemotherapy and stem-cell rescue for metastatic germ-cell tumors
    Lawrence H Einhorn
    Division of Hematology Oncology, Indiana University School of Medicine, Indianapolis, USA
    N Engl J Med 357:340-8. 2007
  7. ncbi request reprint Surgical salvage therapy for malignant intrathoracic metastases from nonseminomatous germ cell cancer of testicular origin: analysis of a single-institution experience
    Kenneth A Kesler
    Department of Surgery, Indiana Univeristy School of Medicine, Indianapolis, IN 46202, USA
    J Thorac Cardiovasc Surg 130:408-15. 2005
  8. ncbi request reprint Outcome analysis for patients with elevated serum tumor markers at postchemotherapy retroperitoneal lymph node dissection
    Stephen D W Beck
    Department of Urology, Indiana University School of Medicine, Indianapolis, IN 46202, USA
    J Clin Oncol 23:6149-56. 2005
  9. doi request reprint Salvage chemotherapy with high-dose carboplatin and etoposide with peripheral blood stem cell transplant in patients with relapsed pure seminoma
    Anuj K Agarwala
    Division of Hematology Oncology, Indiana University Melvin and Bren Simon Cancer Center, Indianapolis, IN 46202, USA
    Am J Clin Oncol 34:286-8. 2011
  10. ncbi request reprint Pathologic findings and therapeutic outcome of desperation post-chemotherapy retroperitoneal lymph node dissection in advanced germ cell cancer
    Stephen D W Beck
    Department of Urology, Indiana University School of Medicine, Indianapolis, IN 46202, USA
    Urol Oncol 23:423-30. 2005

Collaborators

Detail Information

Publications67

  1. pmc Curing metastatic testicular cancer
    Lawrence H Einhorn
    Indiana University Medical Center, 535 Barnhill Drive, RT 473, Indianapolis, IN 46202 5289, USA
    Proc Natl Acad Sci U S A 99:4592-5. 2002
    ..In the early 1970s, metastatic testicular cancer was associated with only 5% survival. Today, with modern chemotherapy and surgery techniques, 80% of patients will survive their disease...
  2. ncbi request reprint Long-term survival after high-dose salvage chemotherapy for germ cell malignancies with adverse prognostic variables
    Daniel A Vaena
    Division of Hematology Oncology, Indiana University School of Medicine and Walther Cancer Institute, Indianapolis, IN, USA
    J Clin Oncol 21:4100-4. 2003
    ..In this study, we evaluated outcomes at Indiana University and determined the applicability of the Beyer score to contemporary poor-risk patients...
  3. ncbi request reprint Phase II study of paclitaxel plus gemcitabine salvage chemotherapy for germ cell tumors after progression following high-dose chemotherapy with tandem transplant
    Lawrence H Einhorn
    Division of Hematology Oncology, Indiana University School of Medicine, Walther Cancer Institute, Indianapolis, IN, USA
    J Clin Oncol 25:513-6. 2007
    ..To determine long-term survival and potential cure with salvage chemotherapy with paclitaxel plus gemcitabine after progression after both cisplatin combination chemotherapy and subsequent high-dose chemotherapy with tandem transplantation...
  4. ncbi request reprint Short- and long-term outcomes after large pulmonary resection for germ cell tumors after bleomycin-combination chemotherapy
    Rafael S Andrade
    Department of Surgery, Thoracic Division, Indiana University School of Medicine, Indianapolis, Indiana 46202, USA
    Ann Thorac Surg 78:1224-8; discussion 1228-9. 2004
    ..We undertook an institutional review to determine the outcome of large pulmonary resections after bleomycin-combination chemotherapy...
  5. doi request reprint A 25-year single institution experience with surgery for primary mediastinal nonseminomatous germ cell tumors
    Kenneth A Kesler
    Department of Surgery, Cardiothoracic Division, Indiana University School of Medicine, Indianapolis, Indiana 46202, USA
    Ann Thorac Surg 85:371-8. 2008
    ..We reviewed our institution's 25-year experience in the cisplatin era to determine surgical risks and predictors of survival after surgery for PMNSGCT...
  6. ncbi request reprint High-dose chemotherapy and stem-cell rescue for metastatic germ-cell tumors
    Lawrence H Einhorn
    Division of Hematology Oncology, Indiana University School of Medicine, Indianapolis, USA
    N Engl J Med 357:340-8. 2007
    ..Metastatic testicular tumors that have not been successfully treated by means of initial chemotherapy are potentially curable with salvage chemotherapy...
  7. ncbi request reprint Surgical salvage therapy for malignant intrathoracic metastases from nonseminomatous germ cell cancer of testicular origin: analysis of a single-institution experience
    Kenneth A Kesler
    Department of Surgery, Indiana Univeristy School of Medicine, Indianapolis, IN 46202, USA
    J Thorac Cardiovasc Surg 130:408-15. 2005
    ..We reviewed our institution's experience with patients undergoing salvage operations to remove malignant intrathoracic metastases...
  8. ncbi request reprint Outcome analysis for patients with elevated serum tumor markers at postchemotherapy retroperitoneal lymph node dissection
    Stephen D W Beck
    Department of Urology, Indiana University School of Medicine, Indianapolis, IN 46202, USA
    J Clin Oncol 23:6149-56. 2005
    ..To evaluate the therapeutic benefit of postchemotherapy retroperitoneal lymph node dissection (PCRPLND) in patients with persistently elevated serum tumor markers...
  9. doi request reprint Salvage chemotherapy with high-dose carboplatin and etoposide with peripheral blood stem cell transplant in patients with relapsed pure seminoma
    Anuj K Agarwala
    Division of Hematology Oncology, Indiana University Melvin and Bren Simon Cancer Center, Indianapolis, IN 46202, USA
    Am J Clin Oncol 34:286-8. 2011
    ..To evaluate rates of complete remission and overall survival for patients with relapsed pure seminoma treated with high-dose carboplatin and etoposide followed by peripheral blood stem cell transplant...
  10. ncbi request reprint Pathologic findings and therapeutic outcome of desperation post-chemotherapy retroperitoneal lymph node dissection in advanced germ cell cancer
    Stephen D W Beck
    Department of Urology, Indiana University School of Medicine, Indianapolis, IN 46202, USA
    Urol Oncol 23:423-30. 2005
    ..Residual germ cell cancer was identified in 50% of patients, with a third alive at 5 years with no observed benefit from adjuvant chemotherapy. Select patients with increased tumor markers after chemotherapy are cured with surgery...
  11. ncbi request reprint Post chemotherapy RPLND in patients with elevated markers: current concepts and clinical outcome
    Stephen D W Beck
    Department of Urology, Indiana University School of Medicine, Indiana Cancer Pavilion, Indianapolis, IN 46202, USA
    Urol Clin North Am 34:219-25; abstract ix-x. 2007
    ..Predictors of death included rising preoperative betaHCG, elevated AFP, redo RPLND, and active germ-cell cancer in the resected specimen. Select patients with elevated tumor markers after chemotherapy are cured with surgery...
  12. doi request reprint Antiemetic therapy for multiple-day chemotherapy and additional topics consisting of rescue antiemetics and high-dose chemotherapy with stem cell transplant: review and consensus statement
    Lawrence H Einhorn
    Division of Hematology Oncology, Mel and Bren Simon Cancer Center, Indiana University, 535 Barnhill Room 473, Indianapolis, IN 46202 5289, USA
    Support Care Cancer 19:S1-4. 2011
    ..The results published reflect a consensus conference convened in Perugia, Italy. The topics discussed include antiemetic therapy of multiple-day chemotherapy, high-dose chemotherapy, and rescue antiemetics...
  13. doi request reprint Delayed effects of whole brain radiotherapy in germ cell tumor patients with central nervous system metastases
    Danielle M Doyle
    Department of Medicine, Division of Hematology and Oncology, Indiana University, Indianapolis, IN 46202, USA
    Int J Radiat Oncol Biol Phys 70:1361-4. 2008
    ..Our previous study did not observe serious CNS toxicity (Int J Radiat Oncol Biol Phys 1991;22:17-22). We now report on 5 patients who developed delayed significant CNS toxicity...
  14. ncbi request reprint Chemotherapeutic and surgical strategies for germ cell tumors
    Lawrence H Einhorn
    Division of Hematology Oncology, Indiana University Cancer Center, Walther Cancer Institute, Indianapolis, Indiana, USA
    Chest Surg Clin N Am 12:695-706. 2002
    ..The success of these studies confirms the importance of the continued search for new investigational drugs in all solid tumors...
  15. ncbi request reprint Is the blood-brain barrier relevant in metastatic germ cell tumor?
    Jose M Azar
    Department of Medicine, Division of Hematology and Oncology, Indiana University, Indianapolis, IN, USA
    Int J Radiat Oncol Biol Phys 69:163-6. 2007
    ..We propose to document that the BBB is also relevant in germ cell tumors despite their dramatic chemosensitivity...
  16. ncbi request reprint Is full bilateral retroperitoneal lymph node dissection always necessary for postchemotherapy residual tumor?
    Stephen D W Beck
    Department of Urology and Oncology, Indiana University Medical Center, Indianapolis, Indiana, USA
    Cancer 110:1235-40. 2007
    ..With the primary landing zone well defined in low-volume retroperitoneal disease, the authors performed modified dissections in the PC setting in a select population; and, herein, they report disease outcome...
  17. ncbi request reprint Palonosetron plus dexamethasone for prevention of chemotherapy-induced nausea and vomiting in patients receiving multiple-day cisplatin chemotherapy for germ cell cancer
    Lawrence H Einhorn
    Division of Hematology Oncology, Indiana University School of Medicine, Indiana University Cancer Center, 535 Barnhill Drive, Room 473, Indianapolis, IN, 46202 5289, USA
    Support Care Cancer 15:1293-300. 2007
    ..The aims of this study were to assess the safety and antiemetic efficacy of multiple-day dosing of palonosetron plus dexamethasone in patients receiving highly emetogenic multiple-day cisplatin-based chemotherapy for germ cell tumors...
  18. doi request reprint Long-term follow-up of Cisplatin combination chemotherapy in patients with disseminated nonseminomatous germ cell tumors: is a postchemotherapy retroperitoneal lymph node dissection needed after complete remission?
    Yaron Ehrlich
    Department of Urology and Division of Hematology Oncology, School of Medicine, Melvin and Bren Simon Cancer Center, Indianapolis, IN, USA
    J Clin Oncol 28:531-6. 2010
    ..In an attempt to address this question, we report the long-term follow-up of patients treated at Indiana University who were observed without PC-RPLND...
  19. doi request reprint Salvage therapy with high-dose chemotherapy and peripheral blood stem cell transplant in patients with primary mediastinal nonseminomatous germ cell tumors
    Yaman Suleiman
    Department of Oncology Hematology, Indiana University Melvin and Bren Simon Cancer Center, Indianapolis, Indiana 46202, USA
    Biol Blood Marrow Transplant 19:161-3. 2013
    ..In our opinion, salvage surgical resection if anatomically feasible is the preferred option for patients with PMNSGT progressing after initial chemotherapy...
  20. doi request reprint The "growing teratoma syndrome" in primary mediastinal nonseminomatous germ cell tumors: criteria based on current practice
    Kenneth A Kesler
    Cardiothoracic Division, Department of Surgery, Melvin and Bren Simon Cancer Center, Indiana University Health, Indianapolis, IN 46202, USA
    J Thorac Cardiovasc Surg 144:438-43. 2012
    ..Criteria for the growing teratoma syndrome in patients with primary mediastinal nonseminomatous germ cell tumors have not been well established according to current practice...
  21. doi request reprint Survival after resection for metastatic testicular nonseminomatous germ cell cancer to the lung or mediastinum
    Kenneth A Kesler
    Department of Surgery, Cardiothoracic Division, Indiana University Melvin and Bren Simon Cancer Center, Indianapolis, Indiana 46202, USA
    Ann Thorac Surg 91:1085-93; discussion 1093. 2011
    ..We undertook an institutional review of testicular NSGCT patients who underwent operations to remove lung or mediastinal metastases after chemotherapy in the cisplatin era to determine outcomes...
  22. ncbi request reprint Prostate carcinoma presenting as multiple pulmonary nodules in an asymptomatic patient with a history of testicular nonseminomatous germ cell tumor
    Francis D Sheski
    Department of Medicine, Indiana University School of Medicine and the Walther Cancer Institute, Indianapolis, Indiana 46202 2879, USA
    Urology 62:748. 2003
    ..Whether the incidence of prostate carcinoma is significantly increased in patients treated previously for germ cell tumors is unclear. We report such a patient, who responded to combination androgen blockade therapy...
  23. ncbi request reprint Does retroperitoneal lymph node dissection have a curative role for patients with sex cord-stromal testicular tumors?
    Ashraf A Mosharafa
    Department of Urology, Indiana University School of Medicine, Indianapolis, Indiana 46202, USA
    Cancer 98:753-7. 2003
    ..The authors attempt to evaluate the role of retroperitoneal lymph node dissection (RPLND) in the management of patients with these malignant sex cord-stromal tumors...
  24. doi request reprint Long-term outcome for patients with high volume retroperitoneal teratoma undergoing post-chemotherapy surgery
    Stephen D W Beck
    Department of Urology and Oncology, Indiana University School of Medicine, Indianapolis, Indiana, USA
    J Urol 181:2526-32. 2009
    ..We determined outcomes in patients with testicular cancer with large volume (greater than 10 cm) retroperitoneal teratoma treated with post-chemotherapy retroperitoneal lymph node dissection...
  25. pmc Support service use and interest in support services among distressed family caregivers of lung cancer patients
    Catherine E Mosher
    Department of Psychology, Indiana University Purdue University Indianapolis, Indianapolis, IN 46202, USA
    Psychooncology 22:1549-56. 2013
    ..This study examined support service use and interest in support services among distressed family caregivers of patients recently entering comprehensive cancer care facilities...
  26. doi request reprint Randomized, double-blind, placebo-controlled, phase III cross-over study evaluating the oral neurokinin-1 antagonist aprepitant in combination with a 5HT3 receptor antagonist and dexamethasone in patients with germ cell tumors receiving 5-day cisplatin co
    Costantine Albany
    Melvin and Bren Simon Cancer Center, Indiana University School of Medicine, 535 Barnhill Dr, RT 473, Indianapolis, IN 46202, USA
    J Clin Oncol 30:3998-4003. 2012
    ....
  27. doi request reprint Gefitinib plus celecoxib in chemotherapy-naïve patients with stage IIIB/IV non-small cell lung cancer: a phase II study from the Hoosier Oncology Group
    Anuj Agarwala
    Indiana University, Indianapolis, Indiana, USA
    J Thorac Oncol 3:374-9. 2008
    ..Preclinical studies demonstrate significant interactions between the EGFR and cyclooxygenase 2 (COX-2) pathways and that simultaneous inhibition may have benefits over EGFR inhibitors alone...
  28. doi request reprint Is retroperitoneal histology predictive of liver histology at concurrent post-chemotherapy retroperitoneal lymph node dissection and hepatic resection?
    Niels Erik B Jacobsen
    Departments of Urology, Surgery and Medicine, Indiana University, Indianapolis, Indiana, USA
    J Urol 184:949-53. 2010
    ..We identified factors predicting liver histology in patients with nonseminomatous germ cell tumor undergoing concurrent post-chemotherapy retroperitoneal lymph node dissection and liver resection...
  29. ncbi request reprint Histology in mixed germ cell tumors. Is there a favorite pairing?
    Ashraf A Mosharafa
    Department of Urology, Indiana University School of Medicine, Indianapolis, Indiana, USA
    J Urol 171:1471-3. 2004
    ..It was our impression that such associations exist. Delineating concordant histological types may provide insight into the ontogeny of testicular tumors and also have important clinical implications...
  30. ncbi request reprint Phase II study of cisplatin plus epirubicin salvage chemotherapy in refractory germ cell tumors
    Pablo M Bedano
    Division of Hematology Oncology and Biostatistics, Indiana University Medical Center and Walther Cancer Institute, Indianapolis, IN, USA
    J Clin Oncol 24:5403-7. 2006
    ..This phase II clinical trial evaluated the combination of CIS plus epirubicin (CIS-EPI) in patients with metastatic germ cell tumors (GCT) not amenable to cure with standard salvage therapy...
  31. ncbi request reprint Secondary leukemias in refractory germ cell tumor patients undergoing autologous stem-cell transplantation using high-dose etoposide
    William Houck
    Indiana Cancer Pavilion, 535 Barnhill Dr, RT 473, Indianapolis, IN 46202 5289, USA
    J Clin Oncol 22:2155-8. 2004
    ..To quantify the risk of secondary leukemias in relapsed testicular cancer patients undergoing autologous stem-cell transplantation with high-dose etoposide...
  32. doi request reprint Primitive neuroectodermal tumors in patients with testicular germ cell tumors usually resemble pediatric-type central nervous system embryonal neoplasms and lack chromosome 22 rearrangements
    Thomas M Ulbright
    Department of Pathology, Indiana University School of Medicine, Indianapolis, IN, USA
    Mod Pathol 23:972-80. 2010
    ..Future treatment strategies should take these findings into account...
  33. ncbi request reprint Cisplatin, etoposide and either bleomycin or ifosfamide in the treatment of disseminated germ cell tumors: final analysis of an intergroup trial
    Stuart Hinton
    Department of Medicine, Indiana University Medical Center and The Walther Cancer Institute, Indianapolis, Indiana, USA
    Cancer 97:1869-75. 2003
    ....
  34. ncbi request reprint A retrospective analysis of locally advanced esophageal cancer patients treated with neoadjuvant chemoradiation therapy followed by surgery or surgery alone
    Kenneth A Kesler
    Department of Surgery, Thoracic Division, Indiana University School of Medicine, Indianapolis, Indiana 46202, USA
    Ann Thorac Surg 79:1116-21. 2005
    ..We conducted an institutional review of patients with locally advanced esophageal cancer who had complete pretreatment and surgical staging to identify variables predictive of outcome...
  35. doi request reprint Multimodality treatment of germ cell tumors of the mediastinum
    Kenneth A Kesler
    Department of Surgery, Cardiothoracic Division Indiana University School of Medicine, Indianapolis, IN 46202, USA
    Thorac Surg Clin 19:63-9. 2009
    ....
  36. ncbi request reprint Outcome of patients with residual germ cell or non-germ cell malignancy after resection of primary mediastinal nonseminomatous germ cell cancer
    Bryan P Schneider
    Divisions of Hematology Oncology, Indiana Cancer Pavilion, Indianapolis, IN 46202 5289, USA
    J Clin Oncol 22:1195-200. 2004
    ..To identify prognostic variables and outcomes in patients with primary mediastinal nonseminomatous germ cell tumor (PMNSGCT) with postchemotherapy resection of persistent cancer...
  37. doi request reprint Serum tumor markers in testicular cancer
    Yaron Ehrlich
    Department of Urology, School of Medicine, Melvin and Bren Simon Cancer Center, Indianapolis, IN 46292, USA
    Urol Oncol 31:17-23. 2013
    ..The integration of tumor markers in prognostic models as well as the significance of marker kinetics during chemotherapy is discussed...
  38. ncbi request reprint Weekly paclitaxel and gemcitabine in advanced transitional-cell carcinoma of the urothelium: a phase II Hoosier Oncology Group study
    Jinxing Li
    Division of Hematology Oncology and Biostatistics, Indiana University School of Medicine, Indianapolis, IN, USA
    J Clin Oncol 23:1185-91. 2005
    ..To evaluate the efficacy and toxicity of weekly paclitaxel and gemcitabine in patients with advanced transitional-cell carcinoma (TCC) of the urothelial tract...
  39. ncbi request reprint Phase II study of imatinib mesylate in chemotherapy refractory germ cell tumors expressing KIT
    Lawrence H Einhorn
    Department of Medicine, Division of Hematology Oncology, Indiana University, Indianapolis, Indiana and Walther Cancer Institute, Indianapolis, IN, USA
    Am J Clin Oncol 29:12-3. 2006
    ..This phase II study was conducted to determine the activity of imatinib (gleevec) in heavily pretreated patients with KIT-positive metastatic germ cell tumor...
  40. pmc Economic and social changes among distressed family caregivers of lung cancer patients
    Catherine E Mosher
    Department of Psychology, Indiana University Purdue University Indianapolis, Indianapolis, IN 46202, USA
    Support Care Cancer 21:819-26. 2013
    ..This study examined various economic and social changes among distressed family caregivers of lung cancer patients during the initial months of cancer care in the USA...
  41. pmc Summary report 7th Annual Targeted Therapies of the Treatment of Lung Cancer
    Lawrence H Einhorn
    Indiana Cancer Pavilion, Indianapolis, Indiana, USA
    J Thorac Oncol 3:545-55. 2008
  42. ncbi request reprint Antiemetic therapy for multiple-day chemotherapy and high-dose chemotherapy with stem cell transplant: review and consensus statement
    Lawrence H Einhorn
    Division of Hematology Oncology, Indiana University School of Medicine, Indianapolis, IN 46202 5289, USA
    Support Care Cancer 13:112-6. 2005
    ..However, the results do not appear as successful as for highly emetic standard-dose chemotherapy...
  43. ncbi request reprint Phase II study of ifosfamide plus daily oral etoposide in previously treated ovarian cancer: a Hoosier Oncology Group (HOG) study
    Montaser Shaheen
    Section of Hematology Oncology, Walther Cancer Institute, Indiana University Medical Center, Indianapolis, Indiana, USA
    Am J Clin Oncol 27:229-31. 2004
    ..The 1-year survival probability using Kaplan-Meier analysis was 0.8. In this small sample-size trial, we did not demonstrate an advantage to this combination regimen compared to these or other single agents...
  44. ncbi request reprint Mediastinal metastases from testicular nonseminomatous germ cell tumors: patterns of dissemination and predictors of long-term survival with surgery
    Kenneth A Kesler
    Department of Surgery, Indiana University School of Medicine, Indianapolis, Ind, USA
    J Thorac Cardiovasc Surg 125:913-23. 2003
    ....
  45. ncbi request reprint Emetic potential of daily oral etoposide
    Lawrence H Einhorn
    Division of Hematology Oncology, Indiana University School of Medicine, 535 Barnhill Drive, Rm 473, Indianapolis, IN 46202 5289, USA
    Support Care Cancer 14:1262-5. 2006
    ..However, oral etoposide is categorized as having moderate emetogenicity. Daily oral etoposide is used in refractory germ cell cancer patients. We prospectively evaluated the emetic potential of oral etoposide in this patient population...
  46. doi request reprint Extragonadal germ cell tumors: clinical presentation and management
    Costantine Albany
    Indiana University Simon Cancer Center, Indianapolis, Indiana 46202, USA
    Curr Opin Oncol 25:261-5. 2013
    ..The extragonadal germ cell tumors (EGCTs) represent a unique entity, and as such require specialized management. This review article will discuss the diagnosis, prognosis and treatment modalities for EGCTs...
  47. doi request reprint Signet ring cell carcinoma of the testis: clinicopathologic and molecular evidence for germ cell tumor origin--a case report
    Sean R Williamson
    Departments of Pathology and Laboratory Medicine, Indiana University School of Medicine, Indianapolis, IN 46202, USA
    Am J Surg Pathol 36:311-5. 2012
    ..This is the first report of testicular signet ring cell carcinoma of germ cell tumor derivation...
  48. ncbi request reprint Mediastinal germ cell tumors
    Kenneth A Kesler
    Department of Surgery, Indiana University School of Medicine, Indianapolis, Indiana 46202, USA
    Ann Thorac Surg 83:1915. 2007
  49. pmc Perceptions of masculinity and self-image in adolescent and young adult testicular cancer survivors: implications for romantic and sexual relationships
    Melissa Y Carpentier
    Indiana University School of Medicine, Indianapolis, IN, USA
    Psychooncology 20:738-45. 2011
    ..To examine adolescent and young adult (AYA) testicular cancer survivors' subjective understanding of the impact of cancer in adolescence and young adulthood, with a particular emphasis on romantic and sexual relationships...
  50. ncbi request reprint Update on late relapse of germ cell tumor: a clinical and molecular analysis
    David W George
    Department of Medicine, and Section of Hematology Oncology, Herman B Wells Center for Pediatric Research, Indiana University Medical Center, Indianapolis, IN, USA
    J Clin Oncol 21:113-22. 2003
    ..Analysis of patients with late relapse (LR) of germ cell tumor (GCT) with reports on clinical characteristics, outcomes, and molecular and cytogenetic features...
  51. ncbi request reprint Will we ever have personalized medicine for non-small cell lung cancer?
    Lawrence H Einhorn
    Division of Hematology Oncology, Indiana University School of Medicine and Walther Cancer Institute, Indianapolis, Indiana, USA
    J Thorac Oncol 1:737-9. 2006
  52. pmc Primary teratoma of the lesser sac: lesser sac teratoma
    Brandon M Hardesty
    Indiana University Simon Cancer Center, 535 Barnhill Drive, Indianapolis, IN 46202, USA
    Case Rep Oncol Med 2012:604571. 2012
    ..Finally, we discuss some of the etiologic theories behind extragonadal germ cell tumors and how they relate to teratomas in the lesser sac...
  53. ncbi request reprint Phase II study of paclitaxel plus gemcitabine in refractory germ cell tumors (E9897): a trial of the Eastern Cooperative Oncology Group
    Stuart Hinton
    Indiana University Medical Center and Walther Cancer Institute, Indianapolis, IN, USA
    J Clin Oncol 20:1859-63. 2002
    ..Paclitaxel and gemcitabine have shown activity as single agents in refractory germ cell tumors and can be combined with manageable toxicity...
  54. ncbi request reprint Coarctation of the aorta
    Rohit Dwivedi
    Department of Medicine, Indiana University School of Medicine, and the VA Medical Center, Indianapolis, Indiana, USA
    Cardiol Rev 10:196. 2002
  55. pmc Lung cancer, thyroid cancer or both: An unusual case presentation
    Costantine Albany
    Melvin and Bren Simon Cancer Center, Indiana University School of Medicine, Indianapolis, USA
    J Thorac Dis 3:271-3. 2011
    ..This is the first published case of primary lung adenocarcinoma with metastasis to thyroid and with EGFR mutation...
  56. ncbi request reprint Teratoma in the orchiectomy specimen and volume of metastasis are predictors of retroperitoneal teratoma in post-chemotherapy nonseminomatous testis cancer
    Stephen D W Beck
    Department of Urology, Indiana University School of Medicine, Indianapolis, USA
    J Urol 168:1402-4. 2002
    ..We determine if the absence of teratoma in the orchiectomy specimen is a reliable predictor of the absence of teratoma in the retroperitoneum at post-chemotherapy retroperitoneal lymph node dissection...
  57. ncbi request reprint Metachronous intracranial germinoma in a patient with a previous primary mediastinal seminoma
    Pablo M Bedano
    J Clin Oncol 24:2386-7. 2006
  58. ncbi request reprint Cis-diamminedichloroplatinum, vinblastine, and bleomycin combination chemotherapy in disseminated testicular cancer. 1997
    Lawrence H Einhorn
    J Urol 167:928-32; discussion 933. 2002
  59. ncbi request reprint Bleomycin, etoposide, and cisplatin for three cycles compared with etoposide and cisplatin for four cycles in good-risk germ cell tumors: is there a preferred regimen?
    Lawrence H Einhorn
    J Clin Oncol 24:2597-8; author reply 2598-9. 2006
  60. ncbi request reprint Gene expression profiling of early- and late-relapse nonseminomatous germ cell tumor and primitive neuroectodermal tumor of the testis
    Jun Sugimura
    Laboratory of Cancer Genetics, Van Andel Research Institute, Grand Rapids, Michigan 49503, USA
    Clin Cancer Res 10:2368-78. 2004
    ..To better understand the molecular mechanisms that underlay the development and progression of nonseminomatous germ cell tumor of testis (NSGCTT) as well as malignant transformation of teratoma and primitive neuroectodermal tumor (PNET)...
  61. ncbi request reprint Role of the urologist in metastatic testicular cancer
    Lawrence H Einhorn
    J Clin Oncol 25:1024-5. 2007
  62. ncbi request reprint Positron emission tomography scans in postchemotherapy seminoma patients with residual masses: a retrospective review from Indiana University Hospital
    DeQuincy A Lewis
    J Clin Oncol 24:e54-5. 2006
  63. ncbi request reprint Delayed emesis: moderately emetogenic chemotherapy
    Fausto Roila
    Medical Oncology Division, Policlinico Hospital, 06122 Perugia, Italy
    Support Care Cancer 13:104-8. 2005
    ..Only one of four randomized studies showed a statistically significant efficacy of 5-HT(3) antagonists. Finally, only weak evidence has been published on the efficacy of dopamine receptor antagonists...
  64. ncbi request reprint Consensus proposals for the prevention of acute and delayed vomiting and nausea following high-emetic-risk chemotherapy
    Mark G Kris
    Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
    Support Care Cancer 13:85-96. 2005
    ..Selective antagonists of the type 3 serotonin receptor (5-HT(3)) in combination with dexamethasone and aprepitant are the standard of care for the prevention of emesis following chemotherapy of high emetic risk...
  65. ncbi request reprint A phase II trial of olanzapine for the prevention of chemotherapy-induced nausea and vomiting: a Hoosier Oncology Group study
    Rudolph M Navari
    Walter Cancer Research Center, University of Notre Dame, 250 Nieuwland Science Hall, Notre Dame, IN 46556, USA
    Support Care Cancer 13:529-34. 2005
    ..Olanzapine is safe and highly effective in controlling acute and delayed chemotherapy-induced nausea and vomiting in patients receiving highly and moderately emetogenic chemotherapy...
  66. ncbi request reprint Clinical benefits of once-weekly epoetin alfa in anemic patients with colorectal cancer receiving chemotherapy
    Edward Chu
    Yale University School of Medicine, New Haven, Connecticut 06520, USA
    J Support Oncol 4:243-50. 2006
    ..Except for significantly higher QOL scores at baseline, results for the cohort of colorectal cancer patients were similar to those for patients with other cancer types in the main study population...
  67. doi request reprint Primary mediastinal germ cell tumor evolving into an extramedullary acute megakaryoblastic leukemia causing cord compression
    Govinda R Brahmanday
    William Beaumont Hospital, Royal Oak, MI, USA
    J Clin Oncol 26:4686-8. 2008